Uyafuna ukwazi nge-Glutamine? Ake sixoxe ngayo kalula!

Cishe uke wezwa igama elithi "glutamine" ndawana thize. Mhlawumbe kumngane, noma ku-inthanethi, noma ngisho nakudokotela. Ngakho-ke, iyini le glutamine? Ibaluleke kangakanani ngempela emizimbeni yethu? Namuhla, sizoxoxa ngakho konke lokhu ngendlela elula kakhulu, ngendlela ongayiqonda.

Uyazi ukuthi iyini le glutamine?

Kalula nje, i-Glutamine uhlobo lwe-amino acid etholakala emizimbeni yethu. Igama elithi amino acid lizwakala lingavamile kuwe, akunjalo? Cabanga ngale ndlela, njengoba nje ukwakha indlu kudinga izitini, imizimba yethu idinga lawa ma-amino acid ukuze yakhe amaprotheni. Ngakho-ke i-Glutamine ifana "nesitini" sokwakha amaprotheni.

Lawa maprotheni asiza imizimba yethu ukuthi yenze izinto eziningi. Isibonelo, amaprotheni abalulekile ezintweni eziningi, njengokwelapha amanxeba, ukugcina amathumbu ethu esebenza kahle, nokusiza amasosha omzimba ukuthi asivikele ezifweni. Ngakho-ke, njengengxenye yokwenza la maprotheni, i-glutamine nayo idlala indima enkulu kule misebenzi.

Ingabe i-Glutamine ibalulekile emizimbeni yethu?

Nansi into encane. I-Glutamine "iyi-amino acid engabalulekile ngokwemibandela." Lokhu kuzwakala kudida kancane, akunjalo? Ngizokugcina kulula.

"Okungabalulekile" kusho ukuthi sikuthola ekudleni, futhi kukhiqizwa nasemizimbeni yethu. (Kodwa-ke, ama-amino acid "abalulekile" awakhiqizwa emizimbeni yethu, kumelwe siwathole ekudleni.)

"Okunemibandela" kusho ukuthi nakuba imizimba yethu ivame ukukhiqiza i-glutamine eyanele ngaphakathi, kwezinye izimo ezikhethekile imizimba yethu idinga i-glutamine eyengeziwe .

Cabanga ngakho, uma unesifo somkhuhlane, noma ukulimala okuncane, umzimba wakho usebenzisa kakhulu le glutamine. Ngezikhathi ezinjalo, inani elikhiqizwa emzimbeni lingase linganele. Ngemuva kwalokho kufanele sithole i-glutamine eyengeziwe ngaphandle, kungaba ngokudla noma mhlawumbe ngezithasiselo.

Kodwa-ke, abantu abadala abaningi abanempilo bavame ukukhiqiza i-glutamine eyanele emizimbeni yabo, ngakho-ke lokhu akuyona into okufanele ikhathazeke ngayo ngaso sonke isikhathi.

Ingabe zikhona izinhlobo ze-Glutamine?

Yebo, kunezinhlobo ezimbili eziyinhloko. Ziyi-L-glutamine kanye ne-D-glutamine.

Kulezi ezimbili, ebaluleke kakhulu emisebenzini yomzimba wethu yi-L-glutamine . Esikhathini esiningi, uma umuntu ethi "glutamine," ubhekisela kule L-glutamine.

I-Glutamine iwusiza kanjani umzimba wethu?

I-Glutamine ayiyona nje into yokwakha amaprotheni. Yenza okungaphezu kwalokho.

• Lokhu kusiza futhi ekwenzeni amanye ama-amino acid .
• Kuphinde kusize ekususeni imfucuza engafuneki emizimbeni yethu, njenge-ammonia .
• Lokhu kubaluleke kakhulu nasezinqubweni zamakhemikhali ezinikeza imizimba yethu amandla ayidingayo, okungukuthi, izinqubo ze-metabolic.

I-Glutamine isiza kakhulu lezi zinhlelo zethu:

Siyakuhalalisela isimiso somzimba sokuzivikela!

Isimiso somzimba sokuzivikela sinjengebutho elilwela ukuvikela imizimba yethu ezifweni. Ngakho-ke, i-glutamine ingenye yamafutha ayinhloko ahlinzeka ngamandla adingekayo kulesi simiso somzimba sokuzivikela.

• Amaseli amhlophe egazi emizimbeni yethu asebenzisa le glutamine ukuze asivikele emagciwaneni futhi asigcine siphilile.
• Lokhu kubaluleke kakhulu nasezinqubweni ezilungisa izicubu ezilimele emzimbeni.

Kusiza uhlelo lokugaya ukudla!

Ubuwazi ukuthi iningi lamaseli amhlophe egazi ohlelweni lwethu lokuzivikela komzimba litholakala emathunjini ethu? I-Glutamine iqinisa udonga lwamathumbu, iluvimbele ukuthi lungalimali. Iphinde isize ekugcineni uhlelo lwamathumbu luphilile.

Yikuphi ukudla okuqukethe i-glutamine?

Iningi le-glutamine esiyithola ekudleni livela ekudleni kwezilwane okucebile ngamaprotheni, kodwa litholakala nakwezinye izinhlobo zokudla.

• Inyama: Njengenyama yenkomo, ingulube, inkukhu.
• Imikhiqizo yobisi: amaqanda, ubisi, iyogathi, ushizi.
• Okunye ukudla okusekelwe ezitshalweni okucebile ngamaprotheni: amantongomane ahlukahlukene, i-tofu.
• Imifino: ummbila, iklabishi elibomvu.
• Okusanhlamvu: ilayisi, i-oats.

Kubantu abaningi abanempilo enhle, bathola i-glutamine eyanele ekudleni kwabo okuvamile. Asikho isidingo sokukhathazeka ngakho. Ngoba, njengoba ngishilo ngaphambili, umzimba ungazenzela wona uma uwudinga.

Kukuziphi izimo lapho i-Glutamine isetshenziswa khona njengesengezo?

I-Glutamine, ekhiqizwa yimizimba yethu, ibaluleke kakhulu empilweni yethu iyonke kangangokuthi ososayensi basacwaninga ngezinzuzo zokuthatha izithasiselo ze-glutamine. Kodwa-ke, ucwaningo oluningi lubonisa ukuthi abantu abanempilo abadingi izithasiselo ze-glutamine. Umzimba onempilo ungenza i-glutamine eyanele futhi ungayithola ekudleni okuvamile.

Kodwa-ke, ucwaningo oluthile luthole ukuthi ukuthatha i-glutamine kungaba nezinzuzo ezithile ekwelapheni izimo ezithile zezokwelapha. Kodwa-ke, ubufakazi abucaci ngaso sonke isikhathi. Ezimweni eziningi, kudingeka ucwaningo olwengeziwe ukuze kuqondwe izinzuzo zangempela zokuthatha i-glutamine.

Manje ake sibone ukuthi le glutamine ikhulunywa ngaphansi kwaziphi izimo:

Isifo Se-Sickle Cell (SCD)

Ukuphela kwesikhathi lapho i-U.S. Food and Drug Administration (FDA) ivumile ukusetshenziswa kwe-glutamine ukunciphisa izinkinga ezinkulu zesifo se-sickle cell. Lesi sifo sibangela ukuthi amangqamuzana abomvu egazi ashintshe isimo. Lawa maseli abomvu egazi anomumo ongavamile angabhajwa emithanjeni yethu yegazi (imithambo yegazi, imithambo yegazi, ama-capillary). I-L-glutamine (igama lomkhiqizo: i-Endari®) inganciphisa izimpawu ezifana nobuhlungu.

Ukusha noma ukulimala

Ngesikhathi sokulimala, njengokusha okukhulu, ukuhlinzwa, noma okunye ukulimala okukhulu, amazinga e-glutamine emzimbeni wethu angancipha. Uma singenayo i-glutamine eyanele, amasosha ethu omzimba awakwazi ukusebenza kahle.

Ucwaningo oluthile lusikisela ukuthi ukunikeza i-glutamine eyengeziwe kubantu abagula kakhulu noma abalimele kungaba wusizo . Kungasiza ekuvimbeleni noma ekunciphiseni ukutheleleka ngemva kokuhlinzwa. Kungase futhi kunciphise umonakalo ezithweni zangaphakathi ngemva kokusha okukhulu. Ezifundweni eziye zabonisa izinzuzo ze-glutamine kulezi zimo, i-glutamine ivame ukunikezwa iziguli zasesibhedlela ngepayipi yokondla.

Kodwa-ke, akukacaci ngokuphelele ukuthi wonke umuntu uzothola imiphumela efanayo yini ngokuthatha i-glutamine ngemva kokulimala. Kungahluka kuye ngesiguli futhi kuye ngesimo.

Umdlavuza

Njengamaseli aphilile, amaseli omdlavuza asebenzisa i-glutamine njengomthombo wamandla okukhula kwawo nokusabalala kwawo. Eqinisweni, amaseli omdlavuza asebenzisa i-glutamine eningi kunamaseli aphilile. Ngezinye izikhathi asebenzisa i-glutamine eningi kangangokuthi amaseli aphilile awanakho ngisho nokwanele ukwenza umsebenzi wawo. Yingakho iziguli zomdlavuza zinamazinga aphansi e-glutamine.

Ososayensi bacwaninga ngezindlela zokuvimba la maseli omdlavuza ekusebenziseni i-glutamine, kodwa lolo cwaningo lusesesigabeni salo sokuqala.

Kodwa i-glutamine ayisona nje isakhi esilwa nomdlavuza. Iphinde ibe nezinzuzo ezigulini zomdlavuza. Ezinye izifundo zikhombisile ukuthi ukwengezwa kwe-glutamine kungasiza izicubu zelapheke ngemva kokwelashwa komdlavuza . Isibonelo, i-glutamine ingasiza ekunciphiseni ubuhlungu obubangelwa izilonda nokuvuvukala emlonyeni nasemphinjeni (mucositis) ngemva kokwelashwa ngamakhemikhali. Kungasiza futhi ekunciphiseni izimpawu ze-neuropathy ngemva kokwelashwa ngamakhemikhali.

Kudingeka ucwaningo olwengeziwe ukuze kuqondwe kahle ukuthi i-glutamine isiza kanjani ekunciphiseni imiphumela emibi yokwelashwa komdlavuza.

I-HIV/AIDS

Ezinye izifundo zisikisela ukuthi izithasiselo ze-glutamine zingaba usizo kubantu abane-HIV kanye ne-AIDS. I-Glutamine ingabasiza ukuthi baphinde bathole isisindo abasilahlekele ngemva kokuthola i-HIV. Kuthiwa futhi iyakwazi ukuthuthukisa ukusebenza kahle kwemithi yokulwa namagciwane esetshenziswa ukwelapha i-HIV.

Kodwa-ke, ucwaningo lusaqhubeka ngokuthi odokotela kufanele yini batuse lezi zithako ze-glutamine noma cha.

Isifo Sokuvuvukala Kwamathumbu (IBD)

Ngenxa yokuthi i-glutamine isiza ukugcina ulwelwesi oluvikelayo lwamathumbu, abanye abacwaningi baye bahlola ukuthi izithasiselo ze-glutamine zingabasiza yini abantu abanesifo samathumbu esivuvukalayo (i-IBD). I-IBD yisimo sokuvuvukala kwamathumbu esingamahlalakhona. Nakuba kwenziwe izifundo, ukwengezwa kwe-glutamine akukafakazelwa ukuthi kuyasiza i-IBD.

Ukusebenza kwezemidlalo kwabadlali

Abacwaningi baphinde bahlola ukuthi i-glutamine ingathuthukisa yini ukusebenza kwezemidlalo. Izifundo eziningana zikhombisile ukuthi i-glutamine ingasiza ekunciphiseni ubuhlungu bemisipha futhi inciphise ingozi yokulimala ngemva kokuzivocavoca okunamandla. Kodwa-ke, abukho ubufakazi obanele bokuthi lezi zinzuzo zihlala njalo. Umqondo wokuthi i-glutamine isiza abasubathi ukwakha imisipha awusekelwa ucwaningo.

Ngakho-ke, kufanele uthathe i-Glutamine?

Impendulo elula ithi: kuphela uma udokotela wakho ekuncoma. Uma unesifo se-sickle cell (SCD), udokotela wakho angakunikeza i-glutamine. Uma amasosha omzimba wakho edinga ukukhushulwa okwengeziwe, udokotela wakho angakweluleka ukuthi uthathe isithasiselo se-glutamine noma udle ukudla okuningi okucebile nge-glutamine.

Into ebaluleke kakhulu ukwazisa udokotela wakho nganoma yiziphi izithasiselo ozithathayo. Yilapho-ke kuphela lapho bezokwazi khona ukuthi ziphephile yini empilweni yakho.

Yiziphi izinzuzo zokuthatha lokhu?

Ukuthatha i-glutamine kunganciphisa ingozi yezinkinga zesifo se-sickle cell (SCD). Kungase futhi kube namandla athile okuvimbela ukutheleleka nokunciphisa ukulimala kwezicubu okungenzeka ngemva kokulimala (ukulimala noma ukusha) noma ukwelashwa komdlavuza, kodwa kudingeka ucwaningo olwengeziwe.

Ososayensi bayaqhubeka nokucwaninga ngezinye izinzuzo, kodwa lolo cwaningo lusesezigabeni zalo zokuqala.

Ingabe i-L-glutamine iyanciphisa amafutha esiswini?

Abukho ubufakazi obucacile nobuqinisekile bokuthi ukuthatha i-L-glutamine kunciphisa amafutha esiswini noma kusiza ekunciphiseni isisindo.

Ingabe ikhona imiphumela emibi?

Kudingeka ucwaningo olwengeziwe ukuze kuqondwe imiphumela emibi engaba khona yokusebenzisa i-glutamine isikhathi eside. Isibonelo, ukuthatha izithasiselo ze-glutamine kungashintsha indlela umzimba wakho osebenzisa ngayo ama-amino acid ukudala amandla. Yingakho kubalulekile ukukhuluma nodokotela wakho ngaphambi kokuthatha i-glutamine (noma esinye isithasiselo).

Nazi ezinye zemiphumela emibi emincane engase ivele lapho uthatha i-L-glutamine yesifo se-sickle cell (SCD):

• Ubuhlungu besisu
• Ukuhlungu obusemhlane
• Ukuqunjelwa
• Ikhanda elibuhlungu
• Isicanucanu

Uma uhlangabezana nanoma yikuphi ukusabela kokungezwani komzimba (isibonelo, ukuqubuka kwesikhumba noma amaqhubu), kufanele wazise udokotela wakho ngokushesha.

Okokugcina, izinto okufanele uzikhumbule

I-Glutamine iyi-amino acid eningi emizimbeni yethu futhi ebalulekile emisebenzini eyahlukahlukene. Kubaluleke kakhulu kangangokuthi kuvamile ukucabanga ukuthi ukuthatha isithasiselo se-glutamine kuzoletha izinzuzo ezinkulu zempilo. Kodwa-ke, ngaphambi kokuthatha isithasiselo se-glutamine, kubalulekile ukuba ngokoqobo ngobufakazi.

• Ukuthatha i-glutamine kusiza ngesifo se-sickle cell (SCD).
• Ezimweni "ezinemibandela" lapho imizimba yethu idinga i-glutamine eningi kunokujwayelekile, lokhu kungase kunikeze amasosha omzimba amandla engeziwe.
• Kodwa-ke, uma uphilile ngokwejwayelekile, abukho ubufakazi obanele bokuthi ukuthatha i-glutamine kunikeza izinzuzo ezinkulu zempilo.

Ngakho-ke, ngaphambi kokuthatha i-glutamine noma esinye isithasiselo, qiniseka ukuthi ukhuluma nodokotela wakho. Bangakweluleka ngezinzuzo nezingozi ezingaba khona ngokusekelwe esimweni sakho sempilo.

Uyaqonda? Uma uneminye imibuzo, ungabi namahloni okubuza udokotela.

I- Glutamine, ama-amino acid, amaprotheni, amasosha omzimba, ukugaya ukudla, izithasiselo, impilo