Momma yensua Natalizumab vaccine no ho ade. So wɔakyerɛw aduru yi nso ama wo?

Sɛ oduruyɛfo kamfo nnuru a wɔde bɔ wo ho ban a wɔfrɛ no Natalizumab kyerɛ wo anaa obi a wunim no a, ɛyɛ ade a ɛfata sɛ wubenya nsɛmmisa pii wɔ ho. "Ɔyare bɛn na wɔde eyi ma?", "So ɛbɛsa ampa?", "So nsunsuanso bɔne bi wɔ hɔ?" Ebia woresusuw asɛm koro no ara ho. Enti, ɛnnɛ, momma yɛnka aduru yi a wɔfrɛ no Natalizumab ho asɛm wɔ ɔkwan tiawa bi so a wubetumi ate ase.

Aduru bɛn na Natalizumab yɛ?

Sɛ yɛbɛka no tiawa a, Natalizumab yɛ aduru. Ɛne sɛ, ɛnsa yare no koraa, nanso ɛboa ma wodi yare no ho sɛnkyerɛnne ahorow so na ɛtew mpɛn dodow a ɛyɛ hyew no so. Wɔde saa aduru yi di dwuma titiriw ma tebea abien.

1. Wɔ tebea a ɛne Relapsing Multiple Sclerosis ho no:

Susuw ho saa kwan yi so: yɛn ntini ahorow te sɛ waya a ɛde anyinam ahoɔden nsɛnkyerɛnne kɔ. Wɔ yare bi a wɔfrɛ no multiple sclerosis mu no, ade a ɛbɔ ho ban (myelin) a atwa ntini ahorow yi ho ahyia no sɛe. Afei saa anyinam ahoɔden nsɛnkyerɛnne no ntumi nkɔ yiye. Eyi betumi de sɛnkyerɛnne ahorow te sɛ nantew a ɛyɛ den, aniwa mu haw, kasa a ɛyɛ den, ne adwenem naayɛ aba. Natalizumab yɛ adwuma denam saa ɔsɛe yi a ɛhyɛ so na ɛtew mpɛn dodow a yare no mu yɛ den no so.

2. Wɔ Crohn yare no ho:

Crohn yare no yɛ ɔyare a enni sabea a ɛma aduan mu yɛ hyew, titiriw dwensɔtwaa. Ebetumi de sɛnkyerɛnne ahorow te sɛ yafunu mu yaw, akisikuru, ne mu duru a ɛso tew aba. Ebia nnuruyɛfo bɛkamfo aduru Natalizumab akyerɛ bere a ayaresa afoforo anyɛ adwuma no.

Nea ɛho hia sen biara ne sɛ wo duruyɛfo besi gyinae sɛ ebia saa aduru yi fata wo ne bere tenten a ɛsɛ sɛ wonom. Enti, ɛho hia paa sɛ yedi n’akwankyerɛ so.

Nnuruyɛfo betumi de saa aduru yi nso adi dwuma wɔ tebea afoforo mu. Sɛ wowɔ nsɛmmisa bi fa ho a, bisa wo duruyɛfo anaa nnuruyɛfo. Aduru yi din ne Tysabri.

Dɛn na ɛsɛ sɛ meka kyerɛ oduruyɛfo no ansa na manom saa aduru yi?

Ansa na wobɛhyɛ aseɛ anom Natalizumab no, ɛho hia sɛ woka nsɛm bi kyerɛ w’akwahosan kuo (i.e., nnuruyɛfoɔ ne ayarehwɛfoɔ), ɛfiri sɛ saa nsɛm no bɛboa wɔn ama wɔasi gyinaeɛ sɛ saa aduru yi fata wo anaa sɛ ɛhia sɛ woyɛ ahwɛyie soronko biara.

Sɛ wowɔ saa nneɛma yi a, akyinnye biara nni ho sɛ ka saa:

• Nkwammoaa a ɛko tia nyarewa ho haw: Sɛ wowɔ mmerɛwyɛ anaa ɔhaw bi wɔ wo nipadua a ɛko tia nyarewa (immune system) ho a, ka ho asɛm kyerɛ yɛn. Nea enti a ɛte saa ne sɛ saa aduru yi nso ka nipadua no mu tumi a ɛko tia nyarewa no, enti ɛho hia sɛ yɛma yɛn ani da hɔ.
• Tebea bi a wɔfrɛ no Progressive Multifocal Leukoencephalopathy (PML): Ɔyare bi a wɔfrɛ no Progressive Multifocal Leukoencephalopathy (PML): Ɔyare bi a wɔfrɛ no Progressive Multifocal Leukoencephalopathy.Eyi yɛ amemene mu yare a ɛntaa nsi koraa nanso ɛyɛ hu yiye. Sɛ woanya saa tebea yi pɛn a, ɛsɛ sɛ woka kyerɛ yɛn.
• Sɛ wo ho yɛ wo hyew wɔ Natalizumab anaa nnuru afoforo, nnuan, nnuru a wɔde yɛ nneɛma, anaa nneɛma a wɔde siesie nneɛma ho a: Nnipa binom betumi ayɛ wɔn ayayade wɔ nnuru bi ho. Enti sɛ woadi kan anya aduru yi anaa aduru foforo biara ho adwenemhaw bi a, ka kyerɛ wo duruyɛfo.
• Sɛ woanyinsɛn anaa worebɔ mmɔden sɛ wubenyinsɛn a: Nnuru bi betumi apira akokoaa no bere a wanyinsɛn no, enti ɛho hia sɛ wo ne wo duruyɛfo kasa fa eyi ho.
• Sɛ woyɛ ɛna a ɔma nufu a: Nnuru bi betumi afa nufusu so akɔ wo ba no nkyɛn. Enti ka eyi nso ho asɛm kyerɛ wo duruyɛfo.

Wɔ saa nneɛma yi akyi no, ɛho hia yiye nso sɛ wobɛka nnuru foforo biara a worenom (a wɔakyerɛw ama wo, a wontɔn, aduru a wɔde di dwuma wɔ amanne kwan so, vitamin, nhabannuru) ho asɛm kyerɛ wo duruyɛfo.

Wode saa aduru yi di dwuma dɛn?

Wɔde natalizumab ma sɛ aduru a wɔde hyɛ ntini bi mu. Ɛte sɛ nea wode nkyene aduru bi ama. Worentumi nyɛ eyi wɔ fie. Akwahosan ho ɔbenfo te sɛ oduruyɛfo anaa ɔyarehwɛfo na ɔde ma wo wɔ ayaresabea anaa ayaresabea.

Wɔtaa de saa aduru yi ma bɛyɛ pɛnkoro ɔsram biara, nanso eyi betumi ayɛ soronko a egyina wo tebea so.

Sɛ wɔkyerɛw wo saa aduru yi a, nnurutɔnbea no bɛma wo akwankyerɛ titiriw bi (MedGuide) . Wo nsa bɛka eyi wɔ aduru biara a wɔakyerɛw ama wo mu, bere biara a wubenya aduru no. Ɛho hia paa sɛ wokenkan eyi yiye. Ekura nsɛm a ɛfa aduru no, nea efi mu ba, ne nneɛma a ɛsɛ sɛ yɛhwɛ yiye wɔ ho. Sɛ biribi wɔ hɔ a wonte ase a, nsuro sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo.

So wobetumi de saa aduru yi ama mmofra?

Mpɛn pii no, wɔmpene so sɛ wɔmfa saa aduru yi nni dwuma wɔ mmofra mu. Sɛ woresusuw saa aduru yi ho ama wo ba a, ɛsɛ sɛ wo ne wo mmofra oduruyɛfo kasa fa ho.

Sɛ wonom nnuru pii a, dɛn na ɛsɛ sɛ woyɛ? (Nneɛma a wɔde ma boro so) .

Esiane sɛ wɔde eyi ma wɔ ayaresabea nti, hokwan a ɛwɔ hɔ sɛ eyi bɛba no sua. Nanso, sɛ wususuw sɛ woanom nnuru pii a, frɛ baabi a wɔhwɛ awuduru so anaa baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ ntɛm ara.

Saa aduru yi yɛ ma wo nkutoo! Eyi yɛ biribi a oduruyɛfo no akyerɛw ama wo tebea no ne wo nipadua. Enti, nkyɛ saa aduru yi nkyerɛ obi foforo da.

Sɛ wopa nnuru dodow bi a, dɛn na woyɛ?

Ɛho hia paa sɛ wobɛnom saa aduru yi wɔ bere ano. Sɛ wopa bere a woahyɛ da ayɛ ho nhyehyɛe a, frɛ wo duruyɛfo anaa akwahosan ho ɔbenfo ntɛm ara. Wɔbɛkyerɛ wo nea ɛsɛ sɛ woyɛ akyi. Mma w’ankasa nsi gyinae.

Nnuru afoforo bɛn na ebetumi ne saa aduru yi adi nkitaho (abɔ abira)?

Eyi yɛ asɛm a ɛho hia paa. Nnuru bi wɔ hɔ a ebetumi de ɔhaw aba bere a wɔde ka Natalizumab ho no. Enti, ɛho hia sɛ wo duruyɛfo hu nnuru a wonom nyinaa.

Mfa Natalizumab nka nnuru a edidi so yi ho:

• Nnuru a wɔde abɔde a nkwa wom te sɛ adalimumab, certolizumab, etanercept, golimumab, ne infliximab nso ka nipadua no mu tumi a ɛko tia nyarewa no, enti ebetumi ama asiane a ɛwɔ hɔ sɛ obi benya ɔyare mmoawa a emu yɛ den no ayɛ kɛse.

Saa nnuru yi nso betumi ne Natalizumab adi nkitaho:

• Azathioprine a wɔde di dwuma
• Cyclosporine a wɔde di dwuma
• Nneɛma a wɔde hyɛ nipadua mu
• 6-mercaptopurine a wɔde di dwuma
• Methotrexate a wɔde di dwuma
• Nnuru afoforo a ɛma hokwan a wowɔ sɛ wobɛko atia ɔyare mmoawa no so tew
• Steroid nnuru - nhwɛsoɔ: prednisone anaa cortisone
• Vaccines - Hwɛ yie berɛ a worenya vaccines a nkwa wom, titire. Wo ne wo duruyɛfo nka eyi ho asɛm.

Ebia nnuru a wɔde di dwuma no nyinaa nka saa nsɛm a wɔahyehyɛ yi ho. Enti, ka nnuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo (a nhabannuru, nnuru a wɔmfa nnuru nkyerɛw, ne nnuru a wɔde ka aduan ho ka ho), ne sɛ wonom sigaret, wonom nsa, anaa wode nnubɔne a mmara mma ho kwan di dwuma a. Nneɛma bi betumi ne wo nnuru no adi nkitaho.

Nneɛma bɛn na ɛsɛ sɛ yɛhwɛ yiye wɔ ho bere a yɛrenom aduru yi?

Bere a worenom saa aduru yi no, wo duruyɛfo bɛhwɛ wo daa. Hwɛ hu sɛ wobɛkɔ wo duruyɛfo nkyɛn wɔ nna a wɔahyɛ ato hɔ no mu. Sɛ wo yare no ho sɛnkyerɛnne no ankɔ yiye, sɛ ɛyɛ kɛse, anaa sɛ ɛkɔ so tra hɔ a, ka kyerɛ wo duruyɛfo.

Twe wo ho fi nnipa a wɔyare ho. Saa aduru yi betumi aka wo nipadua mu ahoɔden a ɛko tia nyarewa no kakra, na ama woanya nyarewa. Sɛ wunya yare no ho sɛnkyerɛnne te sɛ atiridiinini, atiridiinini, menewa mu yaw, anaa hwene a ɛretu a, frɛ wo duruyɛfo ntɛm ara na ɔmmoa wo. Mma wo nkutoo mfi adi nkɔpɛ nnuru.

Kɔkɔbɔ a ɛho hia yiye: asiane a ɛwɔ hɔ sɛ obi benya amemene mu yare (PML) .

Ebia eyi bɛyɛ te sɛ nea ɛyɛ hu kakra, nanso ɛho hia sɛ wohu. Wɔ ayarefo binom fam no, ɛwom sɛ ɛntaa nsi koraa de, nanso aduru Natalizumab betumi ama amemene mu yare a emu yɛ den a wɔfrɛ no Progressive Multifocal Leukoencephalopathy (PML) . Eyi betumi akum obi mpo.

Enti, sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara sɛ:

• Anisoadehu mu nsakrae (e.g., anisoadehu a ɛyɛ kusuu mpofirim, anisoadehu mmɔho abien) .
• Adwene mu nsɛnnennen (sɛ nhwɛso no, basabasayɛ, nkae a wɔhwere, gyinaesi a ɛyɛ den) .
• Ɔkasa mu nsɛnnennen (e.g., nsɛmfua a ɛyɛ mmerɛw, a ontumi nkasa pefee) .
• Nantew a ɛyɛ den (sɛ nhwɛso no, sɛ obi kari pɛ, ontumi nnantew yiye) .
• Ɛyɛ den sɛ wubegyina hɔ

Sɛ wuntumi nkɔ wo duruyɛfo nkyɛn a, kɔ baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ mu ntɛm ara. Mma w’ani ngu eyi so. Saa sɛnkyerɛnne ahorow yi betumi ayɛ PML ho sɛnkyerɛnne anaasɛ ɛnyɛ saa. Nanso eye sɛ wobɛsɔ wo ahwɛ.

Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ aduru biara no, Natalizumab betumi de nsunsuanso bɔne bi aba. Ɛnyɛ obiara na onya bi, nanso eye sɛ wobɛma w’ani ada hɔ.

Nneɛma bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo anaa akwahosan ho ɔbenfo amanneɛ ntɛm ara:

• Nneɛma a ɛma obi ho yɛ no hyew: Nsɛnkyerɛnne te sɛ honam ani akisikuru, ɛyaw, akisikuru, anim, anofafa, ne tɛkrɛma a ɛho ahonhon.
• Ɔhome a ɛyɛ den.
• Nsakrae a ɛba wɔ anisoadehu mu.
• Koko mu yaw.
• Adwene a ɛyɛ basaa, dadwen.
• Adwene a ɛyɛ basaa, te sɛ nea w’ani reyera.
• Adwene a ɛyɛ basaa.
• Sɛ wote nka sɛ woatɔ piti; a ne ti yɛ hare; ahwe ase.
• Nkate a ɛyɛ yare wɔ ɔkwan a ɛkɔ akyiri so anaasɛ sɛnkyerɛnne ahorow a ɛte sɛ atiridiinini.
• Nkae a wɔhwere.
• Mmea a wonnya wɔn brayɛ bere a ɛsɛ sɛ wɔwo (Missed menstrual periods).
• Ntini mu mmerɛwyɛ.
• Ɔhaw ahorow a ɛfa kari pɛ, kasa, anaa nantew ho. (Eyinom nso betumi ayɛ PML ho sɛnkyerɛnne, enti hwɛ yiye titiriw!)
• Nsɛnkyerɛnne ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ mmerɛbo apira: Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum; te nka sɛ ne ho nyɛ no den, atiridiinini; nsu a ɛyɛ mmerɛw; aduan ho akɔnnɔ a ɛyera; abofono; ɛyaw a ɛba yafunu no fã a ɛwɔ soro nifa so; ɔbrɛ anaa mmerɛwyɛ a ɛyɛ soronko; aniwa anaa honam ani a ɛyɛ kɔkɔɔ.
• Adwene a ɛne sɛ obekum ne ho, adwene a ɛsakra.
• Akuru anaa mogya a ɛtɔ a ɛnyɛ ne kwan so.
• Ɔyɛ mmerɛw anaasɛ wabrɛ wɔ ɔkwan soronko so.

Nneɛma bɔne a mpɛn pii no enhia sɛ wonya aduruyɛ mu afotu (nanso sɛ ɛkɔ so anaasɛ ɛhaw adwene a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo ):

• Tipaeɛ
• Nkwaa mu yaw
• Ntini mu akisikuru
• Ntini mu yaw
• Akisikuru, ɔfe
• Ɛyaw, kɔkɔɔ, anaa abufuw wɔ beae a wɔde aduru no guu no
• Ɔbrɛ

Ebia nneɛma bɔne a efi mu ba nyinaa nka saa nsɛm a wɔahyehyɛ yi ho. Sɛ wuhu biribi a ɛyɛ soronko ka eyinom ho a, bisa wo duruyɛfo.

Ɛhe na wode aduru yi sie?

Wɔremma wo kwan mma womfa saa aduru yi nkɔ fie. Ɛwɔ hɔ na wɔde ma wo wɔ ayaresabea anaa ayaresabea. Enti, ɛho nhia sɛ wohaw wo ho wɔ sɛnea wode besie no ho.

Nea etwa to no, nneɛma a ɛsɛ sɛ wokae (Take-Home Message) .

Okay, enti yɛaka Natalizumab ho asɛm pii. Sɛ wowɔ nsɛmmisa foforo bi fa saa aduru yi ho a, nsuro sɛ wubebisa wo duruyɛfo, ɔyarehwɛfo, anaa nnuruyɛfo. Wɔbɛboa wo.

Nea ɛho hia sen biara ne sɛ wobɛfa ayaresa no sɛnea wo duruyɛfo ka kyerɛ wo no pɛpɛɛpɛ, wɔ bere a ɛfata mu, ne ɔkwan pa so. Hu nneɛma bɔne a efi mu ba, titiriw tebea bi a wɔfrɛ no PML ho sɛnkyerɛnne. Sɛ wuhu biribi a ɛyɛ soronko a, ka kyerɛ wo duruyɛfo ntɛm ara.

Saa aduru yi betumi aboa wo ma woadi wo tebea no so. Enti, kɔ so yɛ den na kɔka oduruyɛfo no ho wɔ akwantu yi mu. Yɛpɛ sɛ wo ho tɔ wo ntɛm!

` Natalizumab, Multiple Sclerosis, Crohn yare, PML, Nnuru a ɛde ba, Nnuru a ɛko tia nyarewa, Tysabri