Ngaba umzimba wakho awuphenduli kakuhle kwi-insulin? (Ukuchasana ne-insulin) Masifunde ngayo ngokulula!

Namhlanje siza kuthetha ngegama elithethwa ngabantu abaninzi, kwaye liyoyikisa kancinci. Elo ligama elithi 'Insulin Resistance'. Mhlawumbi ugqirha wakho ukuxelele ngalo, okanye ukhe wafunda ngalo ndaweni ithile. Liyintoni ngokwenene? ​​Kutheni libaluleke kangaka? Masiqonde konke oku ngokulula.

Ngoko ke, yintoni 'i-Insulin Resistance'?

Ngamafutshane, ukuxhathisa i-insulin kwenzeka xa iiseli emzimbeni wakho, ingakumbi ezo zikwimisipha yakho, iiseli zamafutha, nesibindi, zingaphenduli kakuhle kwi-hormone ye-insulin. Oku kukwabizwa ngokuba kukungasebenzi kakuhle kwe-insulin.

Cinga ngayo, i-insulin yinxalenye ebalulekileyo yomzimba wethu. Ifana nomlawuli wethrafikhi emzimbeni wethu. Yiyo esinceda sithumele i-glucose, okanye iswekile esiyitya egazini lethu, kwiiseli zethu ukuze zenze amandla. Ngoku, kwenzeka ntoni xa iiseli zingayimameli kakuhle le insulin? Iswekile egazini ayinakungena kwiiseli kwaye iqokelelane egazini.

Kwenzeka ntoni ke ngoko? Kwenzeka ntoni kwi-pancreas?

Kulapho ke ingxaki iqala khona. I-pancreas yethu – ifektri ye-insulin yomzimba wethu – iyaqonda ukuba, "Owu, iswekile yegazi iyanda kakhulu, kwaye ayingeni kwiiseli." Ngoko ke yintoni eyenziwa yi-pancreas? Iqala ukwenza i-insulin engakumbi ukulawula amanqanaba aphezulu eswekile. Kufana nokutyhala ucango luvuleke xa lungakwazi ukuvula. Oku sikubiza ngokuba yi-hyperinsulinemia.

Okwexeshana, ukuba ipancreas inokuvelisa i-insulin engaphezulu ngale ndlela kwaye ilawule amanqanaba eswekile egazini, akukho ngxaki inkulu. Kodwa, kancinci kancinci, njengoko iiseli zisiya zixhathisa ngakumbi kwi-insulin, nokuba ipancreas ivelisa i-insulin engakanani na, ayanelanga. Kulapho amanqanaba eswekile egazini aqala ukuba phezulu rhoqo. Sibiza oku ngokuthi 'yi-hyperglycemia'.

Ingaba oku 'kuxhathisa i-insulin' kuyingozi? Zithini iziphumo ezinokubakho?

Ewe, ukuba uqhubeka nale nto, inokuba yingozi kancinci. Kuba, xa la manqanaba aphezulu eswekile egazini eqhubeka ixesha elide, unokuba 'ne-prediabetes'. Oko kuthetha ukuba usecicini lokufumana isifo seswekile. Emva koko, unamathuba amaninzi okufumana isifo seswekile sohlobo lwesibini.

Ayipheleli apho, le meko inxulunyaniswa nezinye iingxaki ezininzi zempilo:

• Ukutyeba kakhulu , ingakumbi amafutha amaninzi esiswini.
• Isifo sentliziyo , oko kuthetha isifo sentliziyo kunye neengxaki zemithambo yegazi.
• Isifo sesibindi se-steatotic esibangelwa kukungasebenzi kakuhle kwemetabolism , esasaziwa ngaphambili njengesifo sesibindi esinamafutha esinganxilisiyo.
• Isifo seMetabolic.Esi asisosifo sithile, kodwa yingqokelela yeempawu ezidibanayo. Umzekelo, izinto ezifana noxinzelelo lwegazi oluphezulu, iswekile ephezulu yegazi, ukunyuka kwamafutha esiswini, kunye nokungalingani kwe-cholesterol.
• I-Polycystic Ovary Syndrome (PCOS). Oku kukungalingani kwamahomoni okwenzeka kubafazi.

Ngubani onokuthi abe 'nokumelana ne-insulin'?

Inokwenzeka nakubani na. Akunyanzelekanga ukuba ube nesifo seswekile. Ngamanye amaxesha inokuba yeyokwexeshana. Umzekelo, ukuba uthatha ii-steroids okwethutyana ngenxa yesigulo esithile, unokuba nokumelana ne-insulin. Isenokuba yimeko engapheliyo, oko kuthetha ukuba yimeko yexesha elide.

Kukho izinto ezimbini eziphambili ekucingelwa ukuba zinefuthe koku:

1. Amafutha amaninzi emzimbeni , ingakumbi ajikeleze isisu sakho.

2. Ukungazilolongi umzimba , oko kuthetha ukungazivivinyi.

Kwakhona, ukuba umntu kusapho lwakho unesifo seswekile (ingakumbi isifo seswekile sohlobo lwesibini), isifo seswekile esingaphambi kwesifo seswekile, okanye iimeko ezifana ne-polycystic ovary syndrome (PCOS), usenokuba sengozini enkulu yokuba ne-insulin resistance.

Ukuxhathisa i-insulin kuqhelekile kubantu abanesifo seswekile sangaphambi kwexesha kunye nesifo seswekile sohlobo lwesibini. Abantu abanesifo seswekile sohlobo loku-1 nabo ngamanye amaxesha banokuba nokuxhathisa i-insulin.

Zithini iimpawu zoku? Sikwazi njani?

Nantsi ingxaki. Ixesha elininzi, ukuba i-pancreas yakho inokwenza i-insulin engakumbi kwaye ilawule amanqanaba eswekile egazini lakho, usenokungabi nazimpawu. Usenokungazi nokuba yintoni na.

Nangona kunjalo, ngokuhamba kwexesha, le meko inokuba mandundu ngakumbi. Iiseli ezikwipancreas ezenza i-insulin nazo ziqala ukuba buthathaka kancinci kancinci. Ekugqibeleni, ipancreas ayikwazi ukuvelisa i-insulin eyaneleyo. Kulapho ke amanqanaba eswekile egazini aqala ukunyuka kwaye iimpawu ziqala ukubonakala.

Xa amanqanaba eswekile egazini lakho ehlala ephezulu, unokufumana iimpawu ezifana nezi:

• Ukunciphisa umzimba ngaphandle kwesizathu
• Ndiziva ndidiniwe ngalo lonke ixesha
• Ndiziva ndinxaniwe ngaphezu kwesiqhelo
• Ukuchama rhoqo
• Ndiziva ndilambile ngaphezu kwesiqhelo
• Umbono ofipheleyo
• Usulelo lwe-yeast oluqhelekileyo (ingakumbi kwilungu lobufazi kwaye ngamanye amaxesha nakwimiphetho yesikhumba kubasetyhini)

Abantu abaninzi abane-prediabetes abanazo iimpawu, ngamanye amaxesha iminyaka. I-prediabetes isenokungabonakalisi zimpawu ide ifikelele kwi-type 2 diabetes. Nangona kunjalo, abanye abantu abane-prediabetes banokubonakalisa iimpawu ezifana nezi:

• Ukuba mnyama kwamakhwapha akho, umva wentamo yakho, kunye namacala omzimba wakho . Oku kubizwa ngokuba yi -acanthosis nigricans . Kubukeka ngathi luthuli, kodwa akulona uthuli.
• Amaqhuma amancinci eluswini .
• Utshintsho emehlweni . Oku kunokukhokelela ekonakaleni kwamehlo okunxulumene nesifo seswekile (i-diabetes-related retinopathy).

Kubalulekile: Ukuba unenye okanye ngaphezulu kwezi mpawu, qiniseka ukuba ubona ugqirha wakho. Kubaluleke kakhulu.

Kutheni siphuhlisa 'ukuxhathisa i-insulin'? Zithini izizathu?

Oososayensi basasebenza ukuze bafumanise ukuba oku kwenzeka njani kanye kanye. Okwangoku kuyaziwa ukuba ii-genes ezithile zinokwenza umntu abe namathuba amaninzi okanye angaphantsi okufumana ukuxhathisa i-insulin. Oogqirha bayazi nokuba imeko iba mandundu xa ubunzima busanda, kwaye ukunciphisa umzimba kunokunceda ukuyilawula ngandlela ithile.

Ngaphandle koko, kukho ezinye izizathu ezininzi.

Izizathu ezifunyenweyo

Ezi azizozizathu esizalwa nazo, kodwa zizizathu ezivela ebomini bethu.

• Amafutha amaninzi emzimbeni: Izazinzulu zikholelwa ukuba ukutyeba kakhulu yeyona nto ibangela ukunganyangeki kwe-insulin. Amafutha agcinwe esiswini nangaphakathi kwezitho zangaphakathi (amafutha e-visceral) andisa kakhulu umngcipheko.
• Ukungazilolongi: Xa uzilolonga, umzimba wakho uba buthathaka ngakumbi kwi-insulin. Ukuzilolonga kunceda izihlunu zakho zifunxe i-glucose egazini lakho, nto leyo enokubangela le meko.
• Ukutya: Ukutya ukutya okucutshungulwe kakhulu, ukutya okune-carbohydrate eninzi, kunye nokutya okunamafutha amaninzi agcweleyo kufunyenwe kunxulunyaniswa nokuxhathisa i-insulin.
• Amanye amayeza: Amanye amayeza, anjenge -steroids, amanye amayeza oxinzelelo lwegazi oluphezulu, kunye namayeza asetyenziselwa ukunyanga i-HIV, anokubangela ukunganyangeki kwe-insulin.

Iingxaki zeHormonal ezibangela ukunganyangeki kwe-insulin

Ezinye iingxaki zehomoni zinokuchaphazela nendlela umzimba osebenzisa ngayo i-insulin.

• I-Cushing's syndrome: Le yimeko engaqhelekanga. Yenzeka xa kukho i-hormone eninzi ebizwa ngokuba yi-cortisol emzimbeni. I-cortisol egqithisileyo iphazamisana nomsebenzi we-insulin.
• I-Acromegaly: Le yimeko engaqhelekanga kodwa imbi kakhulu. Yenzeka xa kukho i-growth hormone (GH) eninzi emzimbeni. Oku kunokubangela ukuba umzimba ungavumi ukumelana ne-insulin.
• I-Hypothyroidism: Oku kuthetha ukuba i-thyroid gland yakho ayisebenzi kakuhle, oko kuthetha ukuba ayivelisi iihomoni ze-thyroid ezaneleyo. Oku kuyayicothisa imetabolism yakho, nto leyo enokubangela ukunganyangeki kwe-insulin.

Iimeko zemfuza ezibangela ukuxhathisa i-insulin

Kukho izifo ezithile zemfuza ezifunyanwa njengelifa kwaye zinokubangela ukunganyangeki kwe-insulin. Ezi azixhaphakanga kakhulu. Imizekelo ibandakanya iimeko ezibizwa ngokuba yi-Type A insulin resistance syndrome kunye ne-Donohue syndrome.

Nezinye iimeko ezininzi zemfuza:

• I-Myotonic dystrophy: Olu luhlobo lobuthathaka bemisipha oluchaphazela izihlunu, amehlo, kunye namalungu enkqubo ye-endocrine.
• I-Alström syndrome: Le meko ibangela ukutyeba kakhulu kunye nesifo seswekile sohlobo lwesibini. Inokubangela nokulahlekelwa yimbono nokuva, i-cardiomyopathy evulekileyo, kunye nokuphefumla kancinci.
• I-Werner syndrome: Oku kubangela ukwaluphala ngokukhawuleza (progeria). Kuchaphazela izinto ezininzi emzimbeni, kuquka ukunganyangeki kwe-insulin.
• I-lipodystrophy ezuzwe njengelifa: Kule meko, umzimba wakho awusebenzisi okanye awugcini amafutha ngokufanelekileyo.

Oogqirha bayixilonga njani le nto?

Ukumelana ne-insulin kunzima ukuxilonga ngokuchanekileyo, kuba akukho vavanyo lucacileyo noluqhelekileyo lwalo. Njengoko bekutshiwo ngaphambili, ukuba i-pancreas yakho inokuvelisa i-insulin eyaneleyo ukulawula imeko, awuyi kuba nazimpawu.

Nangona kunjalo, xa ugqirha wakho ekrokrela le meko, uya kuqwalasela izinto ezininzi:

• Imbali yakho yezonyango (njengezifo zangaphambili kunye namayeza owathathayo)
• Imbali yempilo yosapho lwakho (ngaba kukho umntu kusapho lwakho onesifo seswekile okanye isifo sentliziyo?)
• Uvavanyo lomzimba
• Iimpawu ozichazayo

Zeziphi iimvavanyo ezenziwayo koku?

Ugqirha angenza uvavanyo lwegazi oluninzi, olufana nolu:

• Uvavanyo lweglucose: Uvavanyo lweglucose yeplasma yokuzila ukutya (FPG) okanye uvavanyo lweswekile yegazi oluqhelekileyo lunokukunceda ubone ukuba unesifo seswekile esingaphambi kokuba ukhulelwe, isifo seswekile sohlobo lwesibini, okanye isifo seswekile sokukhulelwa.
• Uvavanyo lwe-A1c: Oku kunokukuxelela ukuba amanqanaba eswekile egazini lakho ebenjani kwiinyanga ezintathu ezidlulileyo.
• Iphaneli yeLipid: Oku kulinganisa iintlobo ezahlukeneyo zamafutha (ezifana ne-cholesterol kunye ne-triglycerides) egazini lakho.

Ngoko ke, uyiphatha njani le nto? (Unyango)

Ayizizo zonke izinto ezibangela ukunganyangeki kwe-insulin ezinokunyangwa, njengemfuza kunye nobudala. Ke ngoko, unyango oluphambili kukwenza utshintsho kwindlela yokuphila.

Olu tshintsho kwindlela yokuphila lulandelayo:

• Yitya ukutya okunesondlo: Ugqirha wakho angakuxelela ukuba unciphise iicarbohydrates kunye namafutha angenampilo. Oku kuthetha ukunciphisa iswekile, inyama ebomvu, kunye nokutya okunesitatshi okucutshungulweyo. Endaweni yoko, angakuxelela ukuba utye imifuno, iziqhamo, iimbotyi, kunye neenkozo ezipheleleyo. Kwiproteni, intlanzi kunye nenkukhu zikhetho ezilungileyo.
• Umsebenzi womzimba: Ukwenza umthambo ophakathi yonke imihla kunceda kakhulu.Oku kwandisa ukusetyenziswa kweglucose egazini ukuze kufumaneke amandla, kwaye kwandisa uvakalelo lwe-insulin kwimisipha.
• Ukunciphisa umzimba ogqithisileyo: Kwezinye iimeko, ukunciphisa umzimba kunokunceda ekubuyiseleni ukumelana ne-insulin. Ugqirha wakho angathetha nawe ngeendlela zokukunceda unciphise umzimba.

Ngokuhamba kwexesha, olu tshintsho lwendlela yokuphila lunokubangela iziphumo ezifana nezi:

• Ukuncipha kokuxhathisa i-insulin
• Ukwehla kwamanqanaba eswekile egazini
• Uxinzelelo lwegazi oluphantsi
• Ukwehla kwamanqanaba e-triglyceride kunye ne-LDL (i-cholesterol embi)
• Amanqanaba aphezulu e-HDL (i-cholesterol elungileyo)

Ugqirha wakho angakuthumela kwingcali, njengogqirha wezondlo okanye i-endocrinologist. Baza kusebenzisana nawe ukuze benze isicwangciso sonyango esifanelekileyo kuwe.

Ngaba kukho iyeza elikhethekileyo loku?

Okwangoku, akukho nyango luthile lokunganyamezelani ne-insulin. Nangona kunjalo, ugqirha wakho unokukunika amayeza kwezinye iimeko zempilo onokuba nazo. Eminye imizekelo ibandakanya:

• Amayeza oxinzelelo lwegazi oluphezulu
• Amayeza afana neMetformin yesifo seswekile okanye isifo seswekile esingaphambi kwexesha
• Amayeza afana nama-statins okunciphisa i-cholesterol ye-LDL

Ngaba ukumelana ne-insulin kunokutshintshwa? (Ukuguquguquka)

Ekubeni zininzi izinto ezibangela oku, azizizo zonke izizathu ezinokuguqulwa. Nangona kunjalo, utshintsho kwindlela yokuphila lunokwenza umahluko omkhulu. Ukutya ukutya okunesondlo, ukuzilolonga rhoqo, kunye nokunciphisa umzimba ogqithisileyo kunokunceda ekunciphiseni ukuxhathisa kwakho i-insulin. Thetha nogqirha wakho malunga nento onokuyenza ukuze ukwazi ukulawula oku.

Ukutya kuchaphazela njani ukuxhathisa i-insulin?

Ukutya okutyayo kunempembelelo enkulu kwiswekile yakho yegazi kunye namanqanaba e-insulin. I-Glycemic Index (GI) sisilinganiselo sokuba ukutya okutyayo kunyusa ngokukhawuleza kangakanani amanqanaba eswekile egazini lakho.

Ukutya okune-GI ephezulu kudla ngokuba neecarbohydrates ezininzi kunye/okanye iswekile. Xa uzitya, amanqanaba eswekile egazini lakho anyuka ngokukhawuleza, kwaye udinga i-insulin eninzi ukuze uyihlise kwakhona. Ke ngoko, kufuneka uphephe ukutya iziselo ezininzi ezineswekile (isoda, iziselo ezithambileyo, iziselo zeziqhamo ezenziweyo) kunye nokutya okufana noku:

• Isonka (isonka esimhlophe)
• Amazambane
• Iintlobo zeenkozo onokuzitya kwisidlo sakusasa
• Ukutya okumnandi okufana neekhekhe kunye neebhisikithi
• Ezinye iziqhamo ezifana ne-watermelon kunye needati (ezi zineswekile eninzi)

Xa usitya ukutya okune-GI ephantsi , inqanaba leswekile egazini lakho linyuka kancinci. Oku kuthetha ukuba i-pancreas yakho ayinyanzelekanga ukuba isebenze nzima ukuvelisa i-insulin. Ngokuqhelekileyo kungcono kubantu abanokuxhathisa i-insulin ukutya ukutya okune-GI ephantsi, okufana noku:

• Iimbotyi ezifana neembotyi, iitshizi kunye neelentile
• Iziqhamo ezifana nama-apile kunye namaqunube
• Imifuno engenasitatshi sininzi - imizekelo: i-asparagus, ikholifulawa, imifuno enamagqabi aluhlaza
• Amantongomane
• Ukutya kobisi, intlanzi, inyama

Khumbula: Soloko uthetha nogqirha wakho ngaphambi kokuba wenze naluphi na utshintsho olukhulu kwindlela otya ngayo. Angakunika iingcebiso ngeyona ndlela ilungileyo onokuyisebenzisa.

Ziziphi izinto ezibangela umngcipheko wokuxhathisa i-insulin? (Izinto ezibangela umngcipheko)

Ezinye izinto ezibangela umngcipheko kwimfuza kunye nendlela yokuphila zinokunyusa umngcipheko wokuba ne-insulin resistance okanye i-prediabetes. Ezi zinto ziquka:

• Ukutyeba kakhulu okanye ukutyeba kakhulu , ingakumbi amafutha amaninzi ajikeleze isisu.
• Uneminyaka engama-45 nangaphezulu.
• Ukuba nelungu losapho elisondeleyo (abazali, abantakwabo noodadewabo) abanesifo seswekile.
• Ukungawunyamezeli umzimba.
• Ukuba neemeko zempilo ezifana noxinzelelo lwegazi oluphezulu kunye ne-cholesterol ephezulu.
• Ukuba nesifo seswekile ngexesha lokukhulelwa (isifo seswekile sokukhulelwa).
• Ukuba nesifo sentliziyo okanye isifo sohlangothi.
• Iingxaki zokulala , umzekelo, i-sleep apnea.
• Ukutshaya.

Kwakhona, umngcipheko unokuba phezulu kancinci ukuba ungomnye wamaqela eentlanga:

• Mnyama
• I-Hispanic/Latino
• UmAsia
• Phakathi ENTSHONA

Asinakutshintsha ezinye izinto ezinokubangela umngcipheko, njengembali yosapho kunye nobudala. Nangona kunjalo, ungazama ukunciphisa umngcipheko wakho wokuba nale meko ngokugcina ubunzima obusempilweni obukufaneleyo kunye nokuzilolonga rhoqo.

Injani imbono yomntu onesifo sokunganyamezelani ne-insulin?

Ukuba unale meko, buza ugqirha wakho ukuba yintoni onokuyilindela kunye nendlela engcono yokuyilawula.

Indlela ocinga ngayo ixhomekeke kwizinto ezininzi:

• Isizathu sokuxhathisa i-insulin
• Ubunzima bokuxhathisa i-insulin
• Indlela wena nogqirha wakho eniyiphatha ngayo le meko

Abanye abantu banokuba nokumelana okuncinci kwe-insulin, okusenokungaze kuqhubekele kwi-prediabetes okanye isifo seswekile sohlobo lwesibini. Basenokuba nokumelana kwe-insulin okunokuguqulwa okanye kulawulwe ngokutshintsha indlela yokuphila.

Ziziphi iingxaki ezinokwenzeka ngenxa yokunganyamezelani ne-insulin?

Ukuba le meko ayiphathwa kakuhle, iingxaki zinokubakho. Iingxaki ezinokubakho ziquka:

• Uhlobo lwesibini lweswekile
• Isifo seMetabolic
• Isifo sentliziyo

Ayingabo bonke abantu abanesifo sokunganyamezelani ne-insulin abaya kuba neengxaki. Ukuba ufunyenwe unale meko, kubalulekile ukuzama ukuthintela ezi ngxaki. Qiniseka ukuba ubona ugqirha wakho rhoqo, kwaye ulandele isicwangciso sakho sonyango ngononophelo.

Ndifanele ndimbone nini ugqirha malunga nokunganyamezelani kwe-insulin?

Ukuba ufunyenwe unale meko, kubaluleke kakhulu ukubona ugqirha wakho rhoqo. Angajonga ukuba amanqanaba eswekile yakho egazini akwinqanaba elifanelekileyo kwaye unyango lwakho luyasebenza.

Ukuba uneempawu zeswekile ephezulu egazini okanye isifo seswekile esingaphambi kokuba umntu afumane isifo, bonana nogqirha wakho ngoko nangoko. Angenza uvavanyo olulula ukujonga amanqanaba eswekile egazini lakho.

Ukuba kukho umntu kusapho lwakho onesifo seswekile okanye ukunganyangeki kwe-insulin, thetha nogqirha wakho malunga nomngcipheko wakho wokuba nale meko.

Ndingayibuza yiphi imibuzo ugqirha?

Ukuba ufunyaniswe ukuba unale meko, kunokuba luncedo ukubuza ugqirha wakho le mibuzo:

• Yintoni ebangela ukuba ndingakwazi ukusebenzisa i-insulin?
• Ingakanani ingozi yam yokuba nesifo seswekile sangaphambi kwesifo seswekile okanye uhlobo lwesibini lwesifo seswekile?
• Ngaba kukho amayeza endingawaselayo?
• Ngaba kufuneka ndidibane nengcali yale meko?

Okokugqibela, izinto ekufuneka sizikhumbule (Umyalezo Wokuya Ekhaya)

Ngoko ke, sibonile ukuba ukuxhathisa i-insulin yimeko enzima kancinci, kwaye inokuchaphazela impilo yethu ngeendlela ezininzi. Rhoqo, ayibonisi zimpawu de ibe yi-prediabetes okanye i-type 2 diabetes.

Ngoko ke, eyona nto ingcono onokuyenza kukuzama ukuyithintela le meko, okanye ubuncinane uyibuyisele kwimeko yayo ukuba iyenzeka. Ukuze wenze oku , gcina ubunzima obusempilweni obukufaneleyo, qhelisa umzimba rhoqo, kwaye utye ukutya okunesondlo.

Nangona kunjalo, ngamanye amaxesha akunakwenzeka ukuthintela okanye ukunyanga zonke izinto ezibangela le meko. Ukuba unemibuzo malunga nomngcipheko wakho okanye malunga nale meko, qiniseka ukuba uthetha nogqirha wakho. Bakho ukuze bakuncede.

Ukuxhathisa i -insulin, isifo seswekile, isifo seswekile esingaphambi kokuba sivele, iswekile egazini, ipancreas, ukutyeba kakhulu, ukutya okunempilo, umthambo, iihomoni