Ingabe nawe uzizwa ukhathele usuku lonke? Ingabe uzizwa ubuthakathaka futhi ungenampilo? Ingabe ngezinye izikhathi uzizwa sengathi iminwe nezinzwane zakho ziyaphazamiseka, noma uzizwa sengathi udliwa yizintuthwane? Abaningi bethu abazinaki lezi zinto, becabanga ukuthi zivamile. Kodwa lezi kungaba izimpawu ezincane zokuthi unesifo se-vitamin B12, okusho ukuthi umzimba wakho awutholi ngokwanele i-vitamin B12 oyidingayo. Ngakho-ke, namuhla sizokhuluma ngokuhlolwa okukhethekile okungakusiza ukuthola ukuthi unalesi simo ngempela. Leso yi-methylmalonic acid, noma ukuhlolwa kwe-MMA ngamafuphi.
Iyini i-methylmalonic acid (MMA) test?
Kalula nje, ukuhlolwa kwe-methylmalonic acid (MMA) ukuhlolwa kwegazi noma komchamo okuhlola ukuntuleka kwe-vitamin B12 emzimbeni wakho.
Cabanga ngalokhu. I-Vitamin B12 ibalulekile kumaseli emzimbeni wethu, ikakhulukazi ohlelweni lwezinzwa kanye nasekwakheni amaseli abomvu egazi. Njengoba nje imoto idinga uphethiloli ukuze isebenze, i-vitamin B12 ibalulekile kwezinye izinqubo ezibalulekile emzimbeni wethu.
Manje, lapho amazinga ethu e-vitamin B12 ephansi, noma lapho i-B12 esiyithathayo ingamuncwa kahle, ezinye zezinqubo zamakhemikhali emzimbeni wethu ziyayeka ukusebenza. Ngenxa yalokho, ikhemikhali ebizwa ngokuthi "i-methylmalonic acid" (MMA) iqala ukuqongelela emzimbeni.
Uma sikhuluma iqiniso, i-vitamin B12 ifana nesisebenzi esisusa "udoti" obizwa nge-MMA emzimbeni wethu. Uma isisebenzi se-B12 singekho, noma uma singakwazi ukwenza umsebenzi waso, lo mfucuza we-MMA uqoqana egazini nasemchameni. Ngakho udokotela wakho uzohlola isampula yegazi noma yomchamo wakho ukuze athole izinga le-MMA. Uma izinga liphezulu, kusho ukuthi ungase ungabi ne-vitamin B12 eyanele.
Kungani ngidinga ukwenza lolu vivinyo lwe-MMA?
Kunezizathu eziningana eziyinhloko zokuthi kungani udokotela wakho engase acele lokhu kuhlolwa. Ake sibheke ukuthi ziyini.
| Isizathu sokuhlolwa | Incazelo |
|---|---|
| Ukuba nezimpawu zokuntuleka kwe-vitamin B12 | Uma unalezi zimpawu, udokotela wakho angakuthumela kulolu vivinyo:
|
| Kwabasanda kuzalwa | Lokhu kuhlolwa kusetshenziselwa ukuthola ukuthi izinsana ezisanda kuzalwa zine -methylmalonic acidemia , okuyisimo esingavamile sofuzo. Lokhu kuvame ukwenziwa esibhedlela kungakapheli usuku noma ezimbili zokuzalwa. |
Ukuntuleka kwe-Vitamin B12 akuyona into elula. Uma kuqhubeka isikhathi eside, kungabangela ukulimala kwemizwa . Kungaholela nasezimweni ezifana ne-anemia eyingozi . Ngakho-ke, kubaluleke kakhulu ukukuthola nokukwelapha kusenesikhathi.
Kungani uhlola i-MMA ngaphandle kokubheka amazinga e-B12 ngqo?
Lona umbuzo abantu abaningi abanawo. Ungase uzibuze, "Uma ungahlola amazinga akho e-B12 ngqo egazini lakho, kungani ubheka okunye okubizwa ngokuthi i-MMA?"
Nasi isizathu. Ngezinye izikhathi, amazinga akho e-B12 egazini angase abonakale ejwayelekile embikweni wakho. Kodwa empeleni, amaseli omzimba wakho angase angakwazi ukusebenzisa leyo B12. Lokhu kubizwa ngokuthi i-bioavailability ephansi.
Kalula nje, ithangi lakho lamanzi ekhaya lingase ligcwele amanzi. Kodwa uma umpompi uphukile, awukwazi ukusebenzisa lawo manzi. Yilokho okwenzekayo nalapha. Ngisho noma une-B12 egazini lakho, akusizi ngalutho uma amangqamuzana akho engenakuyisebenzisa.
Ngakho-ke, ngisho noma i-B12 ingasetshenziswa, leyo mfucuza ebizwa nge-MMA esikhulume ngayo ngaphambili iqoqana emzimbeni. Ngakho-ke, ngokubheka izinga le-MMA, udokotela angathola isithombe esinembile . Lokhu kusho ukuthi ukuhlolwa kwe-MMA akukwazi nje ukuthola ukuthi umzimba wakho une-B12, kodwa futhi nokuthi isetshenziswa kahle yini . Lokhu kuwusizo olukhulu ekuboneni ukuntuleka kwe-B12 esiteji sokuqala.
Kwenziwa kanjani lokhu kuhlolwa futhi yini okufanele ngiyilungiselele?
Ukuze wenze ukuhlolwa kwe-MMA, uzocelwa ukuthi unikeze isampula yegazi noma isampula yomchamo. Udokotela wakho uzonquma ukuthi ungakwenza kanjani lokhu.
Ukulungiselela ngaphambi kokuhlolwa
Lokhu kungahluka kuye ngendlela yokuhlola oyibekelwe wena.
- Uma uhlolwa igazi, ungase ucelwe ukuba uzile ukudla amahora ambalwa , okusho ukuthi ngeke udle noma uphuze lutho.
- Uma uhlolwa umchamo amahora angama-24, ungase welulekwe ukuthi uyeke ukudla noma imithi ethile ngalolo suku.
Into ebaluleke kakhulu ukubuza udokotela wakho noma ilabhorethri ngalokhu bese ulandela imiyalelo yakhe.
Indlela yokwenza isivivinyo
| Indlela yokuhlola | Indlela yokukwenza |
|---|---|
| Ukuhlolwa Kwegazi | Lokhu kufana nokunikeza igazi elivamile. Elabhorethri, kusetshenziswa isirinji esincane ukukhipha igazi elincane emthanjeni ongalweni yakho, eduze kwendololwane yakho. Bese kufakwa iplasta encane endaweni. |
| Isampula yomchamo yamahora angama-24 | Ilabhorethri izokunikeza ibhodlela elikhethekile. Uzoyalwa ukuthi uqoqe wonke umchamo wakho ebhodleleni amahora angama-24. Ngemuva kwalokho udinga ukuyisa ibhodlela elabhorethri. |
| Isampula yomchamo evamile (Ukuhlolwa komchamo) | Lokhu kuhilela ukudlulisa inani elincane lomchamo enkomishini encane, ehlanzekile oyinikiwe. Lokhu kungenziwa ekhaya noma ehhovisi likadokotela wakho. |
| Kwabasanda kuzalwa | Esibhedlela, umhlengikazi oqeqeshiwe uhlaba isithende somntwana ngenaliti encane bese eqoqa amaconsi ambalwa egazi ekhadini elikhethekile. Lokhu akubuhlungu kakhulu enganeni. |
Ungaqhubeka nemisebenzi yakho evamile ngemva kokuhlolwa. Kungathatha noma yikuphi kusukela osukwini olulodwa kuya esontweni elilodwa noma amabili ukuthola imiphumela.
Ungayiqonda kanjani imiphumela?
Uma uthola umbiko wakho webhu, uzofaka inani le-MMA.
- Amanani ajwayelekile:Lawa manani angahluka kancane kusukela elabhorethri kuya kwelebhu. Ngokuvamile, amazinga e-MMA egazini kufanele abe ngaphansi kuka -0.40 µmol/L . Kodwa-ke, kungcono ukuhlola isigaba esithi "Ibanga Lokubhekisela" embikweni wakho.
Kwenzekani uma izinga le-MMA likhuphuka?
- Uma izinga lakho le-MMA liphezulu: Lokhu kubonisa ukuthi ungase ube nokuntuleka kwe-vitamin B12. Udokotela wakho cishe uzokwenza ezinye izivivinyo, njenge -homocysteine , bese ehlanganisa yonke le miphumela ukuze afinyelele esiphethweni. Uzobe esekunikeza ukwelashwa okudingekayo, isibonelo, amaphilisi noma imijovo ye-vitamin B12.
- Uma umntwana osanda kuzalwa enamazinga aphezulu e-MMA: Kungaba uphawu lwesifo sofuzo esibizwa ngokuthi i-methylmalonic acidemia . Udokotela uzoyala ukuhlolwa okwengeziwe ukuqinisekisa ukuxilongwa. Uma lesi simo sikhona, ukwelashwa kuhlanganisa ukudla okukhethekile kanye nezithasiselo zamavithamini.
Ingabe amazinga e-MMA angaphakanyiswa ngisho noma amazinga e-B12 ejwayelekile?
Yebo, ungakwazi. Lena yingxenye ebaluleke kakhulu yalolu vivinyo. Uma amazinga akho e-B12 egazini ejwayelekile kodwa amazinga akho e-MMA ephakanyisiwe, kusho ukuthi unesifo se-B12 esisencane noma esiphansi . Lokhu kusho ukuthi umzimba wakho une-B12 kodwa awusebenzisi kahle. Udokotela wakho uzonquma ukuthi udinga ukwelashwa noma cha.
Kufanele ngimbone nini udokotela?
- Uma unezimpawu zokuntuleka kwe-vitamin B12 esixoxe ngazo ngaphambilini (ukukhathala, ukuba ndikindiki, njll.), qiniseka ukuthi ubona udokotela wakho.
- Uma unemibuzo noma ubunzima bokuqonda imiphumela yakho yokuhlolwa, khuluma nodokotela wakho ngayo.
Ngezinye izikhathi, ulwazi mayelana nenkinga engxenyeni ethile yomzimba wethu lungatholakala kwenye ingxenye. Ukuhlolwa kwe-MMA kungenye yezivivinyo ezinjalo. Ngokulinganisa izinga le-MMA egazini noma emchameni, singathola ukuthi i-vitamin B12 isebenza kahle yini ngaphakathi kwamaseli omzimba wethu. Leli yithuba elibalulekile lokuhlonza nokuqala ukwelashwa kwezifo ngaphambi kokuba kwenzeke umonakalo wezinzwa. Ngakho-ke, ungagodli lutho futhi ukhulume nodokotela wakho ngalokhu.
Umlayezo Wokuya Nawe Ekhaya
- Ukuhlolwa kwe-Methylmalonic Acid (MMA) kuyindlela ebaluleke kakhulu futhi ebucayi yokuxilonga ukuntuleka kwe-vitamin B12.
- Ngisho noma amazinga e-B12 egazini lakho ejwayelekile, uma umzimba ungasebenzisi leyo B12, ingatholakala ngokuhlolwa kwe-MMA.
- Ungazinaki izimpawu ezifana nokukhathala okuqhubekayo, ubuthakathaka, kanye nokuba ndikindiki ezithweni zakho njengokujwayelekile. Kungaba izimpawu ezibalulekile zokuthi kufanele ubonane nodokotela.
- Uma unenkinga ngemiphumela noma izimpawu zokuhlolwa kwakho, qiniseka ukuthi ukhuluma nodokotela wakho. Ungalokothi uthembele emibikweni yelabhorethri ukuze uhlole isimo.
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