Ingabe kukhona ushintsho kuma-hormone omzimba wakho? Masiqaphele i-Prolactinoma (i-Prolactinoma)

Ingabe umjikelezo wakho wokuya esikhathini usuvele ungajwayelekile? Noma ingabe kukhona ukuphuma koketshezi olumhlophe olufana nobisi emabeleni akho, noma ngabe awukhulelwe noma awuncelisi? Uma uyindoda, ingabe uke wabhekana nokwehla kwesithakazelo socansi noma ezinye izimo eziyinkinga? Isizathu salezi zinto kungaba yinto ongakaze uyicabange. Namuhla sikhuluma ngesimo esinjalo, okungukuthi, isifo esibizwa ngokuthi i-Prolactinoma.

Kalula nje, iyini i-Prolactinoma?

I-Prolactinoma iyisimila esikhula endlaleni encane eseduze kakhulu nobuchopho bethu, phansi kobuchopho, ebizwa ngokuthi i-pituitary gland. Manje, ungesabi uma sithi "isimila." Lesi isimila esingesona umdlavuza (esingesihle). Lokho kusho ukuthi akusona isimila esisongela ukuphila esisakazeka emzimbeni wonke njengomdlavuza. Lolu uhlobo lwesimila oluvame kakhulu olukhula endlaleni ye-pituitary.

Lesi simila sibangela ukuthi umzimba wethu ukhiqize i-hormone ebizwa ngokuthi i-prolactin eningi kunalokho okufanele. Ngokuvamile, le hormone ye-prolactin ibaluleke kakhulu ekukhuleni kwamabele kwabesifazane kanye nokukhiqizwa kobisi lokuncelisa (ukuncelisa). Kodwa lapho le hormone ikhula, kuvela isimo esibizwa ngokuthi i-hyperprolactinemia, singabangela izinkinga ezahlukene kokubili kwabesifazane nabesilisa.

Ingabe zikhona izinhlobo ze-prolactinoma?

Yebo, la mantongomane ahlukaniswe ngezinhlobo ezimbili eziyinhloko ngokusekelwe kusayizi wawo. Ukuze uqonde lokhu, bheka ithebula elingezansi.

Ziyini izimpawu zalokhu?

Izimpawu zincike enanini le-hormone ye-prolactin ekhiqizwayo kanye nobukhulu besimila. Ake sibone ukuthi ziyini lezi zimpawu.

Abesifazane banamathuba amaningi okubona lesi simo kusenesikhathi ngenxa yezimpawu ezifana nokushintsha komjikelezo wabo wokuya esikhathini noma ukuphuma kwesisu emabeleni. Kodwa-ke, abantu abaphuza amaphilisi okuvimbela inzalo noma ezinye izindlela zokwelapha ngama-hormone bangase bangaziboni lezi zimpawu. Futhi, izimpawu zingase zibambezeleke kwabesifazane nabesilisa abaye badlula esikhathini sokuya esikhathini, okungase kubambezele ukuxilongwa.

Iyini imbangela yalokhu?

Eqinisweni, abacwaningi abakayitholi imbangela ethile ye-Prolactinoma. Esikhathini esiningi, yenzeka ngezikhathi ezithile, ngaphandle kwesizathu esithile. Kodwa-ke, ezinye izimo zofuzo zingandisa ingozi.

• "I-Multiple endocrine neoplasia (MEN) uhlobo 1"
• `Uhlobo LWAMADODA 4`
• ``I-Familial isolated pituitary adenomas (FIPA)''

Ukuthola kanjani lokhu, Dokotela?

Udokotela wakho uzoqala ngokubheka izimpawu zakho kanye nomlando wezokwelapha ngokucophelela. Ngemuva kwalokho, bazokwenza ukuhlolwa ngokomzimba. Bangase batuse ukuhlolwa okuningana ukuqinisekisa ukuxilongwa.

• Ukuhlolwa kwegazi le-prolactin: Lokhu ukuhlolwa okuyisisekelo kakhulu. Uma lokhu kuhlolwa kuqinisekisa ukuthi amazinga akho e-prolactin aphezulu kakhulu kunokuvamile, uzothunyelwa ukuze uhlolwe okwengeziwe ukuze kuhlolwe isimila.
• I-MRI noma i-CT scan: Lezi skeni zingabonisa ngqo ukuthi kukhona yini isimila se-pituitary nokuthi, uma kunjalo, sikhulu kangakanani. Odokotela bavame ukuncoma i-MRI scan.
• Ukuhlolwa kwegazi kwezinga le-testosterone: Uma uyindoda, udokotela wakho angase futhi akuncome ukuthi uhlole amazinga akho e-testosterone.

Uma lesi sifo siqinisekiswa, kunganconywa ukuthi uhlole amazinga amanye ama-hormone ku-pituitary gland bese uhlolwa amehlo ngudokotela wamehlo ukuze ubone ukuthi umbono wakho uthintekile yini uma unesimila esikhulu (i-macroprolactinoma).

Yiziphi izindlela zokwelapha lokhu?

Izindaba ezinhle ukuthi kunezindlela zokwelapha ezisebenza kahle kakhulu kulokhu. Ezimweni eziningi, lesi simo singalawulwa ngemithi.

Imithi (izidakamizwa)

Odokotela bavame ukunikeza imithi ebizwa ngokuthi ama-dopamine agonists. Le mithi inganciphisa i-prolactinoma futhi ibuyisele amazinga e-prolactin esimweni esijwayelekile.

• I-Cabergoline ne-Bromocriptine: Lena imithi emibili eyinhloko esetshenziswayo. Kulawa, i-cabergoline iyindlela yokuqala yokukhetha odokotela ngoba isebenza kahle futhi inemiphumela emibi embalwa.
• Imiphumela emibi: Le mithi ingabangela imiphumela emibi emincane njengesicanucanu, ukuhlanza kanye nesiyezi.
• Isikhathi sokwelashwa: Ukuze uvimbele isimila ukuthi singabuyi, kuzodingeka uthathe lo muthi njalo okungenani iminyaka emibili . Ngemva kweminyaka emibili, uma amazinga akho e-prolactin esebuyele esimweni esijwayelekile futhi isimila singasabonakali kuma-scan, udokotela wakho uzonciphisa kancane kancane umthamo womuthi futhi ekugcineni awuyeke.

Ukuhlinzwa

Ukuhlinzwa akudingeki kakhulu. Lokhu kwenzeka ezimweni ezinjengalezi:

• Uma umuthi unemiphumela emibi kakhulu.
• Uma isimila singanciphi ngemithi.
• Uma lo muthi usabela kweminye imithi oyithathayo.
• Uma unesimila esikhulu futhi udinga ukusisusa ngaphambi kokuzama ukukhulelwa.

Kunezinhlobo ezimbili zokuhlinzwa.

1. Ukuhlinzwa kwe-transsphenoidal: Lokhu kuyindlela yokuhlinzwa evame kakhulu. Lapha, isimila sisuswa ngokusikwa okuncane ngaphakathi kwekhala noma ngaphansi kodebe olungaphezulu.

2. Ukuhlinzwa kwe-Transcranial: Uma isimila sikhulu kakhulu, isimila sisuswa ngembobo encane ekhanda.

Ukwelashwa ngemisebe

Ukwelashwa ngemisebe kuyindlela yesithathu lapho umdlavuza ungasabeli emithini noma ekuhlinzweni. Lokhu futhi kuyindlela yokwelapha engavamile kakhulu.

Iyini inhloso yalesi sifo?

Umbono we-prolactinoma muhle kakhulu. Ngokwelashwa kwezokwelapha, abantu abane kwabahlanu abanezimila ezincane bangakwazi ukwenza amazinga abo e-prolactin abe ngcono futhi isimila singancipha.

Ukuhlinzwa kuvame ukuphumelela. Uma kwenziwa udokotela ohlinzayo onolwazi, amazinga e-prolactin angabuyiselwa esimweni esijwayelekile kubantu abangaba ngu-90% abanezimila ezincane kanye nabantu abangu-50% abanezimila ezinkulu.