Kuvamile ukuzizwa wesaba futhi ukhathazekile kancane lapho wena noma othandekayo wakho uqala ukwelashwa komdlavuza. Lokho kwesaba kunganda, ikakhulukazi uma uzwa igama elithi 'chemotherapy'. Kodwa ungesabi nhlobo. Ukuze le nqubo yokwelapha iphumelele, kumele siqale sibe nolwazi oluhle ngalo muthi. Ngemuva kwalokho singabhekana kahle nalolu hambo. Namuhla sikhuluma ngomuthi owodwa onjalo wokulwa nomdlavuza, iThioguanine (6-TG).
Uhlobo luni lomuthi iThioguanine (6-TG)?
Kalula nje, i-Thioguanine iyisidakamizwa esilwa nomdlavuza . Odokotela bayibiza ngokuthi umuthi 'we-chemotherapy'. Umsebenzi wayo oyinhloko ukuvimba ukukhula kwamaseli omdlavuza ahlukana ngokushesha emzimbeni futhi awabhubhise.
Lo muthi usetshenziselwa ngqo ukwelapha izinhlobo ezithile ze-leukemia , okuyizimila zomdlavuza zamaseli egazi. Ngezinye izikhathi, udokotela wakho angase akunike lo muthi kwezinye izimo. Ngakho-ke uma unemibuzo mayelana nokuthi kungani unikezwe lo muthi, kungcono ukubuza udokotela wakho.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokuqala ukwelashwa kwe-Thioguanine, kubaluleke kakhulu ukwazisa udokotela wakho ngomlando wakho wezempilo ophelele. Ngoba kudingeka siqaphele kakhulu lapho sisebenzisa lo muthi onezimo ezithile zempilo. Uma unezinye zalezi ezilandelayo, qiniseka ukuthi usitshela ngakho.
| Isimo/iqiniso lempilo | Kungani kufanele wazise udokotela? |
|---|---|
| Ukutheleleka kwamanje (ikakhulukazi okubangelwa amagciwane njenge-chickenpox kanye ne-herpes) | Ngenxa yokuthi lo muthi wehlisa amasosha omzimba, izifo ezikhona zingase zibe zimbi kakhulu. |
| Isifo sesibindi | Ngenxa yokuthi lo muthi ucutshungulwa yisibindi, ungaba nemiphumela emibi ezifweni zesibindi. |
| Ukwehla kwenani lamaseli egazi (amaseli amhlophe egazi, amaseli abomvu egazi, ama-platelet) | I-Thioguanine inganciphisa kakhulu ukukhiqizwa kwamangqamuzana egazi, okungaba yingozi uma inani lamangqamuzana egazi lakho selivele liphansi. |
| Ukuntuleka kwe-TPMT (ukuntuleka kwe-Thiopurine methyltransferase) | Lesi yisimo sofuzo. Abantu abangenalo leli enzyme bangase babe nokuqongelela kwe-Thioguanine emizimbeni yabo, okwandisa imiphumela emibi. |
| Ukungezwani komzimba | Kubalulekile ukwazisa udokotela wakho uma une-allergies ku-Thioguanine noma eminye imithi noma ukudla. |
| Ukuzama ukukhulelwa, ukukhulelwa, noma ukuncelisa | Lo muthi ungabangela umonakalo omkhulu enganeni engakazalwa, ngakho-ke kubalulekile ukukhuluma ngakho. |
Ngingawusebenzisa kanjani umuthi?
Indlela yokusebenzisa lo muthi ilula kakhulu, kodwa ibaluleke kakhulu.
- Gwinya iphilisi ngengilazi yamanzi , njengoba kuqondiswe kudokotela wakho.
- Thatha umuthi wakho nsuku zonke, njengoba nje udokotela wakho ekutshelile, ngesikhathi otshelwe ngaso. Ungayeki ama-aphoyintimenti.
- Ungayeki ukuthatha umuthi noma ushintshe umthamo nganoma yisiphi isizathu ngaphandle kweseluleko sikadokotela wakho.
- Uma unikeza izingane lo muthi, khuluma nodokotela wezingane ngakho bese ulandela imiyalelo yabo.
Qaphela: Uma ucabanga ukuthi uthathe imithi eminingi kunaleyo oyinikezwe udokotela, ungalibali. Shayela ngokushesha i-National Poisons Information Centre e-Colombo National Hospital noma uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma uphuthelwa umthamo, ungakhathazeki. Yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esihleliwe. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa.Lokho kusho ukuthi ungaphuzi umthamo ophindwe kabili ukuze ubuyisele umthamo okhohliwe. Uma uhlanza ngemva kokuthatha umuthi, cela iseluleko kudokotela wakho mayelana nokuthi yini okufanele uyenze ngokulandelayo.
Eminye imithi engase ihlangane nalo muthi
Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa imithi kadokotela, imithi ethengiswa ngaphandle kwemithi kadokotela, amavithamini, imithi yamakhambi, ngisho nezithasiselo. Eminye imithi ingasebenzisana ne-Thioguanine futhi yandise imiphumela emibi noma ishintshe indlela esebenza kahle ngayo.
Qaphela kakhulu ngemithi elandelayo:
- I-Busulfan (esinye isidakamizwa sokwelapha umdlavuza)
- Imithi evimbela ukujiya kwegazi (isib. i-Warfarin)
- Imithi yokwandisa inani lamaseli egazi (isb. i-filgrastim)
- Izidakamizwa ezifana neMesalamine, i-Olsalazine, i-Sulfasalazine, ne-Balsalazide
- Imithi yokugoma yanoma yiluphi uhlobo
Isexwayiso esikhethekile: Ungathathi imithi yokunciphisa ubuhlungu ethengwa ngaphandle kwemithi kadokotela efana ne-aspirin, i-acetaminophen, ne-ibuprofen ngaphandle kokubonisana nodokotela wakho. Le mithi ingacindezela izimpawu ezifana nomkhuhlane. Kubalulekile ukuqaphela umkhuhlane kusenesikhathi, njengoba kungaba uphawu lokuqala lokutheleleka lapho uthatha i-Thioguanine.
Izinto okufanele uzicabangele lapho uphathwa
Njengoba i-chemotherapy ithinta amangqamuzana omdlavuza kanye namaseli anempilo, kuyinto evamile ukuzizwa ungakhululekile futhi ukhathele. Kodwa-ke, ungayeki ukwelashwa kuze kube yilapho udokotela wakho ekuyala ngenxa yalokhu kungakhululeki.
- Zivikele ezifweni: Lo muthi wehlisa amasosha omzimba wakho, ngakho-ke unamathuba amaningi okugula. Ngakho-ke, gwema ukuya ezindaweni ezinabantu abaningi nokuxhumana nabantu abagulayo (labo abanomkhuhlane noma umkhuhlane) ngangokunokwenzeka. Uma uzwa izimpawu ezifana nomkhuhlane, umkhuhlane, umphimbo obuhlungu, noma ubuhlungu bomzimba , ungaziphilisi bese utshela udokotela wakho ngokushesha.
- Qaphela ukopha: Ingozi yokopha inganda. Ngakho-ke, xubha amazinyo akho kancane. Ungasebenzisi amabhulashi aqinile. Hlola noma yimiphi imivimbo noma amabala amancane abomvu esikhumbeni. Uma ubona into efana naleyo, yazisa udokotela wakho.
- Gwema ukukhulelwa: Lokhu kubaluleke kakhulu. Gwema ukukhulelwa ngokuphelele ngenkathi uthatha lo muthi. Futhi, gwema ukuncelisa ngenkathi uthatha lo muthi. Buza udokotela wakho ngolwazi olwengeziwe ngalokhu.
Yimiphi imiphumela emibi evame kakhulu?
Njenganoma yimuphi umuthi, i-Thioguanine ingabangela imiphumela emibi. Kodwa akuwona wonke umuntu oyitholayo. Eminye ivame kakhulu, kanti eminye ayivamile kakhulu. Into ebalulekile ukwazi ukuthi iyini imiphumela emibi nokuthi yini okufanele uyenze uma ivela.
| Imiphumela emibi ye-Thioguanine (6-TG) | |
|---|---|
| 🚨 Imiphumela emibi edinga ukunakekelwa kwezokwelapha okusheshayo | |
| Izimpawu zokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi, nobunzima bokuphefumula. |
| Izimpawu zokutheleleka | Umkhuhlane, ukubanda, ukukhwehlela, umphimbo obuhlungu, ubuhlungu lapho uchama. |
| Izimpawu zokopha | Ukuphuka kwesikhumba okungachazeki, khomba amabala abomvu ngaphansi kwesikhumba, indle emnyama, kanye negazi emchameni. |
| Izimpawu ze-anemia | Ukukhathala okungajwayelekile, ukudinwa, isiyezi, amehlo aluhlaza okwesibhakabhaka. |
| Izinkinga zesibindi | Ubuhlungu ohlangothini olungaphezulu kwesokudla lwesisu, ukuphuzi kwamehlo noma isikhumba (i-jaundice). |
| Ezinye izimpawu ezinkulu | Izilonda zomlomo, ukuvuvukala kwamaqakala, izinyawo noma isisu, ukukhuluphala ngokuzumayo. |
| 🙂 Imiphumela emibi okufanele ibikwe kudokotela uma iqhubeka | |
| Izinkinga zesistimu yokugaya ukudla | Uhudo, ukulahlekelwa yisifiso sokudla, isicanucanu, nokuhlanza. |
Ungawugcina kanjani umuthi ngendlela efanele?
- Yigcine endaweni ephephile kude nezingane.
- Gcina endaweni eyomile ekamelweni lokushisa (phakathi kuka-15 no-25 degrees Celsius).
- Vikela emswakama. Ngakho-ke gcina ibhodlela lemithi livaliwe kahle.
- Lahla noma yimiphi imithi esiphelelwe yisikhathi.
Umlayezo Wokuya Nawe Ekhaya
- I-Thioguanine umuthi we-chemotherapy osetshenziselwa ukwelapha umdlavuza ofana ne-leukemia.
- Njalo thatha imithi yakho njengoba nje udokotela wakho ekuyalele, ngesikhathi esifanele.
- Tshela udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nemithi yendabuko oyithathayo.
- Uma ubona izimpawu zokutheleleka noma ukopha, njengomkhuhlane, ukuklwebheka, noma ukuklwebheka, yazisa udokotela wakho ngokushesha.
- Gwema ngokuphelele ukukhulelwa nokuncelisa ngenkathi uthatha lo muthi.
- Ungalokothi uyeke ukwelashwa noma ushintshe umthamo ngaphandle kweseluleko sikadokotela.
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