Ingabe uke waba ne-blood clot ngokuzumayo, noma waba nenkinga ethile ngesikhathi sokukhulelwa futhi udokotela wenza ukuhlolwa kwegazi? Ingabe ukhathazekile lapho umbiko uthi 'I-Lupus Anticoagulant positive'? Ingabe wesaba lapho ubona igama elithi 'lupus' wacabanga ukuthi lokhu kuyi-lupus? Leli gama empeleni liyadida kancane. Yingakho abantu abaningi benokungaqondi kahle ngalo. Ake silungise zonke izinkinga ngalokhu namuhla.
Iyini ngempela i-Lupus Anticoagulant?
Kalula nje, lolu uhlobo lwe-antibody olungaba khona egazini lethu.
Cabanga ngesimiso somzimba wethu sokuzivikela njengebutho elivikela izwe. Lapho igciwane noma into eyingozi ingena emzimbeni isuka ngaphandle, leli butho liyaqaphela leso sitha bese lidala iqembu lamasosha akhethekile, abizwa ngokuthi ama-antibodies, ukuze alibhubhise. Yilokhu okuvame ukwenzeka.
Kodwa, ngezinye izikhathi amasosha omzimba wethu ayaphambuka. Esikhundleni sokuhlasela abahlaseli bakwamanye amazwe, aqala ukuhlasela amangqamuzana ethu aphilile . Yileyo ndlela i-lupus anticoagulant (LA) eyi-antibody ekhiqizwa ngephutha futhi yonakalise imizimba yethu.
Le antibody ye-LA, kanye namanye ama-antibodies amabili, ingabangela isimo esibizwa ngokuthi i-Antiphospholipid Syndrome (APS) . Lesi yisifo esibangelwa ukuzivikela komzimba. Isici esiyinhloko salokhu ukuthi ingozi yokwakheka kwamahlule egazi emithanjeni yegazi yomzimba iphakeme kakhulu kunomuntu ojwayelekile.
Pho kungani lokhu kubizwa ngokuthi 'i-lupus'? Ingabe lesi yisifo esifanayo ne-lupus?
Yilapho abantu abaningi bedideka khona futhi besaba. Ngisho noma kukhona ingxenye 'ye-lupus' egameni, i-lupus empeleni iyizinto ezimbili ezihlukene: i-Lupus Anti-Coagulant (LA) nesifo se-Lupus. Yindaba ethakazelisayo kakhulu ukuthi leli gama lavela kanjani.
Le antibody yaqala ukutholwa emashumini eminyaka edlule lapho abacwaningi behlola amasampula egazi ezigulini ezine-lupus. Ngakho-ke bacabanga ukuthi yinto ethile ezigulini ezine-lupus.
Baphinde baphawula ukuthi amasampula egazi aqukethe le antibody athatha isikhathi eside kunokujwayelekile ukuze ajiye ngaphakathi kwe-vitro. I-'Anticoagulant' isho ukuthi 'ivimbela ukujiya kwegazi.' Ngakho-ke, bayiqamba ngokuthi 'i-lupus anticoagulant', okusho ukuthi 'into ethile emzimbeni weziguli ezine-lupus evimbela ukujiya kwegazi.'
Kodwa-ke, zombili lezo zicabango kamuva kwatholakala ukuthi azilungile. Eqinisweni, okuphambene nalokho kuyiqiniso. Lokho okwenziwa yile antibody ngaphakathi emzimbeni ukwandisa ukujiya kwegazi, hhayi ukukuvimbela!
Ukuze uqede lokhu kudideka, bheka ithebula elingezansi.
| Iqiniso | I-Lupus anticoagulant (LA) | Isifo se-Lupus (SLE) |
|---|---|---|
| Imvelo | I-antibody ethile eyingozi egazini. | Isifo esiyinkimbinkimbi sokuzivikela komzimba esithinta izitho ezahlukene zomzimba. |
| Umphumela oyinhloko | Kwandisa ingozi yokuqhekeka kwegazi. | Izinhlelo eziningi zingathinteka, njengesikhumba, amalunga, izinso, inhliziyo, kanye nobuchopho. |
| Ubudlelwano | Ukuba ne-LA akusho ukuthi une-lupus, kodwa abanye abantu abane-lupus bangase babe ne-LA. | I-LA iwukuthola okukodwa okungase kuhlotshaniswe ne-lupus. |
Kungani into efana nalena yenzeka emizimbeni yethu?
Lokhu kungenxa yokuthi amasosha omzimba wethu enza iphutha. Lawa ma-antibodies e-LA ahlasela amaprotheni anamathele kuhlobo oluthile lwento enamafutha ebizwa ngokuthi ama-phospholipid ebusweni bangaphandle bamaseli ethu. Lokhu kuhlasela kulimaza amaseli, kubangele ukuthi anamathele ndawonye futhi kwandise ingozi yokuqhekeka kwegazi.
Ochwepheshe abakaqiniseki ngokuphelele ukuthi kungani isimiso somzimba sokuzivikela siqala ukwenza la ma-antibodies anephutha kwasekuqaleni. Bakholelwa ukuthi kungenzeka ukuthi kungenxa yezakhi zofuzo, amathonya emvelo, noma ezinye izimo ezithathelwanayo.
Kusho ukuthini ukuthi i-LA positive? Kuzongithinta kanjani?
Ukuba ne-LA egazini lakho kusho ukuthi usengozini yokuthola isimo esibizwa ngokuthi i-antiphospholipid syndrome (APS). Lapha, 'usengozini'Igama elithi "intando" libaluleke kakhulu. Akusho ukuthi kuzokwenzeka nakanjani.
Ngisho noma i-antibody ye-LA ikhona egazini, kunabantu abaningi abahlala bephilile impilo yabo yonke ngaphandle kokukhula kwamahlule egazi noma izinkinga.
Ngakho-ke ungakhathazeki ngokungadingekile uma ubona lokhu embikweni wakho. Kodwa-ke, kubalulekile ukuthi udokotela wakho akuqaphele lokhu futhi akuqaphe. Njengoba kungenzeka kakhulu ukuthi ube namahlule egazi kunabanye, kuwukuhlakanipha ukukuqaphela.
Yiziphi izindlela zokwelapha lokhu?
Akukho ukwelashwa okwamanje okususa ngokuphelele le antibody ye-LA emzimbeni. Kodwa kunezindlela zokwelapha ezinhle kakhulu zokulawula umonakalo engase iwubangele, okungukuthi ukwakheka kwamahlule egazi.
Uma ungenazo izimpawu, okusho ukuthi awukaze ube ne-blood clot ngaphambili, udokotela wakho angase anqume ukukubheka ngaphandle kokukunikeza noma yimiphi imithi.
Kodwa-ke, uma uke waba ne-blood clot ngaphambili noma uke watholakala une-APS, ukwelashwa okuyinhloko ama-anticoagulant noma ama-blood thinners . Imithi efana ne-warfarin ne-heparin inikezwa ukunciphisa ingozi yama-blood clot. Ngezinye izikhathi, imithi efana ne -corticosteroids nayo inikezwa ukunciphisa ukusebenza ngokweqile kwesimiso somzimba sokuzivikela.
Zonke lezi zindlela zokwelapha zinqunywa udokotela wakho, ecabangela izici eziningi ezifana nesimo sakho, ubudala, nezinye izifo.
Kufanele ngimbone nini udokotela? Kuyini isimo esiphuthumayo?
Uma uphila nalesi simo, kubaluleke kakhulu ukwazi umehluko phakathi kwezimo ezivamile nezimo eziphuthumayo.
| Ithuba | Okufanele ngikwenze |
|---|---|
| Ukuqaphela okuvamile | Yiya emtholampilo ngesikhathi esibekiwe ukuze uyohlolwa njengoba kusho udokotela. Bazokwenza ukuhlolwa kwegazi ukuze babone ukuthi umthamo wemithi ulungile yini nokuthi kukhona yini ezinye izinguquko. |
| Isimo Esiphuthumayo (iya ku-ETU ngokushesha) |
|
Izimpawu eziyisixwayiso zokuqhekeka kwegazi
- Umlenze (Deep Vein Thrombosis - DVT): Ukuvuvukala okungazelelwe, ukubomvu, ukufudumala, kanye nobuhlungu emlenzeni owodwa.
- I-Pulmonary Embolism: Ukuphelelwa umoya ngokuzumayo, ubuhlungu obukhulu besifuba (ikakhulukazi uma uphefumula), ukukhwehlela igazi.
- Isifo sohlangothi: ukugoba kolunye uhlangothi lobuso, ukulahlekelwa yingalo eyodwa, ubunzima bokukhuluma.
Uma kuvela noma yiziphi zalezi zimpawu, hamba uye e-Emergency Treatment Unit (ETU) yesibhedlela ngokushesha .
Umlayezo Wokuya Nawe Ekhaya
- I-Lupus anticoagulant (LA) akuyona i-lupus ngokwayo. Iwuhlobo nje lwe-antibody egazini.
- Ukuba ne-LA egazini lakho kusho ukuthi usengozini enkulu yokuba nehlule legazi. Akusho ukuthi kuzokwenzeka nakanjani.
- Ungesabi ngemva kokubona umbiko. Kodwa qiniseka ukuthi ukhuluma nodokotela wakho ngalokhu bese ulandela iseluleko sakhe.
- Umgomo oyinhloko wokwelashwa ukuvimbela ukwakheka kwamahlule egazi. Udokotela wakho uzonquma inketho yokwelashwa engcono kakhulu kuwe.
- Hlala uqaphele izimpawu eziyisixwayiso zokuqhekeka kwegazi (ukuvuvukala emilenzeni, ubuhlungu besifuba, ubunzima bokuphefumula). Uma kuvela uphawu olunjalo, iya ku-ETU ngokushesha.
- Kuvamile ukuzizwa wesaba futhi ukhathazekile uma ucabanga ukuthi into ongayiboni emzimbeni wakho ingakulimaza. Esikhundleni sokuphila ngokwesaba, phila ngokuqwashisa nangokuqaphela. Udokotela wakho angakusiza kulolo hambo.
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