Ingabe amaqhubu kanye nokuqubuka esikhumbeni sakho akuvamile? Ake sifunde nge-Cutaneous T-cell Lymphoma (CTCL)

Cishe uthola zonke izinhlobo zokuqubuka kanye namaqhubu esikhumbeni sakho, akunjalo? Ngezinye izikhathi kuyaxebuka futhi kuyaluma kakhulu. Sivame ukucabanga ukuthi lokhu kumane kuyisifo esivamile sokungezwani komzimba, i-eczema, noma i-psoriasis. Kodwa inkinga yesikhumba eqhubekayo engalulami iminyaka ngezinye izikhathi ingaba yinto engathi sína kakhulu. Leso ngesinye sezimo ezingavamile okufanele sonke siziqaphele.

Kuyini i-Cutaneous T-cell Lymphoma (CTCL)?

Kalula nje, i-CTCL uhlobo olungavamile kakhulu lomdlavuza wegazi oluthinta isikhumba sethu. Isikhumba siyisitho esikhulu kunazo zonke emzimbeni wethu. Lo mdlavuza uthinta isikhumba sethu ngqo. Empeleni ungoweqembu elikhulu lomdlavuza elibizwa ngokuthi `(non-Hodgkin lymphoma)`.

Manje ungase uzibuze ukuthi umdlavuza egazini ungafika kanjani esikhumbeni. Nokho, igazi lethu liqukethe uhlobo lweseli elimhlophe legazi elibizwa ngokuthi "ama-lymphocyte". Lawa yingxenye ebaluleke kakhulu yesistimu yomzimba wethu yokuzivikela. Olunye uhlobo lwala maseli e-lymph lubizwa ngokuthi "ama-T-cells". Ku-CTCL, la maseli e-T aba amaseli omdlavuza futhi aqala ukuhlukana ngokungalawuleki. Bese lawa maseli omdlavuza eza esikhumbeni futhi aqongelelane. Yilapho izimpawu zesikhumba ziqala khona ukuvela.

Ungesabi ukusho ukuthi umdlavuza. Abantu abaningi abane-CTCL bangakwazi ukulawula lesi sifo ngemva kokwelashwa (`remission`). Ngakho-ke bangaphila impilo evamile ngaphandle kokuphazamiseka okukhulu. Kodwa kuyinto evamile ukuzizwa ucindezelekile uma uthola ukuthi unomdlavuza. Udokotela wakho kanye nethimba lezokwelapha bahlala bekhona ukukusiza.

Yiziphi izinhlobo eziyinhloko ze-CTCL?

Kunezinhlobo eziningana ze-CTCL. Kodwa phakathi kwazo, kunezinhlobo ezimbili eziyinhloko ezibonakalayo. Ake siziqonde kahle lezi.

Yiziphi izimpawu zalesi sifo?

Izimpawu ze-CTCL zingahluka kumuntu nomuntu. Zifana kakhulu nezimo zesikhumba ezivamile, yingakho zivame ukuba nzima ukuzixilonga.

• Amaqhubu avela esikhumbeni. Ngezinye izikhathi lawa angaqhekeka abe yizilonda.
• Ukulahlekelwa izinwele .
• Isimo esifana nokuqubuka komzimba esibonakala kuwo wonke umzimba futhi sihlala siluma .
• Ukuvela kwamabala anombala oshintshile esikhumbeni.
• Ama-plaque alumayo, ngezinye izikhathi anamaxolo, asuke esikhumbeni.
• Ukuvuvukala kwezindlala ( emphinjeni , emakhwapheni, emiseleni, njll.).
• Ukuqina nokugoba kwesikhumba ezintendeni nasematheni .

Kungani lolu hlobo lwesifo luvela?

Sitshelwe ukuthi ku-CTCL, ama-T-cell aba amaseli anomdlavuza. Kodwa odokotela abasazi kahle ukuthi kungani lokhu kwenzeka. Kodwa kunezinto ezimbili okucatshangwa ukuthi zidlala indima.

1. Izinhlobo zezakhi zofuzo: Izakhi zofuzo zilawula ukusebenza kwamaseli ethu. Abacwaningi bathole ukuthi izinguquko (ukuguqulwa kwezakhi zofuzo) kwezinye izakhi zofuzo zingabangela lesi sifo.

2. Ukutheleleka: Cabanga ngalokho okwenzekayo lapho imizimba yethu ithola ukutheleleka okukhulu. Amasosha ethu omzimba alungiselela ukulwa. Lokho kusho ukuthi umongo wethu uqala ukukhiqiza amangqamuzana amhlophe egazi, ikakhulukazi ama-lymphocyte, ngesivinini esikhulu. Kufana nefektri ekhulisa umkhiqizo ngokuzumayo. Uma usebenza ngesivinini esikhulu kangaka, ngezinye izikhathi amaphutha angenzeka. Yileyo ndlela amaphutha angenzeka ngayo ku-DNA yamangqamuzana, okwandisa amathuba okukhula kwamangqamuzana omdlavuza.

Ubani osengozini enkulu yokuthola lesi sifo?

Lezi yizinto eziyingozi nje. Akuwona wonke umuntu onazo ozoqala ukuba nalesi sifo.

• Kulabo abaneminyaka engaphezu kwengu-50 ubudala.
• Amadoda asengozini enkulu kancane kunabesifazane.
• Kubantu abanezivikeli mzimba ezibuthakathaka (isibonelo, labo abaye bafakelwa izitho zomzimba).
• Ngokusho kwezinye izifundo, abantu bomdabu wase-Afrika.

Udokotela ukuthola kanjani lokhu?

Uma ubona udokotela ngenkinga yesikhumba, uzoqala ngokukubuza ngezimpawu zakho. Ngemuva kwalokho bazohlola isikhumba sakho kahle. Kodwa-ke, ukuze kuqinisekiswe ukuthi une-CTCL, kudingeka ukuhlolwa okuningana.

Yiziphi izindlela zokwelapha i-CTCL?

I-CTCL yelashwa ngokusekelwe ohlotsheni, esigabeni, kanye nempilo yakho iyonke. Akukho ukwelashwa okukodwa okulingana nakho konke. Udokotela wakho uzokwakha uhlelo lokwelashwa olukulungele kangcono.

• Okhilimu namafutha okugcoba asetshenziswa esikhumbeni: Lawa amakhilimu aqukethe imithi efana nama-steroids. Lawa anganele iziguli ezisesigabeni sokuqala.
• Ukwelashwa ngokukhanya (Phototherapy): Uhlobo olukhethekile lokukhanya kwe-ultraviolet (UV) luqondiswa esikhumbeni ukuze kubhujiswe amangqamuzana omdlavuza.
• I-Extracorporeal photopheresis (ECP): Lokhu kuyindlela yokwelapha eyinkimbinkimbi kancane. Lapha, ingxenye yegazi lakho iyathathwa, idluliselwe emshinini, lapho iphathwa khona ngomuthi nokukhanya ukwelapha amangqamuzana omdlavuza, bese ifakwa kabusha emzimbeni wakho.
• Ukwelashwa ngemisebe: Imisebe enamandla aphezulu isetshenziselwa ukubhubhisa amangqamuzana omdlavuza esikhumbeni.
• Ukwelashwa Ngezifo Ezingalawuleki: Sinikeza imithi evuselela amasosha omzimba ethu futhi iwenze alwe namaseli omdlavuza.
• Ukwelashwa ngamakhemikhali: Imithi enamandla ebulala amangqamuzana omdlavuza. Le mithi inganikezwa njengamaphilisi noma imijovo.

Impilo izoba njani ngalesi sifo?

Lona ngumbuzo omkhulu engqondweni yawo wonke umuntu. Izinhlobo eziningi ze-CTCL zikhula kancane kakhulu. Ngakho-ke, azisongeli impilo. Nakuba odokotela bengenakuyelapha ngokuphelele lesi sifo, ukwelashwa kungalawula ngempumelelo izimpawu.

Kodwa futhi sidinga ukuqonda iqiniso. Njenganoma yimuphi umdlavuza, i-CTCL ingaba yingozi uma ifinyelela ezigabeni eziphambili.

Ucwaningo lubonise ukuthi abantu abangu-9 kwabayi-10 abatholakale benalesi sifo ezigabeni zaso zokuqala (izigaba I noma II) basaphila ngemva kweminyaka eyi-10. Leso yisilinganiso sokusinda esingu-90%. Kulabo abanesifo esithuthukile, izinga lingu-53% kuphela. Lezi yizibalo nje. Umuntu ongcono kakhulu ukwazi kahle ukuthi isimo sakho siyini udokotela wakho.

Singanakekela kanjani isikhumba sethu futhi sinciphise ingozi?

Akukho esingakwenza ukuvimbela i-CTCL ukuthi ikhule, njengoba izici eziyingozi ezithinta yona zingenakushintshwa. Kodwa ukugcina amasosha ethu omzimba eqinile kuhle kuzo zonke izifo.

Futhi, uma une-CTCL, kubaluleke kakhulu ukunakekela isikhumba sakho.

• Gcina isikhumba sakho sinomswakama: Sebenzisa i-moisturizer enhle ngemva kokugeza kanye nosuku lonke. Lokhu kuzosiza ekunciphiseni ukoma, ukuxebuka, kanye nokulunywa.
• Zivikele ezifweni zesikhumba: Sebenzisa insipho engenaphunga kanye nensipho yokuwasha izingubo. Gqoka izingubo ezimboza isikhumba sakho uma uphuma elangeni, bese ufaka isivikelo selanga. Gqoka izingubo ezikhululekile neziphefumulayo.
• Yeka ukuklwebha: Ukuklwebha kuyinkinga enkulu kunazo zonke lezi ziguli ezibhekene nayo. Uma ziklwebha, ziphula isikhumba futhi amabhaktheriya angangena, okubangela izifo. Ngakho-ke, lawula ukuklwebha ngangokunokwenzeka. Ungathola impumuzo ngokwenza izinto ezifana nokugeza ngamanzi abandayo, ukugeza ngamanzi e-oatmeal, nokusebenzisa ama-antihistamine anconywe udokotela wakho.

Yiziphi izikhathi ezinhle kakhulu zokubona udokotela?

Uma usuqalile ukwelashwa, udokotela wakho kufanele akubone njalo. Kodwa uma kwenzeka into efana nale okwamanje, qiniseka ukuthi ukhuluma nodokotela wakho.

• Uma ubona noma yiziphi izinguquko ezintsha esikhumbeni sakho .
• Uma uzizwa sengathi unesifo sesikhumba (isib., sibomvu, sibuhlungu, sivuvukele, noma ubomvu buphuma).
• Uma unomkhuhlane ongaphezu kuka-100.4 Fahrenheit (38 Celsius) .

Ngokuvamile, uma sithola ubomvu noma i-mole esikhumbeni sethu, sicabanga ukuthi kuyinto evamile. Akekho ocabanga ukuthi kungaba umdlavuza ongavamile njengalona. Kodwa into ebaluleke kakhulu ukuthi, uma ubona ushintsho esikhumbeni sakho, ungalushayi indiva bese ulubonisa udokotela. Kungase kungabi umdlavuza. Kodwa uma kunjalo, ukuqala ukwelashwa ngokushesha ngangokunokwenzeka kuyinto engcono kakhulu ongayenza empilweni yakho.