Ake sithi uye kobona udokotela ukuze ayohlolwa njalo futhi wathola imiphumela yokuhlolwa kwegazi lakho. Udokotela, owabheka umbiko, uthe, "Ama-enzyme akho esibindi aphakeme kancane." Uyabona ukuthi amanani aphambi kwezinhlamvu ezimbili u-ALT no-AST embikweni wakho aphakeme kunokuvamile. Kujwayelekile ukuzizwa wesaba kancane uma lokhu kwenzeka. Kodwa ungesabi. Namuhla sikhuluma ngesimo esibizwa ngokuthi "i-Transaminitis", lapho ama-enzyme esibindi ephakama khona.
Kalula nje, iyini i-Transaminitis?
I-'Transaminitis' akuyona inkinga yezokwelapha engathi sína. Kusho ukuthi amazinga ama-enzyme athile abizwa ngokuthi 'ama-transaminase' egazini lakho akhuphuke kakhulu. Ama-enzyme amabili ayinhloko yi -'Alanine Transaminase (ALT)' kanye ne-'Aspartate Transaminase (AST)' .
Cabanga ngesibindi sakho njengefektri enkulu. Lawa ma-enzyme ayizisebenzi ezingaphakathi kwamaseli aleyo fektri. Ngokuvamile, lawa basebenzi bangaphakathi efektri. Kodwa uma isibindi singaphansi kohlobo oluthile lokucindezeleka, umonakalo, noma ukucindezeleka, amangqamuzana esibindi ayalimala futhi amanye ala basebenzi ayavuza, okungukuthi, egazini lethu. Ngombiko wokuhlolwa kwegazi, silinganisa inani lama-enzyme aqongeleleke egazini.
Esikhathini esiningi, lesi simo sitholakala ngengozi. Amazinga aphezulu e-ALT kanye ne-AST atholakala ngesikhathi sokuhlolwa kwegazi okwenziwe ngesinye isizathu. Kodwa-ke, kwabanye abantu, lapho benezimpawu ezifana ne-jaundice, ukuphuzi kwamehlo nesikhumba, noma ubuhlungu ohlangothini oluphezulu lwesokudla lwesisu, udokotela uyala lezi zivivinyo, ikakhulukazi ukuhlola ukusebenza kwesibindi.
Ingabe kuyingozi ukuthi la ma-enzyme akhushulwe?
Le nkinga yinto abantu abaningi abanayo. I-'Transaminitis' iyisixwayiso sokuqala sokuthi kukhona umonakalo othile kumaseli esibindi. Kufana nesibani 'senjini yokuhlola' emotweni ezayo. Sikutshela ukuthi kukhona okungahambi kahle ngemoto, futhi udinga ukukubheka. Futhi kunjalo nalokhu.
Ubukhulu balokhu buxhomeke embangela eyinhloko .
- Izimbangela zesikhashana: La ma-enzyme angakhuphuka okwesikhashana uma uthatha imithi ethile noma ngenxa yokutheleleka kwesikhashana. Uma imbangela isihambile, isibindi siyalulama futhi amazinga e-enzyme abuyela esimweni esijwayelekile.
- Izimbangela zesikhathi eside: Kodwa-ke, uma lo monakalo uqhubeka ngenxa yesifo esingamahlalakhona, ungaba mubi kakhulu ngokuhamba kwesikhathi. Isibindi sethu sinekhono elimangalisayo lokuphulukisa, kodwa uma umonakalo uqhubeka, silahlekelwa yilelo khono futhi singaholela esimweni esibizwa ngokuthi ukwehluleka kwesibindi.
Ngakho-ke, lokhu akuyona inombolo eyodwa kuphela. Kuyinkomba ebalulekile ekunikeza umbono wempilo yakho iyonke.
Yiziphi izimbangela ezingaba khona ze-transaminitis?
Kungaba nezizathu eziningi zalokhu. Ake sizihlukanise ngezigaba ezimbili: izizathu ezivame kakhulu kanye nezizathu ezingavamile kakhulu.
| Imbangela | Incazelo elula |
|---|---|
| Izimbangela Ezivamile | |
| Isifo Sesibindi Esinamafutha | Njengamanje, kuyimbangela evame kakhulu eSri Lanka. Ngokukhethekile, isimo esibizwa ngokuthi isifo sesibindi esihlobene ne-Metabolic dysfunction-associated steatotic (MASLD) . Izici ze-metabolic ezifana nokudla okungekuhle, ukukhuluphala, isifo sikashukela, kanye ne-cholesterol ephezulu zibangela lokhu. |
| Ukusetshenziswa kotshwala ngokweqile (i-Hepatitis ebangelwa utshwala) | Ukuphuza utshwala ngokweqile kulimaza isibindi ngqo, okungaholela ekulimaleni kwesibindi kwesikhashana noma kwesikhathi eside. |
| Ukutheleleka Ngegciwane (I-Hepatitis Ebangelwa Yigciwane) | Amagciwane anjenge-hepatitis A, B, C, D, kanye no-E angabangela ukuvuvukala kwesibindi. Lokhu kungaholela ku -hepatitis B kanye no-C okungapheli. |
| Imiphumela ebangelwa yimithi (i-Toxic Hepatitis) | Eminye imithi yokunciphisa ubuhlungu, imithi yokwehlisa i-cholesterol, imithi yofuba, neminye imithi ingathinta isibindi. Udokotela uhlala eqaphile ngalokhu. |
| Izimbangela Ezingavamile Kakhulu | |
| Ezinye izizathu | Izimo ezifana nezinkinga zesimiso somzimba sokuzivikela (i-autoimmune hepatitis), izifo ezizuzwe njengefa (i-hemochromatosis, isifo sikaWilson), ukuhlaselwa yinhliziyo, i-jaundice, isifo se-thyroid, kanye nomdlavuza wesibindi ongavamile. |
Ingabe kusho okuthile okukhethekile uma i-AST iphakeme kune-ALT?
Ngokuvamile, uma isibindi sonakele, womabili la ma-enzyme ayanda ndawonye. I-enzyme i-ALT iqondene kakhulu nesibindi. Lokho kusho ukuthi itholakala kakhulu esibindini. Kodwa-ke, i-enzyme i-AST itholakala nasemisipheni yenhliziyo, emisipheni yamathambo, nakwezinye izicubu ngaphezu kwesibindi.
Ngakho-ke, uma inani le-AST liphakeme kakhulu kunenani le-ALT , udokotela uzocabangela nezinye izici. Isibonelo:
- Isifo sesibindi esibangelwa utshwala: Kulesi simo, isilinganiso se-AST/ALT siyanda.
- I-Cirrhosis: Le ndlela ingabonakala ngisho nalapho isifo siqhubeka.
- Izimbangela Ezingaphandle Kwesibindi: Amazinga e-AST angakhuphuka nasezimweni ezifana ne-myocardial ischemia noma ukulimala okukhulu kwemisipha (i-rhabdomyolysis).
Okubaluleke kakhulu: Lawa amacebiso nje. Ungazami ukuzixilonga ngokusekelwe embikweni wakho. Lokho kufanele kwenziwe ngudokotela wakho nakanjani.
Udokotela ukwelapha kanjani lokhu?
Okokuqala, khumbula ukuthi ayikho ikhambi eliqondile le-'Transaminitis'. Ngoba akusona isifo, kodwa uphawu. Ngakho-ke, umgomo oyinhloko kadokotela ukuthola imbangela yama-enzyme aphezulu nokwelapha leyo nkinga.
Inqubo yokwelapha ivame ukuhamba kanje:
1. Umlando wezokwelapha: Udokotela uzokubuza ngendlela ophila ngayo (ukudla, ukuzivocavoca, ukusebenzisa utshwala), imithi oyiphuzayo, kanye nanoma yiziphi izimo zezokwelapha emndenini wakho.
2. Ukuhlolwa okwengeziwe: Kuzoyalwa ukuhlolwa okwengeziwe ukuqinisekisa imbangela.
- Phinda ukuhlolwa kwegazi.
- Ukuhlolwa kwamagciwane e-hepatitis B kanye ne-C.
- Ukuskena kwe-ultrasound yesisu.
- Uma kudingeka, ukuhlolwa kwegazi okukhethekile.
3. Ukwelashwa ngokwembangela: Ukwelashwa kunqunywa ngemva kokutholwa kwembangela.
- Isibindi Esinamafutha: Izinguquko endleleni yokuphila zibalulekile. Ukudla okunempilo , ukuvivinya umzimba njalo , kanye nokwehlisa isisindo kubalulekile.
- Uma kungenxa yotshwala: Isixazululo kuphela ukuyeka ukusebenzisa utshwala ngokuphelele .
- Uma kungenxa yomuthi: Udokotela uzonquma ukuthi uzowushintsha yini umuthi noma anciphise umthamo.
- Uma kungenxa yegciwane: Ukwelashwa kwalelo gciwane kuzoqala.
Ezimweni eziningi, uma imbangela eyinhloko iphathwa kahle, umonakalo wesibindi uyaphela futhi amazinga e-enzyme abuyela esimweni esijwayelekile.
Umlayezo Wokuya Nawe Ekhaya
- I-Transaminitis (ama-enzyme esibindi aphakanyisiwe) iyisibonakaliso esiyisixwayiso sokuthi isibindi sakho singaphansi kokucindezeleka okuthile. Ungesabi uma uyibona.
- Kungaba nezizathu eziningi zalokhu. Isibindi esinamafutha, ukusetshenziswa kotshwala, izifo ezibangelwa amagciwane, kanye nemithi ethile kuyizimbangela ezivamile.
- Ukwelashwa akuqondiswe ezingeni le-enzyme, kodwa esimweni esiyisisekelo esibangele ukuthi ikhuphuke.
- Uma ubona amazinga aphezulu e-ALT kanye ne-AST ekuhlolweni kwegazi lakho, ungalokothi ukushaye indiva. Qiniseka ukuthi ubona udokotela wakho ukuze uthole iseluleko nokwelashwa okufanele.
- Ezimweni eziningi, ukwamukela indlela yokuphila enempilo (ukudla okuhle, ukuvivinya umzimba) kuwusizo olukhulu ekugcineni impilo yesibindi.
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
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💬 Uma umuntu equleka, yiziphi 'izimo ezibulalayo/eziphuthumayo' ezidinga ukulaliswa esibhedlela ngokushesha, kunokuba nje athulule amanzi ebusweni ahlale ekhaya?
Uma uwa bese uvuka ngemizuzwana embalwa/uma uwa ngemva kokulala phansi, zama ukunikeza amanzi/ushukela. Kodwa ingozi enkulu! Ngaphambi kokuba ulahlekelwe ingqondo bese uwe, uma 1) unesihlungu esifubeni/ukuhlaselwa yinhliziyo noma ubunzima bokuphefumula, 2) unesifo sokuwa/ukuquleka lapho uwe, 3) uwa futhi ungasho lutho/usekwi-coma imizuzu eminingana, kufanele ushayele i-ambulensi ngokushesha bese ubayisa esibhedlela!
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