Wake waba nesisu esibuhlungu ngemva kokuthatha ama-antibiotic? Ake sifunde nge-C. diff (Clostridioides difficile)!

Ingabe usanda kuqala ukuba nesifo sohudo esibi ngemva kokuthatha umuthi wokulwa namagciwane? Noma ubulokhu uzwa ubuhlungu esiswini kanye nesifo sohudo izinsuku eziningi? Kungaba ngenxa yokutheleleka ngamagciwane esingakakuzwa okuningi ngakho, kodwa kungaba yingozi kakhulu. Namuhla, ake sixoxe ngokuthi iyini i-C. diff, ukuthi kungani yenzeka, nokuthi singazivikela kanjani.

Kuyini i-C. diff (Clostridioides difficile)?

Kalula nje, i-C. diff igama elifushane elinikezwa uhlobo lwebhaktheriya. Igama layo eliphelele yi-*Clostridioides difficile*. Leli bhaktheriya lingathelela amathumbu ethu amakhulu (ikholoni). Uma kwenzeka, libangela isifo sohudo kanye nezinye izimpawu eziningi ezingakhululekile.

Kujwayelekile ukuthola izifo ezibangelwa amagciwane emathunjini akho, futhi eziningi zazo azimbi kakhulu. Kodwa lokhu kutheleleka kwe-C. diff kumbi kakhulu, futhi kungalimaza ikholoni lakho. Lokhu kungenxa yokuthi amabhaktheriya e-C. diff akhiqiza ubuthi emathunjini akho. Lawa ma-toxin alimaza amangqamuzana amboze amathumbu akho, okubangela ukuba avuvuke. Ngokwezokwelapha, lokhu sikubiza ngokuthi i-colitis . Ukuthi uthola izimpawu nokuthi zimbi kangakanani kuncike ekutheni ubuthi buwenze umonakalo ongakanani emathunjini akho. Kwezinye izimo, lesi simo singasongela impilo.

Ziyini izimpawu zokutheleleka kwe-C. diff?

Uphawu oluyinhloko nolokuqala lwalesi sifo ukuhamba kwamathumbu ngamanzi (uhudo) . Uma lesi sifo singesibi kakhulu, ungase ube nokuhamba kwamathumbu cishe kathathu ngosuku, okuhambisana nokuqaqamba okuncane kwesisu.

Njengoba ukutheleleka kuya kuba kubi kakhulu, uhudo luya lubi kakhulu. Ungase ube nokunyakaza kwamathumbu okuyishumi noma okuyishumi nanhlanu ngosuku. Ungase futhi uqaphele igazi esithweni sakho. Lezi ezinye izimpawu ezingase zivele lapho isimo sibi kakhulu.

Ekuqaleni, lezi zimpawu zingase zibonakale njengokudla okunobuthi noma umkhuhlane wesisu. Uma uthatha ama-antibiotic, ungase ucabange ngephutha ukuthi lokhu kuphazamiseka kwesisu kuwumphumela ojwayelekile wemithi.

Iyini indle ekwelapheni i-C. diff?

Esifweni sohudo se-C. diff, indle ivame ukuba njengephalishi futhi ibe nkulu, ingabi namanzi ngokuphelele. Ngezinye izikhathi ingaba nombala oluhlaza okotshani. Ngezinye izikhathi, igazi, amafinyila, noma ubomvu kungabonakala.

Abantu abaningi babika ukuthi i-C. diff diarrhea inephunga elihlukile . Bayichaza njengephunga elinamandla nelimnandi kakhulu kunendle evamile. Lokhu kungenzeka ngoba amagciwane e-C. diff andisa amazinga e-bile acid esithweni sethu.

Kungani sithola i-C. diff?

Cabanga ngamathumbu ethu njengengadi enhle yezimbali. Kule ngadi, kunezimbali ezinhle kanye nokhula oluthile. Emathunjini omuntu onesimiso sokuzivikela somzimba esinempilo, kunamabhaktheriya amaningi "amahle" (njengezimbali) kanye namabhaktheriya "amabi" (njengokhula) alawulayo. I-C. diff yibhaktheriya evame ukuhlala emathunjini ethu ngamanani amancane.

Uma lokhu kulinganisela kuphazamiseka, okusho ukuthi kunamabhaktheriya amahle ambalwa, amabhaktheriya amabi njenge-C. diff anethuba lokusabalala njengokhula futhi athathe izintambo.

I-C. diff idluliselwa kanjani?

Ibhaktheriya i-C. diff ikhohlisa kakhulu. Uma iphuma emzimbeni, yakha igobolondo eliqinile kakhulu elibizwa ngokuthi i-spore. Lawa ma-spore afana nembewu encane yamabhaktheriya. Angaba sezandleni zethu nasezintweni esizithintayo (izibambo zeminyango, amatafula, izinto zokugezela). Uma sithinta indawo enala ma-spore, singagula, kungaba ukudla ukudla ngesandla esifanayo noma ukufaka izandla zethu emlonyeni wethu.

Lezi zinhlamvu kunzima kakhulu ukuzibulala. Zimelana nokushisa, ama-asidi, kanye nama-antibiotic amaningi kanye nemithi yokubulala amagciwane. Zingaphila futhi ezindaweni izinyanga eziningi. Yingakho lesi sifo sisakazeka ngokushesha kangaka, ikakhulukazi ezindaweni ezifana nezibhedlela.

Ubani osengozini enkulu yokuthola i-C. diff?

Abanye abantu banamathuba amaningi okuthola lesi sifo. Yilaba:

• Abantu abangaphezu kweminyaka engama-65 ubudala: Ingozi iphezulu ngoba amasosha omzimba ayancipha njengoba bekhula, bathatha imithi eminingi yezinye izifo, futhi bahlala ezibhedlela noma emakhaya asebekhulile.
• Izinsana ezincane: Ngoba amasosha omzimba wazo awakakhuli ngokugcwele.
• Abantu ezibhedlela: Izibhedlela ziyindawo lapho ama-spores e-C. diff angasakazeka kalula khona. Angadluliselwa kalula ngezindlu zangasese zomphakathi kanye nezindlu zangasese.
• Abantu abanezitho zomzimba ezibuthakathaka: Abantu abanezifo ezifana nomdlavuza, i-HIV, isifo sezinso, nesifo sikashukela banezitho zomzimba ezibuthakathaka. Abantu abathatha imithi yokucindezela amasosha omzimba nabo basengozini enkulu.
• Abantu abanezifo zamathumbu: Abantu abanezifo ezifana ne -Inflammatory Bowel Disease (IBD) , njengesifo sikaCrohn kanye ne-ulcerative colitis, basengozini enkulu yokutheleleka ngoba ungqimba oluvikelayo lwamathumbu lubuthakathaka.

Kodwa khumbula, ngisho nomuntu ongenazo lezi zinto eziyingozi angahlakulela i-C. diff.

Yiziphi izinkinga ezingaba khona ze-C. diff?

Esikhathini esiningi, ukutheleleka kwe-C. diff akukubi kangako. Kodwa ngezinye izikhathi, ikakhulukazi uma kungelashwa, kungaba nezinkinga ezinkulu.

• Ukutheleleka okuphindaphindiwe: Ngisho nangemva kokwelashwa, cishe abantu abangu-20% bazophinde babe nalesi sifo phakathi kwamasonto amabili kuya kwayisishiyagalombili.
• Ukuphelelwa amanzi emzimbeni: Uhudo oluningi lubangela ukuthi umzimba ulahlekelwe amanzi amaningi kanye nama-electrolyte. Uma lokhu kuba kubi kakhulu, kungabangela umfutho wegazi ophansi ngisho nokwehluleka kwezinso.
• I-Pseudomembrane colitis:Lesi yisimo esibi kakhulu (i-colitis). Ingaphakathi lamathumbu liyavuvukala futhi lijiye njenge-membrane.
• I-megacolon enobuthi: Lesi yisimo esingavamile kodwa esiyingozi kakhulu. Ikholoni livuvukala kangangokuthi liyeke ukusebenza ngokuphelele. Lokhu kungaholela ku -sepsis, isimo lapho amagciwane esakazeka khona emzimbeni wonke.

Ezimweni ezimbi kakhulu njengalezi, kungadingeka ngisho nokuhlinzwa ukuze kususwe ingxenye yamathumbu ethelelekile.

Dokotela, usithola kanjani lesi sifo? Iyini indlela yokwelapha?

Uma udokotela wakho esola ukuthi unegciwane le-C. diff ngokusekelwe ezimpawini zakho, uzokucela ukuthi unikeze isampula yendle. Izothunyelwa elabhorethri ukuze ihlolwe ukuthi ikhona yini ubuthi be-C. diff.

Uma lesi sifo siqinisekiswa, ukuhlolwa kwegazi kanye nokuskena okungenzeka kuhlolwe ngaphakathi kwamathumbu kungenziwa ukuze kutholakale ukuthi ukutheleleka kubucayi kangakanani.

Izindlela zokwelapha

Ukwelashwa kuncike ebunzimeni bokutheleleka.

• Ukuyeka ama-antibiotic: Uma uthola i-C. diff ngenkathi uthatha ama-antibiotic ngenxa yesinye isimo, into yokuqala udokotela wakho azokwenza ukuyeka umuthi. Kwabanye abantu, yilokho kuphela okudingeka bakwenze. Amabhaktheriya amahle esiswini sakho azokhula futhi ukutheleleka kuzophela ngokwako.
• Ama-antibiotic e-C. diff-specific: Uma lokho kungasebenzi, udokotela wakho angase akunikeze i-antibiotic ethile engabulala amabhaktheriya e-C. diff. Isibonelo , (i-Metronidazole) , (i-Vancomycin) , noma (i-Fidaxomicin) .
• Ukulaliswa esibhedlela: Uma ukutheleleka kukubi kakhulu, kungadingeka ukuthi ulaliswe esibhedlela, lapho unganikezwa khona usawoti (i-IV fluids) kanye nama-antibiotic afakwa emthanjeni.

Yini okufanele uyenze ngezifo eziphindaphindayo?

Abanye abantu baphinde babuyele esimweni sabo ngemuva kokwelashwa. Ezimweni ezinjalo, izinketho yilezi:

• Phinda ukwelashwa ngama-antibiotic: Kungase kunikezwe omunye umuthi wama-antibiotic noma wesikhathi eside.
• Ukufakelwa Kwe-Fecal Microbiota (FMT): Leli gama lingase lizwakale lingavamile, kodwa liyindlela yokwelapha ephumelela kakhulu ye-C. diff ephindaphindayo. Kalula nje, lihilela ukuhlukanisa amabhaktheriya 'amahle' kusampula yendle kumuntu ophilile bese ewafaka emathunjini esiguli. Lokhu kubuyisela ibhalansi yamabhaktheriya amahle alahlekile emathunjini.

Yini okufanele siyenze ukuze sivimbele ukusabalala kwe-C. diff?

Ngenxa yokuthi lesi sifo siyathelelana kakhulu, kudingeka siqaphele kakhulu. Ikakhulukazi uma othile emndenini enalesi sifo, qiniseka ukuthi uyazenza lezi zinto.

• Ukuzihlukanisa: Kungcono ukugcina umuntu onegciwane ekamelweni elihlukile uma kungenzeka. Kungcono nakakhulu uma engasebenzisa indlu yangasese ehlukile. Uma usebenzisa indlu yangasese yomphakathi, sula njalo indawo yangasese ngesihlanzi esine-bleach ngemva kokusebenzisa.
• Ukuhlanza indawo: Hlanza izindawo ezivame ukuthintwa (izibambo zeminyango, izibani) ngesisombululo esiqukethe i-bleach.
• Ukusebenzisa ama-antibiotic ngendlela efanele: Ungalokothi uthathe ama-antibiotic angakabhalwa ngudokotela. Thatha yonke imithi njengoba uyalelwe.

Kufanele ngimbone nini udokotela?

Uma unalezi zimpawu, bona udokotela wakho ngokushesha.

• Uma unesifo sohudo ngemva kokuqala imithi elwa namagciwane.
• Uma isifo sohudo sibi kakhulu (izikhathi ezingaphezu kweziyi-10 ngosuku).
• Uma ubona igazi esitulweni sakho.
• Uma unesifo sesisu esibuhlungu kakhulu kanye nomkhuhlane.
• Uma uhlanza uze ungakwazi ukudla noma ukuphuza.

Uma uhlangabezana nanoma yiziphi zalezi zimpawu, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela ngokushesha:

• Izimpawu zokuphelelwa ngamanzi emzimbeni (umlomo owomile, amehlo acwilayo, ukuphuma komchamo okuphansi kakhulu, ukukhathala okukhulu).
• Ubuhlungu besisu obukhulu, obungabekezeleleki.
• Ukudideka kwenkumbulo.

I-C. diff akuyona isifo okufanele sithathwe kalula. Kodwa ungesabi. Uma ubona udokotela ngesikhathi esifanele futhi uthola ukwelashwa, kungelapheka ngokuphelele.