So wobɛpɛ sɛ wuhu Lapatinib aduru a wɔde sa nufu mu kokoram ho asɛm?

Ebia wo duruyɛfo aka aduru bi a wɔfrɛ no Lapatinib ho asɛm akyerɛ wo, anaasɛ ebia w’adamfo bi de saa aduru yi redi dwuma. Yɛn nyinaa nim sɛ nufu mu kokoram a yɛbɛko atia no nyɛ mmerɛw. Enti, eyi yɛ mmɔden a wobɔ sɛ wubebua wo nsɛmmisa a ɛfa saa aduru yi ho, na woaka ho asɛm kɛkɛ.

Dɛn ne aduru yi a wɔfrɛ no Lapatinib?

Sɛ yɛbɛka no tiawa a, Lapatinib yɛ aduru a wɔde sa nufu mu kokoram . Ebia woresusuw sɛnea ɛyɛ adwuma no ho. Nea aduru yi yɛ ne sɛ kokoram nkwammoaa wɔ hɔ, na ɛma wɔn nyin brɛ ase kakra. Ɛte sɛ nea worebrɛ mmirikatufo bi ase. Afei kokoram no betumi atrɛw na anyin akodu baabi.

Ɛtɔ mmere bi a nnuruyɛfo betumi de saa aduru yi adi dwuma ama tebea afoforo, enti sɛ wowɔ nsɛmmisa foforo bi fa eyi ho a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo. Edin a agye din a wɔde frɛ saa aduru yi ne Tykerb.

Dɛn na ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na wode aduru yi adi dwuma?

Eyi ho hia paa. Ansa na wubefi ase de Lapatinib adi dwuma no, ɛsɛ sɛ woka w’akwahosan ho asɛm kyerɛ wo duruyɛfo. Efisɛ ebia ebehia sɛ wɔde ahwɛyiye kɛse ma nnipa binom a wɔwɔ nyarewa bi, anaasɛ ɛho behia sɛ wɔde ma wɔ ɔkwan foforo so. Hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ nea edidi so yi mu biara a:

• Koma mu yare: Sɛ wowɔ komayare bi, sɛ nhwɛso no, wo koma ayɛ mmerɛw, anaasɛ woadi kan anya komayare a.
• Koma a ɛbɔ anaa ɛbɔ daa: Sɛ koma no bɔ wɔ ɔkwan biako so na mmom ɛbɔ wɔ akwan horow so a.
• Mogya mmoroso: Sɛ wowɔ mogya mmoroso a.
• Sɛ magnesium dodow a ɛwɔ mogya no mu no sua a.
• Sɛ potassium dodow a ɛwɔ mogya no mu no sua a.
• Mmɛn mu yare: Sɛ wowɔ ɔhaw biara wɔ wo mmerɛbo ho a.
• Sɛ woadi kan anya adwene a ɛyɛ soronko (allergy) wɔ lapatinib, nnuru afoforo, nnuan, nnuru a wɔde yɛ nneɛma, anaa nneɛma a wɔde siesie nneɛma ho a.
• Sɛ woanyinsɛn anaa worebɔ mmɔden sɛ wubenyinsɛn a, eyi ho hia paa.
• Sɛ woyɛ ɛna a ɔma nufu a.

Sɛ woka saa nsɛm yi yiye a, oduruyɛfo no betumi asa wo yare dwoodwoo. Mfa biribiara nsie, sɛ ɛyɛ ketewa mpo a, ɛyɛ?

Ɔkwan bɛn so ankasa na wode saa aduru yi di dwuma?

Ɛho hia paa sɛ wubehu sɛnea wɔde saa aduru yi di dwuma pɛpɛɛpɛ. Ɛsɛ sɛ wofa no sɛnea wo duruyɛfo ka kyerɛ wo no pɛpɛɛpɛ, ne sɛnea wɔakyerɛw wɔ krataa no so no pɛpɛɛpɛ.

• Saa aduru yi yɛ aduru a wɔnom .
• Bɔ mmɔden sɛ wobɛnom bere koro mu da biara. Saa kwan no so no, aduru no bɛyɛ adwuma yiye wɔ wo nipadua mu.
• Saa nnuru yiMma nmmubu, ntwitwa, anaa nwe. Fa nsu mene tablet no nyinaa.
• Ɛho hia yiye sɛ wobɛnom saa aduru yi bere a wo yafunu da mpan . Ɛne sɛ, anyɛ yiye koraa no, dɔnhwerew biako ansa na wɔadidi anaasɛ wɔadi akyi. Efisɛ sɛ wode ka aduan ho a, ebia nipadua no rennye saa aduru yi nso.
• Kɔ so fa saa aduru yi di dwuma kosi sɛ wo duruyɛfo bɛka sɛ, "Ɛdɔɔso, gyae." Mma nnyae nom mpofirim, sɛ wo ho tɔ wo mpo a.

Ade foforo nso ne sɛ, nnom grapefruit nsu bere a worenom saa aduru yi. Grapefruit nsu betumi aka sɛnea aduru yi yɛ adwuma yiye. Enti, ɛbɛyɛ papa sɛ wobɛkwati.

So ɛsɛ sɛ wɔde aduru yi ma mmofra?

Ɛsɛ sɛ wɔhwɛ yiye titiriw bere a wɔde aduru yi rema mmofra no. Enti, sɛ oduruyɛfo no kamfo kyerɛ sɛ fa saa aduru yi ma wo ba a, wo ne no nkasa yiye na di akwankyerɛ no akyi pɛpɛɛpɛ.

Sɛ wonom nnuru pii a, dɛn na ɛsɛ sɛ woyɛ? (Nneɛma a wɔde ma boro so) .

Sɛ ɛba saa a, kyerɛ sɛ, sɛ wususuw sɛ woanom nnuru pii sen sɛnea wususuwii a, ɛsɛ sɛ wofrɛ beae a wɔhwɛ awuduru so anaa ayaresabea dan a ɛbɛn hɔ a wɔhwɛ ntɛmpɛ so ntɛm ara. Mma nsɛe bere.

Hyɛ no nsow a ɛho hia: Saa aduru yi yɛ ma wo nkutoo. Oduruyɛfo no akyerɛw ama wo tebea no nkutoo. Enti , mfa mma obi foforo, sɛ mpo wususuw sɛ wɔwɔ tebea koro no ara te sɛ wo a.

Na sɛ mepa dose bi nso ɛ?

Ɛtɔ da a, wo werɛ betumi afi, ɛnte saa? Sɛ wopa dose bi a, twa so. Fa dodow a edi hɔ no sɛnea wotaa yɛ no. Mfa nnuru abien prɛko pɛ da mfa nsiesie dodow a woayera no. Saa a wɔbɛyɛ no betumi ama wɔanom nnuru pii.

Nnuru afoforo bɛn na ɛnsɛ sɛ wɔde ka aduru yi ho, anaasɛ nnuru afoforo bɛn na ebetumi ne no adi nkitaho?

Eyi nso yɛ ɔfã bi a ɛsɛ sɛ wokenkan no yiye paa. Lapatinib betumi de ɔhaw aba bere a wɔde ka nnuru afoforo bi ho no. Ɛne sɛ, ɛnsɛ sɛ wɔde ka nnuru bi ho koraa, na ebetumi ne nnuru afoforo adi nkitaho.

Mfa Lapatinib nka nnuru a edidi so yi ho:

• Cisapride na ɔkyerɛwee
• Dronedarone a wɔfrɛ no Dronedarone
• Fluconazole a wɔde ma
• Pimozide a wɔde yɛ nnuru
• Posaconazole a wɔde ma
• Saquinavir a wɔde di dwuma
• Thioridazine a wɔde ma

Ebia saa nsɛm a wɔahyehyɛ yi nni mũ, enti ɛho hia sɛ wo ne wo duruyɛfo kasa fa eyi ho.

Afei nso, nnuru afoforo bi wɔ hɔ a ebetumi ne Lapatinib adi nkitaho. Ɛne sɛ, wobetumi aka sɛnea wɔn ho wɔn ho yɛ adwuma. Nhwɛso kakraa bi ni:

• Nnuru bi a wɔde kum HIV anaa AIDS.
• Nnuru bi a ekum ɔyare mmoawa, te sɛ Clarithromycin, Erythromycin, ne Telithromycin.
• Nnuru afoforo bi a ekum ɔyare mmoawa, sɛ nhwɛso no, Rifabutin, Rifampin, ne Rifapentine.
• Nnuru bi a wɔde sa adwenemhaw, dadwen, anaa adwenemyare afoforo.
• Nnuru bi a wɔde sa fungal yare, te sɛ Itraconazole, Ketoconazole, anaa Voriconazole.
• Nnuru bi a wɔde sa akisikuru te sɛ carbamazepine, phenobarbital, ne phenytoin.
• Dexamethasone a wɔde ma
• Digoxin a wɔde di dwuma
• Nefazodone a wɔde yɛ nnuru
• Nnuru foforɔ a ɛma koma no yɛ adwuma a ɛnteɛ (nnuru a ɛma QT ntam kwan kyɛ) - sɛ nhwɛsoɔ no, Dofetilide, Ziprasidone.
• St. John’s Wort (eyi yɛ nhabannuru) .

Saa nsɛm a wɔahyehyɛ yi nka nkitahodi ahorow a ebetumi aba nyinaa ho. Enti, ka nnuru a wonom nyinaa (a nnuru a wɔtɔn ka ho), nhabannuru, vitamin, ne aduannuru, ne sɛ wonom sigaret, wonom nsa, anaa wode nnuru foforo di dwuma ho asɛm kyerɛ wo duruyɛfo. Nneɛma bi betumi ne w’aduru no adi nkitaho.

Dɛn na ɛsɛ sɛ wohwɛ yiye wɔ ho bere a worenom aduru yi?

Ebia wobɛte nka sɛ wo ho nyɛ wo dɛ kakra na mpɛn pii no wo ho nyɛ wo den bere a worenom aduru yi no. Eyi yɛ ade a ɛfata. Nea enti a ɛte saa ne sɛ ɛnyɛ kokoram nkwammoaa nko na kokoram ayaresa (te sɛ nnuru a wɔde sa yare) betumi aka wɔn, na mmom nkwammoaa a wɔwɔ apɔwmuden nso. Enti, sɛ wunya ɔhaw biara a, ka kyerɛ wo duruyɛfo. Sɛ wote nka sɛ wo ho nyɛ wo dɛ mpo a, kɔ so nom aduru no kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae.

Ade a ɛho hia sen biara ne eyi:

• Nnyinsɛn bere a worenom aduru yi ne dapɛn biako bere a woagyae aduru no akyi. Sɛ woreyɛ nhyehyɛe sɛ wubenyinsɛn anaa wususuw sɛ ebia woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Ɛnsɛ sɛ mmarima nso bɔ mmɔden sɛ wɔbɛwo abofra bere a wɔrenom saa aduru yi, anaasɛ dapɛn biako bere a wɔagyae aduru no akyi. Saa aduru yi betumi de ɔhaw ahorow a emu yɛ den aba akokoaa a ɔhyɛ yafunu mu no so. Bisa wo duruyɛfo ma ɔmma no eyi ho nsɛm pii.
• Mma wo ba no nufu bere a worenom aduru yi, anaa dapɛn biako bere a woagyae aduru no akyi.

Ɛsɛ sɛ wohwɛ yiye paa wɔ saa nneɛma yi ho, efisɛ ebetumi aka abofra a ɔhyɛ yafunu mu akwahosan.

Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ aduru biara no, Lapatinib betumi de nsunsuanso bɔne bi aba. Ɛnyɛ obiara na onya bi, nanso nnipa binom nya bi. Enti eye sɛ wobɛma w’ani aku wɔn ho.

Nneɛma bɔne a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara:

Sɛ wuhu saa sɛnkyerɛnne ahorow yi mu biara a, ɛsɛ sɛ woka kyerɛ wo duruyɛfo anaa ayaresa kuw no ntɛm ara sɛnea wubetumi sɛ:

• Nneɛma a ɛma obi ho yɛ no hyew: Honam ani akisikuru, ɛyaw, akisikuru, anim, anofafa, tɛkrɛma, anaa menewa a ɛho ahonhon. Eyi betumi ayɛ nea egye ntɛmpɛ.
• Akisikuru: Sɛ wunya akisikuru mpɛn pii da biara a, ɛyɛ den.
• Koma mu nnyigyei sesa: Sɛ wo koma bɔ ntɛmntɛm anaasɛ ɛnte saa a, wote nka sɛ wo ho yɛ wo yaw, wototɔ piti, wo koko yɛ wo yaw, anaasɛ ɛyɛ den sɛ wobɛhome.
• Mmɛn mu opira: Ɛyaw wɔ yafunu no nifa so atifi, aduan ho akɔnnɔ a ɛyera, akisikuru, nsu a ɛyɛ fitaa, nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum, ne ɔbrɛ anaa mmerɛwyɛ soronko.
• Kɔkɔkɔɔ, akisikuru, honam ani a ɛbɛpae anaasɛ ayɛ mmerɛw nso betumi aba wɔ ano no mu.
• Asen, nsa, anaa anan a ɛho ahonhon.
• Ɔhaw a ɛba wɔ ɔhome mu.

Sɛ wuhu biribi te sɛ eyi a, akyinnye biara nni ho sɛ ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara.

Nsunsuanso bɔne a mpɛn pii no ɛho nhia sɛ woka kyerɛ wo duruyɛfo (nanso ɛsɛ sɛ woka kyerɛ wo duruyɛfo (nanso ɛsɛ sɛ woka kyerɛ sɛ ɛkɔ so):

Mpɛn pii no, nsunsuanso bɔne a wɔabobɔ din wɔ ase ha no nyɛ aniberesɛm. Nanso, sɛ wɔkɔ so anaasɛ wɔhaw wo pii a, ka kyerɛ wo duruyɛfo.

• Ɛwa
• Akɔnnɔ
• Abofono
• Ɛyaw, kɔkɔɔ, anaa ɔfe a akuru wɔ ano anaa menewa mu
• Ɔfe a wɔfe

Saa nsɛm a wɔahyehyɛ yi nyɛ nea ebetumi afi mu aba nyinaa. Sɛ wuhu biribi foforo a ɛyɛ soronko a, wo ne wo duruyɛfo nka ho asɛm.

Ɛhe na ɛsɛ sɛ mede saa aduru yi sie?

Eyi nso ho hia. Sɛ wɔankora nnuru so yiye a, sɛnea etu mpɔn no so betumi atew.

• Fa sie baabi a mmofra ne afieboa ntumi nkɔ hɔ.
• Fa sie wɔ dan mu hyew, digrii Celsius 20 kosi 25 (digrii Fahrenheit 68 kosi 77). Mfa nneɛma nsie wɔ mmeae a ɛhɔ yɛ hyew anaasɛ ɛhɔ yɛ nwini kɛse.
• Mfa nnuru a ne bere atwam nni dwuma. Tow wɔn gu.

Ɔkwan bɛn so na wotow nnuru a wɔmfa nni dwuma ne nea ne bere atwam gu?

Ɛnyɛ bere nyinaa na nnuru a wobɛtow agu nwura mu anaasɛ wobɛhohoro akɔ tiafi mu ara kwa no nyɛ adwene pa. Ebetumi apira nneɛma a atwa yɛn ho ahyia nso.

• Ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wode nnuru no bɛkɔ baabi a wɔayɛ nhyehyɛe a wɔde bɛsan de nnuru no akɔ. Wubetumi abisa wo nnurutɔnbea anaa polisifo mmeae a ɛtete saa ho asɛm.
• Sɛ ɔkwan biara nni hɔ a wɔbɛfa so de ama a, .Hwɛ nnuru a wɔakyerɛw so anaa krataa a ɛka ho no mu hwɛ sɛ akwankyerɛ bi wɔ hɔ a ɛkyerɛ sɛ ebia wobɛtow agu nwura mu anaasɛ wobɛhohoro akɔ tiafi mu anaa.
• Sɛ wuntumi nhu a, bisa wo duruyɛfo anaa nnuruyɛfo.
• Sɛ ɛka sɛ ɛyɛ nea asiane biara nni ho sɛ wobɛtow agu nwura mu a, yi aduru no fi ade no mu na fa fra biribi foforo a mfaso nni so, te sɛ mpataa nwura, dɔte, anaa kɔfe a wɔayam. Afei, fa afrafrade no gu kotoku anaa ade mu, tow ano, na tow gu nwura mu. Eyi remma obi foforo nnye na ɔde bedi dwuma.

Ade a ɛho hia sen biara a ɛsɛ sɛ wode sie w’adwenem (Take-Home Message) .

Okay, enti yɛaka saa aduru yi ho asɛm pii, Lapatinib, ɛnte saa? Nea etwa to no, ma menbɔ nneɛma a ɛho hia paa a ɛsɛ sɛ wokae no bi mua.

Kokoram a wɔko no nyɛ mmerɛw. Nanso, ɛho hia paa sɛ wubehu nsɛm a ɛfata, di wo nnuruyɛfo afotu akyi pɛpɛɛpɛ, na wokɔ so nya akokoduru. Lapatinib yɛ aduru a ebetumi aboa wo wɔ saa ɔko no mu.

• Fa aduru no sɛnea oduruyɛfo no ka no pɛpɛɛpɛ, wɔ bere a ɛfata mu, wɔ dodow a ɛfata mu. Kae sɛ wobɛfa no yafunu a hwee nni mu na ɛnyɛ sɛ wode bobe nsu bɛfa.
• Ka nnuru afoforo, nhabannuru, ne nnuru a wɔde ka ho a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo , efisɛ ebia nneɛma bi ne saa aduru yi bedi nkitaho.
• Sɛ woanyinsɛn, woreyɛ nhyehyɛe anyinsɛn, anaa worenom nufu a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo. Hwɛ yiye paa bere a worenom aduru yi ne dapɛn biako bere a woagyae no.
• Hwɛ nneɛma bɔne a efi mu ba no yiye. Sɛ wuhu biribi a ɛte sɛ nea anibere wom a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Sɛ wowɔ nsɛmmisa anaa adwenem naayɛ bi a, mfa nsie wo ho, na mmom bisa wo duruyɛfo anaa nnuruyɛfo.

Yɛpɛ sɛ wo ho tɔ wo ntɛm! Tra hɔ pintinn!

` Lapatinib, Nufu mu Kokoram, Kokoram Aduru, Nsunsuanso bɔne, Tykerb, Kokoram Ayaresa