Ngaba uhlala uziva udiniwe, unengxaki yokugaya ukutya rhoqo, okanye unesifo sorhudo esingachazekiyo? Ngaba ubona utshintsho olungaqhelekanga lolusu okanye unengxaki yokukhumbula izinto ezingalindelekanga? Nangona ezi mpawu zinokunxulunyaniswa neemeko ezahlukeneyo, zinokubonisa ingxaki ethile yempilo, edla ngokunganakwa. Namhlanje, sithetha ngemeko eyaziwa ngokuba yiPellagra .
Yintoni iPellagra?
Ngamafutshane, iPellagra sisifo esibangelwa kukungafumani ngokwaneleyo iNiacin , ekwaziwa ngokuba yiVitamin B3 . Olu luhlobo lokungondleki kakuhle—ingakumbi, ukunqongophala kwezakhamzimba. Umzimba wakho ufuna iNiacin ukuze isebenze kakuhle iiseli. Xa amanqanaba ehla, impembelelo ivakala kuyo yonke inkqubo yakho, ngakumbi eluswini, emlonyeni, kwindlela yokugaya ukutya, nasebuchotsheni. Ngaphandle kokungenelela ngokufanelekileyo kwezonyango, iPellagra inokukhokelela ekonakaleni kwemithambo-luvo ngokusisigxina kwaye, kwiimeko ezinzima, inokubulala.
Usenokuzibuza ukuba oku kuyabachaphazela bonke abantu na. Ngokwesiqhelo, abo batya ukutya okunesondlo bafumana iNiacin eyaneleyo. IPellagra eyintloko—ebangelwa kukungabikho kokutya okufanelekileyo—ibonakala kakhulu kwiindawo ezingakhuselekanga ekutyeni. Nangona kunjalo, kwiindawo eziphuhlileyo, kuquka neSri Lanka, ukunqongophala kweNiacin kudla ngokubangelwa zizizathu zesibini. Oku kuthetha ukuba ezinye iimeko zempilo okanye izinto ezibangela ukuba umzimba wakho ungafumani okanye usebenzise iNiacin oyityayo.
Yintoni iNiacin, kwaye kutheni uyidinga?
Cinga ngeNiacin njengesongezo samafutha esiqinisekisa ukuba "injini" yomzimba wakho isebenza ngokufanelekileyo. Njengokuba injini ifuna ipetroli ecociweyo ukuze isebenze, umzimba wakho udinga iNiacin ukuze icubungule iikhalori ozisebenzisayo zibe ngamandla asebenzisekayo.
Nje ukuba ifunxwe ngamathumbu amancinci, iNiacin iguqulwa ibe yi-coenzyme ebalulekileyo ebizwa ngokuba yiNicotinamide Adenine Dinucleotide (NAD) . I-NAD ixhasa ii-enzymes ezingaphezu kwama-400 emzimbeni wakho. Ngamafutshane, i-NAD ibalulekile ekuveliseni amandla eseli aziwa ngokuba yi- Adenosine Triphosphate (ATP) . Ngaphaya kokuveliswa kwamandla, i-NAD ibalulekile ekulungisweni kwe-DNA kunye nonxibelelwano lweseli.
Ukungabikho kweNiacin kuyichaphazela njani umzimba wakho?
Ngenxa yokuba i-NAD ibalulekile kumandla eeseli, ukunqongophala kwayo kuchaphazela iinkqubo ezineemfuno eziphezulu zamandla okanye ukuguquka ngokukhawuleza kweeseli: ulusu lwakho, ulwelo lwendlela yakho yokugaya ukutya, kunye nengqondo yakho. Oogqirha badla ngokuchaza iimpawu zePellagra njenge "3 Ds": Urhudo, iDermatitis, kunye neDementia. Abanye bongeza "D" yesine: Ukufa . Ukuba ayinyangwa ixesha elide, isiphumo singabulala.
1. Urhudo (Isifo sohudo)
Urhudo lwenzeka xa ulwelo olukhuselayo lomgudu wakho wokugaya ukutya lungaphumeleli ukuphinda lukhule ngokufanelekileyo. Ngaphandle kwesi sithintelo sokukhusela, amathumbu akho ayasokola ukugaya ukutya kwaye azikhusele kwizifo kunye nokwenzakala. Oku kukhokelela ekuvuvukeni okungapheliyo kuyo yonke indlela yokugaya ukutya, okubonakala njengentlungu yesisu, ukungagayi kakuhle, izilonda zomlomo, kunye nolwimi olubomvu oludumbileyo.
2. I-Dermatitis (Ukulunywa lusu)
I-Pellagra ibangela imeko yolusu eyahlukileyo, ingakumbi kwiindawo ezichatshazelwe lilanga ezifana nobuso, intamo, izandla, neenyawo. Ngaphandle kwamandla aneleyo eeseli, iiseli zolusu ziba buthathaka kakhulu ekukhanyeni kwe-UV. Ekuqaleni, ulusu lunokubonakala lubomvu kwaye lutshiswe lilanga, ekugqibeleni lube rhabaxa, lube namaxolo, kwaye luvelise iiplaque ezinombala ophezulu (amabala amnyama) . Uphawu oluphawulekayo lubhanti olungqindilili nolumnyama olujikeleze intamo olwaziwa ngokuba yi- "Casal's collar," oluthiywe ngugqirha uDon Gaspar Casal, owaqala ukuchonga esi sifo ngo-1735.
3. I-Dementia (Ukonakala kwengqondo kunye nemithambo-luvo)
Ngenxa yokuba iPellagra ichaphazela ukuveliswa kwamandla kwiseli nganye, ekugqibeleni ichaphazela ingqondo kunye nenkqubo yemithambo-luvo. Iimpawu zokuqala zinokuba zingabonakali, njengokudinwa okungapheliyo, ukungakhathali (ukungabi namdla), okanye ubunzima bokugxila. Usenokuba nexhala okanye ukudakumba.Ekuhambeni kwexesha, ezi mpawu zinokukhula zibe kukudideka nokungaziqondi kakuhle. Kwiimeko ezinzima, i-dementia engapheliyo inokwenzeka, kunye nokuphazamiseka kwemithambo-luvo njengokungalungelelani kakuhle, ukuphazamiseka kwendlela ohamba ngayo, ukuxinana kwemisipha, kunye nokungcangcazela.
Iphi iPellagra exhaphake kakhulu?
Ngokwembali, iPellagra yayixhaphake kakhulu phakathi kwabantu ababenokutya okulinganiselweyo, ingakumbi abo baxhomekeke kakhulu kumbona njengokutya okuqhelekileyo abangenazo izongezo ezicebileyo kwiproteni. Nangona umbona uneNiacin, ukho ngendlela "ebotshelelweyo" umzimba womntu ongenakuyifunxa ngokulula.
KuMbindi nakuMzantsi Merika, iindlela zemveli zokucubungula umbona ube ziitortilla ziquka ukumanzisa iinkozo emanzini ekalika. Le nkqubo ikhulula iNiacin ebotshelelweyo, nto leyo eyenza ukuba ifumaneke lula. Ngenxa yoko, iPellagra ( Pellagra ) ayifumaneki rhoqo kwezo ndawo.
Namhlanje, ukuqinisa izinto ezisisiseko ezifana nomgubo nerayisi kuye kunciphisa kakhulu iPellagra ephambili kwiindawo ezininzi zehlabathi. Nangona kunjalo, nangona kunqabile, kufuneka sihlale silumkile malunga nezizathu zesibini zePellagra. Ukuba ukrokrela ukuba unale mpawu, nxibelelana nesibhedlele esikufutshane okanye iinkonzo zikaxakeka ngokukhawuleza.
Zithini iimpawu zePellagra?
Nazi iimpawu eziqhelekileyo onokuzibona xa usebenzisa iPellagra:
- Urhudo oluhlala luhleli , olunokuba negazi ngamanye amaxesha.
- Intlungu yesisu kunye nokungagaywa kakuhle kwesisu.
- Ukuphelelwa ngumdla wokutya , isicaphucaphu , kunye nokuhlanza .
- Ulusu olurhawuzelelwayo okanye amaqhakuva abuhlungu eluswini .
- Izilonda zomlomo kunye nolwimi olubomvu oqaqambileyo noludumbileyo.
- Ukudinwa kakhulu, ubuthathaka, kunye nokuziva ungonwabanga.
- Utshintsho lweemvakalelo kunye nokudakumba.
- Iimpawu ze-neurological – umzekelo, ukungcangcazela kwamalungu okanye ukungaziva.
- Ukuphambana kwengqondo kunye neempawu zesifo sengqondo esixhalabisayo.
Zithini izizathu zePellagra?
Isizathu esiyintloko kukutya okungenayo i-niacin eyaneleyo (iVitamin B3). Nangona sifumana i-niacin kwiintlobo ngeentlobo zokutya, abantu abangenayo isondlo esifanelekileyo banokuswela.
Ukongeza, usenokuba ne-pellagra ngenxa yezizathu zesibini . Oku kuthetha ukuba umzimba wakho awukwazi ukufunxa okanye ukusebenzisa i-niacin ngokufanelekileyo ngenxa yemeko yempilo engaphantsi. Imizekelo ibandakanya:
- Izifo zesisu ezibangela ukungafunxwa kakuhle kwesisu – ezifana neSifo seNtsholongwane yokuQhamuka (IBD) okanye isifo sesibindi.
- Ingxaki yokusebenzisa utywala: Ukusela utywala kakhulu konakalisa amalungu omzimba anjengesibindi, kuphazamisa ukufunxwa kwezondlo ezibalulekileyo ezifana ne-niacin kwaye kukhokelela ekungondlekini kakuhle.
- Utyando lwesisu: Emva kotyando, umonakalo kwi-inside lining unokuphazamisa ukufunxwa kwezakhamzimba ezibalulekileyo, kuquka ne-niacin.
- I-anemia yokungabikho kwe-iron: Umzimba wakho udinga i-iron ukuze uguqule kwaye usebenzise i-niacin ngokufanelekileyo.
- Isifo sikaHartnup: Imeko yemfuza apho umzimba uzama ukufunxa ii-amino acid ezithile ezifunekayo ukuvelisa iivithamini.
- Isifo seCarcinoid:Iiseli ezithile zethumba zinokunciphisa ukuveliswa kwe-niacin emzimbeni.
- Amayeza athile: Ingakumbi amayeza okulwa noxinzelelo lwegazi kunye namayeza e-chemotherapy anokuphazamisana ne-niacin metabolism.
- Usulelo lwe-HIV: I-HIV inokubangela ukuba amanqanaba e-niacin aphantsi emzimbeni.
Ifunyanwa njani iPellagra?
Xa undwendwela ugqirha, baya kukuxilonga, bahlole iimpawu zakho, imbali yakho yezonyango, kunye nemikhwa yokutya. Ukuba ugqirha wakho urhanela ukuba une-pellagra, banokuyalela uvavanyo lomchamo ukuze kulinganiswe amanqanaba athile eekhemikhali, nto leyo enceda ekuqinisekiseni ukuba umzimba wakho ufumana i-niacin eyaneleyo. Ugqirha wakho unokukunika izongezo ze-niacin ukuze abone ukuba iimpawu zakho ziyaphucuka na; olu vavanyo lonyango lolunye uhlobo oluqhelekileyo lokuxilonga olusetyenziswa eNirogi Lanka nakwezinye iikliniki.
Ziziphi iindlela zonyango lwePellagra?
Ekubeni i-pellagra ibangelwa kukunqongophala kwe-niacin (iVitamin B3), unyango olusebenzayo kukugcwalisa izondlo ezilahlekileyo ngee-supplements ze-niacin. Uninzi lwabantu luqala ukuziva lungcono ngokukhawuleza xa unyango luqala. Nangona kunjalo, unokufuna unyango olongezelelweyo kwiimpawu zesibini ezifana nezilonda zesikhumba okanye zomlomo.
Okubaluleke kakhulu, ukuba i-pellagra yakho ibangelwa yimeko yesibini, kufuneka ufumane unyango olufanelekileyo kuloo ngxaki yezonyango engundoqo.
Ngaba kukho iziphumo ebezingalindelekanga kunyango?
Xa zithathwa njengoko ugqirha wakho ekuyalele, izongezo ze-niacin azifane zibangele iziphumo ebezingalindelekanga ezibalulekileyo. Iziphumo ezimbi zihlala zenzeka kuphela xa uthatha i-overdose, into engenakwenzeka kumntu onesifo sokungabikho komzimba. Ukuba ziyenzeka, zingabandakanya:
- Ukuhlanjwa kolusu.
- Ukurhawuzelela okanye ukurhawuzelela.
- Ukudumba kunye nokungagaywa kakuhle kokutya.
- Intloko ebuhlungu kunye nesiyezi.
Ungayithintela njani iPellagra?
Ukutya okunesondlo esifanelekileyo yeyona ndlela ilula yokuqinisekisa ukuba unesondlo esaneleyo. Ukuba uneendlela ezimbalwa zokutya, ukutya okutyebileyo kunye nezongezo zokutya kunokunceda. Umntu omdala osempilweni uhlala efuna malunga ne-15mg ye-niacin imihla ngemihla, edla ngokunikezelwa sisongezelelo sevithamini B-complex.
Ukutya okutyebileyo kwi-niacin kuquka:
- Isibindi senyama yenkomo
- Iibhithi
- Igwele leBrewer's
- Isonka esityebileyo kunye neenkozo
- Iintlanzi ezinamafutha, ezifana nesalmon kunye ne-tuna
- Iinati
- Iitapile
- Iinkuku
- Irayisi
- Imbewu yelanga
- Isosi yespaghetti
Ukuba unesifo esinganyangekiyo esiyandisa umngcipheko wakho we-pellagra, thetha nogqirha wakho malunga necebo lokuthintela ixesha elide, elinokubandakanya ukulungiswa kokutya kwakho, izongezo zokutya, okanye amayeza asetyenziswa rhoqo.
Kuthatha ixesha elingakanani ukuchacha kwiPellagra?
Wakuba uqalile ukuthatha izongezo ze-niacin, abantu abaninzi baphawula uphuculo kwiintsuku ezimbalwa. Iimpawu zesisu (ezifana norhudo) zihlala ziphela kuqala , zihlala kwiiveki zokuqala. Izilonda zesikhumba nomlomo zingathatha iiveki ezimbini ukuphola. Iimeko ezinzima zingathatha ixesha elide. Nceda uqaphele: umonakalo omkhulu wemithambo-luvo kunye ne-dementia ngamanye amaxesha zisenokungalungiseki.
Oogqirha bacebisa ukuba kugcinwe ukutya okunesondlo ukuthintela i-primary pellagra kwixesha elizayo. Ukunqongophala kwe-niacin kudla ngokudibana nezinye iingxaki zezakhamzimba, zonke ezi zinto zinokulungiswa ngokutya okunempilo.
Ukunyanga i-pellagra yesibini kunzima ngakumbi. Nangona izongezo zinceda, zisenokunganeli ukuba umzimba wakho awukwazi ukuyicola i-niacin ngokuchanekileyo. Kwezi meko, ukuchacha kuxhomekeke ngokupheleleyo ekuchongeni nasekunyangeni isifo esingundoqo, esinokuba yinkqubo yexesha elide.
Umyalezo Wokugqibela Wokuya Ekhaya
Nangona i-pellagra eyintloko itshatyalaliswa kakhulu kwiindawo eziphuhlileyo, isengumngcipheko kubantu abanokufikelela okuncinci kokutya. Kuluntu lwethu, ukunqongophala kwe-niacin yesibini kusaqhubeka kuyingxaki ngenxa yokusetyenziswa gwenxa kotywala kunye neemeko zempilo ezifihlakeleyo—ingakumbi ezo zichaphazela ukufunxwa kwezondlo. Ukuba ukrokrela ukuba unale mpawu, funa isikhokelo kwingcali yezonyango kwisibhedlele sakho sasekuhlaleni ngoko nangoko.
Eyona nto ibalulekileyo ekufuneka uyikhumbule kukuba nangona isondlo siqala ngokutya okutyayo, iinkqubo zangaphakathi zomzimba wakho zezona zimisela impilo-ntle yakho. Umzimba wakho uxhomekeke kwimisebenzi yangaphakathi enzima ukuze uhlale usempilweni. Ukuba ubona iimpawu ezikukhathazayo—ingakumbi imiba enxulumene nenkqubo yakho yokugaya ukutya—nceda ufune iingcebiso zonyango lobuchwephesha. Nokuba ukungabikho kweevithamini okuncinci kunokuchaphazela kakhulu impilo yakho. Ke ngoko, gxila ekutyeni ukutya okunesondlo, gcina indlela yokuphila esempilweni, kwaye udibane nogqirha ngokukhawuleza ukuba uneengxaki zempilo.
I-Pellagra, i-Niacin, iVithamin B3, Ukunqongophala kwesondlo, Iimeko zolusu, Urhudo, i-Dementia
