Ngaba wakha wazibuza ukuba amandla avela phi xa sisitya into efana neqhekeza lerayisi okanye isonka? Kwakhona, wakha wazibuza ukuba siwafumana njani amandla esiwadingayo ukuze sizilolonge, sibaleke, okanye sitsibe? Amandla esiwafumanayo ekutyeni esikutyayo agcinwa ndaweni ithile emzimbeni wethu ukuze siwasebenzise kamva. Kufana nokugcina ibhetri yefowuni yethu itshajiwe okanye ukuba netanki eyongezelelweyo yegesi emotweni yethu. Eyona ndlela imizimba yethu egcina ngayo amandla ibizwa ngokuba yi-glycogen, esithetha ngayo namhlanje.
Ngokulula nje, yintoni i-glycogen?
Ngamafutshane, i-glycogen luhlobo lwe-glucose egcinwe emizimbeni yethu. Cinga ngale ndlela. Ii-carbohydrate esizityayo, ezifana nerayisi, isonka, iitapile, iitapile ezimnandi, kunye neziqhamo, ziyagaywa kwaye ziguqulwe zibe yiswekile elula ebizwa ngokuba yi-glucose emizimbeni yethu. Le glucose ngumthombo oyintloko wamandla kwiiseli zomzimba wethu, ingakumbi ingqondo. Njengokuba imoto ifuna ipetroli ukuze isebenze, imizimba yethu ifuna i-glucose ukuze isebenze.
Ngoku, emva kokutya isidlo, i-glucose engaphezulu kunaleyo umzimba wethu uyidingayo ukuze ufumane amandla ifakwa egazini ngoko nangoko. Ngoko ke endaweni yokulahla nje le glucose eyongezelelweyo, umzimba wethu uyayiqokelela ngobuchule, uze ubophe amawaka ee-molecule ze-glucose ezincinci ukuze zenze i-molecule enkulu. Yiloo nto siyibiza ngokuba yi-glycogen.
Iglucose ifana nokubamba imali ezandleni zethu. Kodwa njengokufaka imali engaphezulu ebhankini, umzimba ugcina iglucose engaphezulu njenge-glycogen.
Le nkqubo yenzeka ngoncedo lweeproteni ezikhethekileyo ezibizwa ngokuba zii-enzymes.
- Inkqubo yokwenza i-glycogen kwi-glucose ibizwa ngokuba yi -Glycogenesis .
- Inkqubo yokuqhekeza i-glycogen egciniweyo ukuze kwenziwe i-glucose xa kufuneka ibizwa ngokuba yi -glycogenolysis .
Nangona la magama mabini esenokubonakala ngathi anzulu kakhulu, khumbula nje ukuba elinye lelokugcina, elinye lelokuthabatha kwindawo yokugcina.
Iglucose, iglycogen, kunye neglucagon: Yintoni umahluko phakathi kwezi zinto zintathu?
Abantu abaninzi bayabhideka kuba la magama mathathu avakala efana. Nangona kunjalo, la magama mathathu enza imisebenzi emithathu eyahlukileyo ngokupheleleyo. Makhe sijonge le theyibhile ingezantsi ukuze sikuqonde kakuhle oku.
| Igama | Kalula nje... | Umsebenzi ophambili |
|---|---|---|
| Iswekile | Le 'yipetroli' yomzimba wethu. Oko kukuthi, umthombo wayo oyintloko wamandla. Iswekile elula eyenziwe ngeecarbohydrates esizityayo. | Ukunika iiseli amandla akhawulezileyo, ingakumbi abaluleke kakhulu ekusebenzeni kwengqondo. |
| I-Glycogen | Le 'yibhanki yamandla' emizimbeni yethu. Oko kukuthi, indlela egcinwa ngayo iglucose. | Ukugcina i-glucose ukuze isetyenziswe xa sifuna amandla (umz., xa sizila ukutya, xa sisenza umthambo). |
| I-Glucagon | Le 'sisihluthulelo' sendlu yokugcina izinto. Oko kukuthi, i-hormone. | Xa amanqanaba eswekile egazini (iglucose) ehla, iveliswa yipancreas kwaye ixelela isibindi ukuba siphule i-glycogen size siyiguqule ibe yi-glucose. |
Ngaba uyawuqonda umahluko? Iglucose ngamandla. IGlycogen ngamandla agciniweyo. IGlucagon yihormone exelela umzimba ukuba ukhuphe amandla kwindawo yokugcina. Ihormone esebenza ngokuchasene noku, oko kukuthi, xa iswekile yegazi isanda, inceda ukuyigcina njenge-glycogen, yi -insulin .
Iphi i-glycogen egcinwa emzimbeni?
Umzimba wethu ugcina le ndawo ibalulekileyo yamandla kwiindawo ezimbini.
1. Isibindi: Isibindi sethu yindawo yokugcina izinto. Inxalenye enkulu yobunzima besibindi inokwenziwa yi-glycogen.
2. Izihlunu Zamathambo: Izihlunu ezisemzimbeni wethu zigcina i-glycogen eninzi. Ngenxa yokuba ubunzima bezihlunu bukhulu kunesibindi, zimalunga nesithathu kwisine kuphela se-glycogen iyonke yomzimba egcinwa kwizihlunu.
Ukongeza kwezi ndawo zimbini ziphambili, inani elincinci kakhulu le-glycogen ligcinwa kwizitho ezifana nobuchopho.
Ubungakanani be-glycogen emizimbeni yethu abuhlali bufana imini yonke. Buyatshintsha. Kukho izinto ezininzi ezichaphazela oku:
- Ubungakanani beecarbohydrate ozityayo:Xa usitya ukutya okutyebileyo kwiicarbohydrate, iivenkile zakho zeglycogen ziyagcwala.
- Izikhewu zeXesha lokutya: Ukuba uhlala iiyure ezininzi ungatyi, umzimba wakho uza kusebenzisa ezi ndawo zokugcina amandla, nto leyo ebangela ukuba amanqanaba e-glycogen ehle. Ngokwesiqhelo, ukuzila ukutya iiyure ezili-12-24 kuya kunciphisa i-glycogen egcinwe kwisibindi.
- Umthamo womthambo kunye nobunzima: Xa uzilolonga nzima, ingakumbi umthambo onamandla kakhulu, i-glycogen kwimisipha yakho iyaphela ngokukhawuleza.
Kwenzeka ntoni kwi-glycogen emzimbeni?
I-Glycogen egcinwe esibindini nakwimisipha yenza imisebenzi emibini eyahlukeneyo. Zombini zisebenza ngendlela ethile yobugovu.
Umsebenzi wokugcina i-glycogen esibindini
I-glycogen esesibindini ifana negridi yombane yesizwe esasaza amandla kulo lonke ilizwe. Iqhelekile emzimbeni wonke.
Umsebenzi oyintloko we-glycogen yesibindi kukugcina amanqanaba eglucose egazini ezinzile.
Ingqondo yethu ifuna ukunikezelwa rhoqo kweglucose. Ukuba iyancipha kancinci, siqala ukuziva sinesizungu kwaye singenazintloni. Ngoko ke, xa siphakathi kokutya okanye silele ebusuku, xa kungekho glucose intsha egazini, amanqanaba eswekile egazini lethu ayehla.
Ngeli xesha, i-pancreas yethu ivelisa i-hormone i-glucagon . Le hormone iya esibindini ize ithumele umyalezo othi, "Kulungile, ngoku yahlula i-glycogen egciniweyo uze wenze i-glucose uze uyikhuphele egazini." Isibindi emva koko senza i-glucose size siyikhuphele egazini. Loo glucose ihamba ngegazi iye emzimbeni wonke, ingakumbi engqondweni, isinika amandla afunekayo. Yiyo loo nto sinokuhlala siphaphile iiyure ezininzi singatyi.
Umsebenzi wee-glycogen ezigcinwe kwimisipha
I-glycogen ekwimisipha ifana nejenereyitha efumaneka endlwini kuphela. Isetyenziswa kuphela yiloo msipha.
Ii-glycogen ezigcinwe kwimisipha zizinto zobuqu kakhulu. Zisebenzisa loo glycogen kuphela ukunika amandla loo misipha. Aziyiqhekezi ukuze zenze i-glucose zize ziyifake egazini.
Xa sihamba, sibaleka, okanye siphakamisa iintsimbi, izihlunu zethu zifuna amandla amaninzi ukuze zenze naluphi na ushukumo. Ukuba sizama ukufumana la mandla kwi-glucose esegazini, i-glucose esegazini iya kuphela ngokukhawuleza.
Ngoko ke, indalo idale ngokumangalisayo indawo yokugcina amandla ngaphakathi kwezihlunu ezinokuzisebenzisa zona, oko kukuthi iindawo zokugcina i-glycogen. Nje ukuba siqale ukuzilolonga, izihlunu ziyayiqhekeza le glycogen ukuze zivelise amandla eziwadingayo.
Khawucinge ngomdlali wekhilikithi obaleka phakathi kokubaleka. Okanye umdlali obaleka iimitha ezili-100. Ngexesha lemisebenzi enzima kangaka, izihlunu zifuna amandla amaninzi ngephanyazo. Kulapho ke ezi venkile zeglycogen ziza kunceda khona. Yiyo loo nto abadlali bexelelwa ukuba batye ukutya okune-carbohydrate eninzi (ukulayisha ii-carbs) ngaphambi kokhuphiswano, ukuze bazalise ezi venkile ze-glycogen kangangoko.
Yintoni iGlycogen Storage Disease (GSD)?
Le yimeko engaqhelekanga kakhulu, ezuzwe njengelifa. Sithethe ngendlela imizimba yethu edinga ngayo iintlobo ezahlukeneyo zee-enzymes ukwenza i-glycogen nokuyiqhekeza ukuze kwenziwe i-glucose. Kumntu one-GSD, enye okanye ezingaphezulu kwezi enzymes azikho okanye azisebenzi kakuhle.
Ngenxa yoko, umzimba womntu awukwazi ukwenza, ukugcina, okanye ukuqhekeza i-glycogen ngokufanelekileyo xa kuyimfuneko. Oku kunokubangela umonakalo wesibindi, ubuthathaka bemisipha, kunye namanqanaba eswekile egazini aphantsi ngokuyingozi (hypoglycemia). Kukho iintlobo ezahlukeneyo ze-GSD, kuxhomekeke kukungabikho kwee-enzyme. Rhoqo, ezi mpawu ziqala ukubonakala ebuntwaneni.
Eyona nto ibalulekileyo kukuba le yimeko engaqhelekanga kakhulu, ngoko ke akukho mfuneko yokoyika.
Ngaba kukho iimvavanyo ezikhethekileyo zokujonga amanqanaba e-glycogen?
Akukho vavanyo lunye olunokulinganisa ngokuthe ngqo, "Ndingakanani i-glycogen emzimbeni wam?" Kuba, njengoko besitshilo ngaphambili, elo nqanaba lihlala litshintsha imini yonke, kuxhomekeke kwinto esiyityayo nento esiyenzayo.
Nangona kunjalo, ukuba iimpawu zakho zibonisa ingxaki kwi-metabolism yomzimba wakho ye-glycogen, ugqirha wakho unokucebisa ezinye iimvavanyo zokujonga iimeko ezifana ne-GSD.
| Uvavanyo | Ingaba ujonge kwintoni? |
|---|---|
| Uvavanyo lwegazi | Iiphaneli zomsebenzi wesibindi nezintso ziyajongwa. Amanqanaba eglucose egazini nawo ayajongwa. Abantu abane-GSD badla ngokuba namanqanaba eswekile egazini aphantsi. |
| I-Ultrasound yesisu | Oku kunceda ukujonga ukuba isibindi sikhulu na. Xa i-glycogen ingasetyenziswa kakuhle, inokuqokelelwa esibindini ize idumbe. |
| I-Biopsy yeTishu | Kuthathwa iqhekeza elincinci kakhulu lesicwili kwisibindi okanye kwimisipha kwaye kulinganiswa amanqanaba e-glycogen okanye e-enzyme. |
| Uvavanyo lweMfuzo | Olu vavanyo lungenziwa ukuqinisekisa ukuba kukho utshintsho lwezakhi zofuzo olunxulumene ne-GSD. |
Ukuba unamathandabuzo ngezi mpawu, eyona nto ingcono onokuyenza kukubona ugqirha wosapho lwakho uze uthethe ngayo.
Umyalezo Wokuya Ekhaya
- I-Glycogen yeyona ndlela iphambili yokugcina amandla emzimbeni wethu. Ifana 'nebhanki yamandla' yomzimba wethu.
- Ezi zigcinwa ikakhulu esibindini nakwimisipha.
- I-Glycogen esibindini inceda ukulawula amanqanaba eswekile egazini kwaye inike amandla emzimbeni wonke.
- I-glycogen ekwimisipha isetyenziselwa ukunika amandla ezo zihlunu, ingakumbi ngexesha lokuzilolonga.
- Ukuze ugcine amanqanaba e-glycogen asempilweni, ingakumbi ukuba ungumdlali wezemidlalo, kubalulekile ukutya ukutya okunesondlo okuneekhabhohayidreyithi ezaneleyo yonke imihla.
- Iingxaki ezinxulumene neGlycogen azixhaphakanga kakhulu, kwaye kubalulekile ukuthetha nogqirha wakho ukuba uneengxaki.
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