Isibindi sakho sinjani? Ake sixoxe ngokuhlolwa kokusebenza kwesibindi (ama-LFT)!

Isibindi siyisitho esibaluleke kakhulu emzimbeni wethu, akunjalo? Sifana nefektri encane emzimbeni wethu. Ngakho-ke kunezivivinyo zegazi ezikhethekile ezenziwayo ukuhlola ukuthi le fektri isebenza kahle noma cha. Yilokho esikubiza ngokuthi 'izivivinyo zomsebenzi wesibindi' noma Izivivinyo Zomsebenzi Wesibindi (LFTs) . Lokhu kunganikeza odokotela bethu ulwazi oluningi olubalulekile mayelana nempilo yesibindi sakho.

Kungani kwenziwa lezi zivivinyo zokusebenza kwesibindi (LFTs)?

Kulungile, manje cishe uyazibuza, 'Kungani wenza lokhu kwe-LFT?' Kungaba nezizathu eziningana.

Udokotela wakho angase afune ukuhlola ukuthi unesifo sesibindi, njenge -hepatitis, osisolayo. Noma, uma usuvele unesifo sesibindi, lokhu kuhlolwa kungasiza ekuboneni ukuthi siqhubeke kahle kangakanani, noma ukuthi ukwelashwa kuyasebenza yini. Enye into ukuthi eminye imithi ingathinta isibindi. Uma uthatha imithi enjalo, le mithi ye-LFT isetshenziselwa nokuqapha ukuthi iyasithinta yini isibindi sakho.

Yiziphi izinhlobo eziyinhloko zokuhlolwa kokusebenza kwesibindi?

Kalula nje, lokhu kuhlolwa kwe-LFT kulinganisa izinto eziningana kusukela kusampula yegazi lakho. Ngisho nangesampula yegazi elilodwa, kunganikeza ulwazi mayelana nama-enzyme namaprotheni ahlukahlukene akhiqizwa yisibindi. Ake sibone ukuthi yiziphi izinto eziyinhloko ezilinganiswayo?

Ukuhlolwa kwama-enzyme esibindi

Lokhu kuhlolwa kubheka izinhlobo eziningana zama-enzyme esibindini sakho. Isibonelo, ama-enzyme afana ne -alkaline phosphatase (ALP) , i-alanine transaminase (ALT) , i-aspartate aminotransferase (AST) , kanye ne-gamma-glutamyl transferase (GGT) yiwona ayinhloko. Uma kukhona umonakalo noma ukulimala kwesibindi, amazinga ala ma-enzyme egazini azokhula.

Ukuhlolwa kwe-protein ephelele

Lokhu kulinganisa izinga leprotheyini egazini lakho. Ubuwazi? Amaprotheni imizimba yethu ewadingayo akhiqizwa yisibindi. Ngakho-ke, uma izinga leprotheyini liphansi, kungasho ukuthi isibindi asisebenzi kahle.

Ukuhlolwa kwe-Bilirubin

I-Bilirubin ingumkhiqizo ongcolile. Isibindi siyithumela enyongweni. Ukwanda kwenani layo kusho ukuthi kungase kube khona okungahambi kahle ngesibindi.

Ukuhlolwa kwe-LDH

I-Lactate Dehydrogenase (LDH) nayo iyi-enzyme. Itholakala ezicutshini eziningi emzimbeni wethu, okuhlanganisa nesibindi. Izinga layo liphinde lisho okuthile ngempilo yesibindi.

Ukuhlolwa Kwesikhathi Se-Prothrombin (PT)

Lokhu kuhlolwa kulinganisa ukuthi kuthatha isikhathi esingakanani ukuthi isampula yegazi lakho lijiye. Isibindi siphinde senze amaprotheni adingekayo ukuze igazi lijiye. Ngakho-ke uma kuthatha isikhathi eside, lokho kungabonisa nobuthakathaka obuthile ekusebenzeni kwesibindi.

Njengazo zonke lezi zivivinyo, ngezinye izikhathi zifakwa njengengxenye yephakheji yokuhlolwa kwegazi ebizwa ngokuthi i-Comprehensive Metabolic Panel, evame ukwenziwa.

Yini esingayifunda kulezi zivivinyo?

Cabanga ngalo mbiko we-LFT njengendaba yabaphenyi. Udokotela wakho angakutshela okuningi ngokubheka amanani ahlukene kanye nezilinganiso kuwo. Isibonelo:

• Ingabe unesifo sesibindi, ukuvuvukala kwesibindi?
• Uma kukhona ukuvuvukala okunjalo, ingabe kubangelwa ukusetshenziswa kotshwala, noma kungenxa yesinye isizathu sokwakheka kwezicubu zomzimba?
• Ingabe inkinga isesibindini ngokwaso, noma emigudwini yenyongo?
• Ingabe ukusebenza kwesibindi kuyaphazamiseka? Uma kunjalo, ngezinga elingakanani?
• Ingabe kukhona okuvimbe ukugeleza kwenyongo? Uma kunjalo, ibukeka kanjani?
• Ingabe ikhona imithi oyiphuzayo ethinte isibindi sakho? Uma kunjalo, ngezinga elingakanani?

Lawa ma-LFT anikeza izinkomba ngezinto eziningi.

Lezi zivivinyo zesibindi (LFTs) zenziwa kanjani?

Kulula kakhulu. Isampula encane yegazi ithathwa emthanjeni osengalweni yakho. Bese ithunyelwa elabhorethri bese ihlolwa. Lapho, babheka ukuthi amazinga ezinto ezahlukahlukene aphezulu noma aphansi ngendlela engavamile. Ngokuvamile, baqhathanisa amazinga ama-enzyme noma amaprotheni ahlukahlukene. Ngoba uma lelo bhalansi lishintshwa, kulula ukuqonda ukuthi kukhona okungahambi kahle ngesibindi.

Kwenzekani ngesikhathi sokuhlolwa?

Ungenza lokhu kuhlolwa esibhedlela noma elabhorethri ekhethekile. Uchwepheshe uzoqala akhethe umthambo ofanele engalweni yakho bese ehlanza indawo. Bangase bafake nebhande lokucindezela engalweni engenhla ukusiza umthambo ubonakale kangcono. Ngemuva kwalokho, kufakwa inaliti encane emthanjeni bese kuqoqwa inani legazi elidingekayo ebhodleleni elincane. Lokhu kuthatha imizuzu embalwa kuphela, hhayi isikhathi eside. Ungakhathazeki, kuzozwakala sengathi intuthwane encane iyakuluma, yikho konke.

Ngemva kokuhlolwa?

Ngemva kokukhishwa kwegazi, isampula ithunyelwa elabhorethri ukuze ihlaziywe. Uma ilabhorethri itholakala esibhedlela noma esikhungweni esifanayo, imiphumela ingatholakala ngokushesha. Ingase itholakale emahoreni ambalwa noma ngisho nasezinsukwini ezimbalwa. Uma ungazizwa uphelelwa amandla ngemva kokunikela ngegazi, ungaya ekhaya, uphuze imithi yakho evamile, bese uphuza ukudla okulula noma isiphuzo.

Ngikuqonda kanjani okusembikweni wami we-LFT?

Uma uthola umbiko wakho we-LFT, uzobona amanani ezinto ezahlukahlukene. Ungawaqhathanisa nobubanzi obujwayelekile bese ubona ukuthi amanani akho aphezulu noma aphansi. Kodwa asho ukuthini ngempela lawa manani?Kudinga ulwazi oluncane ukuqonda lokho. Ngakho-ke, udokotela wakho uzokuchazela imiphumela futhi akufundise ukuthi uyifunda kanjani. Ungalokothi wenze izinqumo ezinkulu ngokusekelwe kule miphumela kuphela, kulungile? Kungcono ukukhuluma nodokotela.

"Into ebalulekile ukuthi, umbiko we-LFT umane nje uyingxenye yephazili. Udokotela angase adinge ulwazi olwengeziwe ukuze abone isithombe esigcwele."

Yiziphi izigaba ezijwayelekile zokuhlolwa kwesibindi? (Ziyini izigaba ezijwayelekile ze-LFTs?)

Lokhu kubalulekile futhi. Amabanga ajwayelekile angahluka kumuntu nomuntu. Lokhu kusho ukuthi la manani angahluka kancane kuye ngezici ezifana nobulili, usayizi womzimba, ngisho naselabhorethri nelabhorethri. Ngakho-ke, kufanele uqhathanise amanani akho 'nobubanzi obujwayelekile' obubhalwe embikweni wakho.

Noma kunjalo, nazi ezinye izindinganiso ezijwayelekile (lezi zenzelwe ulwazi olujwayelekile kuphela , sicela ubheke 'Uhla Olujwayelekile' oluthile embikweni wakho):

• I-Alanine Transaminase (ALT): 0 kuya ku-45 IU/L (Amayunithi Omhlaba Wonke Ngelitha)
• I-aspartate aminotransferase (AST): 0 kuya ku-35 IU/L
• I-alkaline phosphatase (ALP): 30 kuya ku-120 IU/L
• I-Gamma-glutamyl transferase (GGT): 0 kuya ku-30 ​​IU/L
• I-Bilirubin: 2 kuya ku-17 micromoles/L (ama-micromoles ngelitha)
• Isikhathi se-Prothrombin (PT): imizuzwana eyi-10.9 kuya kweyi-12.5
• I-Albumin: 40 kuya ku-60 g/L (amagremu ngelitha)
• Amaprotheni aphelele: 6.3 kuya ku-8.0 g/dL (amagremu nge-deciliter ngayinye)

Kusho ukuthini ukuthi i-AST ephezulu ne-ALT zisho ukuthini?

Uma amazinga ama-enzyme i-AST ne-ALT ephakanyisiwe, kungenzeka ukuthi kukhona umonakalo esibindini. Uma isibindi singaphansi kokucindezeleka, la ma-enzyme yiwo angase akhishwe egazini. Uma womabili ephakanyisiwe ngokulinganayo, kungenzeka ukuthi isibindi sonakaliswe yimbangela engeyona utshwala (isb., ukutheleleka, obunye ubuthi). Kodwa-ke, uma izinga le-AST liphakeme ngokuphindwe kabili kunezinga le-ALT, livame ukukhombisa umonakalo wesibindi obangelwa utshwala. Kodwa-ke, lokhu kumane kuyizinkomba, futhi udokotela kufanele abe nguye oqinisekisayo.

Yiziphi izinhlobo zezimo ezingasiza ekuxilongweni kwezivivinyo zokusebenza kwesibindi (LFTs)?

Lokhu kuhlolwa kwegazi kukodwa kungase kungakwazi ukusho ngokuqinisekile ukuthi hlobo luni lwesifo sesibindi onaso. Kodwa-ke, kungasiza udokotela wakho ukuthi akhiphe ezinye izimo. Ungadinga ukuhlolwa okwengeziwe ukuze uthole ukuxilongwa kokugcina. Isibonelo, ukuhlolwa kwezithombe, i-biopsy yesibindi, noma i-biopsy yengxenye encane yesibindi sakho.Noma izinto ezifana nokuhlolwa kwegazi ukuze kutholakale amagciwane athile.

Nazi ezinye zezimo ezingaboniswa yilawa ma-LFT:

• Isifo sesibindi esinamafutha
• I-hepatitis enobuthi
• I-hepatitis yokuzivikela komzimba
• I-hepatitis ebangelwa yigciwane (A, B noma C)
• I-Hemochromatosis - ukunqwabelana kwensimbi emzimbeni
• Isifo sikaWilson - ukuqongelela ngokweqile kwethusi emzimbeni
• Ukuntuleka kwe -Alpha-1 antitrypsin
• I-cholangitis eyinhloko ye-biliary (PBC)
• I-Cirrhosis - ukuqina kanye nokubopha izibazi zesibindi
• Umdlavuza wesibindi

Okokugcina, izinto okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

Ngakho-ke, ukuhlolwa kokusebenza kwesibindi, noma i-LFT, kuyindlela elula kakhulu yokuthi wena nodokotela wakho nifunde ngempilo yesibindi sakho. Kungakhathaliseki ukuthi ufuna isifo sesibindi noma ukubona ukuthi umuthi owuthathayo unomthelela yini, leli sampula elincane legazi lingakunikeza ulwazi oluningi.

Khumbula, i-LFT iyodwa ingase inganele ukwenza ukuxilongwa okuphelele. Kodwa-ke, ulwazi oluthola kulolu vivinyo lungaba usizo olukhulu ekunqumeni ukuthi yiziphi izinyathelo okufanele uzithathe ngokulandelayo. Ngakho-ke, uma udokotela wakho encoma i-LFT, kuwukuhlakanipha ukuyenza ngaphandle kokwesaba. Isibindi sakho sifana nomngane wakho omkhulu, futhi kungumthwalo wakho wemfanelo ukusinakekela kahle!

Isibindi , ukuhlolwa kwesibindi, ukuhlolwa kokusebenza kwesibindi, i-LFT, ukuhlolwa kwegazi, isifo sesibindi, i-Hepatitis