Ngaba ngamanye amaxesha uziva ngathi awunamandla, ngaba uhlala uneengxaki zesisu, ngamanye amaxesha unesifo sorhudo? Ayipheleli apho, kodwa ngaba ukwaneengxaki zesikhumba, iimpawu ezingaqhelekanga, njl.njl.? Ezi zinokuba ziimpawu zezifo ezahlukeneyo. Nangona kunjalo, namhlanje siza kuthetha ngemeko eyahlukileyo kancinci edla ngokudibana. Eso sisifo esibizwa ngokuba yi-pellagra .

Yintoni iPellagra?

Ngamafutshane, iPellagra sisifo esibangelwa kukunqongophala kwevithamini ebizwa ngokuba yi-niacin , ekwaziwa ngokuba yi -vitamin B3 . Olu luhlobo lokungondleki kakuhle. Ngokukodwa, kukunqongophala kwezakhamzimba. I-Niacin ibalulekile ekusebenzeni kweeseli emzimbeni wethu. Ngoko ke xa iphantsi, iziphumo zayo zibonakala njengeempawu emzimbeni wethu wonke, ngakumbi kwiindawo ezifana nolusu, umlomo, amathumbu, kunye nengqondo. Ukuba ayinyangwa kakuhle, iPellagra inokubangela umonakalo osisigxina kwinkqubo yemithambo-luvo kwaye ngamanye amaxesha ide ibulale. Ngoku usenokuba uzibuza ukuba wonke umntu uyayifumana na le nto. Uninzi lwexesha, umntu otya ukutya okunesondlo ufumana isixa esifunekayo se-niacin. Nangona kunjalo, i-pellagra ephambili - ebangelwa kukunqongophala kwe-niacin ekutyeni - iseyingxaki enkulu kwiindawo ezihlwempuzekileyo nezingenakutya. Nangona kunjalo, kumazwe aphuhlileyo, njengeSri Lanka, ukunqongophala kwe-niacin kudla ngokuba yinto yesibini kwezinye izizathu. Oko kukuthi, ezinye izifo okanye izinto ezithintela imizimba yethu ekufunxeni okanye ekusebenziseni i-niacin ngokufanelekileyo.

Yintoni iNiacin? Kutheni siyidinga?

Imizimba yethu isebenzisa i-niacin ukuguqula iikhalori ekutyeni esikutyayo zibe ngamandla. Cinga ngokutya esikutyayo njengepetroli enika amandla imoto yethu. Ukuze loo petroli isebenze, kufuneka icocwe ngokufanelekileyo. Yiloo nto eyenziwa yi-niacin. I-niacin esiyifumana ekutyeni esikutyayo ifunxwa kwizicubu zomzimba wethu ngamathumbu ethu amancinci. Apho, iba yi-coenzyme ebizwa ngokuba yiNicotinamide Adenine Dinucleotide (NAD) . Le NAD inceda ii-enzymes ezingaphezu kwama-400 ekusebenzeni komzimba wethu. Ngamafutshane, le NAD yeyona nto iphambili enceda iiseli zomzimba wethu ukuba zenze amandla (abizwa ngokuba yiAdenosine Triphosphate (ATP) ). Ukongeza, i-NAD inegalelo kwimisebenzi emininzi ebalulekileyo, njengokulungiswa kwe-DNA kunye nokunxibelelana phakathi kweeseli.

Ukungabikho kwe-niacin kuyichaphazela njani umzimba wam?

Ngenxa yokuba i-NAD yeyona nto iphambili ekuboneleleni ngamandla kwiiseli, xa iphelile, kuqala ichaphazela iinkqubo ezifuna amandla amaninzi okanye ezahlukana ngokukhawuleza. Oko kuthetha ulusu lwakho, ulwelo lwendlela yakho yokugaya ukutya (ukusuka emlonyeni wakho ukuya emathunjini akho), kunye nengqondo yakho. Oogqirha babiza iimpawu eziphambili ze-pellagra ngokuthi "3 Ds":Urhudo, i-dermatitis, kunye ne-dementia. Abanye bade bongeze "D" yesine: ukufa . Ukuba ayinyangwa iminyaka, inokubangela ukufa.

1. Urhudo (Isifo sohudo)

Urhudo lwenzeka xa ulwelo lwamathumbu akho (i-mucosa) lungavuseleli kakuhle. Cinga ngalo njengogqubuthelo olukhuselayo ngaphakathi kwamathumbu akho. Xa luphelile, amathumbu akho awakwazi ukugaya ukutya kakuhle okanye ukuzikhusela kwizifo okanye ekwenzakaleni. Oku kunokukhokelela ekuvuvukeni okuqhubekayo ukusuka emlonyeni wakho ukuya emathunjini akho. Oku kunokubangela iimpawu ezifana nentlungu yesisu, ukungagayi kakuhle kokutya, izilonda emlonyeni, kunye nolwimi olubomvu noludumbileyo .

2. I-Dermatitis (Ukulunywa lusu)

I-Pellagra luhlobo oluthile lwesifo solusu esichaphazela ulusu, ingakumbi ubuso, intamo, iingalo, imilenze, iintende, kunye neenyawo, ezivezwa lilanga. Xa iiseli zilahlekelwa ngamandla azo, iiseli zolusu ziba novelwano kakhulu ekukhanyeni kwelanga. Ekuqaleni, ulusu luba bomvu kwaye lubonakale ngathi lutshiswe lilanga. Kamva, iindawo ziba rhabaxa, zibe namaxolo, kwaye ngamanye amaxesha kuvele amabala amnyama (anombala omninzi) . Enye yeempawu zesi sifo yibhanti emnyama ejikeleze intamo. Ibizwa ngokuba yi "Casal's collar." Oku kubizwa ngegama likagqirha uDon Gaspar Casal, owaqala ukuchonga esi sifo phakathi kwabalimi baseSpain ngo-1735.

3. I-Dementia (Ukonakala kwengqondo kunye nemithambo-luvo)

I-Pellagra sisifo esichaphazela umzimba wonke. Ngenxa yokuba yonke iseli emzimbeni ilahlekelwa ngamandla afunekayo ukuze yenze umsebenzi wayo, ekugqibeleni ichaphazela ingqondo kunye nenkqubo yemithambo-luvo. Iimpawu zokuqala zisenokungabonakali kangako. Usenokuziva udiniwe, ungenamdla, kwaye ube nobunzima bokugxila . Okanye unokufumana iimpawu ezifana nokuxhalaba kunye nokudakumba . Ekuhambeni kwexesha, ezi mpawu zinokuqhubekela phambili ekudidekeni nasekukhohliseni . Kwiimeko ezinzima, i-dementia engapheliyo inokwenzeka, kunye neengxaki ze-neurological ezifana nobunzima bokulinganisela nokuhamba, ukuxhuzula kwemisipha, kunye nokungcangcazela .

Iphi iPellagra edla ngokubonwa kakhulu?

Ngokwembali, i-pellagra ifunyenwe kubantu abahlwempuzekileyo kwihlabathi liphela, kumazwe afana neYurophu, iAfrika, iAsia, kunye neMzantsi Melika. Idla ngokubonakala kubantu abatya ukutya okuncinci kakhulu. Ingakumbi kwabo babeneproteni encinci kwaye besitya umbona. Oku kungenxa yokuba i-niacin ifuna iproteni kunye nee-amino acids ukuze ifunxwe ngokufanelekileyo ngumzimba. Nangona umbona une-niacin, ukwimo "ebotshelelweyo" engenakufunxwa lula yimizimba yethu.

KuMbindi nakuMzantsi Merika, ngokwesikoXa kusenziwa iitortilla ngombona , umbona ufakwa emanzini elayimu ubusuku bonke. Le nkqubo ikhupha i-niacin embona kwaye iyenza ifunxwe lula. Yiyo loo nto i-pellagra inqabile kakhulu kwezo ndawo.

Kule mihla, iPellagra inqabile kakhulu kumazwe aseNtshona aphuhlileyo afana neMelika. Oku kungenxa yokuqinisa isonka nerayisi nge-niacin. Nangona kunjalo, iPellagra yokuqala isabonakala kwiindawo ezingaphuhlisiyo zehlabathi, ingakumbi phakathi kwabantu bezizwe ezitya umbona njengokutya okuphambili. Le meko isaqhubeka eIndiya, eTshayina, nakwezinye iindawo zaseAfrika. Nangona iPellagra yokuqala inqabile kumazwe afana neSri Lanka, kufuneka sikhathazeke ngePellagra ebangelwa zizizathu zesibini .

Zithini iimpawu zePellagra?

Nazi ezinye zeempawu eziqhelekileyo ze-pellagra:

• Urhudo oluhlala luhleli , ngamanye amaxesha luhamba negazi.
• Intlungu yesisu kunye nokungagaywa kakuhle kwesisu .
• Ukuphelelwa ngumdla wokutya , isicaphucaphu , kunye nokuhlanza .
• Ukurhawuzelela kwesikhumba okubangela ukurhawuzelelwa okanye iintlungu eluswini .
• Izilonda zomlomo kunye nolwimi olubomvu noludumbileyo.
• Ukudinwa kakhulu, ubuthathaka, kunye nokudinwa.
• Ukutshintsha kweemvakalelo, ukudakumba.
• Iimpawu zenkqubo yemithambo-luvo - umzekelo, ukungcangcazela kunye nokungaziva mnandi kwamalungu omzimba.
• Ukuphambana kwengqondo kunye ne-dementia.

Zithini izizathu zePellagra?

Isizathu esiphambili kukutya okuncinci kwi-niacin. Sifumana i-vitamin B3 (niacin) kwiintlobo ngeentlobo zokutya. Nangona kunjalo, abantu abanokukhetha ukutya okuncinci banokunqongophala kwezinye izondlo. I-Pellagra inokukhula ngenxa yezizathu zesibini . Oko kukuthi, ezinye iimeko zempilo ezithintela umzimba wakho ekufunxeni okanye ekusebenziseni i-niacin ngokufanelekileyo. Eminye imizekelo yile:

• Izifo zesisu ezibangela ukungafunxwa kokutya - umzekelo , iSifo seNtsholongwane yokuVuvukala (IBD) okanyeIsifo sokuqaqamba kwesibindi.
• Ingxaki yokusebenzisa utywala: Ukusela utywala kakhulu kunokonakalisa amalungu omzimba anjengesibindi kwaye kunciphise amandla omzimba okufunxa izondlo ezifana ne-niacin. Oku kunokukhokelela ekungondlekini kakuhle.
• Utyando lwesisu: Emva kotyando oluthile lokutyeba kakhulu, i-mucosa yamathumbu inokonakala, nto leyo ekhokelela ekuswelekeni kwezakhamzimba ezahlukeneyo, kuquka ne-niacin.
• I-anemia yokungabikho kwe-iron: Umzimba udinga i-iron ukuze uguqule kwaye usebenzise i-niacin.
• Isifo sikaHartnup: Esi sisifo esibangelwa lufuzo. Sithintela umzimba ekufunxeni ii-amino acids. Ezi amino acids zibalulekile ekwenzeni iivithamini.
• Isifo seCarcinoid: Kule meko, ukuveliswa kwe-niacin ziiseli zomhlaza kuyancitshiswa.
• Amayeza athile: Amanye amayeza, ingakumbi amayeza okulwa noxinzelelo lwegazi kunye namayeza e-chemotherapy, anokuphazamisana ne-metabolism ye-niacin.
• Usulelo lwe-HIV: Usulelo lwe-HIV lubangela ukwehla kwamanqanaba e-niacin emzimbeni.

Ifunyanwa njani iPellagra?

Xa ubona ugqirha, uza kukuxilonga aze akubuze ngeempawu zakho, imbali yakho yezonyango, kunye nokutya kwakho. Ukuba kukho i-pellagra erhanelwayo, uvavanyo lomchamo lungenziwa ukuqinisekisa ukuxilongwa. Amanqanaba eekhemikhali ezithile kumchamo wakho anokuxelela ukuba unayo na i-niacin eyaneleyo emzimbeni wakho. Ugqirha wakho unokukunika izongezo ze-niacin ukuze abone ukuba ziyanceda na. Leyo yindlela enye yokufumanisa isifo.

Ziziphi iindlela zonyango lwePellagra?

I-Pellagra ibangelwa kukunqongophala kwe-niacin, okanye i-vitamin B3. Ngoko ke, unyango olungcono ngayo kukugcwalisa umzimba ngesondlo esingekhoyo. Oko kuthetha ukunika izongezo ze-niacin. Uninzi lwabantu luqala ukuchacha ngokukhawuleza xa beqala ukuzithatha. Nangona kunjalo, unyango olongezelelweyo lunokufuneka kwizinto ezifana nezilonda zesikhumba kunye nezilonda zomlomo.

Eyona nto ibalulekileyo kukuba ukuba une-pellagra ngenxa yesizathu sesibini, oko kukuthi, esinye isifo, kufuneka unyange ngokufanelekileyo eso sifo singundoqo.

Ngaba kukho naziphi na iziphumo ebezingalindelekanga kunyango?

Ukuba uthatha amayeza njengoko ugqirha wakho ekuyalele, izongezo ze-niacin azidli ngokubangela naziphi na iziphumo ebezingalindelekanga. Nangona kunjalo, ukuba uthatha i-overdose, ezinye iziphumo ebezingalindelekanga zinokubakho. Nangona kunjalo, umntu onesiphene emzimbeni wakhe akayi kuthatha i-overdose ngokulula. Ukuba oko kuyenzeka, ezi zinto zilandelayo zinokwenzeka:

• Ukuhlanjwa kolusu.
• Ukurhawuzelela kunye nerhashalala ye-eczema.
• Ukudumba kunye nokungagaywa kakuhle kokutya.
• Intloko ebuhlungu kunye nesiyezi.

Ungayithintela njani iPellagra?

Ukutya ukutya okunesondlo esifanelekileyo yeyona ndlela ilula yokuhlala usempilweni. Ukuba ukhetho lokutya luncinci, ukutya okunesondlo kunye nezongezo zokutya kunokunceda. Malunga ne-15 milligrams ye-niacin ngosuku yanele umntu omdala osempilweni. Eli nani lidla ngokufumaneka kwi-B-complex vitamin supplement. Ezinye zokutya ezityebileyo kwi-niacin ziquka:

• Isibindi senyama yenkomo
• I-Beetroot (iiBeetroot)
• Igwele leBrewer's
• Isonka esityebileyo kunye neenkozo
• Iintlanzi ezinamafutha, ezifana nesalmon kunye ne-tuna
• Iinati
• Amazambane
• Iinkuku
• Irayisi
• Imbewu yelanga
• Isosi yespaghetti

Ukuba unesifo esinganyangekiyo esikwenza ube nethuba lokufumana i-pellagra, thetha nogqirha wakho malunga neendlela zokuyithintela ekuhambeni kwexesha. Oku kungabandakanya ukwenza utshintsho kwindlela otya ngayo, izongezo zokutya, okanye amayeza owasebenzisayo.

Kuthatha ixesha elingakanani ukuchacha kwiPellagra?

Xa uqala ukuthatha izongezo ze-niacin, uninzi lwabantu luqala ukuziva ngcono kwiintsuku ezimbalwa. Iimpawu zokugaya ukutya (ezifana norhudo) zihlala ziphucuka kuqala , zihlala kwiveki yokuqala. Izilonda zesikhumba nomlomo zingathatha iiveki ezimbini ukuphola. Ezinye iimeko ezinzima zingathatha ixesha elide. Ukonakala okukhulu kwemithambo-luvo kunye ne-dementia kusenokungaphindi kuguqulwe. Ukuthintela i-pellagra yokuqala, oogqirha bacebisa ukugcina ukutya okunesondlo. Ukunqongophala kwe-Niacin kudla ngokuhamba kunye nezinye iziphene zezakhamzimba. Zonke ezi zinto zinokulungiswa ngokutya okulungileyo. Ukunyanga i-pellagra yesibini kunokuba nzima ngakumbi. Ngelixa izongezo zinokunceda, ukuba umzimba awukwazi ukuyicola i-niacin ngokufanelekileyo, olo ncedo lusenokunganeli. Kwiimeko ezinjalo, ukuchacha kuxhomekeke ekuchongeni nasekunyangeni imeko engundoqo ebangele i-pellagra. Oku kunokuba yinkqubo ende, kuxhomekeke kwisifo.

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Nangona i-primary pellagra isusiwe kakhulu kumazwe aphuhlileyo, isakho phakathi kwabantu abahlwempuzekileyo abanokutya okulinganiselweyo. Kumazwe afana nelethu, ukunqongophala kwe-niacin yesibini kusengumngcipheko ngenxa yokusetyenziswa kotywala kunye neemeko ezithile zonyango (ingakumbi ezo ziphazamisa ukufunxwa kwezondlo).

Eyona nto ibalulekileyo kukukhumbula ukuba nangona izondlo ziqala ngokutya, ziphelela ngaphakathi emzimbeni.Izinto ezininzi emzimbeni wakho kufuneka zisebenze kakuhle. Ukuba uneempawu ezibonisa ukuba kukho into engalunganga, ingakumbi ukuba uneengxaki kwinkqubo yakho yokugaya ukutya, qiniseka ukuba ufuna ingcebiso kagqirha. Nokuba uswele iivithamini ezincinci kunokuba nefuthe elikhulu kwimpilo yakho. Ngoko ke, yitya ukutya okunesondlo, phila ubomi obusempilweni, kwaye ubone ugqirha ngokukhawuleza ukuba uneengxaki.

I-Pellagra, i-niacin, i-vitamin B3, ukunqongophala kokutya, izifo zolusu, urhudo, i-dementia