Ngaba wena okanye umntu osondeleyo kuwe unikwe iyeza i-Everolimus ngugqirha? Usenokuba ulifumene eli yeza phantsi kwegama elithi Afinitor okanye iZortress. Eli liyeza elibaluleke kakhulu nelinamandla. Yiyo loo nto kufuneka silumke kakhulu xa sisebenzisa eli yeza. Ngoko ke namhlanje siza kuthetha ngeli yeza i-Everolimus, into eliyenzayo, into ekufuneka uyilumkele xa ulisebenzisa, kunye nazo zonke iziphumo ebezingalindelekanga ngendlela elula necacileyo.
Luhlobo luni lonyango oluyi-Everolimus?
Ngamafutshane, i-Everolimus liyeza elinciphisa ukusebenza kwenkqubo yomzimba yethu yokuzikhusela . Le nkqubo yokuzikhusela, esebenza njengomkhuseli womzimba wethu, ngamanye amaxesha inokusebenza nxamnye nathi. Eli yeza linceda kakhulu ukulawula iimeko ezinjalo.
Eli yeza lisetyenziselwa iinjongo ezimbini eziphambili:
1. Unyango lomhlaza: I-Everolimus, engaphantsi kwegama lophawu lwe-Afinitor, isetyenziselwa ukunyanga iintlobo ezithile zomhlaza (ezifana nomhlaza wezintso, webele, kunye nomhlaza we-pancreatic). Isebenza ngokulawula ukukhula nokusasazeka kweeseli zomhlaza.
2. Emva kokufakelwa amalungu omzimba: I-Everolimus, engaphantsi kwegama lophawu lweZortress, inceda ekuthinteleni umzimba wethu ukuba ungalamkeli ilungu elitsha emva kokufakelwa izintso okanye isibindi. Ngenxa yokuba ilungu elitsha lingaqhelekanga emzimbeni, inkqubo yomzimba yokuzikhusela izama ukulihlasela. I-Everolimus ilawula loo nkqubo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uthathe amayeza
I-Everolimus liyeza elinobuthathaka. Ngoko ke, kubalulekile ukuba ugqirha wakho azi imbali yakho epheleleyo yezonyango ngaphambi kokuba akunike eli yeza. Qiniseka ukuba uxelela ugqirha wakho ukuba unezinye zezi meko zidweliswe ngezantsi.
| Imeko yempilo okanye ingxaki | Isizathu sokuba nexhala |
|---|---|
| Isifo seswekile | Eli yeza linokunyusa amanqanaba eswekile egazini. |
| Isifo sentliziyo okanye i-cholesterol ephezulu | Ukusebenza kwentliziyo kunokuchaphazeleka. |
| Ubuthathaka benkqubo yomzimba yokuzikhusela | Ekubeni eli yeza linciphisa ngakumbi amajoni omzimba, kufuneka wazise nabani na osele enobuthathaka. |
| Iintsholongwane ezikhoyo | Xelela ngazo naziphi na izifo, kuquka izifo ezibangelwa ziintsholongwane ezifana ne-chickenpox kunye ne-herpes. |
| Isifo sesibindi okanye sezintso | Umlinganiselo weyeza ungadinga ukutshintshwa. |
| Ukuncipha kwenani leeseli zegazi | Ukuba uneeseli ezimhlophe zegazi, iiplatelets, okanye iiseli ezibomvu zegazi ezisezantsi, kufuneka uxele ngoko. |
| Ukuzama ukukhulelwa/ukukhulelwa | Eli yeza linokuba yingozi kumntwana ongekazalwa. |
| Ukuba ngumama oncancisayo | Iyeza linokudluliselwa kumntwana ngobisi lwebele. |
| Ukufumana unyango lwemitha | Ukuba usandul’ ukufumana okanye usenza unyango lwe-radiation. |
Ndingayisebenzisa njani kanye kanye le yeza?
Kubaluleke kakhulu ukuthatha idosi echanekileyo, ngexesha elifanelekileyo, njengoko ugqirha emyalele.
- Ginya ipilisi yonke ngeglasi yamanzi. Musa ukuyiqhekeza, ukuyityumza, okanye ukuyihlafuna.
- Uhlobo lweZortress luhlobo lwamayeza oluthatha ngexesha elifanayo yonke imihla , nokuba uwathatha kunye nokutya okanye ngaphandle kokutya (umz., emva kokutya yonke imihla). Oku kuya kunceda umzimba wakho ugcine izinga lokufunxa elihlala lihleli.
- Okubaluleke kakhulu: Musa ukuthatha eli yeza kunye nejusi yegrapefruit nangasiphi na isizathu. Ijusi yegrapefruit ingayichaphazela kakhulu indlela eli yeza elisebenza ngayo.
- Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Kodwa ukuba sele kuza kufuneka uyithathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Ezinye izinto ezinokusebenzisana ne-Everolimus
I-Everolimus liyeza elinokunxibelelana namanye amayeza, ukutya okuthile, kunye nezongezo. Ngoko ke, xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (amiselwe ngabanye oogqirha, amayeza athengiswa ngaphandle kwemvume kagqirha, amayeza emifuno, iivithamini).
| Izinto ezinokubangela iingxaki | Imizekelo |
|---|---|
| Oko kungafanele kuthathwe | |
| Izitofu zokugonya iintsholongwane eziphilayo | Umzekelo: I-Maasles, i-mumps, i-rubella (MMR), ugonyo lwe-chickenpox. |
| Ezinye iziyobisi ezinokusebenzisana | |
| Amayeza okulwa nentsholongwane kaGawulayo okanye i-AIDS | - |
| Amanye amayeza okubulala iintsholongwane | I-Erythromycin, iClarithromycin |
| Izinto ezilwa nokungunda | I-Ketoconazole, i-Itraconazole |
| Amayeza e-cholesterol kunye noxinzelelo lwegazi | I-Simvastatin, iDiltiazem, iVerapamil |
| Amayeza e-migraines | ICarbamazepine, iPhenytoin |
| Okunye | I-Cyclosporine, iDexamethasone, iRifampin |
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa iyeza
Ukuncipha komzimba kunye nosulelo
Eli yeza lenza buthathaka amasosha omzimba wakho, likwenze ube sesichengeni sokufumana izifo, ingakumbi izifo. Ngoko ke, hlala kude nabantu abanomkhuhlane okanye umkhuhlane. Lumka xa usiya kwiindawo ezinabantu abaninzi. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, ukubanda, okanye umphimbo obuhlungu, musa ukuzinyanga kwaye uxelele ugqirha wakho ngoko nangoko.
Utyando kunye nokuphiliswa kwamanxeba
Ukuba uza kwenziwa utyando, kufuneka uxelele ugqirha wakho. I-Everolimus isenokulibazisa ukuphola kwenxeba. Oogqirha badla ngokucebisa ukuba uyeke amayeza iveki ngaphambi kotyando uze uwaqalise kwakhona kwiiveki ezimbini emva kotyando, xa inxeba selipholile kakuhle.
Ukukhulelwa kunye nokuchuma
Le yingxaki ebaluleke kakhulu.
- Abafazi: Musa ukukhulelwa ngelixa usela eli yeza kwaye kangangeeveki ezisi-8 emva kokuyeka ukusebenzisa eli yeza. Eli yeza linokulimaza kakhulu usana olungekazalwa.
- Amadoda: Musa ukuzama ukuba nguyise womntwana ngelixa usebenzisa eli yeza okanye iiveki ezi-4 emva kokuyeka ukusebenzisa eli yeza.
- Kwakhona, eli yeza linokubangela ukungasebenzi kakuhle kwesibeleko kwabanye abafazi kunye nokuncipha kwenani lesidoda kumadoda. Ukuba uneengxaki zokuzala, thetha nogqirha wakho ngaloo nto.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengayo nayiphi na iyeza, i-Everolimus inokubangela iziphumo ebezingalindelekanga. Ezinye zinzima, ngelixa ezinye zixhaphakile. Into ebalulekileyo kukwazi ezi zinto kwaye uthathe amanyathelo ngokukhawuleza ukuba kuyimfuneko.
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
|---|---|
| • Iimpendulo ze-allergy - ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi | • Ubunzima bokuphefumla, iintlungu zesifuba, ukukhohlela |
| • Umkhuhlane, ukubanda, umphimbo obuhlungu | • Umchamo omnyama, iintlungu zesisu |
| • Ukudumba okanye ukopha okungaqhelekanga | • Ukudumba kwezandla, iinyawo, namaqatha |
| • Iimpawu zeswekile ephezulu egazini - ukoma kakhulu, indlala, ukuchama rhoqo, ukudinwa kakhulu, ukubona izinto ezingaqhelekanga | • Ubunzima bokuchama |
| Xelela ugqirha wakho ukuba iyaqhubeka okanye iyakukhathaza. | |
| • Ukuqhinwa okanye urhudo | • Izilonda zomlomo ezomileyo okanye zomlomo |
| • Intloko ebuhlungu | • Isiyezi |
Umyalezo Wokuya Ekhaya
- I-Everolimus liyeza elinamandla elicinezela inkqubo yomzimba yokuzikhusela. Landela imiyalelo kagqirha wakho ngokuchanekileyo.
- Xelela ugqirha wakho ngazo zonke ezinye iindlela zonyango, iivithamini, kunye namayeza esintu owasebenzisayo.
- Musa ukulisebenzisa eli yeza kunye nejusi yegrapefruit nangasiphi na isizathu.
- Zikhusele kwiintsholongwane xa usebenzisa amayeza. Ukuba ubonakalisa iimpawu ezifana nomkhuhlane nokukhwehlela, funa ingcebiso kagqirha ngoko nangoko.
- Izilumkiso malunga nokukhulelwa nokuzala zibaluleke kakhulu. Thetha ngokukhululekileyo nogqirha wakho ngaloo nto.
- Ukuba ufumana iziphumo ebezingalindelekanga ezinzulu ezifana nobunzima bokuphefumla, ukudumba okugqithisileyo, okanye ukopha okungaqhelekanga, bonana nogqirha ngokukhawuleza.
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