Umntu ophila nesifo sikaParkinson ngamanye amaxesha uba nexesha 'lokungasebenzi' apho umzimba ngequbuliso uphelelwa bubomi, amalungu aphulukane namandla awo, aze angakwazi ukuhamba kakuhle. Ngala maxesha, baziva bengenakukwazi ukwenza nemisebenzi yemihla ngemihla. Ngoko ke, namhlanje sithetha ngamayeza akhethekileyo anceda ukulawula ngokukhawuleza eli xesha 'lokungasebenzi' ngequbuliso.
Lithini eli yeza libizwa ngokuba yiApomorphine?
Ngamafutshane, i-Apomorphine liyeza elisetyenziselwa ukunyanga izigaba 'zokuyeka' zesifo sikaParkinson, eziziintshukumo ezinzima nezingxamisekileyo. Liza njengefilimu encinci enyibilikayo phantsi kolwimi. I-KYNMOBI ligama lophawu oludumileyo lwale chiza.
Khawuthelekelele, ubuchopho bethu bunekhemikhali ekhethekileyo ebizwa ngokuba yi-dopamine. Yile nto isinceda silawule iintshukumo zomzimba wethu kunye nokulungelelana kwazo. Inqanaba lale dopamine engqondweni yomntu onesifo sikaParkinson liyehla. I-Apomorphine yonyusa ubungakanani be-dopamine engqondweni, inciphisa ngokukhawuleza iimpawu ezifana nokuqina, ukungcangcazela, kunye nokuhamba kancinci.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokusebenzisa eli yeza
Kubaluleke kakhulu ukuba ugqirha wakho azi kakuhle imeko yakho yempilo ngaphambi kokuba akunike eli yeza. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho ngazo.
| Jonga ukuba unazo na ezi meko |
|---|
| Ukuba ulala ngequbuliso ngelixa usenza imisebenzi yemihla ngemihla (umz., ukuthetha, ukutya) |
| Ukuba unengxaki yokulawula izihlunu zakho |
| Ukuba unesifo sentliziyo, ukungahambelani kwesingqisho sentliziyo, okanye utshintsho kwisingqisho |
| Ukuba uxinzelelo lwegazi luphantsi |
| Ukuba unesifo sezintso okanye sesibindi |
| Ukuba uneengxaki zokuphefumla ezifana nesifo semiphunga okanye i-asthma |
| Ukuba ukhe waba nesifo sohlangothi |
| Ukuba unayo nayiphi na uhlobo lwesifo sengqondo |
| Ukuba une-sleep apnea |
| Ukuba usela rhoqo |
| Ukuba une-allergies kwi-apomorphine, i-sulfites, okanye nayiphi na enye iyeza, ukutya, okanye umbala |
| Ukuba ukhulelwe okanye unethemba lokukhulelwa |
| Ukuba ungumama oncancisayo |
Ndingayisebenzisa njani kanye kanye le yeza?
Kulula kakhulu ukuyisebenzisa, kodwa kufuneka ulandele imiyalelo ngokuchanekileyo.
1. Sebenzisa eli yeza kuphela xa imeko 'yokungasasebenzi' iqala .
2. Izandla zakho mazibe zomile ngokupheleleyo ngaphambi kokuba uphathe iyeza.
3. Yaphula isikhwama sefoyile esivaliweyo esinamayeza uze ususe ngononophelo ifilimu enyibilikayo.
4. Beka loo filimu phantsi kolwimi lwakho .
5. Yiyeke inyibilike yodwa. Musa ukuyisika, ukuyityumza, okanye ukuyihlafuna.
6. Musa ukusebenzisa ngaphezu komlinganiselo omiselwe ngugqirha.
Okubaluleke kakhulu, ungayeki ukusebenzisa eli yeza ngaphandle kokuba ugqirha wakho ekuxelele ukuba uyeke. Ukuliyeka ngequbuliso kunokwenza imeko yakho ibe mandundu kwaye kubangele iziphumo ebezingalindelekanga ezibi kakhulu.
Yintoni omawuyenze ukuba ugqithisile ?
Ukuba ucinga ukuba uthathe eli yeza kakhulu, qhagamshelana ngokukhawuleza neZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo, okanye uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane. Eli yeza limiselwe wena kuphela. Ungaze ulinike abanye.
Kuthekani ukuba ndiphoswa yidosi?
Eli asiloyeza elifuna ukuselwa amaxesha amaninzi ngemini. Lisetyenziswa kuphela xa unexesha 'lokungasebenzi'. Ngoko ke ingcamango yokungafumani idosi ayisebenzi apha. Nangona kunjalo, ukuba awufumani kuphumla kwiimpawu zakho emva kokusebenzisa ifilimu enye ngexesha 'lokungasebenzi', musa ukusebenzisa enye ifilimu ngelo xesha. Thetha nogqirha wakho ngale nto.
Amanye amayeza anokusebenza kunye nale mayeza
I-Apomorphine liyeza elinokusebenzisana namanye amayeza. Ngoko ke, kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu).
| Musa ukuyithatha i-Apomorphine nala mayeza. | |
|---|---|
| Amanye amayeza okunyanga isicaphucaphu/ukuhlanza (umz., i-dolasetron, i-granisetron, i-ondansetron, i-palonosetron) | |
| ICisapride, iDronedarone, iPimozide, iThioridazine | |
| Lumka kakhulu xa usebenzisa i-Apomorphine kunye nala mayeza. | |
| Utywala | |
| Amayeza okunyanga ixhala okanye ukulala | |
| Amayeza oxinzelelo lwegazi, isifo sentliziyo, kunye neengxaki zesingqisho sentliziyo | |
| Amayeza eentlungu ezibangelwa yiziyobisi | |
| I-Nitroglycerin | |
| IHaloperidol, iMetoclopramide, iiPhenothiazines (umz. i-chlorpromazine, i-prochlorperazine) | |
| Amanye amayeza achaphazela isigqi sentliziyo (andisa ixesha le-QT) |
Olu luhlu aluphelelanga, ngoko qiniseka ukuba uxelela ugqirha wakho ngazo zonke amayeza owasebenzisayo.
Izinto ekufuneka uzikhumbule xa usebenzisa eli yeza
- Ukozela kunye nesiyezi: Ungaziva ulele okanye unesizungu. Ngoko ke , musa ukuqhuba okanye ukusebenzisa oomatshini ude wazi ukuba eli yeza likuchaphazela njani. Musa ukuphakama kwindawo ohleli kuyo okanye uhlale phantsi ngequbuliso, ingakumbi ukuba sele ukhulile.
- Ukulala ngequbuliso: Abanye abantu banokulala ngequbuliso ngaphandle kwesilumkiso ngelixa besebenzisa eli yeza. Oku kunokwenzeka ngelixa beqhuba, bethetha, okanye besitya. Ukuba oku kuyenzeka kuwe, xelela ugqirha wakho ngoko nangoko.
- Iminqweno engalawulekiyo: Abanye abantu baye baxela ukuba baneminqweno enamandla yokuzibandakanya kwimisebenzi efana nokungcakaza, ukwenza isondo, ukutya kakhulu, okanye ukuthenga ngelixa besebenzisa la mayeza. Ukuba ufumana nayiphi na kwezi ndlela zokuziphatha zingaqhelekanga, xelela ugqirha wakho ngoko nangoko.
- Isicaphucaphu nokuhlanza: Eli yeza linokubangela isicaphucaphu esinzima nokuhlanza. Ugqirha wakho angakunika elinye iyeza ukuthintela oku. Nangona kunjalo, ayizizo zonke iiyeza zesicaphucaphu ezinokusetyenziswa kunye neli yeza. Ngoko buza ugqirha wakho ukuba leliphi iyeza elifanelekileyo kuwe.
- Ukusetyenziswa kweNitroglycerin: Ukuba usebenzisa iNitroglycerin, uxinzelelo lwakho lwegazi lunokwehla ngequbuliso xa usebenzisa iApomorphine. Ke ngoko, ukuba usebenzisa ithebhulethi yeNitroglycerin engaphantsi kolwimi, kubaluleke kakhulu ukulala phantsi ngaphambi nasemva kokuyisebenzisa. Oku kunokunceda ukuthintela isiyezi kunye nokuwa.
Zithini iziphumo ebezingalindelekanga ezinokubakho zeyeza?
| Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko |
|---|
| Iimpendulo ze-allergy - ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala |
| Intlungu yesifuba (i-Angina) - intlungu, uxinzelelo, okanye ukuqina esifubeni, entanyeni, emqolo, okanye ezingalweni |
| Ukudideka, ukubona izinto ezingekhoyo |
| Ukulala ngequbuliso ngelixa usenza imisebenzi yemihla ngemihla |
| Utshintsho kwisingqisho sentliziyo - ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo, isiyezi, ukuquleka, iintlungu zesifuba, ubunzima bokuphefumla |
| I-Hemolytic anemia - ukudinwa okungaqhelekanga, ubuthathaka, isiyezi, intloko ebuhlungu, ukuphelelwa ngumphefumlo, umchamo omnyama, ukutyheli kolusu okanye amehlo |
| Uxinzelelo lwegazi oluphantsi - isiyezi, ukuquleka, umbono ofipheleyo |
| Iintshukumo ezintsha okanye ezandileyo ezingalawulekiyo zobuso, umlomo, okanye umzimba ongasentla |
| Izilonda zomlomo okanye zomqala, ukubomvu, ukudumba, kunye nentlungu |
| Ukudumba kwamaqatha, izandla, okanye iinyawo |
| Ukwenzeka kweminqweno engalawulekiyo ekhankanyiweyo apha ngasentla (njengokungcakaza, ukutya kakhulu) |
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza |
| Utshintsho kwincasa emlonyeni |
| Ukozela |
| Intloko ebuhlungu |
| Isicaphucaphu |
| Impumlo egobhozayo okanye impumlo exineneyo |
Uligcina kwaye ulilahla njani iyeza?
- Gcina kude nabantwana kunye nezilwanyana zasekhaya .
- Gcina kubushushu obuqhelekileyo begumbi (phakathi kwama-20-25 degrees Celsius).
- Gcina kwipakethi evaliweyo ide ilungele ukusetyenziswa.
- Buza ugqirha wakho ngendlela ekhuselekileyo yokulahla amayeza aphelelwe lixesha okanye angasafunekiyo.
Umyalezo Wokuya Ekhaya
- Ifilimu ye-Apomorphine sublingual liyeza elinikwa iziqephu zesifo sikaParkinson ngequbuliso, hayi iyeza lemihla ngemihla.
- Gcina izandla zakho zomile xa usebenzisa le nto, yibeke phantsi kolwimi lwakho kwaye uyivumele inyibilike. Ungaze uyihlafune okanye uyityumze.
- Eli yeza lingakwenza uzive ulele, ngoko ke lumka kakhulu xa usenza imisebenzi efuna ukugxila, ingakumbi xa uqhuba.
- Ukuba ufumana iminqweno engalawulekiyo okanye ezinye iziphumo ebezingalindelekanga, xelela ugqirha wakho ngoko nangoko.
- Kubaluleke kakhulu ukwazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
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