So wo ba no wɔ saa sɛnkyerɛnne ahorow yi? Momma yɛnhwɛ Reye Syndrome no yiye!

So woahyɛ no nsow pɛn sɛ wo ba kumaa no nya atiridii anaa atiridiinini, na afei mpofirim ara ne suban sesa, ɔfe mpɛn pii, anaasɛ ɔda kɛse? Sɛ wuhu nsakrae a ɛte saa a, mmu w’ani ngu so sɛ ɛyɛ daa. Efisɛ, ebetumi ayɛ tebea bi a ɛntaa nsi nanso ebetumi ayɛ asiane a wɔfrɛ no "Reye's Syndrome" ho sɛnkyerɛnne. Momma yɛnka eyi ho asɛm nnɛ.

Dɛn ne Reye Yare no?

Sɛ yɛbɛka no tiawa a, Reye’s Syndrome yɛ tebea a ɛntaa nsi nanso ebetumi ayɛ nea emu yɛ den. Ɛba bere a abofra amemene ahonhon na ne mmerɛbo dwumadi gyae mpofirim bere a ɔyare mmoawa a wɔde ɔyare mmoawa ba, mpɛn pii no, atiridiinini, atiridiinini, anaa akisikuru akyi no. Wɔtaa hu saa tebea yi bere a wɔma mmofra aspirin de adi ɔyare mmoawa ho sɛnkyerɛnne ahorow so no. Saa sɛnkyerɛnne ahorow yi betumi ada adi wɔ dapɛn biako mu wɔ bere a ɔyare mmoawa no afi ase no.

Hena na ɛda adi kɛse sɛ obenya Reye Yare no?

Wobu eyi titiriw sɛ mmofraberem yare. Nanso, ebetumi aba wɔ mfe biara a obi adi mu. Nanso, wɔtaa hu wɔ mmofra a wonnii mfe 18. Wɔbɔ saa tebea yi ho amanneɛ titiriw wɔ osutɔbere ne awɔw bere mu (wɔ yɛn man yi mu no, osutɔ bere mu, bere a nyarewa a mmoawa de ba abu so no).

Tebea yi abu so dɛn?

Nokwarem no, mprempren Reye Yare no yɛ tebea a ɛntaa nsi koraa. Sɛ nhwɛso no, wɔ United States no, nnipa baanu pɛ na wɔbɔ amanneɛ sɛ wɔanya saa yare yi afe biara.

Nea enti titiriw a ɛte saa ne sɛ mprempren nkurɔfo nim yare yi yiye. Titiriw no, awofo pii nim sɛ ɛnyɛ papa sɛ wɔde aspirin bɛma abofra de asa yare no ho sɛnkyerɛnne bere a wanya atiridiinini no. Afei nso, nnuru a wɔde ko tia nyarewa a mmoawa de ba te sɛ influensa ne akisikuru no ama yare yi a abu so no so atew.

Ɔkwan bɛn so na Reye’s Syndrome ka abofra nipadua?

Sɛ wo ba nya ɔyare mmoawa te sɛ atiridiinini anaa akisikuru akyi a, ebetumi afi ase anya sɛnkyerɛnne foforo wɔ nna kakraa bi mu (ebia dapɛn biako). Ade a ɛho hia sen biara a ɛsɛ sɛ wokae ne sɛ woremma wo ba no aspirin da wɔ ne sɛnkyerɛnne ahorow ho a wunnyaa aduruyɛfo afotu. Saa a wobɛyɛ no betumi ama asiane a ɛwɔ hɔ sɛ wubenya Reye’s Syndrome no ayɛ kɛse.

Reye Syndrome ma nhyɛso a ɛwɔ abofra amemene mu no kɔ soro mpofirim, na ebetumi ama nsakrae aba mpofirim wɔ suban ne ne nipasu mu. Fa no sɛ wo ba a odi agoru na n’ani gye no ahwere agode a n’ani gye ho no ho anigye mpofirim, anaasɛ ne bo befuw ntɛm na ne ho adwiriw no wɔ nneɛma a ɛte sɛ nea ɛho nhia ho. Saa nsakrae a ɛba wɔ adwene mu yi betumi ayɛ Reye’s Syndrome ho sɛnkyerɛnne a edi kan. Sɛ wuhu saa sɛnkyerɛnne ahorow yi ntɛm a, wubetumi afi ase sa yare no ntɛm na aboa wo ba no ma ne ho atɔ no.

Dɛn ne Reye Yare no ho sɛnkyerɛnne?

Nsɛnkyerɛnne no tumi gu ahorow wɔ onipa biara mu, na ɛsono sɛnea yare no mu yɛ den nso. Nsɛnkyerɛnne a edi kan ne nea ɛkyerɛ sɛ obi anya ɔyare mmoawa a ɛtaa ba. Ɛne sɛ, atiridiinini, menewam yaw, atiridiinini, anaa akisikuru. Bere a wɔanya ɔyare mmoawa yi ho sɛnkyerɛnne bɛyɛ nnanu kosi ason akyi no, sɛnkyerɛnne ahorow a ɛfa Reye Yare no ho no fi ase da adi. Wɔne:

• Ɔfe a wɔtaa fa.
• Ɔbrɛ ne nna a ɛtra so a wɔte nka .
• Nneɛma te sɛ dadwen, nkae a wontumi nkae, adwene a ɛyɛ basaa, ne nsusuwii hunu .
• Suban mu nsakrae: atirimɔdensɛm, abufuw ntɛmntɛm, ntɔkwaw.
• Ahome a wɔhome ntɛmntɛm.

Saa nsakrae yi ba amemene no dwumadi mu esiane nhyɛso a ɛkɔ soro wɔ ti nhwi no mu (`(Intracranial pressure)`). Bere koro no ara mu no, mmerɛbo no dwumadi nso sɛe. Sɛ yare no mu yɛ den kɛse a, wubetumi ahu sɛnkyerɛnne ahorow te sɛ:

• Akisikuru a ɛma obi ho kyere no.
• Coma yɛ tebea a ɛma obi ntumi nhu hwee, te sɛ nea obi da kɛse.
• Nhumu a ɛyera koraa.
• Mogya a ɛtwetwe mogya ho haw ahorow.
• Ammonia dodow a ɛkɔ soro wɔ mogya no mu.

Nea ɛho hia: Sɛ wo ba da saa sɛnkyerɛnne ahorow yi mu biako anaa nea ɛboro saa adi, sɛ́ ɛyɛ bere a ɔyare mmoawa atiridiinini anaasɛ atiridii no ano abrɛ ase nna kakraa bi akyi a, ɛsɛ sɛ wohwehwɛ aduruyɛfo afotu ntɛm ara, efisɛ eyinom betumi de ne nkwa ato asiane mu.

Dɛn na ɛde Reye Yare no ba?

Nokwarem no, wonnya nhuu nea ɛde Reye Yare no ba ankasa.

Nanso, mpɛn pii no, aspirin anaa salicylates a wɔde ma abofra a ɔwɔ ɔyare mmoawa (te sɛ atiridii anaa akisikuru) de siw yare no ho sɛnkyerɛnne ahorow ano no na ɛde tebea yi ba. Nyarewa bi a efi mmoawa mu a ebetumi de Reye’s Syndrome aba no bi ne:

• Papu
• Akokɔsrade
• Ɔhome mu ɔyare mmoawa
• Atiridiinini a ɛtaa ba

Reye’s Syndrome ho sɛnkyerɛnne no fi nsu a ɛboaboa ano anaasɛ nhyɛso a ɛkɔ soro wɔ amemene no mu ntini mu (amemene mu ntini a ɛyɛ mmerɛw) ne nsakrae a ɛba mmerɛbo no mu.

Nhwehwɛmu ahorow bi kyerɛ sɛ saa tebea yi ba mmerɛbo mu esiane sɛnea mitochondria (`(Mitochondria)`) a ɛwɔ nkwammoaa no mu no sɛe nti. Sɛ yɛbɛka no tiawa a, mitochondria (`(Mitochondria)`) yɛ anyinam ahoɔden mfiri nketewa a ɛma yɛn nkwammoaa ahoɔden. Sɛ eyinom sɛe a, mmerɛbo no ntumi nyɛ adwuma yiye na yare no ho sɛnkyerɛnne da adi. Nanso, wonnya nhuu nea enti a saa mitochondria (`(Mitochondria)`) yi sɛe.

So Aspirin De Reye Yare no Ba?

Nhwehwɛmu ahorow ada no adi sɛ aspirin anaa ade bi a wɔfrɛ no salicylate betumi akanyan Reye’s Syndrome na ama sɛnkyerɛnne ahorow no mu ayɛ den. Nanso, sɛnea yɛadi kan aka no, nea ɛde ba ankasa da so ara yɛ ahintasɛm. Enti, hwɛ hu sɛ wo ne oduruyɛfo bɛkasa ansa na wode aspirin ama wo ba bere a ɔwɔ ɔyare mmoawa te sɛ atiridiinini no. Kenkan aduru biara a wode bɛma abofra no din yiye, na hwɛ hu sɛ ɛfata mfe a wadi ne sɛnea wɔde bɛma no. Bisa wo duruyɛfo sɛ wowɔ nsɛmmisa bi a.

Sɛnea Reye Yare no Yɛ Adwuma Wɔ Nipadua no Mu (Pathophysiology) .

Wɔda so ara nte sɛnea yare yi yɛ adwuma wɔ abofra nipadua mu no ho nsɛm nyinaa (`(Pathophysiology)`) ase yiye.

Nanso, nhwehwɛmu ahorow kyerɛ sɛ saa tebea yi ba bere a mitochondria (`(Mitochondria)`) nkwammoaa a asɛe no ne ɔyare mmoawa bi ka bom no. Sɛ aspirin hyɛn abofra no nipadua mu saa bere yi a, ɔsɛe a ɛba mitochondria (`(Mitochondria)`) no kɔ soro na yare no ho sɛnkyerɛnne no mu yɛ den. Esiane mitochondria (`(Mitochondria)`) a asɛe nti, ammonia dodow a ɛwɔ mogya no mu no kɔ soro. Afei amemene no fi ase hohoro (`(Cerebral edema ne intracranial pressure)`). Sɛ nhyɛso a ɛba amemene no so no kɔ soro dodo a, srade a ɛwɔ asaabo no mu no fi ase sɛe (`(Fatty degeneration)`), na ntini mu nkwammoaa (`(Neurons)`) dwumadi nso so tew.

Ɔkwan bɛn so na wohu sɛ obi anya Reye Syndrome? (Nyare a Wɔahu) .

Nnuruyɛfo betumi asusuw sɛ ɔwɔ Reye’s Syndrome sɛ abofra bi wɔ ɔyare mmoawa bi na afei ɔda sɛnkyerɛnne ahorow a ɛne Reye’s Syndrome hyia adi, te sɛ ɔfe ne suban mu nsakrae (te sɛ basabasayɛ, adwene a ɛyɛ basaa). Afei wɔbɛyɛ nhwehwɛmu ahorow de ayi tebea afoforo a ebetumi de sɛnkyerɛnne a ɛte saa ara aba no afi hɔ.

Sɛ wohu sɛ wo ba no anya Reye’s Syndrome a, wɔbɛkyekyɛ no mu afã horow a egyina sɛnea emu yɛ den so. Wɔde Roma akontaahyɛde ahorow a efi I (baako - a emu nyɛ den koraa) kosi V (anum - a emu yɛ den sen biara) ahyɛ saa mmere yi agyirae.

Nhwehwɛmu bɛn na wɔde hu yare no?

Ebia oduruyɛfo no bɛyɛ nhwehwɛmu ahorow pii de akyerɛ sɛ wɔahu yare no. Eyinom bi ne:

• Mogya mu nhwehwɛmu: Hwɛ sɛnea ammonia dodow wɔ mogya no mu na hwɛ sɛ awuduru bi wɔ nsu mu anaa.
• Mfoniniyɛ mu nhwehwɛmu: MRI anaa CT scan a wɔyɛ wɔ amemene no mu.
• Berɛbo mu nipadua mu nhwehwɛmu: Bere a wɔfa mmerɛbo no fã ketewaa bi de yɛ nhwehwɛmu.
• Spinal tap: Nsu a atwa amemene ne akyi berɛmo (cerebrospinal fluid) ho ahyia no mu nhwehwɛmu.

So wobetumi ahu Reye Syndrome no wɔ ɔkwan a ɛnteɛ so?

Esiane sɛ Reye Yare no ho sɛnkyerɛnne te sɛ tebea afoforo pii de nti, ɛtɔ mmere bi a wobetumi ahu no yiye. Nanso, eyi nyɛ ade a ɛntaa nsi. Tebea horow a wobetumi ahu wɔ ɔkwan a ɛnteɛ so no bi ne:

• Encephalitis (amemene mu atiridii) .
• Meningitis (`(Adwene mu yare)`) .
• Asikreyare (`(Asikreyare)`) .
• Nnuru a wɔde di dwuma boro so
• Awuduru (`(Awuduru)`) .
• Nkokoaa a wowuwu mpofirim (`(Nkokoaa a wowuwu mpofirim)`)
• Adwene mu yare

Ɔkwan bɛn so na wɔsa Reye Yare no?

Botae titiriw a ɛwɔ ayaresa mu ne sɛ ɛbɛbɔ abofra no amemene ho ban. Eyi kyerɛ sɛ wɔbɛtew amemene no mu ahonhon so, asiesie nneɛma a asɛe wɔ mmerɛbo ne nipadua mu nneɛma a ɛsakra no so (`(Metabolic injury)`), na asiw ahurututu mu nsɛnnennen ano. Ayaresa no betumi ayɛ nea edidi so yi:

• Sɛnea ɛbɛyɛ a ɛbɛyɛ mmerɛw sɛ wobɛhome no, fa afiri bi hyɛ mframa afiri no mu (endotracheal intubation) anaasɛ fa bata mframa afiri ho.
• Akokoaa no ti a wɔbɛma akɔ soro.
• Nnuru a wɔde ma de tew ammonia dodow a ɛwɔ mogya mu (`(Ammonia detoxicants)`).
• Nnuru a wɔde ma de siw asikre a ɛwɔ mogya mu (`(Glucose)`) ano.
• Ma vitamin K anaa plasma na ama mogya a ɛbɛtɔ no atu mpɔn.

Sɛ wohu sɛ wo ba no anya Reye’s Syndrome a, wɔde no bɛkɔ Intensive Care Unit (ICU) ntɛm ara na wɔafi ase ayɛ ayaresa. Aduruyɛfo kuw no bɛhwɛ biribiara so bere nyinaa, a abofra no nipadua mu hyew ne akwaa a ɛho hia no dwumadi ka ho, de ahwɛ sɛ ebia ayaresa no di yiye anaa.

So ayaresa no mu nsunsuanso bɔne bi wɔ hɔ?

Mmofra dodow no ara a wɔahu sɛ wɔwɔ Reye Syndrome no ho tɔ wɔn koraa. Nanso, sɛ abofra no amemene mu ahonhon no mu yɛ den yiye a, nneɛma bɔne bi betumi aba. Eyinom bi ne:

• Memory loss (`(Nkae a ɛyera)`) .
• Adesua mu nsɛnnennen (`(Asuade a ɛyɛ den)`) .
• Anisoadehu ne aso a ɛyera
• Ɔhaw a ɛfa ɔkasa ne kasa ho
• Ɛyɛ den sɛ wobɛkanyan nipadua no na woayɛ da biara da nnwuma te sɛ ntadehyɛ.

Wɔ nsɛm a ɛte sɛɛ mu no, abofra no hia mmoa ne ɔhwɛ soronko bere a ɔrenyin no.

Abofra no ho bɛtɔ no ntɛm dɛn wɔ ayaresa akyi?

Sɛ wɔsa wo ba no yare wie a, sɛ wo ba no amemene mu ahonhon no ano brɛɛ ase a, ne ho bɛtɔ no. Ebia ebegye nna kakraa bi kosi adapɛn kakraa bi ansa na wo ba no ho atɔ no sɛnea ɛbɛyɛ a obefi ayaresabea. Aduruyɛ kuw no bɛma woahu wo ba no nkɔso.

Sɛ me ba no wɔ Reye’s Syndrome a, dɛn na metumi ahwɛ kwan?

Sɛnea wɔkyerɛ abofra yare no gyina sɛnea wɔahu sɛ ɔyare no mu yɛ den no so, titiriw baabi a amemene no ahonhon kodu ne sɛnea ammonia dodow a ɛwɔ mogya no mu no te. Sɛ yare no kɔ so ntɛmntɛm na abofra no kɔ koma mu a, hokwan a ɛwɔ hɔ sɛ ne ho bɛtɔ no no sua. Nanso, sɛ wohu yare no na wɔsa no ntɛm a, hokwan a ɛwɔ hɔ sɛ wɔn ho bɛtɔ no no dɔɔso yiye.

Mmofra a wɔahu sɛ wɔwɔ Reye’s Syndrome no dodow bɛyɛ 21%. Eyi fi mmofra a wɔwɔ yare no fã I (a emu nyɛ den) no mu nea ennu 2% kosi mmofra a wɔwɔ yare no fã V (coma) no mu 80%. Sɛ wohu no ntɛm na wɔsa no yare a, ɛma hokwan a ɛwɔ hɔ sɛ obenya nkwa no yɛ kɛse.

Mmofra a wohu Reye Yare no ho sɛnkyerɛnne a emu yɛ den no betumi anya nkɛntɛnso bɔne a ɛbɛtra hɔ akosi wɔn mpanyin afe so. Sɛ nhwɛso no, amemene a ɛsɛe, adwene mu nkɔso ho haw, akisikuru, ntini a ɛyɛ mmerɛw, ne ntini mu haw.

So aduru pɔtee bi wɔ hɔ a wɔde sa Reye Yare no?

Aduru pɔtee biara nni hɔ a wɔde bɛsa eyi. Nanso, mmofra dodow no ara ho tɔ wɔn koraa, a egyina sɛnea wɔahu yare no so. Ayaresa no botae ne sɛ ɛbɛtew sɛnkyerɛnne ahorow so na asiw nsɛnnennen a ɛtra hɔ kyɛ anaa owu ano.

Ɔkwan bɛn so na wobetumi asiw Reye Syndrome ano?

Eyi ne ade a ɛho hia sen biara a ɛsɛ sɛ yɛn nyinaa hu. Esiane sɛ abusuabɔ bi da aspirin ne Reye Syndrome ntam nti, wobetumi asiw yare yi ano denam aspirin a wɔbɛkwati sɛ wɔde bɛma mmofra, titiriw mmofra a wonnii mfe 16 no so. Sɛ wo ba hia aspirin de asa aduruyɛ mu tebea bi a, mma aspirin da a wo ne oduruyɛfo nkasa ho asɛm.

Bere nyinaa kenkan nea wɔakyerɛw so no yiye ansa na wode aduru biara ama abofra, hwɛ sɛnea aduru no mfe fata, na hwɛ sɛnea wɔde bɛma abofra no ho akwankyerɛ. Sɛ w’adwene mu yɛ wo naa a, bisa wo duruyɛfo anaa nnuruyɛfo.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Sɛ wo ba da Reye’s Syndrome ho sɛnkyerɛnne biara adi wɔ ɔyare mmoawa atiridii anaa ɔyare mmoawa akyi, anaasɛ woama wo ba no aspirin anaa aduru a salicylate wom a wunnyaa aduruyɛfo afotu a, kɔ oduruyɛfo nkyɛn ntɛm ara.

Bere bɛn na ɛsɛ sɛ mekɔ Emergency Department (ETU) ?

Sɛ wo ba no nya akisikuru (`(Seizures)`), a ɛkyerɛ sɛ n’adwene fi ne ho so bere tiaa bi, ɔwosow ne nsa ne ne nan a ontumi nni so, ɔyɛ basaa, anaasɛ ɔda adwene a ɛyɛ basaa adi a, frɛ 911 ntɛm ara, anaa fa wo ba no kɔ baabi a ɛbɛn no a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ mu. Mpɛn pii no, akisikuru no di fi sikɔne 30 kosi bɛyɛ simma abien.

Nsɛm bɛn na ɛsɛ sɛ mibisa me duruyɛfo?

• So me ba no da so ara wɔ Reye’s Syndrome ho sɛnkyerɛnne bere a wafi ayaresabea hɔ no?
• Sɛ wohu sɛ ɔwɔ Reye Syndrome a, ɛbɛka me ba no daakye dɛn?
• Nnuru bɛn na ɛnsɛ sɛ mema me ba bere a ɔyare no?

So Pepto-Bismol® dodow biako betumi ama Reye’s Syndrome aba?

Ade bi a wɔfrɛ no salicylate a ɛte sɛ aspirin nso wɔ Pepto-Bismol® mu. Enti, ɛnsɛ sɛ wɔde ma mmofra a wonnya aduruyɛ mu afotu. Aspirin a wɔde ma bere a ɔyare mmoawa te sɛ atiridiinini no betumi de Reye’s Syndrome ho sɛnkyerɛnne aba. Nanso, sɛnea yɛadi kan aka no, wonnya nhuu nea ɛde Reye Yare no ba ankasa. Kenkan aduru a wɔakyerɛw so bere nyinaa anaa bisa wo nnuruyɛfo anaa oduruyɛfo ansa na wode aduru biara ama abofra.

Awiei koraa no, nkrasɛm a ɛho hia sen biara

Sɛ wunim Reye Yare no ho sɛnkyerɛnne na wuhu nsakrae a ɛba wo ba no nneyɛe mu anaa sɛnkyerɛnne foforo wɔ ɔyare mmoawa bi akyi a, ɛbɛyɛ papa sɛ wobɛkɔ oduruyɛfo nkyɛn ntɛm ara sɛnea wubetumi. Ma wo ba no nhu wɔn nnuru a wɔde bɔ wɔn ho ban no. Eyi ho hia titiriw wɔ mmere a ɔyare mmoawa abu so (te sɛ osutɔ bere). Sɛ wohu sɛ wo ba no anya Reye’s Syndrome a, w’aduruyɛfo kuw no bɛma woahu wo ba no akwahosan tebea na wɔama wo mmoa a ɛho hia. Nea ehia paa ne sɛ wobɛma wo ho adwo wo na woayɛ w’ade nyansam.

` Reye yare, aspirin, mmofraberem nyarewa, atiridiinini a efi ɔyare mmoawa mu, mmerɛbo mu yare, amemene mu ahonhon, ɔfe