Ɛtɔ da bi a, sɛ yɛnom nnuru a ano yɛ den a wɔde kum ɛyaw, anaa opioid, a nnuruyɛfo akyerɛw ama yɛn wɔ ɔhaw bi a emu yɛ den ho, wɔ oprehyɛn akyi, anaasɛ ɛyaw a ɛkɔ so ho a, yewie a, yehyia ɔhaw foforo, ɛnte saa? Ɛno ne akisikuru . Wɔ nnipa binom fam no, eyi yɛ ahometew araa ma wontumi nnidi anaa wɔnnom mpo. Enti ɛnnɛ yɛbɛka injection soronko bi a ɛboa ma akisikuru a opioids de ba no ho asɛm. Ɛno yɛ aduru bi a wɔfrɛ no methylnaltrexone.
Dɛn ne aduru yi a wɔfrɛ no methylnaltrexone? Ɔkwan bɛn so na ɛyɛ adwuma?
Afei ma yɛnhwɛ nea aduru a wɔfrɛ no methylnaltrexone yi yɛ ankasa ne sɛnea ebetumi aboa wo. Sɛ yɛbɛka no tiawa a, wɔayɛ no pɔtee sɛ wɔde bɛsa akisikuru a opioid a wonom de yɛ ɛyaw no de ba no.
Susuw ho hwɛ, opioids a wonom no betumi atew ɛyaw so ankasa. Ɛno yɛ nokware. Nanso wɔma wo dwensɔtwaa nso brɛ ase, na ɛma wo dwensɔtwaa yɛ ‘ɔkwasea’ kakra. Ahoɔhare a nsu a ɛwɔ wo dwensɔtwaa mu no brɛ ase. Ɛno ne bere a dwensɔtwaa kyɛ, ɛtɔ mmere bi a ɛtra hɔ nna pii, anaasɛ ɛyɛ den yiye.
Enti, saa methylnaltrexone aduru yi yɛ ade a ɛyɛ nwonwa ankasa. Ɛsiw saa opioid ahorow no nkɛntɛnso ano wɔ wo dwensɔtwaa mu, a ɛne sɛ ɛbɛma dwensɔtwaa no agyae adwumayɛ. Nanso, adeɛ a ɛho hia paa ne sɛ, ɛnkɔ w’amemene mu nkɔyi ɛyaw no mfi hɔ. Ɛyɛ adwuma wɔ wo dwensɔtwaa so tẽẽ kɛkɛ. Afei ntini a ɛwɔ wo dwensɔtwaa mu no fi ase yɛ adwuma yiye bio, na ɛboa ma wofa nsu mu. Mpɛn pii no, wubetumi ahu nea efi mu ba no wɔ dɔnhwerew fã mu. Yɛfrɛ saa aduru yi ‘opioid blocker’ . Ɛne sɛ, esiw opioid ahorow no nneyɛe bi ano, titiriw nkɛntɛnso a enya wɔ dwensɔtwaa so no.
Ɛtɔ mmere bi a, nnuruyɛfo betumi akyerɛw saa aduru yi ama wo wɔ tebea afoforo ho, enti sɛ wowɔ nsɛmmisa bi a, bisa wo duruyɛfo anaa nnuruyɛfo no. Saa aduru yi nso ba wɔ brand din `(Relistor)` ase.
Nneɛma bɛn na ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom saa aduru yi?
Ansa na wubefi ase anom methylnaltrexone no, ɛho hia sɛ wode w’akwahosan ho nkyerɛkyerɛmu a edi mũ ma wo duruyɛfo. Eyi te saa efisɛ ɛno ansa na wubetumi ahu sɛ saa aduru yi fata wo anaa. Nneɛma bi a ɛsɛ sɛ wuhu ampa ni:
- Sɛ wowɔ asaabo mu yare a . Esiane sɛ woyi nnuru pii fi nipadua no mu denam asaabo so nti, sɛ wowɔ asaabo mu haw a, ɛsɛ sɛ wususuw nnuru no dodow ho yiye.
- Sɛ wowɔ mmerɛbo mu yare a . Mmɛn nso yɛ akwaa titiriw bi a ɛtew yɛn nipadua ho fi nnubɔne ho. Enti sɛ mmerɛbo mu haw bi wɔ hɔ a, ɛsɛ sɛ yɛka ɛno nso ho asɛm.
- Biribi a enye wɔ wo yafunu anaa wo dwensɔtwaa mu?Sɛ ɛwɔ hɔ a. Sɛ nhwɛso no, sɛ dwensɔtwaa no siw, akuru, anaa tebea foforo a emu yɛ den a. Esiane sɛ saa aduru yi ma dwensɔtwaa no dwumadi yɛ kɛse nti, ebia ɛremfata nnipa a wɔwɔ tebea horow a ɛte saa.
- Sɛ wo ho ayɛ wo hyew wɔ methylnaltrexone, nnuru foforo biara, aduan, nnuru a wɔde yɛ nneɛma, anaa nneɛma a wɔde siesie nneɛma ho a.
- Sɛ woanyinsɛn anaa worebɔ mmɔden sɛ wubenyinsɛn a, ɛho hia sɛ wo ne wo duruyɛfo kasa ansa na woanom aduru biara saa bere yi.
- Sɛ woyɛ ɛna a ɔma nufu a, ɛsɛ sɛ wuhu nso sɛ nnuru bi betumi afa nufusu so akɔ wo ba no nkyɛn.
Ɛnyɛ saa nneɛma yi nko, na mmom ɛho hia paa nso sɛ wobɛka akwahosan ho haw biara a wowɔ ne nnuru foforo biara a wonom ho asɛm kyerɛ wo duruyɛfo.
Ɔkwan bɛn so na mede saa aduru yi di dwuma? Ɔkwan bɛn na eye sen biara?
Wɔde saa aduru yi a wɔfrɛ no methylnaltrexone ma sɛ aduru a wɔde twitwiw honam ani . Wɔtaa de ma wɔ ayaresabea anaa ayaresabea.
Nanso, ɛtɔ mmere bi a, ebia ɛsɛ sɛ wode saa aduru yi ma wo ho wɔ fie. Sɛ ɛba saa a, mma ɛnhaw wo. Wo duruyɛfo anaa ɔyarehwɛfo bɛkyerɛ wo sɛnea wosiesie, sɛnea wode twitwiw wo honam ani, ne sɛnea wobɛyɛ no yiye pɛpɛɛpɛ. Ɛsɛ sɛ woyɛ no sɛnea wɔka kyerɛ wo no pɛpɛɛpɛ, wɔ nhyehyɛe koro no ara mu pɛpɛɛpɛ. Ɛnyɛ adwene pa sɛ wobɛnom mpɛn pii anaa mpɛn pii sen sɛnea oduruyɛfo no bɛka akyerɛ wo.
Nea ɛho hia sen biara ne sɛ, so ɛnsɛ sɛ wode wo nnade ne wo syringe a wode adi dwuma no gu nwura mu? Ade titiriw bi wɔ hɔ a wɔde nneɛma a ano yɛ nnam gu mu ma ɛno. Wubetumi abisa wɔ wo nnurutɔnbea anaa oduruyɛfo nkyɛn. Ɛhɔ na ɛsɛ sɛ wode nneɛma a wɔde adi dwuma yi gu. Eyi yɛ yɛn nyinaa ahobammɔ na yɛakwati sɛ yɛde afoforo bɛto asiane mu.
Sɛ wɔkyerɛw wo saa aduru yi a, nnurutɔnbea no bɛma wo nsɛm kratasin titiriw bi a wɔfrɛ no ``MedGuide'' . Wɔde eyi ma wo bere biara a wubenya aduru foforo, bere mpo a woasan ahyɛ mu ma no. Ɛwɔ aduru no ho nsɛm a ɛho hia pii. Enti, ɛho hia paa sɛ wokenkan no yiye.
Ɛsɛ sɛ wɔhwɛ yiye titiriw bere a wɔde saa aduru yi rema mmofra no . Enti, sɛ wopɛ sɛ wode saa aduru yi ma wo ba a, wo ne wo duruyɛfo nka ho asɛm yiye na di wɔn akwankyerɛ akyi.
Sɛ wonom nnuru pii a, dɛn na ɛsɛ sɛ woyɛ? (Nneɛma a wɔde ma boro so) .
Sɛ wususuw sɛ woanom aduru yi dodo a, frɛ beae a ɛko tia awuduru anaa baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ a ɛbɛn wo ntɛm ara. Sɛ ɛnte saa a, kɔ ntɛm ara.
Kae sɛ saa aduru yi yɛ wo nkutoo dea. Mfa saa aduru yi nkyerɛ afoforo da.
Na sɛ mepa dose bi nso ɛ?
Eyi nyɛ aduru a wɔtaa nom bere koro mu da biara. Ɛne sɛ, ɛnyɛ aduru a wɔde di dwuma daa. Wɔde ma sɛnea ɛho hia. Enti, ɛho nhia sɛ wohaw wo ho sɛ wobɛpa nnuruyɛ ho nhyehyɛe. Nanso, sɛ wowɔ nsɛmmisa bi fa sɛnea wo duruyɛfo aka akyerɛ wo sɛ fa di dwuma ho a, bisa.
Nneɛma foforo bɛn na ebetumi ne aduru yi adi nkitaho? (Nkitahodi ahorow) .
Nnuru bi wɔ hɔ a sɛ wɔde methylnaltrexone ka ho a, ebetumi de ɔhaw aba. Nhwɛsoɔ:
- Alvimopan na ɔkyerɛwee
- Naloxone a wɔde yɛ aduru
- Naltrexone a wɔde ma
Saa list yi nwie pɛyɛ. Ebia nnuru afoforo nso wɔ hɔ. Enti, ka nnuru a wonom (sɛ́ ebia nnuruyɛfo afoforo akyerɛw ama wo anaasɛ wotɔ wɔ nnurutɔnbea), nhabannuru, vitamin, ne aduannuru a wode di dwuma nyinaa ho asɛm kyerɛ wo duruyɛfo. Afei nso, sɛ wonom sigaret, wonom nsa, anaa wode nnubɔne foforo a mmara mma ho kwan di dwuma a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo . Nneɛma bi betumi ne aduru yi adi nkitaho na ɛde ɔhaw ahorow aba.
Dɛn na ɛsɛ sɛ yɛhwɛ yiye wɔ ho titiriw bere a yɛrenom aduru yi?
Nneɛma kakraa bi wɔ hɔ a ɛsɛ sɛ wohwɛ yiye wɔ ho bere a wode aduru yi redi dwuma no:
- Sɛ wofa saa aduru yi wie a, tena baabi a wubetumi akɔ tiafi ntɛm ara sɛnea wubetumi. Ebia ɛho behia sɛ wohohoro wo ho bere a woanom aduru yi akyi bere tiaa bi. Ɛtɔ mmere bi a, ebetumi aba mpofirim.
- Bere a worenom saa aduru yi no, w’aduruyɛfo kuw no bɛhwɛ wo tebea no yiye. Sɛ wo yare no ho sɛnkyerɛnne no ankɔ yiye, anaasɛ sɛ ɛyɛ kɛse a, ka kyerɛ wo duruyɛfo anaa ɔyarehwɛfo ntɛm ara.
- Ebia wobɛte nka sɛ woada kakra anaasɛ w’adwene atu afra bere a woanom aduru yi awie no. Enti, kosi sɛ wubehu sɛnea aduru yi ka wo ankasa no, kwati sɛ wobɛka kar, wode mfiri bedi dwuma, anaasɛ wobɛyɛ biribiara a ɛhwehwɛ sɛ wode w’adwene si biribi so.
- Nnyina hɔ anaa ntra ase mpofirim. Hwɛ yiye titiriw sɛ woabɔ akwakoraa a. Saa a wobɛyɛ no betumi ama wo ho ayɛ wo yaw na wubetumi ahwe ase.
- Kwati nsa a wobɛnom. Nsã betumi asiw aduru yi a etu mpɔn no kwan.
Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba? (Nsunsuanso bɔne) .
Te sɛ aduru biara no, methylnaltrexone betumi de ɔhaw ahorow bi aba. Nanso, ɛnyɛ obiara na onya bi. Ebinom yɛ aniberesɛm, na ebinom nso nyɛ aniberesɛm saa.
Nneɛma bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara:
Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, ka kyerɛ w’akwahosan kuw no ntɛm ara sɛnea wubetumi:
- Nneɛma a ɛma obi ho yɛ no hyew:Honam ani akisikuru, ɛyaw, sɛnkyerɛnne a ɛte sɛ akisikuru, anim, anofafa, tɛkrɛma, ne menewa a ɛho ahonhon. Eyinom betumi ayɛ nea asiane wom kɛse.
- Yafunu mu yaw a emu yɛ den: Eyi kyerɛ sɛ ɛyaw no mu yɛ den, ɛkɔ so, na ɛkɔ soro sen yafunu mu yaw a ɛyɛ daa.
Nsunsuanso bɔne a mpɛn pii no enhia sɛ wunya aduruyɛ mu afotu, nanso sɛ ɛkɔ so anaasɛ ɛhaw adwene a, ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ:
Mpɛn pii no, eyinom kɔ wɔ nna kakraa bi mu. Nanso, sɛ wɔkɔ so na ɛhaw wo a, ka kyerɛ wo duruyɛfo sɛ:
- Awɔw a wɔte nka (Chills) .
- Ayamtuo
- Fifiri a ɛboro so
- Tipaeɛ
- Abofono
- Yafunu mu yaw (a ɛnyɛ pɔtee) .
Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhu biribi foforo biara a wɔankyerɛw a, wo ne wo duruyɛfo nka ho asɛm. Wubetumi abɔ FDA amanneɛ wɔ nea efi mu ba no ho wɔ 1-800-FDA-1088.
Ɔkwan bɛn so na wɔde aduru yi sie? (Akoraeɛ)
Ɛho hia paa nso sɛ wode nnuru sie yiye.
- Fa saa aduru yi sie baabi a mmofra ne afieboa ntumi nkɔ hɔ.
- Fa sie wɔ dan mu hyew (a ɛyɛ digrii Celsius 20 kosi 25, digrii Fahrenheit 68 kosi 77) . Mfa sie baabi a awɔw wom kɛse (te sɛ nea ɛwɔ frigye mu). Afei nso, bɔ wo ho ban fi hann ho.
- Mfa nnuru a ne bere atwam nni dwuma. Tow gu sɛnea ɛsɛ.
Saa kratawa yi yɛ nsɛm a wɔaboaboa ano kɛkɛ. Ebia nsɛm a wuhia nyinaa nni mu. Sɛ wowɔ nsɛmmisa foforo biara fa saa aduru yi ho a, yɛsrɛ wo ne wo duruyɛfo, nnuruyɛfo, anaa akwahosan ho ɔyaresafo foforo nkasa.
Nneɛma a ɛho hia sen biara a ɛsɛ sɛ wokae (Take-Home Message) .
Okay, enti, yɛbɛsan akae wo nneɛma a ɛho hia sen biara a ɛsɛ sɛ wokae fi nea yɛaka ho asɛm no mu?
1. Methylnaltrexone yɛ aduru titiriw a wɔde twitwiw akisikuru a opioid (nnuru a wɔde kum ɛyaw) de ba.
2. Eyi yɛ adwuma wɔ dwensɔtwaa nkutoo so, enni nnuru a wɔde kum ɛyaw so nkɛntɛnso biara.
3. Hwɛ hu sɛ wobɛka nyarewa foforo biara a wowɔ ne nnuru biara a wonom ho asɛm akyerɛ wo duruyɛfo.
4. Fa injection no di dwuma sɛnea wo duruyɛfo ka kyerɛ wo no pɛpɛɛpɛ. Tow nnade a wode adi dwuma no gu dwoodwoo.
5. Tra bɛn tiafi bere a woanom aduru no awie no. Hwɛ yiye wɔ nna ne adwenemhaw ho, efisɛ eyi betumi aba.
6. Sɛ wo yafunu mu yɛ wo yaw kɛse anaasɛ wo ho yɛ wo hyew a, ka kyerɛ wo duruyɛfo ntɛm ara.
Mewɔ anidaso sɛ wubehu sɛ mfaso wɔ saa nsɛm yi so. Kɔ so nya apɔwmuden!
` Methylnaltrexone, Methylnaltrexone, opioid akisikuru, akisikuru aduru, Relistor, nnuru no mu nsunsuanso bɔne, injection
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