Dɛn ne DHT? Ɛka wo nipadua dɛn? (Dihydrotestosterone a ɛwɔ nipadua no mu) .

So woate DHT anaa Dihydrotestosterone ho asɛm pɛn ? Ebia yiw, ebia ɛnte saa. Nanso eyi yɛ biribi a ɛho hia paa ma yɛn nipadua, titiriw ma mmarima akwahosan. Enti, ɛnnɛ yɛbɛka DHT yi ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw so a wubetumi ate ase.

Dɛn ne DHT (dihydrotestosterone)? Sɛ yɛbɛka no tiawa a...

Sɛ yɛbɛka no tiawa a, DHT yɛ hormone titiriw bi a ɛboa ma mmarima nya nna mu su . Wunim, hormone ahorow te sɛ abɔfo nketewa a wɔhwɛ yɛn nipadua no dwumadi biara so. DHT nso ka hormone kuw bi a wɔfrɛ no Androgen ho. Androgen ne din a wɔde frɛ nkwaadɔm a ɛma mmarima su.

Susuw ho hwɛ, DHT fi ase yɛ adwuma wɔ ɔbarima nipadua mu fi bere a ɔwɔ awotwaa mu no. Afei, dwuma a DHT di no sesa wɔ mmere ahorow mu wɔ n’asetra mu. Ɛwom sɛ nyansahufo nnim sɛnea DHT ka mmea ankasa de, nanso wosusuw sɛ ebia ɛbɛka nhwi a enyin wɔ nipadua no so ne kokoam mmeae.

Androgen titiriw a ɛwɔ ɔbarima a wanyin mu ne testosterone . Saa testosterone yi bɛyɛ 10% dan DHT da biara . Saa adeyɛ yi kɔ so wɔ honam ani a atwa ɔbarima ne ɔbea nna ho ahyia ne prostate ntini mu wɔ mmarima mu. Wɔ mmea mu no, eyi si wɔ honam ani. Ɛsan ba mmeae te sɛ yɛn mmerɛbo. Esiane sɛ mmarima fi awosu mu wɔ testosterone pii wɔ wɔn nipadua mu nti, wɔn DHT dodow nso kɔ soro kɛse.

Dɛn na DHT yɛ yɛn nipadua ankasa?

DHT yɛ nneɛma ahorow wɔ ɔbarima asetra mu mmere ahorow mu. Ɛho hia titiriw bere a awotwaa no nyin ne ne babunbere mu .

Nanso, nea ɛnte sɛ testosterone no, DHT nni dwuma titiriw biara wɔ nipadua no dwumadi a ɛkɔ so tra hɔ wɔ ɔbarima a wanyin mu no mu. Wɔ mpanyin afe so no, wohu DHT titiriw wɔ tebea horow te sɛ prostate a ɛtrɛw ne mmarima ti nhwi a ɛyera mu.

Dwuma a DHT di wɔ awotwaa mu

Bere a akokoaa wɔ awotwaa mu no, ne nna mu akwaa nyin sɛ ɔbarima anaa ɔbea a egyina hormone tebea pɔtee bi so. Wɔ abarimaa fam no, DHT ne nkwaadɔm afoforo (a testosterone ka ho) yɛ adwuma de siw mmea nna mu su ahorow ano na ɛma mmarima nna mu su ahorow nyin .

DHT ho hia ma ɔbarima akyi awotwaa, ɔbarima akyi berɛmo ne akyi berɛmo, a ɛwɔ akokoaa mu no nyin. DHT nso boa ma prostate gland no nyin.

DHT wɔ mmerantebere ne mmabaabere mu

Bere a abarimaa du ne babunbere mu no, DHT boa ma ɔbarima no akyi berɛmo ne ne mmadwoa nyin kɔ akyiri. Ɛnyɛ ɛno nko, na mmom DHT nso titiriw na ɛyɛ:

• Wɔ animAbɔgyesɛ a wonyin.
• Nipadua mu nhwi a ɛrenyin.
• Nwi a enyin wɔ mmeae a ankorankoro wɔ.
• Prostate a enyin.

Sɛ DHT dodow kɔ soro a, dɛn na ɛba?

Akwahosan tebea horow bi ne DHT dodow a ɛkɔ soro wɔ abusuabɔ. Momma yɛnhwɛ nea wɔyɛ:

• Prostatic Hyperplasia a Ɛnyɛ Den (BPH) .
• Prostate kokoram
• Androgenetic alopecia (mmarima ti nhwi a ɛtɔ ) .
• Polycystic Ovarian Syndrome (wɔ mmea mu) `(Nneɛma a ɛyɛ den a ɛma obi ho yɛ hyew - PCOS)`

Prostatic Hyperplasia a Ɛnyɛ Den (BPH) ne DHT

Benign Prostatic Hyperplasia (BPH) yɛ wo prostate ntini a ɛtrɛw. Ɛyɛ tebea a abu so kɛse wɔ mmarima a wɔadi boro mfe 50 mu .

Wo prostate gland no betumi ama DHT pii aba. Saa DHT yi kanyan prostate gland no dwumadi a ɛfata, na ɛtaa ma prostate gland no trɛw. Saa BPH yi betumi de ɔhaw ahorow te sɛ ɛyɛ den sɛ wobɛtow ne nna mu ɔhaw ahorow aba .

Prostate kokoram ne DHT

Mpɛn pii no, nnipa a wɔwɔ prostate kokoram no wɔ DHT pii. Prostate kokoram betumi afi DHT dwumadi a ɛkɔ soro wɔ wo prostate mu, a awosu mu nsakrae ahorow bi a ɛma prostate nkwammoaa nyin a wontumi nni so ka ho.

Androgenetic alopecia (nwi a ɛtɔ) ne DHT

Androgenic alopecia ne nea yɛtaa frɛ no male pattern baldness . Wɔ tebea yi mu no, nhwi fi ti no atifi ne anim. Bere kɔ so no, nhwi no twetwe.

Ade biako a ɛde saa ti nhwi a ɛtɔ yi ba ne DHT dwumadi a ɛkɔ soro wɔ wo ti nhwi mu. Nneɛma afoforo nso wɔ hɔ a ɛde ba, te sɛ awosu mu nkɛntɛnso. Sɛ DHT dodow kɔ soro a, nhwi no mu ntini no so tew, nhwi no nyin kyinhyia no yɛ tiaa, na awiei koraa no, nhwi no gu.

PCOS ne DHT

Polycystic Ovarian Syndrome (PCOS) yɛ hormone a ɛnkari pɛ a ɛka mmea. Ɛba bere a wɔn mmadwoa no ma androgen hormone pii dodo, a testosterone ka ho. Eyi ma DHT dodow kɔ soro. Eyi betumi de sɛnkyerɛnne ahorow aba, a nea ɛka ho ne bra a ɛnkɔ so daa, nipadua mu nhwi a enyin dodo (hirsutism), ne akisikuru .

Sɛ DHT dodow so tew a, dɛn na ɛba?

Tebea horow bi ne DHT dodow a ɛba fam wɔ abusuabɔ. Momma yɛnhwɛ nea wɔyɛ:

• 5-alpha reductase a enni hɔ `(5-alpha reductase a enni hɔ)`
• Testosterone a ɛba fam / ɔbarima hypogonadism

DHT dodow a ɛba fam sen sɛnea ɛte daa no ka mmarima titiriw. Nyansahufo binom gye di sɛ DHT dodow a ɛba fam wɔ mmeawa mu no betumi akyɛ mmabunbere.

5-alpha reductase a enni nipadua mu ne DHT

5-alpha reductase yɛ enzyme a ɛboa ma wɔdan testosterone ma ɛbɛyɛ DHT. Awosu mu nsakrae a ɛka enzyme yi a wɔyɛ no betumi ama DHT dodow akɔ fam anaasɛ enni hɔ. Wɔfrɛ eyi 5-alpha reductase a enni hɔ. Eyi yɛ tebea a wonya fi awofo hɔ kɔ mmofra hɔ (autosomal recessive pattern) .

5-alpha reductase a enni hɔ no ka awotwaa a wɔyɛ mmarima (wɔn a wɔwɔ XY chromosomes) no nna mu nkɔso. Nkokoaa mmarima a wɔwo wɔn a wɔwɔ saa sintɔ yi taa da su ahorow a edidi so yi adi:

• Akyi akwaa a ɛwɔ akyi no nnyinii koraa.
• Nkwammoaa a ɛyɛ adwuma a ɛwɔ nipadua no mu (a ennya mfii mu).
• Prostate gland ketewaa anaasɛ enni hɔ.

Nea ɛho hia: Wɔ nsɛm a emu yɛ den a 5-alpha reductase nni mu no, nkokoaa a wɔyɛ mmarima a wɔwɔ awosu mu nkwaadɔm a wɔwɔ XY chromosomes no betumi anya mmea akyi awotwaa. Nanso, DHT a ɛso atew no nnya mmadwoa (ɛda so ara tumi ma mmadwoa) ne ɔbarima ne ɔbea nna mu akwaa no nyin. Eyi yɛ soronko wɔ tebea bi a wɔfrɛ no Androgen Insensitivity Syndrome ho. Nnipa a wɔwɔ saa tebea yi wɔ mmadwoa a ɛfata na testosterone dodow a ɛfata anaasɛ ɛkɔ soro, nanso wonni androgen agyefo, enti wonnya nna mu su a ɛto so abien, na wɔn nso ntumi nwo pii.

Mmarimaa a wɔwɔ awosu mu yare a wɔfrɛ no 5-alpha reductase deficiency no nnya anim nhwi bere a wɔadu wɔn mpanyin afe so no. Nanso, wɔn nipadua da so ara yɛ testosterone, na ɛde nneɛma te sɛ nne a emu dɔ, ntini nyin, ne ɔbarima akyi berɛmo a ɛtrɛw ba.

Testosterone dodow a ɛba fam ne DHT

Testosterone a ɛwɔ wo nipadua mu no na ɛdan DHT. Enti, sɛ wo testosterone dodow sua a, wo DHT dodow nso bɛba fam asen sɛnea ɛte daa. Edin foforo a wɔde frɛ testosterone dodow a ɛba fam ne mmarima hypogonadism.

Mmarima hypogonadism ahorow atitiriw abien na ɛwɔ hɔ: classical (ɛwɔ hɔ wɔ awo mu anaa akyiri yi wɔ nkwa mu) ne nea efi ase akyiri yi. Ɛdenam mfe a woadi so no, mmarima hypogonadism betumi de ɔhaw ahorow aba.

So ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn fa me DHT dodow ho asɛm?

Sɛ wususuw sɛ ebia wo anaa wo ba no wɔ tebea bi a DHT a ɛba fam anaasɛ ɛkɔ soro na ɛde ba a, hwɛ hu sɛ wo ne oduruyɛfo bɛkasa.Afei obetumi ayɛ nhwehwɛmu a ɛho hia anaasɛ ɔde wo bɛkɔ obi a ne ho akokwaw wɔ endocrine nhyehyɛe mu, te sɛ endocrinologist.

Dihydrotestosterone, anaa DHT, ho hia ma mmarima nna mu nkɔso. Nanso sɛ ne dodow kɔ soro dodo anaasɛ ɛba fam dodo a, ebetumi de ɔhaw ahorow te sɛ akyi akwaa a ennyaa nkɔso, prostate a ɛtrɛw, ne ti nhwi a ɛtɔ. Sɛ wowɔ nneɛma bi a ɛhaw wo wɔ wo DHT dodow ho a, ntwentwɛn wo nan ase sɛ wo ne wo duruyɛfo bɛkasa. Wobetumi ayɛ nhwehwɛmu na wɔakamfo ayaresa ahorow a ebetumi aboa wo akyerɛ.

Nneɛma a ɛho hia sen biara a ɛsɛ sɛ wokae fi asɛm yi mu (Take-Home Message) .

• DHT yɛ androgen hormone a ɛboa titiriw ma mmarima nya nna mu su .
• DHT ho hia ma mmarima akyi awotwaa a ɛnyin wɔ awotwaa mu ne anim nhwi ne nipadua mu nhwi nyin wɔ mmerantebere ne mmabaabere mu.
• DHT dodow a ɛkɔ soro no betumi de tebea horow te sɛ benign prostatic hyperplasia (BPH), prostate kokoram, ti nhwi a ɛtɔ wɔ mmarima mu, ne PCOS wɔ mmea mu aba.
• Sɛ DHT dodow sua a, tebea horow te sɛ 5-alpha reductase a enni nipadua no mu betumi aka mmarima nna mu nkɔso.
• Sɛ w’adwene mu yɛ wo naa anaasɛ ɛhaw wo wɔ wo DHT dodow ho a, ɛbɛyɛ papa sɛ wobɛhwehwɛ aduruyɛfo afotu .

Mewɔ anidaso sɛ seesei woanya DHT ho ntease pa. Nneɛma a ɛte sɛɛ a wubehu no ho hia paa ma w’akwahosan!

` DHT, dihydrotestosterone, hormone, mmarima akwahosan, testosterone, prostate, ti nhwi a ɛtɔ, PCOS