Sɛ wohu sɛ wowɔ kokoram na wofi ase sa wo yare a, ɛyɛ ade a ɛfata sɛ wobɛte nka sɛ woayɛ basaa na w’adwene atu afra. Nanso esiane nnuruyɛ a ɛkɔ akyiri nnɛ nti, nnuru bi wɔ hɔ a ebetumi de wɔn ani asi kokoram nkwammoaa nkutoo so na wɔasɛe wɔn. Ceritinib yɛ aduru pɔtee a ɛte saa, a ɛkɔ anim yiye, a ɛyɛ pɔtee no mu biako. Enti sɛ wɔakyerɛw saa aduru yi ama wo anaa obi a wunim no a, ɛho hia yiye sɛ wubehu nea ɛyɛ ankasa. Momma yɛnka eyi ho asɛm tiawa.
Aduru bɛn na Ceritinib yɛ?
Sɛ yɛbɛka no tiawa a, Ceritinib yɛ "ayaresa a wɔde asi wɔn ani so." Eyi kyerɛ sɛ saa aduru yi de n’ani si protein pɔtee bi a ɛboa ma kokoram nkwammoaa nyin so tẽẽ. Sɛ saa protein ahorow no gyae adwumayɛ a, kokoram nkwammoaa no hwere tumi a wɔde bɛpaapae na wɔanyin no.
Wɔde saa aduru yi sa "ahurututu mu kokoram a ɛnyɛ nkwammoaa nketenkete" titiriw. Sɛ́ anka ɛbɛka nkwammoaa a ɛwɔ nipadua no nyinaa mu te sɛ nnuru a wɔde sa yare daa no, ɛde n’ani si kokoram nkwammoaa so titiriw, na ebetumi atew nea efi mu ba no bi so. Nanso ɛnyɛ ade koro wɔ obiara fam. Zykadia yɛ aduru yi din a wonim no yiye.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru
Ansa na wo duruyɛfo bɛkyerɛw saa aduru yi no, ɛho hia sɛ wunya w’akwahosan ho mfonini a edi mũ. Eyi ho hia paa ma w’ahobammɔ. Enti, sɛ wowɔ tebea horow a wɔabobɔ din wɔ ase ha no bi a, hwɛ hu sɛ wo ne wo duruyɛfo besusuw ho.
- Sɛ wowɔ asikreyare anaa asikre dodow a ɛwɔ wo mogya mu a.
- Sɛ wowɔ komayare ho abakɔsɛm anaasɛ wo koma bɔ a ɛnteɛ a.
- Sɛ woadi kan anya dwensɔtwaa mu yare a.
- Sɛ wowɔ mmerɛbo mu yare a.
- Sɛ magnesium anaa potassium kakraa bi na ɛwɔ wo mogya mu a.
- Sɛ wowɔ ahurututu anaa ɔhome mu yare te sɛ ayamtu a.
- Sɛ worebɔ mmɔden sɛ wubenyinsɛn, woanyinsɛn dedaw, anaasɛ worenom nufu a.
- Sɛ wowɔ akisikuru wɔ Ceritinib aduru yi ho a, lactose, gelatin, anaa aduru foforo biara, aduan, anaa ade a ɛkora so.
Ɔkwan bɛn so na ɛsɛ sɛ mede aduru no di dwuma?
Akwankyerɛ pɔtee a wɔde bedi dwuma wɔ aduru yi a wɔde bedi dwuma ho a wobedi akyi no ho hia yiye na ama ayaresa no ayɛ yiye.
- Fa ka aduan ho: Ɛsɛ sɛ wɔde saa aduru yi ka aduan ne nsu kuruwa ho. Mfa no bere a wo yafunu da mpan.
- Grapefruit biara nni hɔ: Mfa aduru yi nka grapefruit anaa ne nsu ho. Ebia ɛbɛsakra ɔkwan a wɔfa so twetwe aduru no.
- Mmu anaa nbubu tablet no: Mene tablet no nyinaa. Mmubu, ntwitwa, anaa nwe.
- Fa no bere ano: Fa no sɛnea wo duruyɛfo ka kyerɛ wo no pɛpɛɛpɛ, wɔ bere a ɛfata mu, dodow a ɛfata mu. Nnyae aduru no nom anaasɛ nsakra dodow a wɔde ma no a wunni aduruyɛfo afotu.
Nea ɛho hia: Sɛ wowɔ adwenem naayɛ bi sɛ woanom aduru yi dodo a, mma wo ho nnyɛ wo hu na frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea no ntɛm ara . Anaasɛ kɔ ayaresabea a ɛbɛn wo no Emergency Treatment Unit (ETU) .
Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?
Fa no sɛ wo werɛ afi sɛ wobɛnom w’aduru. Nha wo ho. Sɛ ɛboro nnɔnhwerew 12 kosi sɛ wobɛma wo dodow a edi hɔ a, fa dodow a woayera no bere a woakae ara pɛ. Nanso, sɛ ennu nnɔnhwerew 12 kosi sɛ wobɛma wo dodow a edi hɔ no a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da.
Nnuru afoforo a ebetumi ne ceritinib adi nkitaho (Drug Interactions) .
Ceritinib yɛ aduru a ɛwɔ tumi kɛse sɛ ɛne nnuru afoforo di nkitaho. Enti, ɛho hia sɛ woka nnuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo, a vitamin, nhabannuru, ne nnuru a wɔde ka ho ka ho.
| MMFA Ceritinib nka nnuru yi ho. | |
|---|---|
| Alfuzosin a wɔde yɛ aduru | Lovastatin, Simvastatin a wɔde yɛ aduru |
| Nnuru a ekum fungal te sɛ Fluconazole ne Voriconazole | Cisapride, Dronedarone, na ɔkyerɛwee |
| Ergot alkaloids te sɛ ergotamine | Pimozide, Thioridazine a wɔde yɛ nnuru |
| Lurasidone, Lomitapide, na ɛwɔ hɔ | Triazolam, Tolvaptan, ne nea ɛwɔ hɔ |
| Ebia ne nnuru yi nso bedi nkitaho | |
|---|---|
| Nnuru bi a wɔde ko tia HIV/AIDS | Nnuru bi a ekum ɔyare mmoawa, te sɛ clarithromycin |
| Nnuru a wɔde ko tia akisikuru te sɛ Carbamazepine ne Phenytoin | Warfarin (aduru a ɛma mogya yɛ mmerɛw) . |
| St. John’s Wort (nhabannuru a wɔde yɛ aduan) . | Nnuru afoforo a ɛsakra koma no bɔ (nnuru a ɛma QT kyɛ) . |
Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho bere a worenom nnuru no
Bɔ wo ho ban fi nyarewa ho
Saa aduru yi betumi ama wo nipadua no atumi ako atia nyarewa, kyerɛ sɛ, ahoɔden a ɛko tia nyarewa no ayɛ mmerɛw. Enti,
- Sɛ wuhu sɛnkyerɛnne ahorow te sɛ atiridiinini, atiridiinini, anaa menewam yaw a, nnyɛ wo ho aduru na ka kyerɛ wo duruyɛfo.
- Bɔ mmɔden sɛ wobɛkwati mmeae a nnipa ahyɛ hɔ ma ne nnipa a wɔyare. Hohoro wo nsa mpɛn pii.
- Mfa nnuru a wɔde kum ɛyaw te sɛ aspirin ne ibuprofen a wunnyaa wo duruyɛfo afotu. Ebia wobesiw w’atiridii ano na ama ayɛ den sɛ wubehu ɔyare mmoawa bi.
Nyinsɛn ne nufu a wɔde ma ho nimdeɛ titiriw
Eyi ho hia yiye: Kwati sɛ wubenyinsɛn koraa bere a worenom aduru yi no. Ɛnyɛ papa sɛ wubenyinsɛn asram 6 bere a woagyae aduru no akyi. Sɛ ɔbarima bi renom saa aduru yi a, ɛsɛ sɛ ɔkwati sɛ ɔbɛwo abofra bere a ɔrenom aduru no ne asram 3 bere a wagyae no. Sɛ woyɛ ɛna a woma nufu a, ɛsɛ sɛ wokwati sɛ wobɛma nufu bere a worenom aduru no ne adapɛn 2 wɔ dodow a etwa to no akyi.
Hwɛ yiye wɔ owia ho.
Ebia saa aduru yi bɛma wo honam ani ayɛ mmerɛw wɔ owia ho. Enti, sɛ worekɔ owia mu a, hyɛ ntade a wɔakata so yiye na fa aduru a ɛbɔ wo ho ban fi owia ho di dwuma.
Nsunsuanso bɔne a ebetumi aba esiane nnuru nti
Te sɛ aduru biara no, Ceritinib betumi de ɔhaw ahorow aba. Eyinom bi hwehwɛ sɛ wodi ho dwuma ntɛm ara.
| Sɛ wuhu saa sɛnkyerɛnne ahorow yi a, ka kyerɛ wo duruyɛfo ntɛm ara. | |
|---|---|
| Honam ani akisikuru | Wora mu akisikuru, ɛyaw, anim, anofafa, tɛkrɛma a ɛho ahonhon. |
| Ɔhome a ɛyɛ den | Ɔhome a ɛyɛ den, koko a ɛyɛ den, ɔfe. |
| Koma mu haw ahorow | Koko mu yaw, adwenemhaw, te nka sɛ wo koma rebɔ ntɛmntɛm anaasɛ ɛnyɛ daa, wo totɔ piti. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ mmerɛbo asɛe | Nsu a ɛyɛ kɔkɔɔ/biribiri tuntum, aniwa anaa honam ani yɛ kɔkɔɔ, ɛyaw wɔ yafunu no atifi nifa so, ɔbrɛ a ɛtra so. |
| Asikre a ɛwɔ mogya mu a ɛkɔ soro ho sɛnkyerɛnne | Ano a ɛyɛ nwunu, sukɔm anaa ɔkɔm dodo, nsu a wɔtaa tow. |
| Nsɛnkyerɛnne afoforo a anibere wom | Yafunu mu yaw a emu yɛ den, atiridiinini, atiridiinini, mogya a ɛtɔ anaasɛ akuru a ɛyɛ soronko. |
| Sɛ saa nsunsuanso bɔne yi kɔ so anaasɛ ɛhaw adwene a, ka kyerɛ wo duruyɛfo. | |
| Nneɛma bɔne a ɛtaa ba | Atiridiinini, akisikuru, akisikuru, ɔfe, tiyɛ, adwenemhaw, ɔbrɛ a ɛtra so. |
Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhu sɛnkyerɛnne foforo anaa soronko bi a, wo ne wo duruyɛfo nka ho asɛm.
Nkrasɛm a Wɔde Kɔ Fie
- Fa ceritinib ka aduan ho bere nyinaa . Mfa no nka bobe nsuo ho.
- Ka nnuru afoforo, vitamin, ne nhabannuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo.
- Ɛho hia yiye sɛ wobɛkwati sɛ wubenyinsɛn koraa bere a worenom aduru yi ne bere tenten a wo duruyɛfo kamfo kyerɛ no.
- Sɛ wunya ɔhaw ahorow a emu yɛ den te sɛ wo koko mu yaw, ɛyɛ den sɛ wobɛhome, anaa w’ani a ɛyɛ kɔkɔɔ a, ka kyerɛ wo duruyɛfo ntɛm ara.
- Nnyae ayaresa no esiane biribiara nti a wunnya wo duruyɛfo afotu. Ɛho hia sɛ wotoa ayaresa so, sɛ wote nka sɛ wo ho nyɛ wo dɛ mpo a. Wo ne wo duruyɛfo nkasa mfa biribiara a ɛhaw wo ho.
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