So wo duruyɛfo akyerɛw wo chlorpromazine? Anaasɛ ebia w’abusua muni anaa w’adamfo bi de saa aduru yi redi dwuma. Ɛyɛ aduru a ano yɛ den yiye a wɔtaa kyerɛw ma adwenemyare ahorow. Ɛno nti na ɛho hia paa sɛ wubehu nea saa aduru yi yɛ ankasa ne sɛnea wode bedi dwuma dwoodwoo na ɛteɛ no. Enti ɛnnɛ, momma yɛnka saa aduru yi ho asɛm wɔ ɔkwan tiawa bi a wubetumi ate ase so.
Dɛn nti na wɔde saa Chlorpromazine aduru yi rema yɛn?
Sɛ yɛbɛka no tiawa a, eyi yɛ aduru a wɔde di dwuma wɔ adwenemyare mu. Ɛne sɛ, aduru bi a wɔde ma de siw adwenemhaw ano. Sɛ yɛbɛka no pɛpɛɛpɛ a, eyi ka nnuru kuw a wɔfrɛ no ``Antipsychotics`` no ho.
Eyi yɛ adwuma denam neurotransmitter dopamine a ɛkari pɛ wɔ yɛn amemene mu no so. Susuw ho saa kwan yi so, dopamine yɛ nnuru sobɔfo a ɛboa ma wodi nneɛma te sɛ yɛn adwene, nkate, ne nsusuwii so. Wɔ adwenemyare ahorow bi mu no, dopamine dodow yi bɛyɛ nea ɛnkari pɛ. Ɛno ne bere a wɔde saa aduru yi ma sɛ ɛbɛboa ma wɔasan akɔ nea ɛfata.
Tebea atitiriw a wɔkyerɛw saa aduru yi ma ne:
- Adwene mu yare a ɛma obi yɛ ade tra so
- Adwene a ɛma obi yɛ ade tra so
Nanso ɛnyɛ eyi nko nti, nnuruyɛfo de saa aduru yi di dwuma esiane nneɛma afoforo pii nso nti.
- Di akisikuru ne ɔfe so.
- Gyae hiccups a ennyae no.
- Wɔ yare bi a wɔfrɛ no Porphyria fam no.
- Sɛ ɛba sɛ obi anya tetanus a.
- Ɛtɔ mmere bi a wɔde ma ɔyarefo no bo dwo ansa na wɔayɛ no oprehyɛn.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom nnuru
Eyi yɛ ɔfã a ɛho hia paa. Ansa na wubefi ase anom saa aduru yi no, ɛho hia sɛ wobɔ wo duruyɛfo amanneɛ wɔ aduruyɛ mu tebea foforo biara a wowɔ ho. Efisɛ ebia saa aduru yi ne aduruyɛ mu tebea horow bi bedi nkitaho.
| Sɛ wowɔ saa tebea horow yi bi a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo. | |
|---|---|
| Komayare anaa koma a ɛbɔ a ɛnteɛ ho abakɔsɛm | Mogya mmoroso a ɛba fam |
| Mmɛn mu yare | Asaabo mu yare |
| Asikyireyareɛ | Parkinson yare a ɛma obi nya yare |
| Akisikuru a ɛma obi ho kyere no | Amemene mu akisikuru |
| Glaucoma a ɛma obi ho yɛ hyew | Adwene mu yare |
| Ɔhome a ɛyɛ den anaasɛ ayamtu | Mogya mu nkwammoaa dodow a ɛso tew (e.g. mogya mu nkwammoaa fitaa) . |
| Dwonku a ɛsiw | Prostate ho haw ahorow |
| Ɛyɛ den sɛ wobɛmene | Ɛyɛ den sɛ wobɛtow nsu |
| Sɛ woyɛ obi a ɔtaa nom nsa a | Sɛ woanyinsɛn anaasɛ worebɔ mmɔden sɛ wubenyinsɛn a |
| Sɛ woyɛ ɛna a ɔma nufu a | Sɛ wowɔ aduru yi anaa aduru anaa aduan foforo biara ho akisikuru a |
Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?
Wɔde ano nom saa aduru yi sɛ aduru a wɔde yɛ aduru. Fa nsu kuruwa biako fa. Ɛho hia yiye sɛ wobɛnom dodow a ɛfata, wɔ bere a ɛfata mu, sɛnea wo duruyɛfo akyerɛ wo no. Mma dodow no nkɔ soro anaasɛ ɛntew so sɛnea wote nka sɛ wo ho tɔ wo, anaasɛ fa no mpɛn pii nsen nea wɔakyerɛw ama wo.
Ade a ɛho hia paa:Nnyae saa aduru yi nom mpofirim da a wonkɔ wo duruyɛfo nkyɛn. Eyi betumi ama wanya yare a ɛma obi twe ne ho te sɛ akisikuru, ɔfe, ne adwenemhaw. Sɛ ɛho hia sɛ wugyae aduru no nom a, wo duruyɛfo no betu wo fo wɔ ɔkwan a wobɛfa so ayɛ saa ho.
Sɛ wonom nnuru pii a, dɛn na ɛsɛ sɛ woyɛ? (Nnuru a wɔde ma boro so) .
Sɛ wususuw sɛ woanom saa aduru yi dodo a, kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo ntɛm ara. Anaasɛ frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ no na woanya afotu. Mma nntwentwɛn wo nan ase.
Na sɛ mepa nnuru dodow bi nso ɛ?
Sɛ wo werɛ fi sɛ wobɛnom dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ɛkame ayɛ sɛ bere aso sɛ wobɛma wo dodow a edi hɔ no a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da, a dodow a woayera no ka ho.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Ɛho hia paa sɛ wobɛka nnuru a worenom nyinaa (nnuru a wɔde sa nyarewa afoforo, vitamin, aduru a wɔde di dwuma wɔ amanne kwan so) kyerɛ wo duruyɛfo, efisɛ ebia nnuru bi ne Chlorpromazine bedi nkitaho.
| Mfa Chlorpromazine nka aduru yi ho da. | |
|---|---|
| Cisapride na ɔkyerɛwee | Pimozide a wɔde yɛ nnuru |
| Dronedarone a wɔfrɛ no Dronedarone | Saquinavir a wɔde di dwuma |
| Metoclopramide a wɔde di dwuma | Thioridazine a wɔde ma |
| Eyinom nso betumi ne Chlorpromazine adi nkitaho - ka kyerɛ wo duruyɛfo. | |
| Nsaden | Nnuru a wɔde sa akisikuru, ɔfe, ne atiridiinini (Antihistamines) . |
| Nnuru a wɔde sa adwenemhaw, dadwen, anaa nna | Nnuru a wɔde kum ɛyaw (titiriw nea ɛma obi bow nsa) . |
| Aduru a wɔde sa mogya mmoroso | Nnuru te sɛ Levodopa a wɔde sa Parkinson yare |
| Nnuru a ɛma mogya yɛ mmerɛw te sɛ Warfarin | Aduru a wɔde kum nipadua no ntɛm ara |
Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho bere a worenom nnuru no
- Dae ne adwenemhaw: Ebia saa aduru yi bɛma woate nka sɛ woada, wo ho ayɛ wo yaw, anaasɛ w’ani ayɛ kusuu. Enti , nka kar, nnyɛ mfiri, anaa nyɛ biribiara a ɛhwehwɛ sɛ woma w’ani da hɔ kosi sɛ wubehu sɛnea aduru yi ka wo.
- Sɔre a wobɛsɔre mpofirim: Nsɔre mpofirim mfi tenabea anaa da a wobɛda no mu. Sɛ woyɛ saa a, ebetumi ama obi adwenem ayɛ no naa na wahwe ase. Ɛsɛ sɛ wɔn a wɔn mfe akɔ anim hwɛ yiye titiriw wɔ eyi ho.
- Nsã: Kwati nsa a wobɛnom. Nsã betumi ama woate nka kɛse sɛ woda na wo ho kyere wo.
- Nipadua mu hyew: Saa aduru yi betumi aka sɛnea nipadua no tumi hwɛ ɔhyew so. Eyi kyerɛ sɛ tumi a nipadua no tumi gyina awɔw a ano yɛ den ne ɔhyew a ano yɛ den ano no so betumi atew. Enti, bɔ wo ho ban fi ɔhyew a ano yɛ den ne awɔw a ano yɛ den ho. Nom nsu pii.
- Owia ho nkate: Ebia saa aduru yi bɛma wo honam ani ayɛ mmerɛw wɔ owia ho. Enti, bɔ wo ho ban fi owia ho. Sɛ worekɔ owia mu a, hyɛ ntade a ɛkata wo nipadua so na fa aduru a ɛbɔ wo ho ban fi owia ho di dwuma.
- Asikre a ɛwɔ wo mogya mu: Sɛ wowɔ asikreyare a, saa aduru yi betumi ama asikre a ɛwɔ wo mogya mu no akɔ soro. Enti hwɛ asikre dodow a ɛwɔ wo mogya mu daa. Sɛ ɛho hia a, wo ne wo duruyɛfo nkasa mfa nsakrae a wobɛyɛ wɔ w’aduan anaa asikreyare aduru mu ho.
- Ano a ɛyɛ mmerɛw: Ano a ɛyɛ mmerɛw yɛ ade a ɛtaa ba wɔ aduru yi mu. Wobetumi adi eyi ho dwuma denam anom a asikre nnim a wɔbɛwe, ahwiesa a asikre nnim a wɔbɛnom, ne nsu pii a wɔbɛnom so.
Dɛn ne nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ nnuru nyinaa no, eyi betumi anya ɔhaw ahorow. Ɛnyɛ obiara na onya wɔn. Nanso ɛho hia sɛ wohwɛ wɔn yiye.
| Sɛ wuhu saa sɛnkyerɛnne ahorow yi a, ka kyerɛ wo duruyɛfo ntɛm ara. | |
|---|---|
| Nneɛma a ɛma obi ho yɛ no hyew | Honam ani akisikuru, ɛyaw, anim, anofafa, tɛkrɛma anaa menewa a ɛho ahonhon. |
| Ntini a Ɛyɛ Fɛ (NMS) . | Atiridiinini a emu yɛ den, ntini a ɛyɛ den, fifiri a ɛboro so, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ, adwene a ɛyɛ basaa. |
| Nsɛnkyerɛnne a Ɛwɔ Akyi (EPS) . | Nipadua a ɛkeka ne ho a wontumi nni so, ntini a ɛyɛ den anaasɛ ɛtwetwe, wosow, ahomegye a enni hɔ, nantew a ɛyɛ den. |
| Mmerɛbo a ɛsɛe | Yafunu nifa atifi yaw, aduan ho akɔnnɔ a ɛyera, akisikuru, nsu a ɛyɛ kɔla a ɛyɛ hann, nsu a ɛyɛ kɔkɔɔ tuntum, honam ani anaa aniwa a ɛyɛ kɔkɔɔ. |
| Mogya mmoroso a ɛba fam | Adwene a ɛyɛ basaa, akisikuru, aniwa a ɛyɛ kusuu. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya ɔyare mmoawa | Atiridiinini, atiridiinini, ɔfe, menewam yaw. |
| Nsunsuanso bɔne a mpɛn pii no ɛnyɛ asiane, nanso sɛ ɛhaw adwene a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo | |
| Ayamtim | Ano a ɛyɛ nwunu |
| Dae a ɛma obi da | Mu duru a ɛkɔ soro |
Nkrasɛm a Wɔde Kɔ Fie
- Chlorpromazine yɛ aduru a ano yɛ den a ɛsɛ sɛ wɔnom wɔ nnuruyɛfo afotu ase nkutoo.
- Ka nnuru afoforo a wonom nyinaa ne ayaresa tebea foforo biara a wowɔ ho asɛm kyerɛ wo duruyɛfo.
- Mma nnyae nnuru a wobɛnom mpofirim da a wunni aduruyɛ mu afotu.
- Kwati sɛ wobɛka kar na woayɛ nnwuma a ɛsɛ sɛ woma w’ani da hɔ bere a worenom aduru no, efisɛ ebia nna ne adwenemhaw betumi aba.
- Kwati nsa koraa.
- Sɛ wunya ɔhaw biara a emu yɛ den te sɛ atiridiinini a ano yɛ den, ntini a ɛyɛ den, anaa nipadua a ɛkeka ne ho a wuntumi nni so a, kɔ oduruyɛfo nkyɛn ntɛm ara.
- Sɛ wonom nnuru pii a, kɔ ayaresabea dan a wɔhwɛ ntɛmpɛ so (ETU) ntɛm ara anaa kɔ National Poisons Information Center nkyɛn.
👩🏽 ⚕️ Nsɛmmisa foforo (FAQs)
💬 Chlorpromazine (Chlorpromazine / Thorazine) aduru ne yareɛ bɛn na ɛtwa toɔ?
Eyi yɛ aduru a tumi wom yiye a efi awo ntoatoaso a wɔanyinyin no mu (Typical antipsychotic / Phenothiazine) a wɔayɛ sɛ wɔde besiw adwenemyare a emu yɛ den a wɔfrɛ no ‘Schizophrenia’ no ano! Wɔmfa eyi mma obiara, wɔtaa de di dwuma ma ayarefo a wɔn ho yɛ den sen biara (Ayaresa-resistant) a wɔn adwenem naayɛ no ntumi nkɔ fam koraa ɛmfa ho nnuru afoforo nyinaa akyi. Wɔde ma nso de gyae hiccups ne akisikuru a emu yɛ den.
💬 Ɔkwan bɛn so na saa aduru yi (Chlorpromazine) du amemene no mu na eyi ɔyarefo no adwenem naayɛ ne nea ɔyɛ no ntɛmntɛm no fi hɔ?
Ade titiriw nti a adwenemyare a emu yɛ den ba ne nnuru a wɔfrɛ no ‘Dopamine’ a ɛkɔ soro dodo wɔ amemene no mu! Saa aduru yi siw/to dopamine receptors (D2 receptors) 100% bere a ɛhyɛn amemene no mu ara pɛ. Ɛyi nsusuwii a ɛyɛ kraman a ɛwɔ adwene mu no fi hɔ na ɛma ɔyarefo no dwo kodu baabi a ontumi ntutu ne nan/basa mpo (sedation).
💬 Nsunsuansoɔ titire bɛn na ɛsɛ sɛ nnipa a wɔnom saa aduru dedaw yi (Chlorpromazine) hwɛ yie wɔ ho?
Nneɛma bɔne pii wɔ hɔ! Asiane kɛse ne ‘ntini ne ntini a ɛyɛ mmerɛw (EPS/Tardive Dyskinesia)’. Ɛno kyerɛ sɛ sɛ wonom eyi a, akyinnye biara nni ho sɛ wubenya wo nan/nsa a wowosow a wuntumi nni so, tɛkrɛma bɛpue na woakyinkyim, na akyinnye biara nni ho sɛ wobɛyɛ den te sɛ robɔt. Afei nso, (Anticholinergic) ano no yɛ mmerɛw a wontumi nnyina ano, anisoadehu no yɛ kusuu, na sɛ wupue kɔ owia mu a, hokwan kɛse wɔ hɔ sɛ owia bɛhyew (Photosensitivity).
💬 Comments (0)
Wɔnnya nyɛɛ nsɛm biara. Fa wo nsɛm no ka ho wɔ ha nea edi kan.
Fa wo nsɛm no ka ho