Ukuntuleka kwe-testosterone? Ake sifunde konke mayelana nokwelashwa kwe-TRT ngamagama alula (Ukwelashwa Kokufaka I-Testosterone - TRT)

Ingabe ubulokhu uzizwa ukhathele kakhulu, ungenasithakazelo kunoma yini, futhi ungenawo amandla owawunawo muva nje ? Ngezinye izikhathi sicabanga ngalokhu njengezimpawu ezivamile zokuguga, kodwa ukwehla kwe-testosterone, enye yama-hormone ayinhloko emzimbeni wendoda, nakho kungaba yimbangela yalokhu. Ngakho-ke namuhla, ake sixoxe ngokwelashwa kokushintsha kwe-testosterone, noma i-TRT (Testosterone Replacement Therapy), okuwukwelashwa okunikezwayo lapho amazinga e-testosterone ephansi. Ake siqonde ukuthi iyini, ubani oyidingayo, nokuthi yiziphi izinzuzo nezingozi.

Kuyini i-TRT? Ake sikuqonde kalula.

Kalula nje, i-TRT iwukwelashwa okubuyisela amazinga e-testosterone kwabesilisa abanamazinga aphansi e-testosterone ngenxa yezizathu zezokwelapha. Kufana nokunikeza imizimba yethu into entula ngaphandle.

Cabanga ngale ndlela, njengalapho unezinga eliphansi le-iron, sithatha amaphilisi e-iron. Kodwa lokhu kufanele kwenziwe kuphela ngaphansi kokuqondisa kukadokotela. Ngoba lokhu kwelashwa kungaba nezinzuzo kanye nezingozi ezithile. Ngakho-ke, wena nodokotela wakho nizonquma ndawonye ukuthi lokhu kulungile yini kuwe noma cha.

Ubani ngempela odinga lokhu kwelashwa?

Lona umbuzo obaluleke kakhulu. I-TRT akuyona indlela yokwelapha enganikezwa wonke umuntu. Ngisho nezikhungo ezifana ne-Food and Drug Administration (FDA) e-United States zivumile lokhu kwelashwa kuphela kulabo abanamazinga aphansi e-testosterone ngenxa yesimo sezokwelapha esiqinisekisiwe ngokwezokwelapha . Lesi simo sisibiza ngokuthi `(Male Hypogonadism)`.

Yiziphi izimbangela ze-`(Hypogonadism)`?

Kunezitho ezintathu eziyinhloko ezihilelekile enqubweni yokukhiqizwa kwe-testosterone. Noma yimuphi umonakalo noma ukungasebenzi kahle kwanoma yikuphi kwalokhu kungaholela emazingeni aphansi ama-hormone.

• Amasende: Indawo eyinhloko yokukhiqizwa kwe-testosterone.
• Indlala ye-pituitary: Le ndlala ebuchosheni itshela amasende ukuthi akhiqize ama-hormone.
• I-Hypothalamus: Enye ingxenye yobuchopho elawula ukusebenza kwendlala ye-pituitary.

Cabanga nje, lezi zitho zomzimba zingalimala ngokwelashwa ngamakhemikhali noma ngemisebe okunikezwa isiguli somdlavuza. Noma le nkinga ingavela ngenxa yesimo sofuzo.

Yini okudingeka uyazi ngaphambi kokuqala i-TRT?

Ngaphambi kokuqala i-TRT, udokotela wakho uzoqinisekisa ukuthi unamazinga aphansi e-testosterone nokuthi lokhu kwelashwa kuphephile kuwe. Bazokwenza okulandelayo:

1. Khuluma ngomlando wakho wezokwelapha: Buza ngezinye izifo onazo, imithi oyiphuzayo, kanye nomlando wezokwelapha womndeni.

2. Uhlola umzimba: Uhlola umzimba wonke.

3. Oda ukuhlolwa kwegazi okuningana: Lokhu kubaluleke kakhulu.

• Ukuhlolwa kwe-testosterone kabili ekuseni: Amazinga e-testosterone aphezulu kakhulu ekuseni, ngakho-ke kuthathwa amasampula egazi amabili ekuseni ukuze kutholakale ukufundwa okunembile kakhulu.
• I-Hemoglobin kanye ne-Hematocrit: Bona inani lamaseli abomvu egazini.
• Ukuhlolwa kokusebenza kwesibindi: Hlola ukuthi isibindi siphilile yini.
• Ukuhlolwa kwe-hormone ye-luteinizing: Thola umbono ngokusebenza kwe-pituitary gland.
• Ukuhlolwa kwe-PSA (i-prostate-specific antigen): Funda ngempilo ye-prostate.
• Ukuhlolwa kwe-hormone ye-prolactin.

Ngemva kokucabangela konke lokhu, udokotela uzothatha isinqumo sokugcina sokuthi i-TRT ikulungele yini noma cha.

Lokhu kwelashwa kusebenza kanjani?

Ukwelashwa kwe-TRT kuhilela ukunikeza umzimba wakho i-testosterone yokwenziwa ukuze kulawulwe amazinga ama-hormone. Lokhu kungasiza ekuthuthukiseni izimpawu zokuntuleka kwe-testosterone (njengokuncipha kwesifiso sobulili kanye nokulahlekelwa amandla).

Kodwa nansi into ebalulekile okufanele uyiqonde. I-TRT ayilaphi imbangela eyinhloko yama-hormone akho aphansi. Lokho ekwenzayo ngempela ukuthi, ngokukunika ama-hormone avela ngaphandle, amasende akho acabanga ukuthi, "O, asisadingi ukwenza ama-hormone," bese eyeka ukuwakhiqiza ngokwemvelo. Lokho kusho ukuthi kufanele uqhubeke nokuthatha umuthi ukuze ugcine amazinga ama-hormone ajwayelekile. Uma uyeka ukuthatha umuthi, kuzothatha isikhathi ukuthi umzimba wakho ufunde ukukhiqiza i-testosterone futhi.

Yiziphi izindlela ezahlukene ze-TRT?

Ngenhlanhla, kunezindlela ezingaphezu kweyodwa zokuthola i-TRT. Ungakhetha indlela efanelana nendlela yakho yokuphila kanye nokulula kwakho ngokukhuluma nodokotela wakho.

Ngemva kokuqala ukwelashwa, udokotela wakho uzohlola njalo amazinga akho ama-hormone kanye nokunye ukuhlolwa kwegazi ukuze abone ukuthi ukwelashwa kubangela ezinye izinkinga zempilo.

Yiziphi izinzuzo ze-TRT?

Uma inikezwa ngendlela efanele futhi kumuntu ofanele, i-TRT ingaba wusizo olukhulu. Ingasiza ekunciphiseni izimpawu zokuntuleka kwe-testosterone ngezinga elikhulu.

• Ukwanda kwemisebenzi yocansi kanye nesithakazelo: Lokhu kuyinzuzo enkulu kubantu abaningi.
• Ukwanda kwemisipha: Kusiza umzimba ukuba uqine futhi uqine.
• Ukwanda kwamaminerali emathanjeni: Amathambo ayaqina futhi mancane amathuba okuphuka.
• Isimo sengqondo esithuthukisiwe: Ukukhathazeka nokucasuka kwangaphambilini kunciphile, futhi ungase uzizwe uqabulekile.
• Kwandisa amandla nokuqina: Kukusiza ukuthi uhlale umatasa usuku lonke.
• Ukuzizwa kahle sekukonke.

Ingabe kufanele futhi siqaphele imiphumela emibi?

Njenganoma yimuphi umuthi, i-TRT ingaba nemiphumela emibi. Akuwona wonke umuntu oyitholayo, kodwa kubalulekile ukuyiqaphela.

• Isikhumba esinamafutha noma esinama-acne.
• Ukuvuvukala endaweni yeqakala (ngenxa yokugcinwa koketshezi okuncane emzimbeni).
• Ubunzima bokuchama ngenxa yokukhuthazwa yi-prostate.
• Amabele amakhulu noma abuhlungu (i-Gynecomastia).
• Ukuwohloka kwe-apnea yokulala.
• Amasende amancane.
• Uma usebenzisa izimonyo zesikhumba, ungase ube nokungezwani komzimba nesikhumba.
• Ukwehla kwenani lesidoda ngakho-ke kunciphisa ukuzala. Lokhu kubaluleke kakhulu. Uma uhlela ukuba nezingane, kufanele ucabange kabili futhi ukhulume nodokotela wakho ngalokhu ngaphambi kokuqala i-TRT.

Ngaphezu kwalokho, kunezinguquko eziningana ezingabonakala ekuhlolweni kwegazi:

• Amazinga e-PSA akhuphukayo.
• Ukwanda kwenani lamaseli abomvu egazi. Lokhu kungenza igazi libe likhulu futhi kwandise ingozi yokuqhekeka kwegazi.

Kuthatha isikhathi esingakanani ukubona imiphumela?

Lokhu kuyahlukahluka kuye ngomuntu nomuntu. Abanye abantu baqala ukuzwa izinguquko emzimbeni nasengqondweni yabo zingakapheli amasonto ambalwa. Odokotela bavame ukuhlola amazinga e-testosterone futhi cishe inyanga ngemva kokuqala ukwelashwa ukuze babone umphumela ogcwele.

Uma izimpawu zakho zingakathuthuki ngemva kwezinyanga ezi-3 kuya kweziyi-6, udokotela wakho angase akuncome ukuthi uyeke ukwelashwa. Lokhu kungenxa yokuthi izimpawu zakho kungenzeka zingabangelwa yi-testosterone ephansi.

Ubani okungafanele asebenzise i-TRT?

Kubantu abanezimo ezithile zezokwelapha, ukusebenzisa i-TRT kungenza lezo zimo zibe zimbi kakhulu. Ngakho-ke, i-TRT ayifanele labo abanalezi zimo.

• Ukwehluleka kwenhliziyo okukhulu okungalashwanga.
• I-apnea yokulala engapheli engelashwa.
• Uma uke waba nesifo senhliziyo noma isifo sohlangothi ezinyangeni eziyisithupha ezedlule.
• Amazinga aphezulu amaseli abomvu egazini.
• Ukuba nomdlavuza wendlala.
• Ukuba neqhubu elingahlolwanga ku-prostate.
• Umdlavuza webele wabesilisa.

Ingabe i-TRT iphephile ngempela? Ake sixoxe ngezingozi.

Lokhu kuyinkinga kubantu abaningi. Njengoba kushiwo ngaphambili, i-TRT ngokuvamile ibhekwa njengephephile kubantu abangenazo izimo ezifana nomdlavuza wendlala noma isifo senhliziyo, inqobo nje uma ithathwa ngaphansi kokuqondisa kukadokotela.

Kodwa-ke, kusenokuntuleka kocwaningo olukhulu ngalokho okwenzekayo uma i-TRT ithathwa isikhathi eside, njengamashumi eminyaka. Imiphumela yezinye zezifundo ezikhona iyaphikisana.

Isibonelo, ezinye izifundo ziphakamisa ukuthi i-TRT inciphisa ingozi yesifo senhliziyo ngokuhamba kwesikhathi. Ezinye ziphakamisa ukuthi iyandisa ingozi. Isibonelo, ucwaningo olukhulu ngo-2024 luthole ukuthi ukusetshenziswa isikhathi eside kwejeli ye-testosterone akukhulisi ingozi yesifo senhliziyo. Kukhona nemibono ephikisanayo mayelana nengozi yokuqhekeka kwegazi emithanjeni (i-venous thromboembolism).

Ngenxa yazo zonke lezi zizathu, udokotela wakho uzohlola ngokucophelela isimo sakho sempilo bese enquma ukuthi i-TRT iphephile yini kuwe.

Kunini lapho udinga ukubonana nodokotela wakho?

Ngemva kokuqala i-TRT, kuzodingeka ubone udokotela wakho ngezikhathi ezithile futhi uhlolwe igazi. Udokotela wakho uzokunikeza ishejuli. Ngaphezu kwalokho, bona udokotela wakho ngalezi zikhathi futhi.

• Uma izimpawu zakho zingathuthuki naphezu kokwelashwa.
• Uma imiphumela emibi ikukhathaza.
• Uma ufuna ukuzama indlela ehlukile ye-TRT.
• Uma ucabanga ukumisa i-TRT.
• Ukuthatha i-TRT kungaba yingozi uma unesifo esisha.

Uma izimpawu ze-testosterone ephansi zithinta impilo yakho, akuyona into ongayibekezelela nje. I-TRT ingaba inketho enhle kuwe. Kodwa isinqumo kufanele senziwe nguwe nodokotela wakho, sihlola zonke izinzuzo nezingozi. Unganqikazi ukukhuluma nodokotela wakho nganoma yimiphi imibuzo noma ukukhathazeka ongase ube nakho.