Ingabe uke watholakala une- Primary Biliary Cholangitis ( PBC ) , noma njengoba odokotela beyibiza kanjalo? Uma kunjalo, cishe usuqalile ukwelashwa. Kodwa ingabe ngezinye izikhathi uzizwa sengathi imithi oyithathayo ayisizi kangako njengoba ucabanga, nokuthi lesi sifo sinjalo nje? Kuvamile ukuzizwa ngaleyo ndlela, futhi ungakhathazeki ngakho. Namuhla, sizoxoxa ngokuthi kwenzekani uma ukwelashwa kwakho kwe-PBC kungasebenzi, ukuthi ungakubona kanjani, nokuthi yini okufanele uyenze ngokulandelayo.
Okokuqala, iyini i-PBC ngamagama alula?
Cabanga ngesibindi sethu njengenye yezimboni ezinkulu emzimbeni wethu. Uketshezi olubalulekile olukhiqizwa kule fektri lubizwa ngokuthi 'i-bile'. Le nyongo isisiza ukugaya ukudla esikudlayo. Le nyongo ikhishwa esibindini ngesistimu ebucayi kakhulu yamapayipi amancane ( amapayipi enyongo ).
Esimweni esibizwa ngokuthi i-PBC, isici ohlelweni lwethu lokuzivikela komzimba sihlasela lawa mapayipi e-bile athambile futhi sibangele ukuthi avuvuke ngaphakathi. Kufana nombhobho wamanzi ovalekile. Ngemuva kwalokho, i-bile ayikwazi ukugeleza kahle bese iqala ukuqongelela ngaphakathi kwesibindi.
Ezigabeni zokuqala, kungase kungabi nazimpawu. Kodwa njengoba le nyongo inqwabelana ngokuhamba kwesikhathi, ilimaza amangqamuzana esibindi futhi ibangele izibazi. Uma lesi simo siba sibi kakhulu, sibizwa ngokuthi i-cirrhosis . Uma singelashwa kahle, singaholela nasekuhlulekeni kwesibindi . Yingakho kubaluleke kakhulu ukuqala ukwelashwa ngokushesha okukhulu.
Umuthi wokuqala udokotela awunikezayo - i-UDCA
Uma usuthole ukuthi une-PBC, umuthi wokuqala udokotela wakho avame ukuqala ngawo yi- Ursodeoxycholic acid . Njengoba kunzima ukukhumbula igama elide, sonke siwubiza ngokuthi i-UDCA ngamafuphi.
Lokho okwenziwa yilo muthi we-UDCA ukusiza inyongo eqongeleleke esibindini ukuthi iphume kalula. Lokhu kunciphisa umonakalo esibindini. Kodwa kukhona into eyodwa ebalulekile sonke okudingeka siyiqonde.
Lo muthi we-UDCA awukwazi ukwelapha ngokuphelele i-PBC. Kodwa-ke, ungavimba lesi sifo ukuthi singaqhubeki ngokushesha, ulawule umonakalo esibindini, futhi ukusize uphile impilo evamile.
Kodwa inkinga iwukuthi, lo muthi awusebenzi ngendlela efanayo kuwo wonke umuntu. Abanye abantu abatholi imiphumela abayilindele kuwo.
Wazi kanjani ukuthi umuthi awusebenzi?
Ucwaningo luthole ukuthi cishe abantu abangu-40% abasebenzisa i-UDCA, noma cishe abantu abane kwabayishumi, abatholi izinzuzo ezilindelekile kulo muthi. Inani elincane labantu liba nemiphumela emibi njengokuphazamiseka kwesisu kanye nesifo sohudo, okwenza kube nzima ukuqhubeka nokusebenzisa umuthi.
Uma ukwelashwa kwakho kungasebenzi kahle, ungase uqhubeke nokuba nezimpawu ezifana nalezi noma ube nezimpawu ezimbi kakhulu.
| Isibonakaliso | Indlela okuzwakala ngayo |
|---|---|
| Ukuzizwa njalo kokukhathala okukhulu | Ukuzizwa ungenampilo ngisho nangemva kokulala kahle futhi ungenzi lutho. |
| Ukuklwebha isikhumba | Ukulunywa okungabekezeleleki emzimbeni wonke, ikakhulukazi ebusuku. |
| Ukuphuzi kwesikhumba namehlo | Amhlophe emehlweni nasesikhumbeni aphenduka aphuzi, njengase-jaundice. |
| Amehlo nomlomo owomile | Umlomo owomile njalo kanye nomuzwa wokoma, njengesihlabathi emehlweni. |
| Ubuhlungu ohlangothini oluphezulu kwesokudla lwesisu | Ubuhlungu obungazwakali buvela endaweni yesibindi, okungukuthi, ohlangothini lwesokudla lwesisu, ngaphansi kwezimbambo. |
| Ukuvuvukala kwamalungu kanye nesisu | Ikakhulukazi ukuvuvukala emilenzeni, emaqakaleni, bese kuba yisisu. |
Ubani okungenzeka kakhulu ukuthi angasebenzisi i-UDCA?
Odokotela baqaphele ukuthi abanye abantu bangase bathole imiphumela enciphile evela ku-UDCA. Lokhu kufaka phakathi:
- Abantu asebevele benesifo sokuqina kwesibindi.
- Abantu abanamazinga aphezulu kakhulu ama-enzyme esibindi abizwa ngokuthi i-gamma-glutamyl transferase kanye ne-alkaline phosphatase egazini labo.
- Abesilisa (nakuba i-PBC ivame kakhulu kwabesifazane, ingaba nzima kakhulu kwabesilisa).
- Abesifazane abatholakale benesifo se-PBC ngaphambi kweminyaka engu-45.
Ungakuqinisekisa kanjani lokhu, dokotela?
Ngisho noma izimpawu zakho ziqhubeka, udokotela ngeke anqume ngokushesha ukuthi "umuthi awusebenzi." Kukhona indlela yokwazi ngokuqinisekile.
Uma usuqalile ukwelashwa, udokotela wakho uzokugada njalo. Ngokuvamile bazo-oda ukuhlolwa kwegazi njalo ezinyangeni ezi-3 kuya kwezi-6. Kodwa ngezinye izikhathi kungathatha unyaka ukusho ngokuqinisekile ukuthi lo muthi usebenza ngempela yini kuwe.
Lokhu kuhlolwa kwegazi kubheka kakhulu amazinga e-enzyme yesibindi sakho, ikakhulukazi i-Alkaline Phosphatase (ALP) ne -Bilirubin . Uma la mazinga esephezulu kakhulu kunokujwayelekile ngemva kwezinyanga eziningana zokuthatha i-UDCA, kungaba uphawu lokuthi ukwelashwa akusebenzi njengoba bekulindelekile.
Uma lokho kwenzeka, udokotela wakho angase anqume ukwengeza umuthi omusha ku-UDCA yakho noma akhulume nawe ngenye indlela yokwelashwa.
Ngakho-ke kufanele ngenzeni?
Lena yinto ebaluleke kakhulu okudingeka uyazi kulesi sihloko.
Ukukhuluma ngokukhululekile nangokuthembekile nodokotela wakho.
Uma izimpawu zakho zingathuthuki noma zibonakala ziba zimbi kakhulu, qiniseka ukuthi utshela udokotela wakho ngakho ngesikhathi esizayo lapho umbona. Ungafihli ulwazi, ucabanga ukuthi, "Lokhu kumele kube yinto evamile," noma ucabanga ukuthi kuzomkhathaza udokotela. Yonke into encane ozizwa ibalulekile lapho wenza izinqumo zokwelashwa.
Khumbula, ukuthi umuthi wokuqala awusebenzanga akusho ukuthi usuphelile. Ukwelapha sekuthuthuke kakhulu. Kunezinketho eziningi kanye nemithi emisha yokusiza ukuphatha isimo sakho. Into ebaluleke kakhulu ukuthi wena nodokotela wakho nisebenzisane njengeqembu.
Umlayezo Wokuya Nawe Ekhaya
- I-PBC yisifo esilimaza amapayipi amancane athwala inyongo aye esibindini. Uma ingelashwa kahle, ingaholela ekulimaleni okukhulu kwesibindi ngokuhamba kwesikhathi.
- I-UDCA iyindlela yokwelapha eyinhloko neyokuqala ye-PBC, kodwa ayisebenzi kahle kuwo wonke umuntu.
- Uma izimpawu ezifana nokukhathala njalo, ukulunywa kwesikhumba, kanye nokuphuzi kwamehlo kuqhubeka naphezu kokusebenzisa imithi, kungase kusho ukuthi ukwelashwa akulungile kuwe.
- Ukukhuluma nodokotela wakho ngezimpawu zakho kanye nemizwa yakho kuyinto engcono kakhulu ongayenza empilweni yakho.
- Ngisho noma ukwelashwa okukodwa kungasebenzi, kunezinye izindlela kanye nemithi yokuphatha isimo sakho. Ngakho-ke ungesabi noma ukwethuka.
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