Uma ucabanga ngesifo sikashukela, cishe ucabanga kuphela ngoHlobo 1 noHlobo 2. Iningi labantu emphakathini wethu liyazazi futhi likhuluma ngalezi zinhlobo ezimbili eziyinhloko. Kodwa bewazi ukuthi kunezinhlobo zesifo sikashukela ezingezona ezalezi zigaba ezimbili, ezihlukile kancane, futhi esingakazwa kakhulu ngazo? I-MODY ne-LADA ziyizinhlobo ezimbili zesifo sikashukela ezingavamile, kodwa ezibaluleke kakhulu okufanele ziqashelwe. Lezi zingaba nezinye zezici zoHlobo 1 noHlobo 2, kodwa zinezimpawu zazo ezihlukile kanye nokwelashwa. Ake sixoxe ngalokhu kalula nangendlela enobungane namuhla.
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Ake siqale sibone ukuthi iyini i-MODY? (Isifo Sikashukela Sokukhula Kwabantu Abasebasha)
Kalula nje, i-MODY yisimo sofuzo esibangela isifo sikashukela. Cabanga ngemizimba yethu njengefektri eyinkimbinkimbi. Le fektri ineziqondiso ezahlukene (izakhi zofuzo) zemisebenzi ehlukene. Ngakho-ke, uma kukhona ushintsho noma iphutha elincane (lokhu sikubiza ngokuthi ukuguqulwa kwezakhi zofuzo) kusethi yemiyalelo eyenza i-hormone ethi "Insulin", esiza umzimba ukuthi usebenzise ushukela ukukhiqiza amandla owadingayo, umzimba awukwazi ukwenza i-insulini ngendlela efanele. Bese izinga likashukela egazini liyakhuphuka. I-MODY yisimo esinjalo.
Njengoba igama lisho (Isifo Sikashukela Sokukhula Nokuqala Kwabantu Abasha), lesi simo sivame ukuvela kubantu abasha, kusukela ebusheni babo kuya ebudaleni babo. Kodwa-ke, asivamile kakhulu. Cishe abantu abangu-5% abanesifo sikashukela bane-MODY.
Ziyini izimpawu ze-MODY?
Izimpawu ze-MODY zingahluka kumuntu nomuntu ngoba uhlobo lwezimpawu luyahlukahluka kuye ngokuguqulwa kwezakhi zofuzo okukuthintayo.
Kodwa ngokuvamile, izimpawu ze-MODY zincane kakhulu futhi zikhula kancane. Yingakho abantu abaningi bethola ukuthi banalesi simo lapho ukuhlolwa kwegazi ngesinye isizathu kubonisa amazinga aphezulu kashukela egazini.
Kodwa uma kuvela izimpawu, zingase zifane nezinye izinhlobo zesifo sikashukela.
| Izimpawu ezivamile |
|---|
| Ukuzizwa womile kakhulu kunokujwayelekile. |
| Ukudinga njalo ukuchama. |
| Umbono ofiphele. |
| Ukutheleleka okuvamile (ikakhulukazi isikhumba kanye nomgudu womchamo). |
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Uma izinga likashukela egazini lakho seliqinisekisiwe ukuthi liphezulu, kunezizathu eziningana zokuthi kungani udokotela wakho engase asole ukuthi ungase ube ne-MODY.
- Watholakala unesifo sikashukela usemncane .
- Isifo sikashukela sitholakala ezizukulwaneni eziningana zomndeni wakho (isibonelo, umama/ubaba wakho, kanye nogogo/umkhulu wakho, nabo babenesifo sikashukela).
- Awunazo izimpawu ezivamile zesifo sikashukela sohlobo 1 noma sohlobo 2 (isib. ukukhuluphala ngokweqile, umfutho wegazi ophakeme).
Uma udokotela wakho esola ukuthi une-MODY ngenxa yalezi zizathu, angase asikisele ukuthi uhlolwe izakhi zofuzo ukuqinisekisa isimo sakho se-MODY. Lokhu kuvame ukwenziwa ngokuthumela isampula yegazi noma yamathe elabhorethri.
Ngakho-ke iyini i-LADA? (Isifo Sikashukela Esizimele Esizimele Kwabantu Abadala)
Kulungile, manje usuyiqonda kahle i-MODY. Manje ake sibheke lolu hlobo olubizwa ngokuthi i-LADA. Abanye abantu ngokuhlekisa bayibiza ngokuthi "isifo sikashukela sohlobo 1.5." Kunesizathu salokho.
Njengesifo sikashukela sohlobo 1, i-LADA ibangelwa inkinga yokuzivikela komzimba . Kalula nje, uhlelo lokuzivikela lomzimba wethu (amasosha omzimba) luhlasela ngephutha futhi lubhubhise amaseli akhiqiza i-insulin kuma-pancreas ethu. Kufana nebutho elivikela izwe elihlasela ngephutha idolobha lalo.
Uma amaseli akhiqiza i-insulin ebhujiswa ngale ndlela, umzimba awukwazi ukulawula amazinga kashukela egazini. Kodwa-ke, umehluko omkhulu lapha uma uqhathaniswa nesifo sikashukela sohlobo 1 ukuthi lokhu konakala kwenzeka kancane kakhulu. Ngakho-ke kungathatha izinyanga, noma ngisho neminyaka, ngaphambi kokuba kuvele izimpawu futhi kudingeke ukwelashwa.
Ziyini izimpawu ze-LADA?
Izimpawu ze-LADA zifana kakhulu nezohlobo 1 nohlobo 2. Kodwa-ke, zivela kancane kancane.
| Izimpawu ezivamile |
|---|
| Ukuzizwa womile kakhulu futhi udinga ukuchama njalo. |
| Ukwehlisa isisindo naphezu kwesifiso sokudla esihle. |
| Umbono ofiphele. |
| Ukukhathala okukhulu kanye nobuthakathaka emzimbeni. |
| Isikhumba esomile nesilumayo. |
| Ukuzwa umuzwa wokucasuka ezithweni. |
| Ukutheleleka okuvamile. |
I-LADA ihlolwa futhi yelashwa kanjani?
I-LADA ivame ukuqala ngemva kweminyaka engama-30. Yingakho ngisho nodokotela ngezinye izikhathi bengacabanga ukuthi inesifo sikashukela sohlobo 2. Kodwa-ke, uma isimo sakho singalawulwa ngemithi evamile yohlobo 2, udokotela wakho angase asole i-LADA.
Ukuphela kwendlela yokuqinisekisa ukuthi une-LADA yini ukuhlolwa kwegazi. Lokhu kuhlola ama-antibodies egazini lakho akhiqizwe ngokumelene namaseli akhiqiza i-insulin kuma-pancreas akho. Ngaphezu kwalokho, udokotela wakho angase futhi ayalele ukuhlolwa ukuhlola amazinga akho ephrotheni ebizwa ngokuthi i-C-peptide, okuyisilinganiso sokuthi umzimba wakho ukhiqiza i-insulin engakanani.
Uma kukhulunywa ngokwelashwa, isifo sikashukela singalawulwa ezigabeni zokuqala ngemithi, ukudla kanye nokushintsha indlela yokuphila.
Kodwa khumbula, ku-LADA, umzimba ubhubhisa kancane kancane amangqamuzana enza i-insulin, ngakho-ke ngesinye isikhathi kuzodingeka uthathe imijovo ye-insulin ukulawula ushukela egazini lakho.
Umlayezo Wokuya Nawe Ekhaya
- Uma sikhuluma ngesifo sikashukela, akusiyona njalo i-Type 1 kanye ne-Type 2 kuphela. Kukhona nezinhlobo esingazazi kakhulu ngazo, njenge-MODY kanye ne-LADA, kodwa zibalulekile.
- I-MODYLuhlobo lwesifo sikashukela oluvela esemncane futhi lubangelwa imbangela yofuzo. Ukwelashwa kwaso kuncike ku-gene ethinta sona.
- I-LADA uhlobo lwesifo sikashukela olukhula kancane kancane lapho umuntu ekhula, olufana nesifo sikashukela soHlobo 1. Ngokuhamba kwesikhathi, luzodinga ukwelashwa nge-insulin.
- Uma unesifo sikashukela, noma othile emndenini wakho enaso, futhi izimpawu zakho noma impendulo yakho ekwelashweni ibonakala "ihlukile kancane," ungesabi ukukhuluma nodokotela wakho ngalezi zimo, ezibizwa ngokuthi i-MODY ne-LADA. Ukuthola ukuxilongwa okufanele kuyisinyathelo sokuqala sokuthola ukwelashwa okufanele.
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