Konke mayelana ne-hormone ye-FSH: Ikuthinta kanjani ukuzala kwakho? (I-hormone evuselela i-Follicle - FSH)

Cishe usulizwile igama elithi "ama-hormone" kakhulu, akunjalo? La ma-hormone alawula izinto eziningi emizimbeni yethu, njengemizwa, ukukhula, ukulala, kanye nendlala. Ngakho-ke, namuhla sizokhuluma nge-hormone ekhethekile ebaluleke kakhulu ekukhuleni ngokocansi kanye nekhono lokuba nezingane, okungukuthi, ukuzala. Leyo hormone yi-FSH, noma i-Follicle-Stimulating Hormone. Nakuba igama lingase libonakale liyinkimbinkimbi kancane, umsebenzi walo ulula kakhulu ukuwuqonda.

Kalula nje, iyini i-FSH?

I-FSH iyi -hormone ekhiqizwa yi-pituitary gland, i-gland encane ebuchosheni bethu. Umsebenzi wayo oyinhloko ukulawula ukusebenza kwama-ovari kwabesifazane kanye nama-testicles kwabesilisa.

Uma uzwa leli gama, abanye bangase bacabange ukuthi lokhu kuyinto ehlobene nama-follicle ezinwele. Kodwa akunjalo. Elinye iqembu lama-hormone abizwa ngokuthi ama-androgens lithinta ukukhula kwezinwele. I-FSH ithola igama layo ngoba ivuselela ama-sacs amancane agcwele uketshezi abizwa ngokuthi ama-ovarian follicles kuma-ovaries abesifazane. La ma-follicle aqukethe amaqanda.

Yimiphi imisebenzi ye-hormone ye-FSH?

I-hormone ye-FSH ibalulekile ngezindlela ezahlukene ezigabeni ezahlukene zokuphila kwethu. Ake sibone ukuthi kanjani.

Ukuthuthukiswa komntwana esibelethweni

Ngokumangalisayo, phakathi nezinyanga zesibili nezesithathu zokukhulelwa, kusukela emavikini angaba ngu-13 kuze kube yilapho kubeletha, i-pituitary gland yombungu iqala nokukhiqiza ama-hormone abizwa ngokuthi i-FSH kanye ne-LH (i-Luteinizing Hormone). Lawa mazinga ama-hormone afinyelela phezulu phakathi nokukhulelwa, njengoba i-ovarian follicle yokuqala noma i-seminiferous tubule yombungu ivuthwa.

Ngesikhathi sokuthomba

Ngesikhathi sobuntwana, amazinga e-FSH avame ukuba phansi kakhulu. Kodwa-ke, njengoba isikhathi sokuthomba sisondela, ngokuvamile phakathi kweminyaka eyi-10 neyi-14, i-hypothalamus ebuchosheni ikhiqiza i-hormone ebizwa ngokuthi i-GnRH (i-Gonadotropin-releasing hormone). Le GnRH itshela i-pituitary gland ukuthi iqale ukukhiqiza i-FSH ne-LH. Yilapho kuqala khona ukuvuthwa ngokocansi kanye nezinguquko zomzimba ezihlobene.

• Abafana: I-FSH ne-LH zisebenza ndawonye ukukhuthaza amasende ukuthi akhiqize i-testosterone . Le hormone inesibopho sezinguquko kubafana ngesikhathi sokuthomba, njengokukhula kwezinwele emzimbeni, ukujula kwezwi, kanye nokukhiqizwa kwesidoda.
• Kwamantombazane: I-FSH ne-LH zisebenza ndawonye ukukhuthaza ama-ovari ukuthi akhiqize i-hormone i-estrogen . Le hormone inesibopho sokuthuthukiswa kwamabele kanye nokuqala kokuya esikhathini .

Abesifazane abasesikhathini

Umsebenzi oyinhloko we-hormone ye-FSH ukulawula umjikelezo wokuya esikhathini kowesifazane osesikhathini. Kalula nje, i-FSH ivuselela ukukhula kwama-follicle kuma-ovari, ilungiselela amaqanda ukuvuthwa kwamaqanda. Njengoba la ma-follicle ekhula, akhipha i-estrogen kanye nenani elincane le-progesterone egazini.

Phakathi kwezinsuku 6 no-14 zomjikelezo wokuya esikhathini, i-FSH ibangela ukuthi ama-follicle amaningana esibelethweni aqale ukuvuthwa. Kodwa ezinsukwini 10-14, eyodwa kuphela yalezi follicle isuke isikhule yaba iqanda elivuthiwe ngokugcwele. Cishe ngosuku lwe-14, kuba nokwanda okungazelelwe kwe-hormone i-LH. Lokhu kubangela ukuthi i-follicle evuthiwe ngokuphelele iqhume futhi ikhulule iqanda. Yilokhu esikubiza ngokuthi i-ovulation .

Ngemva kokukhishwa kweqanda, i-follicle eqhumile iba yindlala yesikhashana ebizwa ngokuthi i-corpus luteum, ekhiqiza inani elikhulu le-hormone progesterone. Le progesterone iyamisa ukukhiqizwa kwe-FSH futhi ilungiselela udonga lwesibeletho ukukhulelwa.

Okwamadoda

Umsebenzi oyinhloko we-hormone yesilisa i-FSH ukukhuthaza ukukhiqizwa kwesidoda . I-FSH futhi isiza ukugcina ukukhiqizwa kwesidoda ngokusebenzisana ne-testosterone, ekhiqizwa yi-LH.

Ukukhiqizwa kwe-FSH kulawulwa kanjani?

Lolu uhlelo lokulawula oluyinkimbinkimbi kakhulu. Lufana nendlela inkampani enkulu esebenza ngayo. Silubiza ngokuthi i-hypothalamic-pituitary-gonadal axis. Izingxenye zobuchopho (i-hypothalamus, i-pituitary gland) kanye ne-gonads (ama-ovari/amasende) kulesi simiso zihlala zixhumana.

1. Ukuqala: Okokuqala, i-hypothalamus ikhiqiza i-hormone ebizwa ngokuthi i-GnRH.

2. Ukukhuthaza: Le GnRH iya e-pituitary gland bese iyitshela ukuthi ikhiqize amahomoni i-FSH ne-LH.

3. Isenzo: I-FSH ne-LH, ezikhiqizwa yi-pituitary gland, zihamba ngegazi bese zibopha kuma -ovari noma kuma-testicles (gonads) ukulawula ukusebenza kwazo.

4. Impendulo: Ngemuva kwalokho, ama-hormone akhiqizwa ama-ovari nama-testicles (njenge-estrogen ne-testosterone) athumela izimpawu ebuchosheni ukuze abutshele ukuthi ingakanani i-GnRH, i-FSH, ne-LH okufanele ikhiqize. Lokhu kuyaqhubeka ngomjikelezo.

Uma kukhona ukungasebenzi kahle okuncane noma kuphi kulesi simiso, ibhalansi yonke yama-hormone ingaphazamiseka.

Anjani amazinga ajwayelekile e-FSH?

Amazinga ajwayelekile e-FSH ayahlukahluka kuye ngobudala, ubulili, kanye nosuku lomjikelezo wokuya esikhathini kwabesifazane. Okubalulekile, ububanzi obujwayelekile bungahluka kancane phakathi kwama-lab. Ngakho-ke, kubalulekile ukuqhathanisa imiphumela yakho nobubanzi obujwayelekile beleb embikweni wakho. Uma unemibuzo mayelana nemiphumela yakho, qiniseka ukuthi ukhuluma nodokotela wakho.

Ngezansi kunamanani amukelwa ngokuvamile. Iyunithi yokulinganisa yi-mIU/mL (amayunithi angama-milli-international nge-milliliter).

Ingabe kukhona izinga le-FSH elifanele lokukhulelwa?

Lona umbuzo obaluleke kakhulu emibhangqwaneni enethemba lokuba nezingane. Ukulinganisa amazinga e-FSH kubalulekile lapho kuhlolwa ukuzala. Isikhathi esingcono kakhulu sokwenza lokhu kuhlolwa usuku lwesithathu lomjikelezo wokuya esikhathini (usuku lokuqala lokuya esikhathini lubhekwa njengosuku lokuqala).

Ucwaningo lwemiphumela yokwelashwa nge-IVF (In Vitro Fertilization) lubonise ukuthi labo abanamazinga e-FSH angaphansi kuka-15 mIU/mL ngosuku lwesithathu babenethuba eliphezulu lokukhulelwa kunalabo abanamazinga e-FSH aphakathi kuka-15 no-24.9. Labo abanamazinga e-FSH angaphezu kuka-25 babenethuba eliphansi kakhulu lokukhulelwa.

Kusho ukuthini ukuthi izinga le-FSH liphakeme?

Ezimweni eziningi, uma amazinga e-FSH ephakeme kunokuvamile, kusho ukuthi kunenkinga ngama-ovari noma amasende .

Cabanga ukuthi ama-ovari noma ama-testicles awakhiqizi i-estrogen noma i-testosterone eyanele. Bese kuthi i-pituitary gland ebuchosheni iqaphele lokhu bese icabanga ukuthi, "Kulungile, ngidinga ukuthumela i-FSH eyengeziwe ukuze lezi zinto zisebenze," bese ikhipha i-FSH eningi egazini. Kodwa ngenxa yenkinga ngama-gonad, awakwazi ukuphendula kahle enanini le-FSH elingenayo. Lesi simo sibiza ngokuthi i-primary hypogonadism . Okulandelayo kungabangela lokhu:

• Izinkinga zokuzalwa:
• I-Klinefelter syndrome emadodeni
• I-Turner syndrome kwabesifazane
• Izimbangela ezilandelayo:
• Ukwelashwa ngemisebe noma nge-chemotherapy yomdlavuza
• Ukulimala kwama-ovari noma amasende
• Ukwehla kwamazinga e-hormone ngokuguga
• Ezinye izimo zokuzivikela komzimba
• Izifo ezifana ne-mumps

Futhi, ukunqamuka kokuya esikhathiniAmazinga e-FSH kwabesifazane akhuphuka ngokwemvelo uma bekhipha amaqanda. Lokhu kuvamile. Uma amazinga e-FSH ezingane ephakeme kuneminyaka yabo kanye nezici zobulili ezithuthukayo, kungaba uphawu lokuthomba ngaphambi kwesikhathi .

Kusho ukuthini ukuthi izinga eliphansi le-FSH lisho ukuthini?

Uma amazinga e-FSH ephansi kunokuvamile, kuvame ukukhombisa inkinga nge-pituitary gland noma i-hypothalamus . Ngenxa yokuthi ubuchopho abubonisi ukukhiqizwa kwe-FSH, ama-ovari noma ama-testicles awasebenzi kahle. Lesi simo sibizwa ngokuthi i-hypogonadotropic-hypogonadism .

Lokhu kungase kube ngenxa yalokhu:

• Izinkinga ze-pituitary gland: Izinto ezifana ne-pituitary adenomas zingabangela ukuthi i-gland icindezelwe noma yonakale, okungaphazamisa ukukhiqizwa kwama-hormone.
• Izinkinga ze-Hypothalamic: Izimo zezakhi zofuzo ezingavamile njenge-Kallmann syndrome zingabangela ukwehla kokukhiqizwa kwe-hormone i-GnRH, okungaholela ekwehleni kwamazinga e-FSH.

Ziyini izimpawu zamazinga e-FSH angajwayelekile?

Kungakhathaliseki ukuthi amazinga e-FSH aphansi noma aphezulu, izimpawu zivame ukufana neze- hypogonadism , okungukuthi, ama-gonad angasebenzi kahle. Lezi zimpawu ziyahlukahluka ngobudala nobulili.

Amazinga e-FSH alinganiswa kanjani?

Izinga lakho le-FSH lingalinganiswa ngokuhlolwa kwegazi okulula . Kanye nalokhu kuhlolwa, udokotela wakho angase ancome ezinye izivivinyo eziningana zamahomoni ukuze athole isithombe esiphelele sesimo sakho.

• I-hormone ye-luteinizing (LH)
• I-Testosterone
• I-Estradiol kanye/noma i-progesterone

Lezi zivivinyo zivame ukwenziwa:

• Ukuthola imbangela yokungazali
• Ukuthola izinkinga ngama-ovari noma amasende
• Ukuthola izinkinga nge-pituitary gland noma i-hypothalamus
• Ukuthola izimbangela zokuya esikhathini okungajwayelekile
• Ukwazi ukuthi ukunqamuka kokuya esikhathini kuyasondela yini
• Ukuthola izimbangela zokubalwa kwesidoda okuphansi
• Ukuthola izizathu zokuthi kungani ukuthomba ezinganeni kubambezeleka noma kusenesikhathi.

Kufanele ngimbone nini udokotela?

Uma wena noma ingane yakho ninesinye noma ngaphezulu kwalezi zimo ezilandelayo, kubaluleke kakhulu ukubona udokotela ukuze uthole iseluleko.

• Uma unezimpawu ze-hypogonadism okukhulunywe ngazo ngenhla (njengokuncipha kwesifiso socansi, ukukhathala ngokweqile, ukungazali).
• Uma ingane yakho ingena ekuthombeni ngaphambi noma ngemva kwesikhathi esijwayelekile .
• Uma ukhulelwe kodwa unenkinga yokukhulelwa .

I-FSH iyi-hormone ebalulekile ekukhuleni kocansi kanye nokuzala emzimbeni wethu. Ngenxa yokuthi ixhumene kakhulu namanye ama-hormone amaningi, ngezinye izikhathi amazinga ayo angaba angajwayelekile. Kodwa ungakhathazeki ngakho. Uma ucabanga ukuthi wena noma ingane yakho ninenkinga ngalokhu, khuluma nodokotela. Bahlala bekulungele ukukusiza.