Isifo se-Sickle Cell yisimo esingaba yinselele yangempela empilweni. Yilabo kuphela abaye babhekana naso abazi ukuthi kunzima kangakanani ukuphila nobuhlungu obungapheli, ukukhathala, nezinye izinkinga. Kodwa-ke, ngokuthuthuka kwesayensi yezokwelapha, kutholakale imithi emisha yokulawula izifo ezinjalo. Enye indlela yokwelapha entsha nephumelelayo yi-Voxeletor. Ngakho-ke uma udokotela wakho ekunike lo muthi, kubaluleke kakhulu ukuba nolwazi oluphelele ngawo. Namuhla, ake sixoxe ngala maphilisi e-Voxeletor.
Uhlobo luni lomuthi i-Voxeletor?
Kalula nje, i-Voxeletor uhlobo olukhethekile lomuthi olusetshenziswa ukwelapha isifo se-sickle cell . Ngokwezokwelapha, ingeyesigaba semithi ebizwa ngokuthi 'i-hemoglobin S polymerization inhibitors'.
Manje ungase uzibuze ukuthi kuyini lokho. Kulula kakhulu. Umuntu onesifo se-sickle cell uneprotheni ebizwa ngokuthi i-hemoglobin emaselini akhe abomvu egazi ehluke kancane. Uma amazinga omoya-mpilo ephansi, lawa ma-molecule e-hemoglobin ayanamathelana, akhe amaketanga amade ashintsha ukuma kwamangqamuzana abomvu egazi. Amaseli abomvu egazi ajwayelekile agoba abe yisimo se-sickle. Lawa maseli esickle yiwo abhajwa emithanjeni yegazi emincane, okubangela izinkinga ezifana nobuhlungu kanye nomonakalo wezitho zomzimba.
Ngakho-ke, lokho okwenziwa yi-Voxeletor ukuthi ivimbela ama-molecule e-hemoglobin ukuthi angahlangani ndawonye (i-polymerization). Lokhu kunciphisa amangqamuzana abomvu egazi amise okwesikela futhi kuwasize agcine isimo sawo esifanele. Lokhu kuvumela igazi ukuthi ligeleze kangcono futhi kunciphisa izinkinga zesifo ngezinga elikhulu.
Izinto okufanele uzitshele udokotela wakho ngaphambi kokuqala lo muthi
Ngaphambi kokuqala ukwelashwa nge-Voxeletor, kubalulekile ukunikeza udokotela wakho incazelo ephelele yesimo sakho sempilo. Qiniseka ukuthi ukhuluma ngalezi zinto ngokukhethekile.
- Uma unesifo sesibindi: Uma ukusebenza kwesibindi sakho kukubi, kungathinta indlela umuthi osuswa ngayo emzimbeni wakho. Ngakho-ke, udokotela wakho kungadingeka ashintshe umthamo.
- Uma uke waba nokusabela kokungezwani komzimba ne-Voxeletor noma yimuphi omunye umuthi noma ukudla: Abanye abantu bane-allergy emithini ethile. Ngakho-ke qiniseka ukuthi usitshela uma uke waba nokuhlangenwe nakho kwangaphambilini.
- Uma ukhulelwe noma uhlela ukukhulelwa: Kudingeka uqaphele kakhulu ngokusebenzisa imithi ngesikhathi sokukhulelwa. Ngakho-ke qiniseka ukuthi ukhuluma nodokotela wakho ngalokhu.
- Uma ungumama oncelisayo: Eminye imithi ingadluliselwa enganeni yakho ngobisi lwebele. Ngakho-ke, yazisa udokotela wakho ngalokhu futhi.
Ngingawasebenzisa kanjani la maphilisi?
Ukuze uthole okuningi ngomuthi, kubaluleke kakhulu ukuwusebenzisa ngendlela efanele.
- Gwinya leli philisi lonke ngengilazi yamanzi. Ungalokothi uliphule, ulichoboze, noma ulihlafune. Gwinya iphilisi lonke. Ukwehluleka ukwenza kanjalo kungashintsha indlela umuthi omuncwa ngayo emzimbeni, kunciphise ukusebenza kwawo.
- Ungawuthatha lo muthi udle noma ungadli. Kodwa-ke, uma uzwa ubuhlungu besisu noma isicanucanu, kungcono ukuwuthatha ngemva kokudla.
- Thatha umuthi wakho nsuku zonke, njengoba uyalelwe udokotela wakho. Ungawuthathi ngolunye usuku bese uwuyeka ngolunye usuku.
- Ngisho noma uzizwa ungcono, ungayeki ukuthatha imithi ngaphandle kweseluleko sikadokotela wakho.
Okubalulekile: Lo muthi unikezwe wena kuphela. Unganiki lo muthi kunoma ubani onezimpawu ezifanayo nezakho. Kungaba yingozi.
Uma unikeza izingane lo muthi...
Odokotela banikeza lo muthi ezinganeni ezingaphezu kweminyaka eyi-12 kwezinye izimo ezikhethekile. Kodwa-ke, udokotela wezingane kufanele enze isinqumo. Ngakho-ke, uma unikeza ingane yakho lo muthi, khuluma nodokotela wakho ngokucophelela bese uthola iseluleko.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma ukhohlwa ukuthatha umthamo, ungakhathazeki. Yeqa umthamo ongawusebenzisi bese uthatha umthamo olandelayo ngesikhathi esijwayelekile. Ungalokothi uthathe umthamo ophindwe kabili ukuze ubuyisele umthamo okhohliwe.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma ucabanga ukuthi uthathe okungaphezu komthamo onqunyiwe, shayela iNational Poisons Information Centre eColombo National Hospital ngokushesha. Ngaphandle kwalokho, iya e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze ngokushesha.
Eminye imithi engasebenzisana ne-Voxeletor
Eminye imithi oyithathayo ingathinta indlela esebenza ngayo i-Voxeletor. I-Voxeletor ingashintsha nendlela esebenza ngayo eminye imithi. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini, amakhambi emithi, kanye nezithasiselo) .
| Uhlobo lomuthi | Inothi |
|---|---|
| Ama-antifungal (isb. i-fluconazole, i-ketoconazole) | Lokhu kungakhuphula izinga le-Voxeletor emzimbeni. |
| Imithi yokwelapha isifo sofuba (isib. `rifampin`) | Lokhu kunganciphisa ukusebenza kahle kwe-Voxeletor. |
| Ukwelashwa nge-HIV (isb. i-efavirenz) | Imiphumela ye-Voxeletor ingathonywa. |
| Ezinye izidakamizwa zokudambisa (isib. i-midazolam) | I-Voxeletor ingashintsha imiphumela yale mithi. |
Lolu hlu aluphelele. Ngakho-ke tshela udokotela wakho ngayo yonke imithi oyiphuzayo, uma ubhema, nokuthi uphuza utshwala.
Imiphumela emibi engase ivele ngenxa yalo muthi
Njenganoma yimuphi umuthi, i-Voxeletor ingabangela imiphumela emibi kwabanye abantu. Eminye yale miphumela ingaba yingozi, ngakho-ke kubalulekile ukuyiqaphela.
| Imiphumela emibi kakhulu okufanele ibikwe kudokotela ngokushesha | |
|---|---|
| Ukusabela Kokungezwani Nomzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kwezindebe, ulimi noma ubuso, ubunzima bokuphefumula. |
| Izimpawu Zegazi Eliqhekekile | Ubuhlungu besifuba obungazelelwe, ubunzima bokuphefumula, ubuhlungu obungazelelwe, ukuvuvukala, noma ukubomvu emlenzeni. |
| Imiphumela emibi evame ukungabi yingozi, kodwa okufanele ibikwe kudokotela uma iqhubeka | |
| Izinkinga zesistimu yokugaya ukudla | Ubuhlungu besisu, isifo sohudo, isicanucanu. |
| Ezinye izinkinga ezincane | Ikhanda elibuhlungu, ukukhathala, umkhuhlane. |
Uma uhlangabezana nanoma yiziphi ezinye izimpawu ezingavamile ezingashiwongo kulolu hlu, khuluma nodokotela wakho ngazo futhi.
Ngingawugcina kanjani umuthi?
- Yigcine kude nezingane ezincane .
- Gcina ekamelweni lokushisa, ngaphansi kwama-degree Celsius angu-30 (ama-degree Fahrenheit angu-86). Vikela ekushiseni okukhulu kanye nomswakama.
- Lahla imithi ephelelwe yisikhathi ngaphandle kokuyisebenzisa.
Umlayezo Wokuya Nawe Ekhaya
- I-Voxeletor umuthi obalulekile ovimbela amangqamuzana abomvu egazi ekushintsheni isimo sesifo se-sickle cell futhi unciphise izinkinga zesifo.
- Ngaphambi kokuqala lo muthi, tshela udokotela wakho ngalo lonke ulwazi lwakho lwezempilo kanye nayo yonke eminye imithi oyithathayo.
- Gwinya iphilisi lonke, ngaphandle kokuliphula, ukulichoboza, noma ukulihlafuna. Thatha umthamo owunikeziwe ngesikhathi osinqunyiwe.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi efana nokuvuvukala kobuso, ubunzima bokuphefumula, noma ubuhlungu besifuba, funa iseluleko sezokwelapha ngokushesha.
- Lo muthi ungowakho wedwa. Ungalokothi uwuhlanganyele nabanye. Uma unezinkinga, khuluma nodokotela wakho njalo.
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