Ngezinye izinsuku sizizwa sijabule kakhulu, kodwa ngezinye izinsuku sizizwa sidabukile futhi sithukuthele ngisho nangezinto ezincane kakhulu. Wake wazibuza ukuthi kungani lokhu kwenzeka? Omunye wabalingiswa abaphambili ngemuva kokuvela nokuhamba kwale mizwa yi-chemical messenger esebuchosheni bethu ebizwa ngokuthi 'i-Serotonin'. Ngakho-ke, namuhla sizoxoxa ngokuthi iyini le serotonin, ukuthi ibaluleke kangakanani empilweni yethu, nokuthi kwenzekani uma iba phansi kakhulu.
Iyini ngempela i-Serotonin?
Kalula nje, i-serotonin iyikhemikhali ethwala imiyalezo phakathi kwamangqamuzana ezinzwa ebuchosheni bethu. Lokhu sikubiza ngokuthi i-neurotransmitter. Cabanga ukuthi ubuchopho bethu buyidolobha elikhulu. Le serotonin isebenza 'njengomthumeli' othwala imiyalezo esuka kwenye indawo iye kwenye kuleli dolobha.
Kodwa into emangalisayo ukuthi, nakuba i-serotonin ikhiqizwa kakhulu ebuchosheni, cishe u-90% we-serotonin iyonke emizimbeni yethu itholakala ohlelweni lwethu lokugaya ukudla (amathumbu) kanye nama-platelet egazi.
Yiziphi izinzuzo ze-serotonin emzimbeni wethu?
I-Serotonin ihilelekile emisebenzini eminingi emizimbeni yethu. I-Serotonin ithinta ngqo noma ngokungaqondile iningi lamaseli ayizigidi ezingu-40 ebuchosheni bethu.
Ngokuyinhloko, i-serotonin ithinta:
- Isimo Sengqondo: I-Serotonin isisiza ukuthi sihlale sijabule futhi sizolile. Yingakho abanye beyibiza ngokuthi 'i-hormone yenjabulo.'
- Ukulala: I-Serotonin isiza ukugcina iwashi lomzimba elilawula ukulala kwethu nokuvuka kwethu.
- Isifiso sokudla: Lokhu kuhlobene nezinto ezifana nokuzizwa ulambile nokuzizwa usuthi ngemva kokudla.
- Isifiso socansi kanye nomsebenzi: I-Serotonin nayo inethonya emizweni yocansi.
- Inkumbulo nokufunda: Lokhu kubalulekile ekukhumbuleni izinto nasekufundeni izinto ezintsha.
Ngaphezu kwalokho, i-serotonin ithinta nokusebenza kwenhliziyo yethu, imisipha, kanye nezinye izinhlelo zama-hormone emzimbeni. Abacwaningi bathole ukuthi ukungasebenzi kahle kwenethiwekhi ye-serotonin kungathinta ukukhiqizwa kobisi komama abancelisayo kanye nesimo esibizwa ngokuthi i-sudden infant death syndrome (SIDS).
Ubudlelwano phakathi kwe-serotonin nokucindezeleka
Abantu abaningi baye bezwa ukuthi ukucindezeleka kwenzeka lapho amazinga e-serotonin ehla. Kukhona iqiniso elithile kulokhu, kodwa indaba iyinkimbinkimbi kakhulu kunalokho.
Abacwaningi bakholelwa ukuthi ukungalingani kwamazinga e-serotonin ebuchosheni kungaholela ekucindezelekeni, ekukhathazekeni, ekuhlaselweni uvalo, entukuthelweni enamandla, kanye nesifo sokuzibamba esingapheli. Kunezinto eziningana ezingabangela lokhu kungalingani:
- Amangqamuzana obuchopho awakhiqizi i-serotonin eyanele .
- Izindawo ezinciphile zama-receptor ezingabamba i-serotonin ekhiqizwayo.
- I-Serotonin ayikwazi ukufinyelela kahle kula ma-receptor .
- Ukuntuleka kwe-tryptophan, isithako esiyisisekelo esidingekayo ekwenzeni i-serotonin.
Into ebalulekile ukuthi abukho ubuchwepheshe okwamanje bokukala amazinga e-serotonin ebuchosheni bomuntu ophilayo. Ngakho-ke, akufakazelwa ngokuphelele ukuthi ukucindezeleka kubangelwa yi-serotonin ephansi. Kungenzeka ukuthi ukucindezeleka kuvela ngenxa ye-serotonin ephansi, noma kungenzeka ukuthi amazinga e-serotonin anciphe lapho ukucindezeleka kuvela.
Eminye imithi yokucindezeleka, njenge -SSRIs (selective serotonin reuptake inhibitors) kanye ne-SNRIs (serotonin kanye ne-norepinephrine reuptake inhibitors), isebenza ngokwandisa amazinga e-serotonin ebuchosheni. Nakuba le mithi iboniswe ukuthi inciphisa izimpawu, akucaci kahle ukuthi isebenza kanjani. Ngakho-ke, ungalokothi usebenzise le mithi ngaphandle kweseluleko sikadokotela wakho.
Ingabe ukudla nokuzivocavoca kungashintsha amazinga e-serotonin?
Umphumela wokudla nokuphuza
Njengoba ukudla ukudla okune-calcium eningi kukhulisa amazinga e-calcium egazini, akukho ukudla okwandisa i-serotonin ngqo. Kodwa-ke, kukhona ukudla okungakhulisa i-amino acid tryptophan, okuyisithako esidingekayo ukwenza i-serotonin.
Ukudla okucebile ngamaprotheni njengenyama, inhlanzi, inkukhu, ubisi, ushizi, namantongomane kuphezulu ku-tryptophan. Kodwa ngokumangazayo, ngemva kokudla ukudla okucebile ngamaprotheni, amazinga akho e-tryptophan ne-serotonin egazini ayancipha. Kungani kunjalo? Isizathu siwukuthi uma udla amaprotheni, amanye ama-amino acid amaningi ancintisana ne-tryptophan ukuze angene ebuchosheni. Kufana nokuminyana kwezimoto emgwaqweni. Ngakho-ke kuncane kakhulu isikhala se-tryptophan sokungena ebuchosheni.
Kodwa-ke, uma udla ukudla okucebile ngama-carbohydrate njengelayisi, isinkwa, noma amazambane, umzimba wakho ukhiqiza i-insulin. Le insulin idonsa wonke lawo ma-amino acid ancintisanayo emzimbeni wakho, kodwa ivula indlela yokuthi i-tryptophan ingene ebuchosheni bakho. Lokhu kwandisa amazinga e-serotonin ebuchosheni bakho.
Futhi, ukudla ukudla okucebile ngevithamini B6 kusiza ukusheshisa ukuguqulwa kwe-tryptophan ibe yi-serotonin.
Umphumela wokuzivocavoca
Ukuzivocavoca umzimba kungenye yezinto ezinhle kakhulu ongazenza ukuze uthuthukise imizwa yakho. Ezinye izifundo zibonise ukuthi ukuzivocavoca njalo kuyindlela yokwelapha ukucindezeleka esebenza kahle njengemithi noma ukwelulekwa.Ucwaningo olusha luthole ukuthi ngisho nemizuzu engama-40 yokuzivocavoca ingaba nomthelela osheshayo esimweni sengqondo. Kodwa-ke, akukacaci ukuthi ukuzivocavoca kwenza kanjani lokhu. Abanye bakholelwa ukuthi kuthinta amazinga e-serotonin.
Ingabe i-serotonin ithinta abesifazane nabesilisa ngendlela efanayo?
Ucwaningo lubonise ukuthi amadoda ane-serotonin eningi kancane emizimbeni yawo kunabesifazane. Kodwa umehluko omkhulu usekutheni asabela kanjani lapho amazinga e-serotonin ehla.
Uma amazinga e-serotonin encishisiwe, amadoda aba namawala , kodwa awazizwa ecindezelekile. Kodwa imizwa yabesifazane iyehla ngokuzumayo , futhi baba nokuqapha nokuqapha okukhulu . Lona umuzwa ohlotshaniswa nokucindezeleka. Lokhu kungaba yingakho izinkinga zokukhathazeka nemizwa zivame kakhulu kwabesifazane, kanti umlutha wotshwala, i-ADHD, nezinkinga zokulawula amawala zivame kakhulu kwabesilisa.
| Umthelela | Amadoda | Owesifazane |
|---|---|---|
| Impendulo uma i-serotonin iphansi | Ukuba nolaka | Ukushintshashintsha kwemizwa, ukuqaphela (Qaphela) |
| Izinkinga ezivamile | Ukulutheka kotshwala, i-ADHD, izinkinga zokulawula ukushukuma komzimba | Ukukhathazeka, izinkinga zemizwa (njengokucindezeleka) |
Futhi, ngenxa yethonya lama-hormone abesifazane, umsebenzi we-serotonin ungashintsha ngaphambi kokuya esikhathini, ngemva kokubeletha, kanye nangesikhathi sokunqamuka kokuya esikhathini. Yingakho ukushintshashintsha kwemizwelo kubonakala ngalezi zikhathi.
Isimo esiyingozi: Iyini i-serotonin syndrome?
Imithi yokucindezeleka efana ne-SSRI ngokuvamile iphephile. Kodwa-ke, kunemiphumela emibi engavamile kodwa eyingozi kakhulu .Umphumela ongemuhle yi-serotonin syndrome, eyenzeka lapho amazinga e-serotonin ebuchosheni ephakama kakhulu.
Lokhu kuvame ukwenzeka uma imithi emibili noma ngaphezulu ethinta i-serotonin ithathwa ngesikhathi esisodwa. Isibonelo, uma uthatha i-SSRI yokucindezeleka kanye ne-triptan yobuhlungu bekhanda, ungathola i-serotonin egcwele ngokweqile. Kukhona futhi ingozi yokuthi lokhu kwenzeke ngemikhiqizo yamakhambi njenge-St. John's Wort kanye ne-SSRIs. Kungenzeka futhi ngemithi efana ne-Ecstasy kanye ne-LSD.
Izimpawu zingavela zingakapheli imizuzu kuya emahoreni okuqala umuthi noma ukwandisa umthamo. Zihlanganisa:
- Ukungaphumuli, ukucasuka
- Ukubona izinto ezingabonakali (i-Hallucinations)
- Ukushaya kwenhliziyo
- Ukushisa komzimba okwenyukayo kanye nokujuluka ngokweqile
- Ukulahlekelwa yibhalansi yomzimba
- Ukuqhaqhazela kwemisipha, ukuqina
- Isicanucanu, ukuhlanza, isifo sohudo
- Ukunyuka nokwehla kwengcindezi yegazi ngokuzumayo
Lesi yisimo esiyingozi kakhulu futhi sibhekwa njengesimo esiphuthumayo sezokwelapha . Uma wena noma othile omaziyo eba nesinye salezi zimpawu ngemuva kokuthatha umuthi, hamba uye egumbini lezimo eziphuthumayo esibhedlela esiseduze (ETU) ngokushesha.
Umlayezo Wokuya Nawe Ekhaya
- I-Serotonin iyikhemikhali yobuchopho ebaluleke kakhulu elawula imizwa yakho, ubuthongo kanye nesifiso sokudla.
- Nakuba amazinga aphansi e-serotonin kukholakala ukuthi ahlobene nokucindezeleka, akukaze kutholakale ukuthi yiyona imbangela kuphela.
- Ukudla okunomsoco (ikakhulukazi okunama-carbohydrate) kanye nokuzivocavoca njalo kuzokusiza ukugcina isimo sakho sengqondo sisesimweni esihle ngokwemvelo.
- Ungalokothi uxube futhi usebenzise imithi, ikakhulukazi leyo ethinta i-serotonin, ngaphandle kweseluleko sikadokotela wakho.
- Uma uba nezimpawu ezifana nokungahlaliseki, umkhuhlane ophakeme, nokudideka ngemva kokuqala umuthi omusha, kungaba yisimo esiyingozi esibizwa ngokuthi i-serotonin syndrome. Yiya egumbini lezimo eziphuthumayo esibhedlela (ETU) ngokushesha.
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