Ukuba unesifo seswekile sohlobo lwesibini, mhlawumbi sele usebenzisa amayeza afana neMetformin. Kodwa ugqirha wakho usenokuba ukuxelele ngodidi olutsha lwamayeza abizwa ngokuba yi-SGLT2 inhibitors. Okanye usenokuba uvile ngawo. Ngoko ke, zithini ii-SGLT2 inhibitors? Zisebenza njani ngokwenene? Kweli nqaku, siza kuthetha ngazo ngokulula nangokuchanekileyo.
Zithini ezi SGLT2 Inhibitors?
Ngamafutshane, ii-SGLT2 inhibitors luhlobo lweepilisi ezithathwa ngomlomo ezinceda ukulawula amanqanaba eswekile egazini lakho. Into ngazo kukuba zisebenza ngendlela eyahlukileyo kancinci kunezinye iziyobisi zeswekile.
Cinga nje, izintso zethu ziyindlela emangalisayo yokucoca. Xa sicoca igazi lethu, izintso zihluza iswekile ethile (iglucose) esegazini lethu iye kumchamo wethu. Nangona kunjalo, izintso zethu zineproteni ebizwa ngokuba yiSodium-glucose cotransporter 2 , okanye iSGLT2 ngamafutshane. Njengomgcini-sango, le protein yeSGLT2 ibamba uninzi lweswekile oluya kumchamo ize ilubuyisele egazini.
Ngaba uyaqonda ngoku? Umntu onesifo seswekile sele eneswekile ephezulu egazini. Ngoko ke into eyenziwa zezi zithinteli ze-SGLT2 kukucima loo mgcini-sango, iproteni ye-SGLT2, kancinci. Emva koko ayikwazi ukubuyisa iswekile ize iyongeze egazini. Ngenxa yoko, iswekile egqithisileyo ikhutshwa emzimbeni kumchamo . Le yindlela la mayeza anciphisa ngayo amanqanaba eswekile egazini lakho.
Olu hlobo lwamayeza luhlukile kuba luyehlisa iswekile egazini ngendlela eyahlukileyo, ngaphandle kokuchaphazela ngokuthe ngqo i-hormone insulin.
Zeziphi ii-SGLT2 Inhibitors eziqhelekileyo eSri Lanka nakwamanye amazwe?
Kukho iintlobo ezahlukeneyo zamayeza kweli qela. Onke enza into efanayo. Adla ngokuthathwa kube kanye ngemini, ngaphambi kwesidlo sokuqala sosuku. Ugqirha wakho uya kuvavanya imeko yakho aze akunike amayeza afanelekileyo.
| Igama eliqhelekileyo lesiyobisi | Igama lebrendi elisetyenziswa kakhulu |
|---|---|
| I-Canagliflozin | I-Invokana |
| I-Dapagliflozin | IFarxiga |
| I-Empagliflozin | IJardiance |
| I-Ertugliflozin | I-Steglatro |
| I-Bexagliflozin | IBrenzavvy |
Ngubani ofanelekileyo ukusebenzisa eli yeza?
Lo ngumbuzo obaluleke kakhulu. Izithinteli ze-SGLT2 aziloyeza lokuqala ugqirha angalinika isifo seswekile sohlobo lwesibini.
Ngokwesiqhelo, ugqirha uya kuqala acebise utshintsho kwindlela yokuphila , njengokulawula ukutya kunye nokuzilolonga, aze emva koko aqalise amayeza afana neMetformin.
Ugqirha wakho angacinga nge-SGLT2 inhibitor kwezi meko zilandelayo:
- Sele usela amayeza amaninzi, kodwa iswekile yakho egazini ayikalawuleki kakuhle .
- Ukuba unesizathu sezonyango sokuba kutheni ungenakusebenzisa amanye amayeza esifo seswekile.
- Ukuba usengozini yokuba neswekile ephantsi egazini (hypoglycemia) eyingozi.
- Ukuba ufuna ukunciphisa umzimba okanye ukunciphisa uxinzelelo lwakho lwegazi.
Ngubani ongafanele athathe eli yeza?
Olu hlobo lwamayeza alufanelekanga kuye wonke umntu.
- Eli yeza alivumelekanga kubantu abanesifo seswekile sohlobo loku-1 .
- Ezi azikhuthazwa kubantu abaye baba nengxaki enkulu yesifo seswekile ebizwa ngokuba yi -diabetic ketoacidosis .
- Eli yeza alizukuba luncedo kangako kumntu osele enesifo sezintso esinzima .
- Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa, ngokuqinisekileyo kufuneka uthethe nogqirha wakho malunga nokusebenzisa eli yeza. Akukho datha yaneleyo malunga nokhuseleko lwalo okwangoku. Ke ngoko, musa ukuqala okanye ukuyeka ukulisebenzisa eli yeza ngaphandle kokubonisana nogqirha.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, eli yeza linokubangela ezinye iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Kwaye uninzi lwazo lunokulawulwa.
| Imiphumela | Inkcazo kunye noko kufuneka ukwazi |
|---|---|
| Ukuchama rhoqo kunye nokunxanwa | Ngenxa yokuba iswekile ikhutshwa kumchamo, kunokufuneka uchame rhoqo emini nasebusuku. Oku kunokunyusa ukoma kwakho. Sela amanzi amaninzi. |
| Usulelo lomchamo kunye nolwesini | Iswekile emchameni inyusa umngcipheko we-yeast kunye nosulelo lweebhaktheriya. Xelela ugqirha wakho ukuba ufumana iimpawu ezinje ngokurhawuzelelwa, ukudumba, okanye intlungu kwindawo yesini. |
| Ukuhla ukusinda | Usenokunciphisa ubunzima ngenxa yokuba iswekile (iikhalori) iphuma emchameni. Oku kuyinzuzo kwabanye abantu. |
| Uxinzelelo lwegazi oluphantsi kunye nokuphelelwa ngamanzi emzimbeni | Ngamanye amaxesha, njengoko ulwelo luphuma emzimbeni, uxinzelelo lwegazi lunokwehla, nto leyo enokukwenza uzive udiniwe kwaye unesiyezi. |
| Isiphumo esibi kakhulu esifuna ingqalelo ngokukhawuleza | |
| I-Diabetic Ketoacidosis (DKA) | Le yimeko engaqhelekanga kodwa iyingozi kakhulu . Umzimba utshisa amafutha endaweni yeswekile, nto leyo evelisa ii-asidi ezibizwa ngokuba zii-ketones. Ukuba ufumana iimpawu ezifana nokucaphuka, ukuhlanza, iintlungu zesisu eziqatha, ukudinwa kakhulu, kunye nobunzima bokuphefumla, xelela ugqirha wakho ngoko nangoko okanye uye kwigumbi likaxakeka lesibhedlele elikufutshane (ETU). |
Ayisiyongxaki yesifo seswekile kuphela, kukho nezinye izibonelelo!
Nangona eli yeza laqalwa ukunyanga isifo seswekile, uphando lufumanise ukuba linezinye izibonelelo ezininzi ezimangalisayo.
1. Ukukhusela izintso: La mayeza anokunciphisa umonakalo kwizintso obangelwa sisifo seswekile kwaye alawule ukuqhubeka kwesifo sezintso esingapheliyo.
2. Ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo nokufa ngenxa yokuhlaselwa sisifo sentliziyo: Ezinye izithinteli ze-SGLT2 zibonakalisiwe ukuba ziyanciphisa umngcipheko wokulaliswa esibhedlele nokufa, ingakumbi xa zinikwa izigulana ezinesifo sentliziyo.
3. Ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo kunye nestroke: Ezinye izifundo zibonise ukuba ezi zinto zikwanegalelo ekunciphiseni umngcipheko wokuhlaselwa sisifo sentliziyo kunye nestroke.
Ngenxa yezi zizathu, oogqirha ngamanye amaxesha banokunika eli yeza kubantu abangenaso isifo seswekile kodwa abanesifo sezintso okanye sentliziyo.
Umyalezo Wokuya Ekhaya
- Izithinteli ze-SGLT2 ludidi olutsha lwamayeza athathwa ngomlomo anyanga isifo seswekile sohlobo lwesibini.
- Ezi zisebenza ngokuthintela izintso ekubuyiseleni iswekile egazini zize ziyikhuphe emchameni.
- La ayingomayeza okuqala anikwa isifo seswekile. Ugqirha wakho unokucebisa ukuba uwasebenzise xa iswekile yakho egazini ingalawulwa ngolunye unyango.
- Ukongeza ekulawuleni isifo seswekile, zikwanawo nokukwazi okumangalisayo ukukhusela izintso nokunciphisa umngcipheko wesifo sentliziyo.
- Njengakweminye imithi, kunokubakho iziphumo ebezingalindelekanga. Thetha nogqirha wakho malunga naluphi na utshintsho olufumanayo.
- Ngugqirha wakho kuphela onokugqiba ukuba eli yeza likulungele na, ngoko qiniseka ukuba uxoxa ngalo naye.
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