So mogya a ɛbɛtɔ no haw wo? Momma yɛnka Protein C Deficiency ho asɛm

So woate nka pɛn sɛ worebɛbɔ wo mogya? Anaasɛ mpofirim ara woate nka sɛ wo nan ho ahonhon na ɛyɛ wo yaw? Ebia nea enti a saa nneɛma yi ba no yɛ soronko wɔ nea wususuw ho. Ɛnnɛ yɛreka tebea bi a ɛntaa nsi nanso ɛho hia yiye a ɛsɛ sɛ yɛma yɛn ani da hɔ ho asɛm. Ɛno ne Protein C a Wonnya . Ɛwom sɛ ebia edin no te sɛ nea ɛyɛ nwonwa de, nanso ɛne sɛnea mogya tu wɔ yɛn nipadua mu no wɔ abusuabɔ. Ma yɛnhwɛ nea ɛyɛ, nea enti a ɛba, ne nea wubetumi ayɛ wɔ ho.

Dɛn ankasa ne Protein C a Wonnya?

Sɛ yɛbɛka no tiawa a, Protein C a enni hɔ no yɛ tebea a ɛma yɛn mogya tu sen sɛnea ehia, anaasɛ wɔ ɔkwan a ɛnteɛ so. Nkyerɛkyerɛmu tiawa bi ni.

Fa no sɛ wowɔ kuru bi wɔ wo nipadua so baabi. Afei, sɛnea ɛbɛyɛ na mogya no agyae no, ɛsɛ sɛ mogya bi tu. Ɛno yɛ ade a ɛfata. Ɛyɛ yɛn nipadua no ahobammɔ afiri. Nanso sɛ mogya a ɛtwetwe yi yɛ nea wontumi nni so na ɛtra so a, dɛn na ɛba? Ɛhɔ na ɔhaw no fi ase.

Abɔde mu nneɛma pii wɔ yɛn mogya mu a ɛhwɛ mogya a ɛtwetwe yi so, te sɛ kar breki nhyehyɛe. Protein C yɛ protein a ɛte saa no mu biako, protein a ɛho hia yiye a ɛhwɛ mogya a ɛtwetwe so. Wɔfrɛ eyi abɔde mu ‘ade a ɛko tia mogya a ɛtwetwe’ anaasɛ aduru a ekum mogya a ɛtwetwe . Ɛne sɛ, ade bi a ɛmma mogya ntumi nkɔ.

Afei deɛ wote aseɛ, ɛnte saa? Protein C Deficiency kyerɛ sɛ wunni saa protein yi a ɛdɔɔso wɔ wo mogya mu. Sɛ ɛba saa a, breki a ɛhwɛ ma mogya tu no ntumi nyɛ adwuma yiye. Nea efi mu ba ne sɛ mogya a ɛtwetwe fi ase hyehyɛ mogya ntini no mu. Mogya a ɛtwetwe a ɛba saa kwan yi so no betumi de tebea horow a asiane wom kɛse aba, na ɛde nkwa mpo to asiane mu. Sɛ nhwɛso no, mogya a ɛtɔ gu nan no mu ntini a emu dɔ no mu (Deep Vein Thrombosis) na tebea horow te sɛ saa mogya a ɛtɔ no mu paapae na ɛkɔhyɛ ahurututu no mu (Pulmonary Embolism) .

Saa tebea yi abu so dɛn?

Nokwarem no, eyi nyɛ biribi a abu so kɛse, nanso ɛntaa nsi sɛnea yesusuw no.

• Ɔkwan a ɛnyɛ den: Wobu akontaa sɛ eyi betumi aka nnipa 200 kosi 500 biara mu biako pɛ wɔ nnipa dodow no ara mu.
• Ɔkwan a emu yɛ den: Eyi ne ɔkwan a ɛntaa nsi. Ɛka nnipa bɛyɛ 500,000 kosi 750,000 biara mu biako. Nanso, ebia dodow ankasa no bɛboro saa akontaabu ahorow yi so koraa.

Saa tebea yi ka mmarima ne mmea nyinaa pɛpɛɛpɛ.

Dɛn ne eyi ho sɛnkyerɛnne?

Ɛsono yare yi ho sɛnkyerɛnne ahorow a egyina sɛ ɛyɛ mmerɛw anaasɛ emu yɛ den so. Momma yɛnhwɛ pon a ɛwɔ ase ha no na yɛnte eyi ase yiye.

Dɛn ne nneɛma a ɛde Protein C a enni hɔ ba?

Ade titiriw nti a tebea yi ba ne awosu mu nkɛntɛnso, a ɛkyerɛ sɛ ɛyɛ biribi a wɔde fi awo ntoatoaso so kɔ awo ntoatoaso so.

Nneɛma a Wɔde Ba a Wonya Fi Awo Mu

Awosu mu abɔde bi wɔ yɛn nipadua mu a ɛkyerɛ yɛn sɛ yɛnyɛ protein bi a wɔfrɛ no Protein C. Wɔfrɛ no PROC awosu mu abɔde . Sɛ nkwaadɔm mu nsakrae bi ba saa awosu mu nkwaadɔm yi mu a, ebia wɔannyɛ Protein C no yiye, anaasɛ sɛ wɔyɛ mpo a, ebia ɛrenyɛ adwuma yiye.

• Type I Deficiency: Eyi fi Protein C dodow a ɛso tew.
• Type II Deficiency: Eyi ba bere a Protein C dodow yɛ nea ɛfata, nanso protein no ntumi nyɛ adwuma yiye no.

Fa no sɛ awofo no mu biako wɔ PROC awosu mu abɔde a wɔayɛ no foforo yi. Afei 50% wɔ hɔ sɛ abofra a wɔwɔ no benya saa awosu mu abɔde a wɔayɛ no foforo no. Sɛ ɛba saa a, abofra no benya yare yi bi a emu nyɛ den.

Afei fa no sɛ awofo baanu no nyinaa wɔ saa awosu mu nkwaadɔm a wɔasakra no yi. Afei hokwan 25% wɔ hɔ sɛ abofra benya saa awosu mu nkwaadɔm abien a wɔayɛ no foforo no nyinaa. Saa abofra no benya tebea a emu yɛ den a ɛda sɛnkyerɛnne ahorow adi bere a wɔawo no no.

Nneɛma a Wɔde Ba a Wɔanya

Ɛnyɛ bere nyinaa na eyi fi awosu mu. Ayaresa mu tebea horow bi anaa nneɛma afoforo a ɛde ba nso betumi ama Protein C a ɛba fam.

• Vitamin K a enni nipadua mu
• Mogya a ɛma mogya tu a wɔfrɛ no Warfarin a wode bedi dwuma (yɛbɛka eyi ho asɛm akyiri yi) .
• mmerɛbo mu yare a emu yɛ den
• Tebea bi a wɔfrɛ no Disseminated Intravascular Coagulation (DIC) .
• Mmoawa a ɛyɛ hu (Sepsis) .

Ɔkwan bɛn so na wobetumi ahu yare yi?

Sɛ wo duruyɛfo susuw sɛ wowɔ saa yare yi a, wɔbɛsɔ nneɛma pii ahwɛ de akyerɛ sɛ ɛyɛ nokware.

• W’ankasa w’ayaresa ho abakɔsɛm: Sɛ́ ebia woanya mogya a ɛtwetwe ho haw pɛn.
• W’abusua aduruyɛ ho abakɔsɛm: So obi wɔ w’abusua mu a ɔwɔ mogya a ɛtwetwe ho haw ahorow yi?
• Mogya mu nhwehwɛmu: Eyi ne nea ɛho hia sen biara. Wɔsusuw wo Protein C dwumadi ne Protein C dodow a ɛwɔ wo mogya mu.
• Awosu mu nhwehwɛmu: Wobetumi ayɛ awosu mu nhwehwɛmu de ahwɛ sɛ ebia nsakrae bi aba PROC awosu mu nkwaadɔm no mu anaa. Nanso, eyi ho nhia na ama wɔatumi asi yare no so dua.

Ɔkwan bɛn so na wɔsa?

Ayaresa no gyina Protein C Deficiency ko a wowɔ ne sɛnea wo sɛnkyerɛnne ahorow no mu yɛ den so.

Ayaresa a wɔde ma wɔ ɔkwan a ɛnyɛ den so

• Nnipa dodow no ara nhia ayaresa: Nnipa dodow no ara nhia ayaresa biara. Nanso, ebia ɛho behia sɛ wɔde adwene titiriw na ebia wɔde sa yare bere a wɔreyɛ oprehyɛn, bere a wɔyem, sɛ wonya akwanhyia kɛse (sɛ nhwɛso no, kar akwanhyia), anaasɛ bere a wɔnyɛ apɔw-mu-teɛteɛ (sɛ nhwɛso no, sɛ wɔda mpa so a).
• Nnuru a ɛko tia mogya a ɛtwetwe: Sɛ woanya thrombotic event dedaw a, wo duruyɛfo bɛkyerɛw wo nnuru a ekum mogya a ɛtwetwe mogya.

Ayaresa a wɔde ma wɔ ɔkwan a emu yɛ den so

Wɔ tebea a emu yɛ den yi a ɛwɔ mmofra a wɔawo wɔn foforo mu no ho no, wɔde ayaresa titiriw bi a wɔfrɛ no Protein C concentrate (Ceprotin®) anaa mogya a wɔahyɛ no nwini a wɔayɛ no foforo ma.

Nsɛnnennen bɛn na eyi betumi de aba?

Nsɛnnennen atitiriw pii wɔ hɔ a ebetumi afi tebea yi mu aba.

• Honam ani haw a ɛfa warfarin ho: Sɛ wofi warfarin ase wie a, nnipa binom betumi anya akuru a ɛyɛ yaw, kɔkɔɔ anaa kɔkɔɔ. Eyinom taa ba nipadua no atifi, nsa anaa anan so. Sɛ wɔansa eyi yiye a, ebetumi ama honam ani ntini ne ntini a ɛwɔ ase no awu.
• Pulmonary Embolism: Mogya a ɛyɛ mmerɛw a ɛba anan mu (deep vein thrombus) betumi abubu, afa mogya no mu, na akɔtra ntini bi mu wɔ ahurututu no mu. Eyi yɛ tebea a ɛde nkwa to asiane mu.
• Purpura Fulminans: Mogya a ɛtwetwe wɔ abofra a wɔawo no foforo nipadua nyinaa mu. Sɛ wɔansa a, ebetumi akum obi.
• Nsɛnnennen a ɛwɔ plasma ayaresa foforo mu: Sɛ wɔkɔ so ma nkokoaa saa ayaresa yi a, nsɛnnennen betumi aba esiane nsu a ɛkɔ soro wɔ nipadua no mu (nsu a ɛboro so) nti.

Dɛn na wubetumi ahwɛ kwan bere a wɔahu sɛ woanya yare no akyi?

Nea efi eyi mu ba no gu ahorow kɛse a egyina sɛnea yare no mu yɛ den so.

Nkokoaa a wɔwɔ Protein C Deficiency a emu yɛ den ho nkɔmhyɛ no nyɛ papa. Ebia wowuwu mpo wɔ awo akyi bere tiaa bi. Nsɛm a ɛdɔɔso nni hɔ a wɔde bɛka nea wɔn a wɔwɔ tebea a emu yɛ den yi nkwa nna tenten yɛ.

Sɛ wowɔ ɔyare a emu nyɛ den a, wowɔ asiane mu sɛ ntini mu thromboembolism bɛsan aba bio. Asiane nso wɔ hɔ sɛ mogya a ɛtwetwe no bɛkɔ ahurututu no mu. Sɛ wopɛ sɛ wunya nea eye sen biara a, ɛho hia sɛ wokɔ so yɛ bere a wo duruyɛfo no di akyi no. Eyi bɛma watumi ahwɛ wo tebea no yiye na wayɛ nsakrae wɔ w’ayaresa mu sɛnea ɛho hia.

So wobetumi asiw eyi ano?

Esiane sɛ Protein C a enni hɔ no fi awosu mu kɛse nti, wontumi nsiw ano. Nanso, awofo ne mmofra betumi akɔ mogya ho ɔbenfo nkyɛn na wɔasua ho nsɛm pii na wɔayɛ nhwehwɛmu a ɛho hia.

Afei nso, ɛtɔ mmere bi a wobetumi asiw Protein C a enni hɔ a aduruyɛ mu tebea afoforo de ba no ano. Nhwɛsoɔ,

• Estrogen hormone a ɛwɔ awo ano aduru bi a mmea nom mu no betumi ama asiane a ɛwɔ hɔ sɛ mogya bɛtɔ no ayɛ kɛse.
• Nneɛma te sɛ sigaretnom, kɛseyɛ mmoroso, nyinsɛn, ne apɔw-mu-teɛteɛ a wɔnyɛ no ma asiane yi kɔ soro bio.

Wɔ tebea horow bi mu no, wo duruyɛfo betumi akyerɛw nnuru a ekum mogya a ɛtwetwe mogya no dodow a wɔde siw ano na ama asiane yi so atew. Enti, ɛho hia yiye sɛ wo ne wo duruyɛfo bɛkasa pefee wɔ nneɛma a ɛde asiane ba wo ho no ho.