Momma yensua Aldosterone a ɛka wo mogya mmoroso wɔ kokoam no ho ade.

Ɔhaw a nnipa pii wɔ wɔ Sri Lanka ne mogya mmoroso. Wɔ ebinom fam no, ɛyɛ den yiye sɛ wobedi eyi so bere a wɔanom nnuru mpo awie no. Nanso obi wɔ yɛn nipadua mu a yɛnka ne ho asɛm pii, nanso onya mogya mmoroso so nkɛntɛnso wɔ kokoam. Ɛno na yɛrebɛka ho asɛm nnɛ. Ne din de Aldosterone.

Sɛ yɛbɛka no tiawa a, hena ne saa aldosterone yi?

Aldosterone yɛ hormone bi a ɛwɔ yɛn nipadua mu. Hormone ahorow te sɛ postmen a wɔwɔ yɛn nipadua mu no. Wɔde nkrasɛm kɔ akwaa biara so, ka kyerɛ no sɛ ɔnyɛ eyi, gyae saa.

Enti ntini nketewa abien a ɛyɛ ahinanan a ɛte sɛ kyɛw a ɛwɔ yɛn asaabo atifi na ɛyɛ saa hormone a wɔfrɛ no aldosterone yi. Yɛfrɛ eyinom adrenal glands. Saa ntini ahorow yi yɛ yɛn endocrine nhyehyɛe no fã.

Adwuma titiriw a saa hormone yi yɛ ne sɛ ɛbɛma yɛn mogya mmoroso akɔ so ayɛ nea ɛfata . Ɛyɛ eyi denam minerals dodow a ɛwɔ yɛn mogya mu a wɔfrɛ no sodium (ɛno ne nkyene) ne potassium a ɛhwɛ so no so. Saa sodium ne potassium yi yɛ electrolytes ahorow abien . Wɔn na ɛma nipadua no mu nsu kari pɛ na ɛboa ma ntini ne ntini ahorow yɛ adwuma yiye.

Ɔkwan bɛn so na aldosterone di mogya mmoroso so?

Eyi yɛ adeyɛ a ɛyɛ anigye yiye. Aldosterone ka mogya mmoroso titiriw wɔ akwan a edidi so yi so:

1. Sodium a Ɛkora So: Aldosterone ma yɛn asaabo ne yɛn akyi berɛmo no kyerɛ sɛ "ɛmfa sodium (nkyene) pii nka mogya no mu na ɛma potassium dodow a ɛba nsu mu no nkɔ soro."

2. Nsuo a ɛtumi sie: Sɛ wɔde sodium ka mogya no ho a, nsuo nso kɔ nipadua no mu. Ɛte sɛ nea nsu twetwe nkyene.

3. Mogya dodow a ɛkɔ soro: Sɛ yɛkora nsu so wɔ yɛn nipadua mu a, yɛn mogya dodow nyinaa kɔ soro. Sɛnea sɛ wode nsu pii hyɛ nsu afiri mu ma ne nhyɛso yɛ kɛse no, saa ara na sɛ mogya dodow kɔ soro a, mogya mmoroso nso kɔ soro.

Wɔ saa kwan yi so no, sɛ yɛn mogya mmoroso so tew a, aldosterone de ne ho hyɛ mu na ɛboa ma ɛsan kɔ baabi a ɛfata. Saa hormone yi nso boa ma wɔhwɛ mogya no mu pH (i.e., acid-base kari pɛ) ne electrolyte dodow so wɔ ɔkwan a ɛnteɛ so.

Ɔkwan bɛn so na wodi aldosterone dodow yi so? - a ɛyɛ nwonwa a ɛkɔ so!

Aldosterone nkutoo ntumi nyɛ adwuma. Ɛyɛ kuw bi a wɔbom yɛ adwuma no fã. Yɛfrɛ nhyehyɛe yi Renin-Angiotensin-Aldosterone System (RAAS) . Ɛte sɛ relay mmirikatu.

Susuw ho saa kwan yi so.

• Ade a edi kan: Wo mogya mmoroso (BP) so tew. Yɛn asaabo te eyi nka. Afei asaabo no yi enzyme bi a wɔfrɛ no renin kɔ mogya no mu.
• Anamɔn a ɛto so abien: Saa renin yi kɔ na ɛpaapae protein bi a wɔfrɛ no angiotensinogen a yɛn mmerɛbo na ɛyɛ no mu ma ɛyɛ asinasin bi a wɔfrɛ no angiotensin I. Nanso ɛda so ara da hɔ, a ɛkyerɛ sɛ enni tumi pii.
• Anamɔn a Ɛto so Abiɛsa: Afei, bere a saa angiotensin I yi fa mogya no mu no, angiotensin-converting enzyme (ACE) a efi yɛn ahurututu mu no bubu, na ɛma wonya hormone bi a tumi wom yiye a wɔfrɛ no angiotensin II . Oyi ne ɔbran ankasa.
• Anamɔn a Ɛto so Anan: Saa angiotensin II yi yɛ nneɛma atitiriw abien.

1. Ɛma mogya ntini nketenkete (arterioles) no twetwe. Eyi ma mogya mmoroso kɔ soro ntɛm ara.

2. Ɛkɔ adrenal glands no mu na ɛka kyerɛ wɔn sɛ, "Emergency! Ntɛm ara yɛ aldosterone!"

• Anamɔn a etwa to: Afei aldosterone ba mu na ɛka kyerɛ asaabo no sɛ ɔnkora nkyene (sodium) ne nsu so na nyi potassium bi mfi mu. Eyi ma mogya dodow kɔ soro na ɛma mogya mmoroso san kɔ sɛnea ɛsɛ.

Sɛ wɔyɛ saa adeyɛ yi nyinaa wie, na mogya mmoroso san ba sɛnea na ɛte kan no a, nhyehyɛe yi to mu ara kwa. Eyi yɛ nhyehyɛe a ɛyɛ den yiye, nanso ɛyɛ nwonwa yiye a wɔde di dwuma.

Ɔkwan bɛn so na wosusuw aldosterone dodow?

Sɛ wo duruyɛfo no rehyia ɔhaw wɔ wo mogya mmoroso so, anaasɛ nsakrae ba wo mogya mu potassium dodow mu a, ebia obesusuw sɛ aldosterone wɔ hɔ. Sɔhwɛ titiriw a wɔde yɛ eyi ne aldosterone:renin ratio sɔhwɛ .

Esiane sɛ aldosterone ne renin bom yɛ adwuma nti, sɛ wosusuw abien no nyinaa dodow a, ebetumi aboa ma wɔahu baabi pɔtee a ɔhaw no wɔ. Wɔtaa yɛ eyi denam mogya kakraa bi a wogye fi ntini bi a ɛwɔ wo nsa mu no so.

Nea ɛka ho no, wobetumi asusuw aldosterone dodow wɔ mogya anaa nsu a wɔaboaboa ano wɔ nnɔnhwerew 24 mu no mu wɔ ɔkwan soronko so.

Sɛ aldosterone dodow kɔ soro a, dɛn na ɛba?

Sɛ aldosterone dodow a ɛwɔ nipadua no mu dɔɔso sen sɛnea ɛte daa a, yɛfrɛ no hyperaldosteronism . Nea ɛde eyi ba titiriw ne tebea bi a wɔfrɛ no aldosteronism titiriw . WeiWɔsan frɛ no Conn’s syndrome.

Mpɛn pii no, akisikuru ketewaa bi a ɛnyɛ kokoram (a ɛnyɛ papa) a ɛba wɔ adrenal gland mu na ɛde tebea yi ba. Saa akisikuru yi ma ntini no ma aldosterone dɔɔso dodo. Eyi ma sodium (nkyene) kɔ soro wɔ mogya no mu, potassium so tew, na electrolyte a ɛnkari pɛ.

Sɛ aldosterone dodow so tew a, dɛn na ɛba?

Afei nso, sɛ aldosterone dodow a ɛwɔ nipadua no mu no sua sen sɛnea ɛte daa a, yɛfrɛ no hypoaldosteronism . Eyi ne bere a aldosterone hormone no nyɛ kɛse anaasɛ ne dwumadi sɛe no. Eyi betumi ama sodium (nkyene) a ɛwɔ mogya mu no so atew, potassium akɔ soro, ne tebea bi a wɔfrɛ no metabolic acidosis ( acid a ɛkɔ soro wɔ mogya no mu).

Dɛn ne nea enti a ɛte saa?

• Addison yare no:Eyi yɛ yare a ɛntaa nsi a nipadua no tumi ko tia nyarewa. Eyi kyerɛ sɛ nipadua no ankasa ahobammɔ nhyehyɛe no dan ne ho na ɛsɛe adrenal ntini ahorow no. Eyi ma nkwaadɔm a wɔfrɛ no aldosterone ne cortisol nyinaa a wɔyɛ no so tew.
• Congenital Adrenal Hyperplasia (CAH): Eyi yɛ awosu mu tebea a ɛwɔ hɔ bere a wɔawo no. Ɛma enzyme ahorow bi a ehia na wɔde ayɛ hormone ahorow a ɛwɔ adrenal glands no mu no so tew.
• Ayaresa mu tebea afoforo: Saa tebea yi betumi aba nnipa a wɔwɔ asikreyare, asaabo mu yare, ne wɔn a wɔyare denneennen no so.
• Nnuru bi: Nnuru a wɔde kum ɛyaw (NSAID) , nnuru a ɛma mogya tew te sɛ heparin, ne koma mu nnuru bi nso betumi de saa tebea yi aba.

Sɛ wowɔ saa sɛnkyerɛnne ahorow yi a, ɛho hia yiye sɛ wobɛyɛ nhyehyɛe akɔ wo duruyɛfo nkyɛn na woaka eyi ho asɛm.