Ngaba uneempawu zesifo sikaParkinson ezifana nokungcangcazela nokuqina? Ukuba kunjalo, ugqirha wakho usenokuba ukunike iyeza elibizwa ngokuba yiSelegiline kunye neLevodopa. Eli liyeza elihlala linikwa. Ngoko ke, kweli nqaku, siza kuthetha ngokuba yintoni iSelegiline, yintoni kanye kanye eyenzayo, kunye nento ekufuneka uyilumkele ngakumbi xa usebenzisa eli yeza.
Yintoni iSelegiline? Yintoni eyenzayo?
Ngamafutshane, iSelegiline liyeza elisetyenziselwa ukulawula iimpawu zesifo sikaParkinson. Likwiqela lamayeza abizwa ngokuba yiMAOIs. Iingqondo zethu ziqulethe ikhemikhali ebizwa ngokuba yidopamine . Oku kunceda imizimba yethu ishukume kwaye ilungelelanise kakuhle. Kubantu abanesifo sikaParkinson, inqanaba lale dopamine engqondweni liyehla.
I-Selegiline isebenza ngokunyusa ubungakanani be-dopamine engqondweni. Oku kunokunceda ekunciphiseni iimpawu ezifana nokuqina kunye nokungcangcazela, okukuvumela ukuba wenze imisebenzi yemihla ngemihla ngokulula.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Kubaluleke kakhulu ukuba ugqirha wakho ayazi kakuhle imeko yakho yempilo ngaphambi kokuba akunike iSelegiline. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho ngazo.
- Ukuba une-high blood pressure.
- Ukuba unesifo sesibindi.
- Ukuba uxinzelelo lwegazi luphantsi.
- Ukuba une-narcolepsy, imeko ebangela ukuba ulale ngequbuliso emini.
- Ukuba une-sleep apnea.
- Ukuba une-allergy kwi-selegiline okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe okanye uzama ukukhulelwa.
- Ukuba ungumama oncancisayo.
Ndingayisebenzisa njani kanye kanye le yeza?
Eli yeza lifanele lithathwe ngomlomo kunye neglasi yamanzi. Kubaluleke kakhulu ukulithatha eli yeza ngexesha elifanelekileyo, ngedosi efanelekileyo, njengoko ugqirha wakho ekuyalele. Musa ukunyusa, ukunciphisa, okanye ukuyeka idosi ngokuthanda kwakho.
Kubaluleke kakhulu: Musa ukuyeka ukuthatha eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela impendulo enzulu. Ukuba uyeka, kufuneka wenze njalo ngokunciphisa kancinci umthamo njengoko ugqirha wakho ekuxelela.
Yintoni omawuyenze ukuba usebenzisa amayeza ngokugqithisileyo?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, musa ukoyika. Ngoko nangokoFowunela iZiko loLwazi ngeTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo. Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (i-ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndilibele ukusela amayeza am?
Ukuba ulibele ukuthatha idosi uze ukhumbule emva koko, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba sele kusondele ixesha lokuthatha idosi yakho elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe idosi ephindwe kabini.
Izinto ezingafanele zisetyenziswe ngeSelegiline (Interactions)
Le yinto ekufuneka uyilumkele kakhulu. I-Selegiline sisiyobisi esinokudibana nezinye amayeza nokutya.
Iingxaki ngamayeza
Ukuba usebenzisa la mayeza alandelayo, musa ukuthatha iSelegiline konke konke .
- I-Atomoxetine, i-Cyclobenzaprine, i-Dextromethorphan (equlethwe kwiisiraphu zokukhwehlela)
- Amanye amayeza e-MAOI afana neMarplan, iNardil, iParnate
- Izithomalalisi zentlungu ezifana neMeperidine, iMethadone, neTramadol
- Amanye amayeza aqulethe iSelegiline, njenge-Emsam
- I-Rasagiline, i-Safinamide (ikwaliyeza lesifo sikaParkinson)
- Amayeza okuvuselela iingxaki zokuqwalasela
- I-St. John's Wort (imveliso yezityalo)
- I-Viloxazine
Ukongeza, amayeza ezifo zengqondo ezifana nokudakumba kunye noxinzelelo, ezinye izinto ezinciphisa ukuxinana (i-phenylephrine, i-pseudoephedrine), kunye namayeza okunciphisa umzimba nazo zinokuchaphazela oku.
Ngoko ke, kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini, iimveliso zezityalo, kunye neentlungu) .
Iingxaki zokutya (Ukusebenzisana kweTyramine)
Le yeyona nto ibalulekileyo ekufuneka uyiqwalasele xa usebenzisa eli yeza. Akuyonto ilungileyo ukutya ukutya okune- tyramine eninzi ngelixa usebenzisa iSelegiline. Ukwenza njalo kunokubangela ukuba uxinzelelo lwakho lwegazi lunyuke ngokukhawuleza ngequbuliso, kubangele iintloko ezibuhlungu, kwaye kubangele ukubetha kwentliziyo okungaqhelekanga.
| Ukutya ekufuneka ukuphephe xa usebenzisa iSelegiline ngenxa yokuba ineTyramine eninzi | |
|---|---|
| Uhlobo lokutya | Imizekelo |
| Iitshizi ezindala | Iitshizi ezifana neCheddar, itshizi eluhlaza okwesibhakabhaka, iGorgonzola, kunye neParmesan. |
| Inyama/intlanzi ecutshungulweyo netshayiweyo | Iisoseji, isalami, ipepperoni, intlanzi eyomisiweyo, iijalapenos. |
| Iziselo ezinxilisayo | Ibhiya (ingakumbi ibhiya eyosiweyo), iwayini ebomvu, isherry. |
| Iimveliso zesoya | Isosi yesoya, isuphu yemiso, itofu. |
| Okunye | Iiavokhado, iibhanana, iirayisi, iziqhamo ezivuthiweyo. |
Cela ugqirha wakho uluhlu olupheleleyo lwazo.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa iyeza
- Ukozela kunye nesiyezi: Eli yeza linokukwenza uzive ulele okanye unesizungu. Ngoko ke, musa ukuqhuba okanye ukusebenzisa oomatshini ude wazi ukuba eli yeza likuchaphazela njani. Lumka xa uvuka kwindawo ohleli kuyo okanye omiyo ngequbuliso.
- Utywala: Kuphephe ukusela utywala. Bunokuphazamisa ukusebenza kakuhle kwamayeza.
- Umlomo owomileyo: Ukuba unomlomo owomileyo, ungafumana isiqabu ngokuhlafuna itshungama engenaswekile nokusela amanzi amaninzi.
- Ezinye izifo: Buza ugqirha wakho ngaphambi kokuba uzithathele amayeza kwizinto ezinje ngokukhwehlela, umkhuhlane kunye nomkhuhlane.
- Isifo seswekile: Ukuba unesifo seswekile, eli yeza lisenokuchaphazela amanqanaba eswekile egazini lakho. Ngoko ke thetha nogqirha wakho ngaphambi kokuba utshintshe umlinganiselo okanye indlela otya ngayo amayeza eswekile.
- Utshintsho lolusu: Qaphela naluphi na utshintsho kulusu lwakho okanye ukubonakala kwamabala amatsha ngelixa usebenzisa eli yeza. Jonga ulusu lwakho rhoqo. Ukuba ubona naluphi na utshintsho olunjalo, xelela ugqirha wakho ngoko nangoko.
Iziphumo ebezingalindelekanga ezinokwenzeka ngeli yeza
| Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko | |
|---|---|
| Ii-aleji | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi. |
| Uxinzelelo lwegazi oluphezulu kakhulu | Ukuqala ngequbuliso kwentloko ebuhlungu, isicaphucaphu, ukuhlanza, intamo eqinileyo, kunye nokubetha kwentliziyo ngokukhawuleza. |
| Utshintsho lwengqondo kunye nokuziphatha | Ixhala, ukuphazamiseka, ukubona izinto ezingekhoyo, iingcinga zokuzibulala, ukudakumba okukhulu. |
| Iintshukumo ezingalawulekiyo | Iintshukumo ezintsha okanye ezandileyo ezingalawulekiyo zobuso, umlomo, okanye umzimba ongasentla. |
| Ezinye iimpawu ezinzulu | Iindlela ezingaqhelekanga zokuziphatha ngokungxama ezifana nokulala ngequbuliso ngelixa usenza imisebenzi yemihla ngemihla, isiyezi kunye nokungaboni kakuhle, uxinzelelo lwegazi oluphantsi, ukungcakaza, kunye nokutya kakhulu. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| |
Umyalezo Wokuya Ekhaya
- I-Selegiline liyeza elinceda ukulawula iimpawu zeParkinson kwaye lonyusa amanqanaba e-dopamine engqondweni.
- Musa ukuyeka ukuthatha eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho.
- Kuphephe ngokupheleleyo ukutya okune-tyramine eninzi (njengetshizi ecociweyo, inyama ecociweyo, kunye newayini ebomvu) ngelixa usebenzisa eli yeza.
- Yazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinje ngentloko ebuhlungu kakhulu, ukunyuka ngesiquphe koxinzelelo lwegazi, okanye utshintsho lwengqondo, funa ingcebiso kagqirha ngoko nangoko.
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