Blastocyst wɔ tiawa mu: Anamɔn a edi kan wɔ nyinsɛn a ahoɔden wom mu (Blastocyst) .

Sɛ woyɛ obi a wowɔ anidaso sɛ wobɛwo mma, titiriw sɛ woreyɛ awo a wontumi nwo ho ayaresa a, ɛbɛyɛ sɛ woate asɛmfua ‘Blastocyst’ afi wo duruyɛfo hɔ. Wɔtaa te saa asɛmfua yi, titiriw bere a wɔreka ayaresa te sɛ IVF ho asɛm no. Sɛ wote eyi a, ebia ɛbɛyɛ te sɛ nea nyansahu mu de kakra na ɛyɛ den ma wo. Nanso mma nsuro. Sɛ yɛbɛka no tiawa a, eyi ne w’anidaso mfiase ketewaa bi, nanso ɛho hia yiye. Ɛnnɛ, yɛbɛka nea Blastocyst yi yɛ, nea ɛyɛ, ne sɛnea ɛho hia ma nyinsɛn ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw na adamfofa su so.

Sɛ yɛbɛka no tiawa a, dɛn ne Blastocyst?

Fa no sɛ, bere a ɔbarima a ɔwɔ apɔwmuden mmadwoa ma ɔbea a ɔwɔ apɔwmuden nkesua no nyin akyi no, wɔfrɛ nkwammoaa a edi kan a ɛba no zygote. Saa nkwammoaa no fi ase paapae ntɛmntɛm. Baako bɛyɛ abien, abien bɛyɛ anan, ne nea ɛkeka ho, na ɛyɛ ade ketewaa bi a ɛte sɛ bɔɔl a wɔfrɛ no blastocyst .

Sɛ yɛbɛka no tiawa a, blastocyst yɛ awotwaa no mfiase pɛɛ . Ɛba bɛyɛ nnanu kosi asia bere a mmadwoa bi ma ɛwo bi akyi. Eyi yɛ ade titiriw a ɛho hia yiye wɔ nyinsɛn no mu. Eyi ne bere a saa nkwammoaa yi bom na ɛbata awotwaa no fasu ho no. Yɛfrɛ eyi a wɔde hyɛ nipadua mu.

Saa Blastocyst fã yi ho hia titiriw wɔ IVF (In Vitro Fertilization) mu efisɛ nnuruyɛfo betumi apaw Blastocyst a ɛwɔ apɔwmuden na anya nkɔso sen biara na wɔde ahyɛ ɛna no awotwaa mu. Eyi ma nyinsɛn a edi mu a ebetumi aba no yɛ kɛse.

Ɔkwan bɛn so na ɔkwan a wɔfa so nyinsɛn abofra no ba?

Sɛ yɛbɛte hia a blastocyst no ho hia ase yiye a, ɛboa sɛ wubenya adwene kakra wɔ ɔkwan a wɔfa so nyinsɛn abofra no nyinaa ho. Momma yɛnhwɛ sɛnea akwantu nwonwaso yi kɔ so anammɔn biara.

1. Ovulation: Mpɛn pii no, bɛyɛ nnafua 14 akyi bere a ɔbea bi awo ɔsram biara fi ase no, ɛmo (ovum) a ɛho akokwaw fi ne mmadwoa biako mu. Saa nkesua yi fa awotwaa no mu na ɛtwɛn sɛ mmadwoa bi bɛwo no.

2. Nkokoaa: Sɛ ɔbarima ne ɔbea nna kɔ so wɔ saa bere yi mu a, mmadwoa bi betumi ahyia nkesua a ɛwɔ awotwaa mu no na ɛne no ayɛ biako. Eyi ne nea yɛfrɛ no fertilization.

3. Zygote no a wɔhyehyɛ: Yɛfrɛ ɛmo a wɔahyɛ no ma no ‘zygote’. Eyi ne nkwammoaa biako a edi kan a ɛka ɛna ne agya nyinaa awosu bom.

4. Akwantu a ɛkɔ Blastocyst Stage:Saa zygote yi sian fallopian tube no mu kɔ awotwaa no mu bɛyɛ nnansa kosi anum. Ɛntra hɔ ara, ɛkɔ so kyekyɛ. Nkwammoaa abien, anan, awotwe... ɛpaapae ntɛmntɛm na ɛbɛyɛ bɔɔl ketewaa bi a nkwammoaa ɔhaha pii ne abura bi wɔ mu. Ɛno ne nea yɛfrɛ no Blastocyst .

5. Wɔde hyɛ awotwaa mu: Sɛ blastocyst no du awotwaa no mu wie a, ɛtra hɔ nna kakraa bi na ɛbata awotwaa no mu ɔfasu (endometrium) ho. Eyi ne nea yɛfrɛ no ‘implantation’.

6. Awotwaa ne Awotwaa: Bere a wɔde ahyɛ awotwaa mu akyi no, saa nkwammoaa yi kɔ so mu paapae na enyin ma ɛbɛyɛ awotwaa. Bɛyɛ adapɛn 9 akyi no, saa awotwaa yi nyin kɔ akyiri na ɛbɛyɛ akokoaa, a ɛyɛ akokoaa a ɛyɛ ne nyinaa sɛnea yenim no no.

Dɛn ne blastocyst dwumadi? Dɛn nti na eyi ho hia saa?

Blastocyst fã no yɛ ade a ɛho hia yiye na wontumi nkwati wɔ awotwaa ne awotwaa mu nkɔso mu. Nea enti a ɛyɛ mmerɛw ne sɛ , sɛ blastocyst no anhyɛ awotwaa no fasu mu yiye a, nyinsɛn rensi.

Saa nipadua a wɔde hyɛ nipadua no mu yi nam anwonwakwan so na ɛba. Wɔ hormone ahorow a ɛwɔ yɛn nipadua mu nkɛntɛnso ase no, blastocyst no fa adeyɛ bi a wɔfrɛ no "hatching." Sɛnea akokɔ ba fi nkesua mu tow no, saa ara na blastocyst no bubu ne akyi ntini a ɛyɛ tratraa (zona pellucida) no mu. Eyi si wɔ da koro anaa abiɛsa akyi bere a ɛhyɛn awotwaa no mu no.

Afei adwuma ankasa no si. Nkwammoaa abien na ɛwɔ blastocyst no mu.

• Trophoblast: Saa nkwammoaa yi na edi kan bata awotwaa no fasu ho. Wɔyɛ eyi denam protein a ɛyɛ nnam (L-selectin) a ɛte sɛ gluu a wɔyɛ so. Akyiri yi saa nkwammoaa yi na ɛyɛ awotwaa no . Awotwaa no yɛ akwaa a ɛho hia yiye a ɛma akokoaa no nya mframa pa ne aduannuru na eyi nneɛma fĩ fi akokoaa no mu.
• Nkwammoaa a ɛwɔ mu: Nkwammoaa dodow yi bɛkɔ anim akyiri yi abɛyɛ akokoaa .

Nkwammoaa bi a ɛwɔ awotwaa no mu bom yɛ amniotic sac, nsu kotoku a ɛbɔ akokoaa no ho ban no.

Dɛn ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ wɔde blastocyst no ahyɛ nipadua mu?

Nnipa dodow no ara nhu sɛnkyerɛnne biara wɔ saa bere yi mu. Nanso nnipa binom, bɛyɛ nkyem abiɛsa mu biako, betumi anya yare no ho sɛnkyerɛnne bi. Ebia eyinom ne sɛnkyerɛnne a edi kan a ɛkyerɛ sɛ woanyinsɛn. Nanso ɛnyɛ obiara na onya saa sɛnkyerɛnne ahorow yi, na sɛ wunya saa sɛnkyerɛnne ahorow yi a, ɛnkyerɛ sɛ woanyinsɛn. Enti ɛyɛ papa bere nyinaa sɛ wo ne wo duruyɛfo bɛkasa.

So Blastocyst betumi ama nyinsɛn agu?

Eyi yɛ asɛmti a ɛyɛ nkate a ɛsɛ sɛ yɛka ho asɛm, nanso ɛho hia sɛ wuhu. Yiw, blastocyst betumi atu nyinsɛn anaasɛ entumi mfa nhyɛ nipadua no mu yiye. Nokwarem no, nyinsɛn a ɛtɔ ntɛm paa no mu bɛyɛ 75% fi blastocyst no a entumi nhyɛ mu yiye.

Dɛn nti na eyi rekɔ so?

Ade titiriw nti a ɛte saa ne nkwaadɔm mu nkwaadɔm a ɛnteɛ.Sɛ nkwammoaa a ɛwɔ blastocyst no mu no mu paapae a, ɛtɔ mmere bi a ɔhaw ahorow betumi aba chromosomes no mu. Sɛ nhwɛso no, ebia chromosome foforo bi wɔ hɔ, chromosome bi ayera, anaasɛ chromosome bi fã bi betumi abubu.

Sɛ nyinsɛn a wɔde hyɛ nipadua no mu no di nkogu wɔ saa kwan yi so a, nyinsɛn betumi afi ase nanso agyae ntɛm paa (bɛyɛ adapɛn 5). Eyi ne nea yɛfrɛ no "nnuru nyinsɛn." Gye sɛ wo nna no aka akyi anaasɛ woayɛ nyinsɛn mu nhwehwɛmu a, ebia wunnim mpo sɛ eyi asi.

Ɛntaa mma koraa sɛ blastocyst a ɛwɔ chromosomal a ɛnyɛ ne kwan so betumi de ahyɛ nipadua mu na nyinsɛn no akɔ so. Wɔ tebea horow a ɛtete saa mu no, asiane wɔ hɔ sɛ akokoaa no benya tebea horow te sɛ Down syndrome, Klinefelter syndrome, anaa Turner syndrome.

So ɔkwan bi wɔ hɔ a wɔfa so di kan hu saa nkwaboaa mu haw ahorow yi bere a wɔde IVF rekɔ so no?

Yiw, esiane sɛ nnɛyi nnuruyɛ anya nkɔso nti, eyi ano aduru wɔ hɔ. Wɔ IVF ayaresa mu no, ansa na wɔde blastocyst no bɛhyɛ awotwaa no mu no, wobetumi ayi nkwammoaa kakraa bi afi mu na wɔasɔ ahwɛ sɛ ebia nkwaboaa mu ɔhaw ahorow wɔ hɔ anaa.

Wɔfrɛ sɔhwɛ yi Preimplantation Genetic Testing (PGT) .

Ɛdenam sɔhwɛ yi so no, nnuruyɛfo betumi apaw blastocyst a ɛwɔ chromosomally apɔwmuden no de ahyɛ awotwaa no mu. Enti,

• Sɛnea ɛbɛyɛ yiye sɛ nyinsɛn no bɛkɔ yiye no kɔ soro.
• Asiane a ɛwɔ hɔ sɛ nyinsɛn a wobetu ntɛm no so tew.
• Ebetumi atew asiane a ɛwɔ hɔ sɛ wobɛwo abofra a ne nipadua mu nkwaadɔm a ɛnyɛ ne kwan so no so.

Wɔ obi a onyinsɛn fi awosu mu fam no, wobetumi ayɛ nhwehwɛmu ahorow yi wɔ nyinsɛn adapɛn 9 anaa 10 akyi nkutoo.

So wobetumi atew asiane a ɛwɔ nkwaboaa a ɛnteɛ mu no so?

Nea ɛyɛ awerɛhow no, asiane ahorow bi yɛ nea yentumi nyɛ ho hwee.

• Sɛ́ wadi boro mfe 35.
• Sɛ́ wubenya abusua abakɔsɛm a ɛkyerɛ sɛ obi anya nkwaboaa mu yare.
• Sɛ́ wadi kan atu nyinsɛn anaasɛ wawo akokoaa a ɔwɔ nkwaboaa mu ɔhaw bi.

Sɛ wowɔ asiane ahorow yi a, ɛho hia yiye sɛ wo ne wo duruyɛfo ne awosu ho ɔfotufo kasa bere a woreyɛ nhyehyɛe sɛ wobɛwo ba no.

Nanso, nneɛma bi wɔ hɔ a yebetumi adi so. Sɛ yedi asetra pa a yedi akyi ansa na yɛanyinsɛn ne bere a yɛanyinsɛn akyi a, yebetumi atew asiane a ɛwɔ hɔ sɛ yebepira akokoaa no so.

• Kwati sɛ wode wo ho bɛhyɛ nneɛma a awuduru wom mu.
• Kwati nnubɔne ne nsa a wɔnom koraa.
• Di aduan a ɛkari pɛ.
• Fa vitamin ahorow a ɛho hia sɛnea wo duruyɛfo aka wo fo no.

Blastocyst no yɛ mfiase titiriw ma nyinsɛn a ahoɔden wom. Sɛ annyin yiye na wɔde ahyɛ awotwaa no mu a, nyinsɛn rensi. Sɛ wunya nsensanee anaa ɛyaw biara wɔ nyinsɛn no mfiase a, mma wo ho nnpopo anaasɛ mmu w’ani ngu so, na mmom kɔ wo duruyɛfo nkyɛn ntɛm ara kɔhwehwɛ afotu. Obetumi ahwehwɛ wo mu na wahwɛ ahu sɛ biribiara rekɔ yiye.