Masifunde ngakumbi ngeLeptin, ekuncedayo ngasese ukulawula ubunzima bakho.

Sonke sixhalaba ngobunzima bethu ngamanye amaxesha, akunjalo? Abanye abantu bafuna ukunciphisa umzimba, ngelixa abanye befuna ukugcina ubunzima obusempilweni. Ngaba wakha wacinga ukuba kukho indlela encinci engaphakathi emizimbeni yethu esinceda silawule ubunzima bethu? I-Leptin ngomnye wabalawuli abayimfihlo. Namhlanje, masithethe ngale leptin ngendlela elula onokuyiqonda.

Yintoni iLeptin?

Ngamafutshane, i-leptin yi-hormone eveliswa ziiseli zamafutha emzimbeni wakho, okanye izicubu zamafutha . Ifana nenkqubo encinci yokubonisa ekuncedayo ukulawula ubunzima bakho ixesha elide. Ikwenza njani oko? I-Leptin ilawula indlala yakho kwaye ikwanceda uzive ugcwele, okanye unelisekile .

Cinga ngale ndlela: i-leptin ifana nesithunywa esixelela ingqondo yakho ukuba unamafutha angakanani emzimbeni wakho. Izazinzulu zifumene i-leptin kutshanje ngo-1994. Ngoko ke kusekho uphando oluninzi oluqhubekayo, ukuqonda kakuhle indlela esebenza ngayo. I-Leptin sele iphandwa ngendima yayo ekulawuleni ubunzima, isifo sika-Alzheimer , impilo yokuzala, kunye nokungazali .

Xa usiva ukuba i-leptin ilawula ubunzima, unokucinga, "Owu... ngoko ke ndicinga ukuba kufuneka ndifumane indlela yokulawula i-leptin." Kodwa, ukuba ndithetha inyani, ukulawula le hormone akulula njengoko ucinga.

Kwenzeka ntoni ngokwenene nge-leptin?

Umsebenzi ophambili weLeptin kukukunceda ugcine ubunzima bomzimba wakho. Oko kukuthi, inceda ekudaleni ibhalansi yexesha elide phakathi kobungakanani bokutya okutyayo kunye nobungakanani bamandla asetyenziswa ngumzimba wakho. ILeptin ikuthintela ekubeni uzive ulambile ngalo lonke ixesha. Ikwalawula nemiqondiso yendlala eza xa umzimba ungadingi mandla, okanye iikhalori .

I-Leptin isebenza ngokuyintloko ngokuchaphazela inxalenye yengqondo yakho ebizwa ngokuba yi-hypothalamus . I-hypothalamus yindawo ephambili yokulawula indlala nokusetyenziswa kwamandla. Nangona kunjalo, kukho ii-receptor ze-leptin kwezinye iindawo zomzimba.

Into ebalulekileyo kukuba i-leptin ayilawuli nje kuphela amanqanaba okulamba kwakho ukusuka kwesinye isidlo ukuya kwesinye. Endaweni yoko, inceda ukutshintsha iindlela zakho zokutya ngokuhamba kwexesha, ilawule indlela osebenzisa ngayo amandla, kwaye ikuncede ugcine ubunzima obuzinzileyo.

Xa uzama ukunciphisa umzimba, amanqanaba e-leptin ayanda. Isebenza njani loo nto? Njengoko umzimba wakho ulahlekelwa ngamafutha, amanqanaba e-leptin ayancipha. Oku kuthumela umyalezo emzimbeni wakho, othi, "Owu, andityi ngokwaneleyo, ndilambile." Oku kukwenza uzive ulambile kakhulu kwaye unqwenela ukutya. Oku kunokubangela ukuba utye ngaphezu kokuba kufanele. Yiyo loo nto ngamanye amaxesha kunokuba nzima ukugcina ukwehla kobunzima.

Izazinzulu zisafunda nge-leptin. Zikholelwa ukuba ikwachaphazela:

• I-metabolism yakho
• Inkqubo ye-endocrine, oko kukuthi, inkqubo ye-hormone
• Inkqubo yomzimba

Amanqanaba e-leptin alawulwa njani?

I-Leptin iveliswa kwaye ikhutshwa zizicubu ezimhlophe zamafutha emzimbeni wakho, okanye iiseli ezimhlophe zamafutha. Ezi seli zamafutha ezimhlophe zezona ntlobo ziphambili zamafutha emizimbeni yethu.

Ngenxa yokuba i-leptin ivela kwiiseli zamafutha, ubungakanani be-leptin egazini lakho bunxulumene ngokuthe ngqo nobungakanani bamafutha emzimbeni wakho. Ngamafutshane, ukuba unamafutha omzimba amancinci, une-leptin encinci. Ukuba unamafutha omzimba amaninzi, une-leptin eninzi.

Ukuba ubunzima bamafutha emzimbeni wakho buyanda ngokuhamba kwexesha, amanqanaba e-leptin ayanda. Ngokwahlukileyo koko, ukuba ubunzima bamafutha emzimbeni wakho buyancipha, amanqanaba e-leptin ayancipha.

Kuthekani ukuba amanqanaba e-leptin ayanda?

Umntu otyebileyo unokuba namanqanaba aphezulu kakhulu e-leptin emzimbeni wakhe. Oku kubizwa ngokuba yi -hyperleptinemia . Xa i-leptin isanda ngale ndlela, kunokwenzeka imeko apho umzimba ungaphenduli kwi-leptin. Oku kubizwa ngokuba yi-leptin resistance .

Ezinye iimeko ezinokunxulunyaniswa ne-hyperleptinemia ziquka:

• Uxinzelelo
• Ukuxhomekeka ekutyeni
• Iingxaki ze-Neurodegenerative
• Isifo sesibindi esinamafutha esinganxilisiyo ( NAFLD )
• Isifo sikaRabson-Mendenhall

Yintoni iLeptin Resistance?

Ukuba une-leptin resistance, ingqondo yakho ayiphenduli kwi-leptin ngokuqhelekileyo. Nangona i-leptin iqhubeka nokuthumela imiqondiso engqondweni yakho, awufumani uvakalelo "lokugcwala". Ngenxa yoko, uyaqhubeka nokutya, nangona unamafutha amaninzi emzimbeni wakho.

Ngenxa yokunqongophala kwe-leptin, umzimba wakho ucinga ukuba "ulambile." Ukuze wonge amandla, ingqondo yakho yehlisa amanqanaba akho amandla kwaye yehlise inani leekhalori ozitshisayo ngelixa uphumle. Oku kuthetha ukuba iBasal Metabolic Rate yakho (BMR) iyehla.

Ngoko ke, ukumelana ne-leptin kukwenza uzive ulambile ngalo lonke ixesha, kwaye ne-BMR yakho nayo iyancipha. Oku kwenza ukutyeba kube mandundu.

Oososayensi okwangoku bazama ukuvelisa amayeza anokunyanga ukuxhathisa i-leptin.

Iimpawu zokuxhathisa i-leptin

Iimpawu eziphambili zokuxhathisa i-leptin kukuhlala ulambile, okanye i-hyperphagia , kunye nokutya okuninzi. Ezi mpawu zenzeka xa unamafutha amaninzi emzimbeni, mhlawumbi namafutha amaninzi.

Nangona kunjalo, ezi mpawu zinokubangelwa zezinye izinto ezininzi, kungekuphela nje ukuxhathisa i-leptin. Njengoko izazinzulu zisafunda nge-leptin, kusenokwenzeka ukuba iimpawu ezingakumbi zokuxhathisa i-leptin ziya kufunyanwa kwixesha elizayo.

Kuza kwenzeka ntoni ukuba uneLeptin Deficiency?

Ukunqongophala kweLeptin, okwaziwa ngokuba yi- hypoleptinemia, yimeko engaqhelekanga kakhulu. Eyona meko iphambili enxulunyaniswa noku kukungabikho kwe-leptin ezalwa nayo. Le yimeko yemfuza ozalwa unayo. Oku kuthetha ukuba izicubu zakho zamafutha azikwazi ukwenza i-leptin.

Xa i-leptin ilahlekile, umzimba wakho ucinga ukuba akukho mafutha emzimbeni. Oku kubangela indlala neminqweno engalawulekiyo. Ngenxa yesi sizathu, abantwana abancinci abazalwa benesifo se-leptin bakhula ngokutyeba kakhulu kwiklasi yesi-3 kwaye bafikise ixesha elide ebusheni.

Le meko inxulunyaniswa nezinye izifo ezininzi:

• I-Dyslipidemia (ukungalingani kwamafutha, njenge-cholesterol kunye ne-triglycerides)
• Isifo sesibindi esinamafutha
• Usulelo oluqhelekileyo lweebhaktheriya
• I-Hyperinsulinemia (ukuveliswa kwe-insulin egqithisileyo)
• I-hypogonadotropic hypogonadism (amanqanaba aphantsi ehomoni yesini)

Ungayijonga njani inqanaba le-leptin?

Uvavanyo lwegazi lunokujonga amanqanaba akho e-leptin. Nangona kunjalo, oogqirha abaqhele ukujonga amanqanaba e-leptin yomntu wonke. Bacinga kuphela ngokwenza uvavanyo lwe-leptin kwezi meko:

• Ukuba umntwana wakho omncinci utyebile kakhulu kwibanga lesi-3
• Ukuba utyebile kakhulu kwaye uhlala uziva ulambile

Athini amanqanaba aqhelekileyo e-leptin?

Ngokwesiqhelo, amanqanaba e-leptin anokuhluka ukusuka ku:

• Kwabasetyhini: 0.5 ukuya kwi-15.2 nanograms nge-milliliter ( 0.5 ukuya kwi-15.2 ng/mL )
• Kumadoda: 0.5 ukuya kwi-12.5 nanograms nge-milliliter ( 0.5 ukuya kwi-12.5 ng/mL )

Nangona kunjalo, la maxabiso aqhelekileyo anokwahluka kancinci kwilabhoratri nganye. Ngoko ke, qiniseka ukuba ujonga uluhlu oluqhelekileyo kwingxelo yakho yovavanyo, okanye ubuze ugqirha wakho ukuba unemibuzo malunga neziphumo zakho.

Ndingawanyusa njani amanqanaba e-leptin yam?

Enyanisweni, akukho nto ingako onokuyenza ukwandisa amanqanaba akho e-leptin ukuze unciphise indlala okanye umnqweno wokutya. Kungenxa yokuba amanqanaba akho e-leptin anxulumene ngokuthe ngqo nobungakanani bezicubu zamafutha onazo emzimbeni wakho.

Olunye uphando lufumanise ukuba abantu abangalali ngokwaneleyo banamanqanaba aphezulu e-ghrelin (i-hormone yendlala) kunye namanqanaba aphantsi e-leptin. Ngoko ke, ukulala ngokwaneleyo kunokunceda ukugcina ii-hormone zakho zilungelelene.

Izazinzulu zidibanise i-leptin kunye ne -triglycerides(Olu lukwaluhlobo lwamafutha abizwa ngokuba yi-lipids). Ezinye izifundo zibonise ukuba xa amanqanaba e-triglyceride ephezulu, ichaphazela indlela esebenza ngayo i-leptin. Kodwa kukho izimvo ezahlukeneyo malunga nezi zifundo. Ezinye izazinzulu zicinga ukuba ukutya okwenzelwe ukunciphisa i-triglycerides kunokunceda ukonyusa amanqanaba e-leptin, kodwa ezinye azivumelani.

Ziziphi ukutya okune-leptin eninzi?

I-Leptin yi-hormone eyenziwa ngumzimba wakho, ayisiyo isondlo esifana ne-vitamin C okanye iproteni. Ke ngoko, akukho kutya kune-leptin.

Ngenxa yokuba i-leptin yinto entsha efunyenweyo, izazinzulu zisafunda okungakumbi ngayo, ingakumbi indlela echaphazela ngayo ukutyeba kakhulu kunye nokunciphisa umzimba. Xa amafutha omzimba wakho ephantsi, kunokuba nzima ukunciphisa umzimba ngenxa yendima ye-leptin ekusebenziseni uphawu "lwendlala" lomzimba.

Umyalezo Wokuya Ekhaya

Kulungile, ngoko ke kwinto esithethe ngayo nge-leptin, ungakhumbula oku:

• I-Leptin yi -hormone eveliswa ziiseli zakho zamafutha .
• Eyona nto iphambili ngale nto kukuba ikunceda ukulawula ubunzima bakho ekuhambeni kwexesha kwaye ikunika uvakalelo "lokuzaliswa" .
• Xa amafutha omzimba wakho esanda, amanqanaba e-leptin ayanda , kwaye xa amafutha omzimba wakho ehla, amanqanaba e-leptin ayancipha.
• Ukumelana ne-Leptin kwenzeka xa umzimba une-leptin kodwa ingqondo ingasabeli kakuhle kuyo. Oku kunokukhokelela ekutyebeni.
• Ukunqongophala kwe-Leptin kunqabile kakhulu .
• Akukho kutya kune-leptin, kuba iveliswa emzimbeni.
• Indlela yokuphila esempilweni, ingakumbi ukulala kakuhle , inokunceda ukulinganisela iihomoni.

Ukuba ukhathazekile ngobunzima bakho okanye ufuna ingcebiso malunga nendlela yokunciphisa umzimba ngendlela enempilo, thetha nogqirha wakho. Ungabonana nogqirha ogxile kwiihomoni, ingcali ye -endocrinologist, ukuze nixoxe ngeenkqubo zokulawula ubunzima. Eyona nto ibalulekileyo kukunyamekela impilo yakho kuqala.

I- Leptin, ulawulo lobunzima, iihomoni, ukutyeba kakhulu, ukumelana ne-leptin, indlala, ukuhlutha