Ngaba ugqirha wakho ukhe wayicebisa i-Nivolumab vaccine kuwe okanye kumntu osapho lwakho ukuze anyange umhlaza? Ngoko ke, masithethe ngokufutshane malunga nokuba yintoni le yeza, yintoni eliyenzayo, kunye nento ekufuneka uyiqaphele. Eli liyeza elintsonkothileyo, kodwa liphucuke kakhulu, ngoko ke kubalulekile ukuba uliqonde kakuhle.
Yintoni le nto yokugonyela iNivolumab?
Ngamafutshane, iNivolumab (edla ngokubizwa ngegama lophawu lwe-Opdivo) sisitofu sokugonya esikudidi olukhethekileyo lwamayeza abizwa ngokuba yi -monoclonal antibodies . Oku kuthetha ukuba yiproteni ekhethekileyo eyenzelwe ukuvuselela inkqubo yomzimba wethu yokuzikhusela, ukuyinceda ukuba ibone, ihlasele, kwaye itshabalalise iiseli zomhlaza. Ayifani ne-chemotherapy, kodwa isebenza ngendlela eyahlukileyo.
Eli yeza lisetyenziswa kakhulu ukunyanga iintlobo ezahlukeneyo zomhlaza. Ezinye zazo zezi:
- Umhlaza wamathumbu amakhulu
- Umhlaza wentloko nentamo
- I-lymphoma yeHodgkin
- Umhlaza wemiphunga
- I-Melanoma, uhlobo lomhlaza wolusu
Ugqirha wakho angakunika eli yeza nakwezinye iintlobo zomhlaza ezingekho kolu luhlu, ngoko ke thetha nogqirha wakho malunga nokuba eli liyeza elifanelekileyo na kuwe.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukunika ugqirha wakho inkcazo epheleleyo ngemeko yakho yempilo. Kuba ezinye iimeko zonyango zifuna unonophelo olukhethekileyo xa usebenzisa eli yeza. Qiniseka ukuba ukhankanya ezi zinto ngokukodwa:
- Ukuba unezifo ezihlasela umzimba , ezifana nesifo sikaCrohn, i-ulcerative colitis , okanye i-lupus.
- Ukuba ukhe wafakelwa i-allogeneic stem cell ngaphambili okanye uceba ukwenza enye.
- Ukuba sele ufumene unyango lwe-radiation kwindawo yesifuba sakho ngaphambili.
- Ukuba ukhe wafakelwa amalungu omzimba.
- Ukuba unesifo senkqubo yemithambo-luvo , esifana ne-myasthenia gravis okanye i-Guillain-Barre syndrome.
- Ukuba wakha waba ne-allergy kwi-Nivolumab okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa , oku kubaluleke kakhulu.
Indlela yokunika eli yeza kunye noko kufuneka ukuqaphele
Eli yeza linikwa wena ngemithambo yegazi (lifakwa emthanjeni). Le asinto onokuyenza ekhaya, kodwa yenziwa esibhedlele okanye eklinikhi phantsi kweliso labasebenzi bezonyango .
Ngaphambi kokuba uqale unyango, uza kunikwa incwadana ekhethekileyo (iMedGuide) equlethe ulwazi malunga nalo mayeza. Kubalulekile ukulifunda nokuliqonda ngononophelo ngaphambi kweseshoni nganye yonyango.
Cinga ngento onokuyenza ukuba uphoswe yidosi yamayeza. Kubaluleke kakhulu ukuya kugqirha wakho kanye ngemihla abakunika yona. Ukuba ngesizathu esithile awukwazi ukuya, fowunela iqela lakho lezonyango ngokukhawuleza uze ubazise.
Ukuba ucinga ukuba usele amayeza amaninzi kakhulu, yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele ngoko nangoko. Okanye utsalele umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Izinto ekufuneka ziqwalaselwe ngakumbi ngexesha lonyango
Ugqirha wakho uza kujonga imeko yakho ngokusondeleyo ngelixa usela la mayeza. Kuya kufuneka wenze uvavanyo lwegazi rhoqo.
Ingqwalasela ekhethekileyo malunga nokukhulelwa kunye nokuncancisa:
- Kwabasetyhini: Kuphephe ukukhulelwa ngelixa usela eli yeza kwaye emva kweenyanga ezi-5 emva kokuyeka iyeza. Oku kungonakalisa kakhulu impilo yomntwana. Ukuba uceba ukukhulelwa okanye ukrokrela ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko.
- Musa ukuncancisa umntwana wakho ngokupheleleyo ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezi-5 uyekile.
Iziphumo ebezingalindelekanga ezinokwenzeka ngeli yeza
Njengalo naliphi na iyeza, iNivolumab inokubangela iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Eyona nto ibalulekileyo kukwazi ezi mpawu kwaye uxelele ugqirha wakho ngoko nangoko ukuba ufumana naziphi na iimpawu ezinzulu.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Iingxaki zenkqubo yokugaya ukutya | Intlungu ebuhlungu esiswini, urhudo, igazi esitulweni, okanye isitulo esimnyama, esihlala ixesha elide. |
| Ubunzima bokuphefumla | Ukukhohlela okomileyo okungachazekiyo, ubunzima bokuphefumla. |
| Ukulimala kwesibindi | Intlungu kwicala eliphezulu lasekunene lesisu, ukuphelelwa ngumdla wokutya, isicaphucaphu, indle ekhanyayo, umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo okanye ulusu, ukudinwa okungaqhelekanga. |
| Ukulimala kwezintso | Ukuncipha kokuphuma komchamo, ukudumba kwamaqatha, izandla, okanye iinyawo. |
| Iingxaki ngeendlala zehomoni | Ukwanda kweehomoni ze-thyroid (i-Hyperthyroidism): Ukubetha kwentliziyo ngokukhawuleza, ukwehla kobunzima, ukubila kakhulu, ukungcangcazela, ukungazinzi. I-Hypothyroidism: Ukudinwa okungaqhelekanga, ukungakwazi ukunyamezela ingqele, ukuqhina, ukulahleka kweenwele, ulusu olomileyo, ukutyeba, ukudakumba. |
| Amanqanaba aphezulu eswekile egazini (i-Hyperglycemia) | Ukuziva unxaniwe kakhulu, ufuna ukuchama rhoqo, uzive udiniwe ngendlela engaqhelekanga, umbono ofipheleyo. |
| Ezinye iimpawu ezinzulu | Intlungu yesifuba, utshintsho lombono, iintlungu zamehlo, ukungaziva okanye iintlungu zamalungu omzimba, ubuthathaka bemisipha, ukulahleka kolungelelwano, ukudumba okanye ukuxobuka kwesikhumba, kuquka emlonyeni, ukukrweleka okanye ukopha okungaqhelekanga. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Ukudinwa | Ukudinwa |
| Isicaphucaphu nokuhlanza | Isicaphucaphu kunye nokuhlanza |
| Umnqweno wokutya | Ukulahlekelwa ngumdla wokutya |
| Ukuqhinwa | Ukuqhinwa |
| Intlungu emathanjeni | Intlungu yethambo |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona enye into eyahlukileyo okanye engaqhelekanga, thetha nogqirha wakho ngayo.
Umyalezo Wokuya Ekhaya
- I-Nivolumab sisitofu esikhethekileyo nesiphucukileyo esinceda amajoni omzimba ukuba atshabalalise iiseli zomhlaza.
- Ngaphambi kokuba uqale unyango, kubalulekile ukuba uxelele ugqirha wakho ngazo zonke iimeko zakho zempilo kunye namayeza owasebenzisayo.
- Lumka xa kukho iimpawu ezinobungozi (ingakumbi ubunzima bokuphefumla, urhudo olunzima, ukutyheli kolusu/amehlo, amadyungudyungu esikhumba). Funa ingcebiso kagqirha ngokukhawuleza ukuba ubona nayiphi na kwezi.
- Kubaluleke kakhulu ukuphepha ngokupheleleyo ukukhulelwa nokuncancisa ngelixa usebenzisa olu nyango kwaye emva kweenyanga ezi-5 emva kokuba uyekile.
- Ungaphoswa yimihla enikwe ngugqirha kwaye uye kunyango. Ungoyiki ukuthetha nogqirha ngayo nayiphi na imibuzo okanye iingxaki onazo.
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