Ingabe i-asthma yakho kunzima ukuyilawula? Ake sifunde ngomuthi wokugomela i-Xolair we-asthma enzima yokungezwani komzimba.

Iningi labantu abane-asthma lingakwazi ukulawula izimpawu zabo nge-inhaler yansuku zonke. Kodwa kwabanye abantu, le i-inhaler yodwa ayanele. Ingabe kunjalo nangawe? Uma une-asthma enzima, futhi imithi yakho evamile ingasizi, kungaba umthwalo wangempela, akunjalo? Kodwa ungakhathazeki. Muva nje, kuye kwethulwa imithi emisha yokwelapha lezi zimo ze-asthma ezinzima. Lezi akuzona izi-inhaler, kodwa imijovo. Omunye wemithi enjalo yi-Xolair.

Isebenza kanjani i-Xolair? Okokuqala, ake siqonde kancane nge-asthma.

Kalula nje, i-asthma yisimo esingamahlalakhona esithinta amaphaphu ethu. Sibangela ukuvuvukala kwemigudu yethu yomoya, amapayipi athwala umoya emaphashini ethu. Imisipha ewazungezile nayo iyaqina. Lokhu kuvuvukala nokuqina kwenza imigudu yomoya ibe bucayi kakhulu. Ngezinye izikhathi, ingavinjelwa yi-mucus.

Abantu abane-asthma babhekana nezimpawu ezifana nokukhwehlela, ukuphefumula kanzima, ubunzima bokuphefumula, kanye nokuqina kwesifuba. Lokhu sikubiza ngokuthi "ukuhlaselwa yi-asthma." Kunezizathu ezahlukahlukene, noma "izimbangela," ezingabangela ukuhlaselwa.

Imbangela enkulu ye-asthma kwabanye abantu yi -allergies . Amasosha omzimba alaba bantu asabela ngokweqile ezintweni ezithile. Sibiza lezi zinto ngokuthi yi-allergens . Kulaba bantu, lapho lezi zinto zingena emzimbeni, ukuhlaselwa yi-asthma kungenzeka.

Umgomo oyinhloko wokwelapha i-asthma ukunciphisa lokhu kuvuvukala nokuqina kwamaphaphu. Lokhu kwenza kube lula ukuphefumula futhi kunciphisa inani lokuhlaselwa yi-asthma.

Umuthi i-Xolair uqukethe isithako esisebenzayo i-omalizumab . Usebenza ngokuvimba into ebizwa ngokuthi i-Immunoglobulin E (IgE) emzimbeni wethu. Lapho i-allergen engikhulume ngayo ekuqaleni ingena emzimbeni, umzimba wethu ukhiqiza inani elikhulu lale IgE. Uma le IgE ivinjiwe emzimbeni womuntu one-asthma ye-allergy, impendulo yomzimba ku-allergens kanye nokuvuvukala kwamaphaphu kuyancishiswa.

Ingabe ukhona umuntu one-asthma ongawusebenzisa lo muthi?

Cha. Iningi labantu abane-asthma lingakwazi ukulawula izimpawu zabo nge-inhaler ejwayelekile. Ngezinye izikhathi, lesi simo silawulwa kahle ngemithi yomlomo.

I-Xolair inikezwa kuphela abantu abane -asthma enzima abangakwazi ukulawula izimpawu zabo naphezu kokusebenzisa umthamo onconywayo kakhulu we-inhaler yabo. Futhi, ukuze usebenzise lo muthi, kumele ukuthi uhlolwe ngokwezokwelapha futhi kwaqinisekiswa ukuthi une-allergy ku-aeroallergen engapheli, njenge-dander yezilwane noma izibungu zothuli.

Uthole kanjani ukuthi lo muthi usebenza kahle kangakanani?

Kwenziwe izifundo eziningi zezokwelapha ukuze kutholakale ukuthi i-Xolair iphephile futhi isebenza kahle yini. Lokhu kwenziwe kokubili kubantu abadala kanye nezingane.

Bonke abahlanganyeli kulolu cwaningo babe nobunzima bokuphefumula ngisho nangemva kokusebenzisa umthamo omkhulu we-inhaler. Kwaqinisekiswa nokuthi banesifo sokungezwani komzimba, njengezibungu zothuli.

Kalula nje, nansi indlela ucwaningo olwenziwe ngayo:

• Iqembu elilodwa lanikezwa umuthi wokugomela i-Xolair. Elinye iqembu lanikwa umuthi wokugomela ongelona iqiniso, i -placebo . Kodwa akekho owayazi ukuthi bathola ini.
• Wonke umuntu watshelwa ukuthi aqhubeke nokusebenzisa ama-inhaler akhe avamile.
• Ngemva kwezinyanga ezimbalwa, umthamo we -corticosteroid inhaler wawo wonke umuntu wehliswa kancane kancane.
• Base bebheka ukuthi labo abathatha i-Xolair babe nokuthula okukhulu yini kunalabo abathatha i-placebo.

Yiziphi izinzuzo zocwaningo?

Izinzuzo ezimbili eziyinhloko zazibonakala ngokucacile.

1. Ukwehla kokuhlaselwa yisifuba somoya okunamandla: Iqembu le-Xolair lalinohlaselo oluphansi kakhulu lwesifuba somoya olunzima kuneqembu le-placebo. Lokhu kwagcinwa ngisho nangemva kokuba umthamo we-inhaler wehlisiwe.

2. Amandla okunciphisa umthamo we-inhaler: Cishe abantu abangu-75% abathathe i-Xolair bakwazile ukunciphisa umthamo wabo wansuku zonke we-corticosteroid inhaler ngesigamu, uma kuqhathaniswa no-50% kuphela walabo abathathe i-placebo.

Usetshenziswa kanjani umuthi wokugomela i-Xolair?

I-Xolair iwumjovo ongaphansi kwesikhumba . Inikezwa njalo emavikini ama-2 kuya kwangama-4. Udokotela wakho uzonquma ukuthi udinga ukuwuthola kangaki umjovo, ngokusekelwe eminyakeni yakho, isisindo, kanye nezinga le-IgE egazini lakho. Umjovo unganikezwa ethangeni, esiswini, noma ngemuva kwengalo engenhla.

Into ebalulekile ukuthi imithamo embalwa yokuqala yomjovo ihlale inikezwa esibhedlela noma emtholampilo. Lokhu kwenzelwa ukuqapha ukuthi unayo yini imiphumela yokungezwani komzimba. Ngemuva kwalokho, uma uhlangabezana nezindinganiso ezithile, udokotela wakho angakuvumela ukuthi uzijove ekhaya.

Kunezindlela ezimbili zokuthola lo muthi. Enye iyithuluzi elifana nepeni elibizwa ngokuthi i-autoinjector . Lokhu kukuvumela ukuthi ujove kalula umuthi wokugoma ngaphandle kokusebenzisa isirinji noma inaliti. Enye iyisirinji ehambisana nenaliti njengenjwayelo. Uma une-allergy ku-latex, ungakhohlwa ukutshela udokotela wakho ngayo. Ngoba amanye amasirinji angase abe ne-latex.

Kuthatha isikhathi esingakanani ukuthola impumuzo kulokhu?

Uma umuthi wokugomela i-Xolair ukulungele, kufanele uqale ukuzizwa ungcono phakathi namasonto ambalwa . Ngokuhamba kwesikhathi, uzoba nokuhlaselwa yi-asthma okumbalwa. Ungase ukwazi nokunciphisa umthamo we-corticosteroid inhaler yakho.

Uma ungezwa lutho olushintshayo ngemva kwezinyanga ezimbalwa, yazisa udokotela wakho ngalokho.

Imiphumela emibi nokuthi ungayiphatha kanjani?

Abantu abasebenzisa i-Xolair bangase babe namathuba amancane okuthola izifo zokuphefumula (umphimbo obuhlungu, umkhuhlane). Indlela engcono kakhulu yokuvimbela lokhu ukugeza izandla zakho njalo, uhlale uhlanzekile, futhi uhlale kude nabantu abagulayo. Futhi uthole umjovo wakho womkhuhlane waminyaka yonke.

Akuvamile kakhulu, abanye abantu bangaba nokusabela okukhulu kokungezwani komzimba, okubizwa ngokuthi i-anaphylaxis , ngemva komthamo wokuqala. Lesi yisimo esibi kakhulu. Yingakho imithamo yakho yokuqala embalwa inikezwa njalo esibhedlela. Lapho, abasebenzi bezokwelapha abaqeqeshiwe bazokuqapha futhi balungele ukukwelapha ngokushesha uma kuvela izinkinga.

Akuzona lezi kuphela, kodwa neminye imiphumela emibi ingase ivele. Uma unezimpawu ezikukhathazayo, khuluma nodokotela wakho.

Ingabe kungaba nezinkinga ngeminye imithi?

Akukho ukuxhumana okungathi sína okwaziwayo phakathi kwe-Xolair neminye imithi. Kodwa-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi (ebhalwe ngudokotela noma ethengwa ngaphandle kwemithi kadokotela), amavithamini, imithi yamakhambi, kanye nezithasiselo ozithathayo.