So wote nka sɛ woabrɛ wɔ ɔkwan soronko so, wo mu duru a ɛkɔ soro anaa ɛso tew mpofirim a wontumi nkyerɛkyerɛ mu, anaasɛ worehu nsakrae wɔ wo honam ani? Sɛ wo duruyɛfo ahyɛ nyansa sɛ wɔnyɛ "ACTH nhwehwɛmu" a, ɛyɛ awosu sɛ wobɛte nka sɛ wohaw wo kakra anaasɛ w'adwene tu fra. Yɛsrɛ sɛ mma ɛnhaw wo. Eyi yɛ mogya mu nhwehwɛmu a wɔahyɛ da ayɛ a wɔde hwɛ sɛnea wo nipadua mu nkwaadɔm no yɛ adwuma. Wɔ Nirogi Lanka no, yɛpɛ sɛ yɛkyekyɛ eyi mu yɛ no nsɛmfua a ɛnyɛ den sɛnea ɛbɛyɛ a wobɛte nea ɛrekɔ so no ase yiye.
Dɛn ankasa ne ACTH?
Wo nipadua yɛ nhyehyɛe a ɛyɛ nwonwa a afã horow nam nnuru abɔfo a wɔfrɛ no "hormones" so di nkitaho. Fa no sɛ pituitary gland a ne kɛse te sɛ pea a ɛwɔ w'amemene no ase no yɛ ahyehyɛde kɛse bi "General Manager".
Saa ɔpanyin yi de akwankyerɛ pɔtee bi a wɔfrɛ no ACTH (Adrenocorticotropic hormone) mena . Saa sɛnkyerɛnne yi kɔ wo adrenal glands , a ɛtra w’asaabo atifi te sɛ kyɛw nketewa no mu tẽẽ. Fa saa ntini ahorow yi sɛ adwumayɛbea. Sɛ pituitary gland no de ACTH sɛnkyerɛnne no kɔ ara pɛ a, adrenal adwumayɛbea no yɛ hormone bi a ɛho hia a wɔfrɛ no cortisol .
Dɛn nti na Cortisol ho hia wo saa?
Cortisol nyɛ hormone a ɛyɛ mmerɛw ara kwa; ɛyɛ dwumadi ahorow pii a ɛho hia wɔ wo nipadua mu:
- Ɛboa ma wo mogya mmoroso ( mogya mmoroso ) yɛ adwuma yiye .
- Ɛma wo nipadua nya ahoɔden a ɛbɛko atia nyarewa yiye.
- Ɛboa ma asikre , srade , ne protein ahorow a efi aduan a wudi mu no mu paapae ma ɛma ahoɔden ba.
- Ɛboa wo nipadua ma etumi di honam ne nkate fam nhyɛso ho dwuma.
Wubetumi ahu nea enti a nhyehyɛe yi ho hia saa. Sɛ ACTH sɛnkyerɛnne a efi pituitary gland no mu no kɔ soro a, adrenal glands no ma cortisol pii. Sɛ ACTH so tew a, cortisol a wɔyɛ no brɛ ase. Mpɛn pii no, wo duruyɛfo hyɛ sɛ wɔnyɛ ACTH nhwehwɛmu mfa nhwɛ sɛ saa kari pɛ yi adum —titiriw sɛnea ɛbɛyɛ a obehu sɛ wo dodow no dɔɔso dodo anaasɛ ɛba fam dodo.
Nea ɛho hia sen biara no, wɔtaa yɛ ACTH sɔhwɛ no ka cortisol ( Cortisol ) sɔhwɛ ho, efisɛ saa nkwaadɔm abien yi dwumadi wɔ abusuabɔ kɛse.
Dɛn nti na ebia wo duruyɛfo bɛhyɛ sɛ wɔnyɛ nhwehwɛmu yi?
ACTH a ɛnkari pɛ ho sɛnkyerɛnne ahorow ne sɛ ebia wo cortisol dodow dɔɔso dodo anaasɛ ɛba fam dodo no wɔ abusuabɔ tẽẽ.
| Mu duru a Ɛkɔ Anim | Titiriw srade a ɛboaboa ano wɔ anim, akyi atifi, ne mmati ho. |
| Nsakrae a Ɛba Honam ani | Ntrɛwmu a ɛyɛ pink anaa kɔkɔɔ a ɛba yafunu, asen, anaa nufu so. |
| Mrɛyɛ | Ntini mu mmerɛwyɛ ne ɔbrɛ a ɛkɔ so tra hɔ, a ɛtra so. |
| Nsɛnkyerɛnne Afoforo | Ɛnyɛ den sɛ wɔbɛpirapira, akisikuru, nipadua mu nhwi a enyin dodo wɔ mmea mu, ne mogya mmoroso. |
| Mu duru a Wɔtew So | Mu duru a ɛso tew a wontumi nkyerɛkyerɛ mu ɛmfa ho sɛ aduan ho akɔnnɔ a ɛfata no. |
| Nsɛm a Ɛfa Digestive Ho | Akisikuru a ɛtaa ba, ɔfe, yafunu mu yaw, anaa akisikuru. |
| Nsakrae a Ɛba Honam ani | Wora a ɛyɛ tuntum (hyperpigmentation), titiriw wɔ mmeae te sɛ nsateaa ne nkotodwe. |
| Nsɛnkyerɛnne Afoforo | Ɔbrɛ a emu yɛ den, adwenemhaw, ne nnuan a nkyene wom ho akɔnnɔ a emu yɛ den. |
Ɛdenam sɛnkyerɛnne ahorow yi a wo duruyɛfo bɛhwehwɛ mu so no, obetumi ahwehwɛ tebea horow te sɛ Cushing yare (cortisol a ɛdɔɔso), Addison yare (cortisol a ɛba fam), anaa nsɛm a ebetumi aba wɔ pituitary ho mu. ACTH sɔhwɛ no yɛ adwinnade titiriw a wɔde hu yare a ɛma nneɛma a ebetumi aba yi mu da hɔ.
Sɛnea wobesiesie wɔn ho ama sɔhwɛ no
Esiane sɛ eyi yɛ mogya mu nhwehwɛmu nti, enhia sɛ wosiesie no kakraa bi. Nanso esiane sɛ nneɛma pii betumi anya nea ebefi mu aba no so nkɛntɛnso nti, wo duruyɛfo akwankyerɛ a wubedi akyi ho hia .
- Steroid Nnuru: Sɛ wode nnuru biara a wɔde steroid ayɛ di dwuma a, ebia wo duruyɛfo bɛka akyerɛ wo sɛ gyae bɛyɛ nnɔnhwerew 48 ansa na wɔayɛ nhwehwɛmu no, efisɛ ebetumi asakra nea efi mu ba no kɛse.
- Aduane: Ebia wɔbɛka akyerɛ wo sɛ mmuada (biribiara nni hɔ a wubedi anaa wobɛnom) fi anadwo fã ansa na wɔayɛ sɔhwɛ no. Ebia wobetu wo fo nso sɛ hwɛ sɛnea wudi carbohydrates ( carbohydrates ) ( aduan mu nsakrae ).
- Apɔw-mu-teɛteɛ ne Adwennwen: Kwati apɔw-mu-teɛteɛ a emu yɛ den anaa adwennwen a ɛho nhia wɔ nnɔnhwerew 12 a edi sɔhwɛ no anim no mu, efisɛ eyinom betumi aka hormone dodow.
- Ahomegye Pa: Fa si w’ani so sɛ wobɛda yiye ansa na woayɛ sɔhwɛ no, efisɛ nna a wonnya betumi aka wo hormone ahorow.
- Da Nnuru nyinaa adi: Hwɛ hu sɛ wobɛbɔ wo duruyɛfo amanneɛ wɔ nnuru (aduru a wɔkyerɛw ma wo, nhabannuru, nnuru a wɔde ka aduan ho, anaa vitamin) a worenom mprempren nyinaa ho.
Ɔkwan a Wɔfa so Yɛ ne Ahobammɔ
Adeyɛ no yɛ nea wɔyɛ no daa na ɛnyɛ den; ɔyarehwɛfo bi begye mogya afi ntini bi a ɛwɔ wo basa mu mu.
Yɛsrɛ sɛ hyɛ no nsow sɛ ACTH ne cortisol dodow sakra da mũ no nyinaa. Mpɛn pii no, ACTH dodow no kɔ soro bɛyɛ anɔpa 8:00 na ɛkɔ nea ɛba fam sen biara anadwo. Sɛnea ɛbɛyɛ na woanya mfonini a edi mũ no, ebia wo duruyɛfo no bɛhwehwɛ sɛ wogye mogya anɔpa na ebia foforo nso anwummere.
Sɛ wɔboaboa ano wie a, wɔma nhwɛsode ahorow no dwo ntɛmntɛm wɔ nsukyenee so, efisɛ ACTH yɛ hormone a ebetumi asɛe ntɛmntɛm.
Ɛdefa asiane ahorow ho no, nhwehwɛmu yi kura asiane ahorow a wɔahyɛ da ayɛ te sɛ mogya a wɔtwe foforo biara: ɛyaw ketewaa bi anaasɛ akuru wɔ baabi a wɔde ade no ahyɛ no, na ɛntaa nsi koraa, ɔyare mmoawa ketewaa bi. Biribiara nni hɔ a ɛbɛma wɔabɔ kɔkɔ kɛse.
Nea Efi Mu Ba no Nkyerɛase
Ebia ɛsono kakra wɔ mmeae a wɔde gyina hɔ ma wɔ aduruyɛdan ahorow ntam. Mpɛn pii no, wɔ ɔpanyin a ɔwɔ apɔwmuden fam no, ɛsɛ sɛ ACTH dodow a ɛwɔ 8:00 AM no so tew fi picogram 10-50 wɔ mililita biara mu (pg/mL).
Nanso, yɛsrɛ sɛ mmɔ mmɔden sɛ wubegyina w’amanneɛbɔ so ahu wo ho . Nneɛma pii nya dodow yi so nkɛntɛnso:
- So wodaa yiye anadwo a edii ɛno anim no?
- So na worehyia adwennwen kɛse?
- Nnuru afoforo bɛn na worenom (sɛ nhwɛso no, insulin, hormone pills)?
- Sɛ ɛfata a, wo brayɛ no fã bɛn na wowɔ?
- So wuhyiaa opira anaa ahodwiriw bi nnansa yi?
- So wodii nhwɛsode no ho dwuma na wɔde siee nsukyenee so yiye?
Wo duruyɛfo bɛbom ahwɛ wo ACTH ne cortisol aba no nyinaa mu. Wɔrennyina nɔma biako so nhu yare no. ACTH a ɛkɔ soro a cortisol dɔɔso wom no ka asɛm foforo sen ACTH a ɛkɔ soro a cortisol sua.
Sɛ wo nsa ka wo nea efi mu ba no wie a, yɛsrɛ wo yɛ nhyehyɛe kɔ wo duruyɛfo nkyɛn. Wɔasiesie wɔn yiye sɛ wɔbɛkyerɛ nea wɔahu yi ase wɔ w’akwahosan nyinaa mu na wɔatu fo wɔ anammɔn biara a edi hɔ a ɛho hia ho, a ebia nea ɛka ho ne nhwehwɛmu foforo a wɔbɛyɛ de ahu.
Nkrasɛm a Wɔde Kɔ Fie
- ACTH nhwehwɛmu yɛ mogya mu nhwehwɛmu a ɛkyerɛ hormone a wo pituitary gland no gyae na ɛboa ma wohu sɛnea adrenal gland no yɛ adwuma.
- Wɔtaa yɛ nhwehwɛmu yi de ka cortisol hormone nhwehwɛmu ho.
- Ebia wo duruyɛfo bɛkamfo nhwehwɛmu yi akyerɛ sɛ wowɔ sɛnkyerɛnne ahorow te sɛ wo mu duru a wɔsakra a wontumi nkyerɛkyerɛ mu, ɔbrɛ a enni sabea, anaa wo honam ani nsakrae a.
- Wo duruyɛfo akwankyerɛ (a ɛfa aduan, nnuru, ne apɔw-mu-teɛteɛ ho) a wubedi akyi pɛpɛɛpɛ ansa na woayɛ nhwehwɛmu no ho hia na ama woanya nea efi mu ba no pɛpɛɛpɛ.
- Mmɔ mmɔden sɛ w’ankasa wobɛkyerɛ wo sɔhwɛ mu aba no ase. Bere nyinaa kɔ wo duruyɛfo nkyɛn na woanya nkyerɛkyerɛmu a ɛfa adwumayɛfo ho ne akwankyerɛ a ɛfa wo ho.
