Ngaba wakha wacinga ngokubaluleka kokuqina kwegazi emizimbeni yethu? Kungenxa yale nkqubo apho ukopha kuyeka xa kukho ukwenzakala okuncinci. Kodwa, kuthekani ukuba igazi liyaqina ngaphakathi emzimbeni ngaphandle kwesizathu? Oko kunokuba yingozi kancinci. Namhlanje siza kuthetha ngemeko enjalo. Oko kukunqongophala kweProteni S, okanye `(Ukunqongophala kweProteni S)`.
Ngamafutshane, yintoni ukunqongophala kweProteni S?
Cinga ngenkqubo yokuqina kwegazi emzimbeni wethu njengepolisa lendlela elilawula ukuxinana kwezithuthi. Kufuneka kubekho umntu oza kulawula yonke into. Ngokufanayo, enye yezona proteni zibalulekileyo ezilawula ukuqina kwegazi emzimbeni wethu yiProtein S.
Ngoku, ukunqongophala kweProtein S kuthetha ukuba asinazo izinto ezininzi ezibizwa ngokuba "yipolisa" okanye iProtein S emzimbeni wethu kunokuba sizidinga. Kwenzeka ntoni ke ngoko? Ekubeni kungekho mntu ulawula inkqubo yokujiya kwegazi, iba yinto esebenzayo kakhulu kwaye amahlwili egazi aqala ukwakheka ngokungeyomfuneko.
Amahlwili egazi ayenzeka ngolu hlobo adla ngokwenzeka kwimithambo enzulu yemilenze. Oku sikubiza ngokuba yi-deep vein thrombosis (DVT) . Ngamanye amaxesha eli hlwili legazi linokuphuma apho lize lihambe negazi liye emiphungeni lize libhajwe. Le yimeko eyingozi nangakumbi. Siyibiza ngokuba yi-pulmonary embolism (PE) . Amaxesha amaninzi, la mahlwili egazi anokwenzeka nakwimithambo yengqondo okanye esiswini.
Kodwa kukho into ebalulekileyo ekufuneka uyikhumbule apha. Oko kukuthi, ayinguye wonke umntu onesifo sokunqongophala kweProteni S ofumana amahlwili egazi. Uninzi lwabantu luphila ubomi obuqhelekileyo ngaphandle kweengxaki.
Ixhaphake kangakanani le meko? Kwaye nini apho ingozi iphezulu khona?
Ukunqongophala kweProteni S yimeko engaqhelekanga. Uninzi lwexesha, lufuzo, oko kuthetha ukuba lufuzo. Kodwa lunokubangelwa zizinto ezithile zangaphandle.
Ukuba unale meko, kukho iimeko ezithile apho unokuba sengozini enkulu yokuba namahlwili egazi. Makhe sijonge ukuba zeziphi ezo meko.
| Ithuba lokunyusa umngcipheko | Ingcaciso elula |
|---|---|
| Ukukhulelwa | Ngexesha lokukhulelwa, utshintsho lwehomoni emzimbeni kunye notshintsho kwindlela igazi elihamba ngayo emzimbeni luyandisa utyekelo lwendalo lokuba igazi lijiye. |
| Ukwaluphala | Umngcipheko uyanda njengoko ukusebenza komzimba kuncipha kwaye kuvela nezinye izifo. |
| Amanye amayeza | Ukusela iipilisi zokulawula ukukhulelwa okanye olunye unyango lweehomoni, ngakumbi, kwandisa umngcipheko. |
| Ndisenza utyando | Emva kotyando olukhulu, usenokulala ebhedini ixesha elithile, nto leyo enokuphazamisa ukujikeleza kwegazi kwaye ibangele ukuba igazi liqhekeke. |
| Ukonzakala | Emva kwengozi enkulu, ukuthambekela komzimba ekujiyeni kunokwanda njengempendulo. |
| Ukuhlala kwindawo efanayo ixesha elide | Umzekelo, izinto ezinje ngokuhamba ngenqwelo moya ixesha elide okanye ukugula okubangelwa kukungalali ebhedini zinokunciphisa ukuhamba kwegazi emilenzeni kwaye zibangele i-DVT. |
Zithini iimpawu zale meko?
Ixesha elininzi, umntu onesifo seProteni S akayi kuba nazimpawu de kube kuphume ihlwili legazi. Ukuba kuphuma ihlwili legazi, iimpawu ziya kwahluka ngokuxhomekeke kwindawo elivela kuyo.
- Ukuba uphuma ihlwili legazi (DVT) emlenzeni wakho:
- Ukudumba komlenze omnye, ingakumbi indawo yempundu.
- Ukuva intlungu okanye ukuqina komlenze.
- Ubomvu okanye ukuziva ufudumele eluswini lomlenze.
- Ukuba uphuma igazi elijiyileyo (PE) emiphungeni (le yingxamiseko):
- Ubunzima bokuphefumla ngequbuliso.
- Intlungu esifubeni, ingakumbi xa uphefumla nzulu.
- Ukuphefumla ngokukhawuleza kunye nokubetha kwentliziyo okunyukayo ngaphandle kwesizathu.
- Ukudinwa okanye ukuphelelwa zingqondo.
- Ukuphuma kwencindi enegazi.
- Ngexesha lokukhulelwa: Ukuphuma kwesisu okanye ezinye iingxaki zinokwenzeka.
- Kubantwana abancinci (kwiimeko ezinzima kakhulu): Iimeko ezifana nestroke zinokwenzeka.
Kutheni le nto kukho ukunqongophala kweProteni S?
Zimbini izizathu eziphambili zoku: Esinye sizuzwe njengelifa (ilifa) kwaye esinye sizuzwe (ifunyenwe) .
1. Izizathu ezibangelwa lilifa
Le yeyona ixhaphakileyo. Ukuveliswa kweProtein S emzimbeni wethu kulawulwa yi-gene ebizwa ngokuba yi -PROS1 . Ukuba kukho utshintsho okanye utshintsho kule gene, ukuveliswa kweProtein S kuyaphazamiseka.
- Ukuba uzuze esi jini siguqukileyo kumzali omnye kuphela , uya kuba nokusilela okuncinci kweProteni S.
- Ukuba uzuze esi sifuzo kubazali bobabini , uya kuba nohlobo olubi kakhulu lwesi sifo. Oku kunqabile kakhulu.
2. Izizathu zangaphandle
Ezinye iimeko zonyango okanye iimeko zinokubangela amanqanaba aphantsi eProtein S emzimbeni. Oku kuqheleke kakhulu kunelifa.
| Izizathu ezinokwenzeka zangaphandle |
|---|
| Isifo sesibindi |
| Isifo sezintso kunye nesifo se-nephrotic |
| I-Chemotherapy yomhlaza |
| Iintsholongwane ezithile |
| Ukunqongophala kweVitamin K |
| Ukusetyenziswa kweepilisi zokukhulelwa kunye nokulawula ukuzalwa |
Uyifumana njani le nto, Gqirha?
Ugqirha wakho usenokuba uyakrokrela oku, ingakumbi kwiimeko ezifana nezi:
- Ukuba kukho umntu kusapho lwakho onembali yokuqhekeka kwegazi rhoqo (i-Venous Thromboembolism).
- Ukuba unegazi eliphindaphindayo .
- Ukuba ukhe waba nehlwili legazi ngaphambi kokuba ufikelele kwiminyaka engama-50, ngaphandle kokuba kufunyanwe isizathu esithile .
- Ukuba igazi liqhekekile kwiindawo ezingaqhelekanga apho igazi lingaqhekeki khona (njengengqondo, amathumbu, isibindi) .
Ukuba kuvela olu hlobo lokurhanelwa, ugqirha uya kwenza oku kulandelayo ukuqinisekisa ukuxilongwa:
1. Uvavanyo lwegazi: Igazi lakho liza kuvavanywa amanqanaba eProtheni S kunye nezinye izinto ezinxulumene nokugabha kwegazi.
2. Uvavanyo lomzimba: Kuya kwenziwa uvavanyo olupheleleyo lomzimba ukujonga ezinye iingxaki.
3. Imbali yakho yezonyango: Siza kukubuza ngeemeko zakho zempilo kunye nezosapho lwakho.
Iphathwa njani?
Indlela yonyango ixhomekeke ekubeni unayo na ihlwili legazi okanye akunjalo.
Eyona nto ibalulekileyo kukuba, nokuba uvavanyo lwegazi luqinisekisa ukuba unesiphene seProtein S, ukuba awukaze ube nehlwili legazi, kusenokwenzeka ukuba akuyi kufuneka uqhubeke nokusela amayeza.
Nangona kunjalo, ukuba sele une-blood clot (DVT okanye PE), ugqirha wakho uza kukuqalisa ngee-anticoagulants . Ezi zisebenza ngokuthintela ukwakheka kwamahlwili egazi amatsha nokuthintela amahlwili akhoyo ukuba abe makhulu. Iindidi eziqhelekileyo zamayeza asetyenziswayo zezi:
- I-Heparin
- I-Warfarin
- I-Rivaroxaban
- I-Apixaban
- I-Dabigatran
Nantsi into omele uyazi: Ukuba ugqirha wakho ugqiba ekubeni akunike iyeza elibizwa ngokuba yi-"Warfarin," kuya kufuneka akunike iyeza elibizwa ngokuba yi-"Heparin" (ngokufuthi njengenaliti) kwiintsuku ezimbalwa ngaphambi koko. Ukuba awukwenzi oko, ngamanye amaxesha unokufumana ingxaki ebizwa ngokuba yi-blood clots eluswini nakwizicubu ezithambileyo. Kodwa le ngxaki ayifumaneki kwamanye amayeza amatsha.
Unyango lwakho lunokuhlala iinyanga ezimbalwa ukuya kubomi bonke, kuxhomekeke ekubeni igazi lakho lenzeke nini kunye nezinye izinto ezinobungozi.
Wenza ntoni kubantu abangenalo ihlwili legazi, kodwa benengxaki yokunqongophala kwegazi?
Injongo kagqirha kubantu abanjalo kukuncedisa ekuthinteleni ukwakheka kwamahlwili egazi.
- Ungacetyiswa ukuba ungasebenzisi amayeza anyusa ukujiya kwegazi, njengeepilisi zokulawula ukukhulelwa.
- Ukuba utyando, ukhulelwe, okanye ulele ebhedini okwethutyana ngenxa yengozi , ungacetyiswa ukuba usebenzise izithibi zegazi okwethutyana ngelo xesha kuphela.
Ndingazinyamekela njani?
- Ukuba usebenzisa iWarfarin: Kuya kufuneka uhlolwe i-INR yakho rhoqo .Kuya kufuneka uhlolwe igazi. Oku kuya kujonga ukuba idosi ye-`(Warfarin)` oyinikwayo ichanekile na. Kuba idosi yale yeza inokufuneka itshintshwe ngamanye amaxesha.
- Ukuba uthatha amayeza okunciphisa igazi: Lumka ukopha. Lumka xa usebenzisa izinto ezibukhali ezifana neemela. Kungcono ukusebenzisa ibhrashi yamazinyo ethambileyo kunye nerazor yombane.
- Qaphela iimpawu ze-DVT kunye ne-PE: Ufanele ukwazi ukubona iimpawu ezinje ngokudumba kwemilenze, iintlungu zesifuba, kunye nokuphefumla kancinci ukuba ziyavela.
Ndifanele ndimbone nini ugqirha ndize ndiye kwi-ETU?
### Fowunela ugqirha wakho ngoko nangoko kwezi meko:
- Ukuba uyawa okanye ufumana enye ingozi ngelixa uthatha amayeza okunciphisa igazi.
- Ukuba kukho ukopha okungaqhelekanga (umz. ukopha empumlweni, igazi kumchamo okanye kwindle).
- Ukuba ukrokrela ukuba une-DVT (igazi eliqhekekileyo emlenzeni) .
### Ukuba unale mpawu, yiya kwiSebe leeNgxamiseko (ETU) ngoko nangoko:
- Ukuba uthatha amayeza okunciphisa igazi kwaye uhlanza igazi okanye ukhohlela igazi .
- Ukuba ubetheka entloko okanye ngequbuliso uqalwa yintloko ebuhlungu kakhulu .
- Ukuba kukho ukopha oko akunakuyekiswa .
- Ukuba ucinga ukuba uneempawu ze-PE (igazi eliqhekekileyo emiphungeni) (ukuphelelwa ngumphefumlo ngequbuliso, iintlungu zesifuba, ukubetha kwentliziyo ngokukhawuleza, isiyezi).
Umyalezo Wokuya Ekhaya
- Ukunqongophala kweProteni S yimeko ebangela ukuba igazi lijiye. Oku kudla ngokuzuzwa njengelifa.
- Asinguye wonke umntu onesi sifo ofumana amahlwili egazi. Uninzi lwabantu alunazo naziphi na iingxaki.
- Hlala uqaphela iimpawu ezinje ngokudumba kwemilenze, iintlungu (DVT) kunye nokuphefumla okukhawulezileyo kunye nentlungu yesifuba (PE).
- Ukuba unikwe amayeza okunciphisa igazi, thatha kanye njengoko ugqirha wakho ekuxelele, ngedosi efanelekileyo, nangexesha elifanelekileyo. Ungaze uyeke ukuwasebenzisa la mayeza.
- Ukuba kuvela naziphi na iimpawu eziyingozi ngequbuliso, ungoyiki ukufuna ingcebiso yezonyango ngoko nangoko okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU).
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