Ngaba ngamanye amaxesha uziva ngathi amhlophe emehlweni akho atyheli kancinci? Okanye ngaba umhlobo wakho wakha wakubuza wathi, "Kutheni amehlo am etyheli?"? Xa oko kusenzeka, ngequbuliso uziva usoyika, "Owu, ngaba nam ndinayo i-jaundice?" Kuba sonke siyazi ukuba ukutyheli kwamehlo kunokuba luphawu lwengxaki ethile kwisibindi. Kodwa ayisiyo yonke i-jaundice ebangelwa sisifo sesibindi esibi. Namhlanje siza kuthetha ngemeko abantu abaninzi abanayo, kodwa loo nto ayiyonto yokoyika kakhulu. Yiyo leyo iGilbert Syndrome.
Ngamafutshane, yintoni iGilbert Syndrome?
I-Gilbert Syndrome ayisosifo sibi kakhulu. Sisifo esixhaphakileyo semfuza esidluliselwa kwizizukulwana ngezizukulwana. Khawuthelekelele ukuba iiseli ezibomvu zegazi emzimbeni wethu ziyafa ngokuhamba kwexesha. Emva koko, xa ziqhekeka, kuveliswa imveliso yenkunkuma etyheli ebizwa ngokuba yi-bilirubin . Ibonakala ngathi yinkunkuma eluhlaza ebolayo. Omnye wemisebenzi ephambili yesibindi sethu kukususa le mveliso yenkunkuma ebizwa ngokuba yi-bilirubin emzimbeni.
Abantu abane-Gilbert's Syndrome banenkqubo ecothayo yokususa i-bilirubin. Oku kungenxa yokuba isibindi sabo sinenqanaba eliphantsi le-enzyme enceda kule nkqubo. I-gene echaphazela oku ibizwa ngokuba yi-'UGT1A1'. Ukuze ube nale meko, kufuneka ukuba ufumene iikopi ezimbini zale gene itshintshiweyo, enye evela kumama wakho kunye nenye evela kutata wakho.
Ngamafutshane, kufana nomzi-mveliso osesibindini, apho inkunkuma ye-bilirubin isebenza kancinci. Ngoko ke ngamanye amaxesha le nto ityheli ebizwa ngokuba yi-bilirubin iqokelelana egazini. Kulapho amehlo nolusu lubonakala lutyheli. Sikwabiza oku ngokuba yi-jaundice . Kodwa khumbula, i-Gilbert's Syndrome ayisosifo esonakalisa isibindi kwaye asiyonto yokoyika.
Zithini iimpawu? Kutheni zibonakala ngequbuliso?
Ixesha elininzi, abantu abane-Gilbert's Syndrome ababonisi zimpawu. Le enzyme yanele ukulawula amanqanaba e-bilirubin emizimbeni yabo.
Kodwa kwezinye iimeko ezikhethekileyo, inqanaba le-bilirubin egazini liyanda kancinci. Kulapho amhlophe emehlweni naselusu ajika abe tyheli. Oku sikubiza ngokuba yi-jaundice. Ukuba ubona olu hlobo lokutyheli, ngokuqinisekileyo kuya kufuneka ubone ugqirha ukuze ufumane ukuba kukho enye imbangela enzulu.
Ngamanye amaxesha, oku kutyheli kunokuhamba neentloko ezibuhlungu, ukudinwa, kunye nokungonwabi esiswini.
Kutheni ke ngoko eli nqanaba le-bilirubin linyuka ngequbuliso? Kukho izizathu ezininzi ezithile ezichaphazela eli nqanaba. Makhe sibone ukuba zeziphi.
| Izinto ezibangela ukwanda kwamanqanaba e-bilirubin | Kwenzekani? |
|---|---|
| Uxinzelelo | Izinto ezifana novavanyo kunye neengxaki zomsebenzi zinokutshintsha iinkqubo zomzimba. |
| Ukuphelelwa ngamanzi emzimbeni | Xa ungaseli manzi aneleyo. |
| Ukutsiba ukutya | Xa uzila ukutya okanye ungatyi ngenxa yokuxakeka. |
| Iintsholongwane | Xa ufumana isifo esifana nomkhuhlane okanye umkhuhlane, umzimba wakho uyasilwa naso. |
| Ukuzilolonga okunzima | Xa umzimba wakho udiniwe kakhulu ukuba ungamelana nayo. |
| Utywala | Utywala bubangela uxinzelelo olungaphezulu kwisibindi. |
| Ukuya exesheni kwabasetyhini | Le meko inokubangelwa kukutshintsha kwehomoni. |
Ugqirha uyifumana njani le nto?
Rhoqo, umntu ufunyaniswa ene-Gilbert's Syndrome ngengozi. Mhlawumbi xa uvavanywa igazi ngenxa yesinye isifo, ugqirha wakho uqaphela ukuba inqanaba lakho le-bilirubin liphezulu kancinci kunesiqhelo. Kulapho ke bacinga ukuba kunjalo.
La manyathelo adla ngokulandelwa ukuze kufunyaniswe isifo:
- Uvavanyo lwegazi:Amanqanaba eBilirubin ayajongwa. Uvavanyo lokusebenza kwesibindi lwenziwa nokujonga ukusebenza kwesibindi. Oku kunokuthintela ezinye izifo zesibindi ezinzulu.
- I-Ultrasound Scan: Ngamanye amaxesha i-scan ingenziwa ukuqinisekisa ukuba akukho ngxaki zesibindi (ezifana namatye okanye amafutha amaninzi).
- Uvavanyo lweGene: Olu vavanyo lungenziwa ukuqinisekisa ukuba kukho utshintsho kwi-gene ye-`UGT1A1`. Nangona kunjalo, oku akwenziwa rhoqo.
- I-Biopsy yesibindi: Oku akwenzeki rhoqo ukuze kuhlolwe i-Gilbert Syndrome. Kwenziwa kuphela xa kukho urhanelwa lwesinye isifo esinzima.
Ngaba ikho indlela yonyango lweGilbert Syndrome? Simele senze ntoni?
Nazi iindaba ezimnandi. I-Gilbert's Syndrome ayisosifo esifuna unyango. Ukutyheli (i-jaundice) ebangelwa yiyo akuyi kubangela monakalo wexesha elide emzimbeni wakho.
Ngoko ke into ekufuneka siyenze kukuhlala kude kangangoko kunokwenzeka kwizinto ezibangela ukuba amanqanaba e-bilirubin anyuke kakhulu, esithethe ngazo ngaphambili.
- Musa ukutsiba ukutya. Yitya ngexesha elifanelekileyo.
- Sela amanzi amaninzi. Kubaluleke kakhulu ukusela ubuncinane iilitha ezi-2-3 zamanzi ngosuku.
- Nciphisa uxinzelelo. Phumla ingqondo yakho ngokucamngca, ukumamela umculo, okanye ukuzibandakanya kwinto oyithandayo.
- Lala kakuhle. Lala ubuncinane iiyure ezisi-7-8 ngosuku.
- Nciphisa okanye uyeke ngokupheleleyo ukusela utywala .
- Ziphephe imithambo ebangela uxinzelelo olukhulu emzimbeni. Izinto ezifana nokuhamba rhoqo kunye neyoga zilungile.
Umcimbi oxhalabisayo ngokukodwa!
Kulapho kufuneka ugxile khona kakhulu. Le enzyme inye eqhekeza i-bilirubin esibindini sethu ikwanceda ekususeni amanye amayeza emzimbeni. Ngenxa yokuba loo enzyme isebenza kancinci kancinci kumntu one-Gilbert's Syndrome, loo mayeza ahlala emzimbeni ixesha elide kwaye anokubangela iziphumo ebezingalindelekanga.
Njengomntu one-Gilbert's Syndrome, kubalulekile ukuthetha nogqirha wakho malunga namayeza amatsha owasebenzisayo.
Umzekelo, amayeza asetyenziswa rhoqo afana ne -acetaminophen (iPanadol, iParacetamol) awela kolu didi. Kukwakho namayeza afana ne-'Irinotecan', esetyenziselwa umhlaza, kunye ne-'Protease inhibitor', esetyenziselwa i-HIV kunye ne-Hepatitis C.
Ngoko ke, xa usiya kugqirha, kubaluleke kakhulu ukuthi, "NdineGilbert Syndrome." Emva koko ugqirha uya kukuqwalasela oko xa ekunika amayeza.
Umyalezo Wokuya Ekhaya
- I-Gilbert Syndrome ayisosifo esoyikwayo. Yimeko engenabungozi, yemfuza edluliselwa kwizizukulwana ngezizukulwana.
- Uphawu oluphambili kukutyheli kwamehlo nolusu (i-jaundice) ngexesha loxinzelelo, ukugula, okanye ukuzila ukutya.
- Le meko ayifuni unyango. Okufuneka ukwenze kukuphepha izinto ezibangela ukuba amanqanaba e-bilirubin anyuke.
- Ukuba amehlo okanye ulusu lwakho lujika lube tyheli, qiniseka ukuba ucela ingcebiso kagqirha ukuqinisekisa ukuba ayisosinye isifo esinzima.
- Ukuba uyazi ukuba uneGilbert's Syndrome, kubaluleke kakhulu ukwazisa ugqirha wakho ngaphambi kokuba uthathe naliphi na iyeza elitsha.
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