So ɛtɔ mmere bi a wote nka sɛ woabrɛ anaasɛ woayɛ mmerɛw wɔ ɔkwan soronko so a ntease biara nnim? So wo honam ani hwɛbea yɛ kɔkɔɔ? Anaasɛ wo ba a wɔawo no foforo no jaundice no nkɔ adapɛn abien akyi? Ebia nea ɛde saa nneɛma yi ba ne enzyme bi a wɔfrɛ no G6PD a enni wo nipadua mu. Mma ɛnhaw wo, eyi yɛ tebea a abu so yiye. Ɛnnɛ, yɛbɛka nea G6PD yɛ, nea ɛba bere a ɛba fam, ne G6PD sɔhwɛ no ho asɛm tiawa na emu da hɔ.
Dɛn ne G6PD kɛkɛ?
Susuw mogya mu nkwammoaa kɔkɔɔ a ɛwɔ yɛn nipadua mu no ho sɛ asraafo a wɔreyɛ adwuma. ‘Ɔwɛmfo’ bi wɔ hɔ a ɔbɔ saa asraafo yi ho ban fi nneɛma ahorow a epira ho. Saa ɔwɛmfo no yɛ enzyme bi a wɔfrɛ no G6PD.
Sɛ yɛbɛka no tiawa a, G6PD (Glucose-6-Phosphate Dehydrogenase) yɛ enzyme a ɛho hia yiye a ɛbɔ yɛn nkwammoaa ho ban, titiriw mogya mu nkwammoaa kɔkɔɔ a ɛwɔ yɛn mogya mu no fi nnuru a epira ho. Yɛn nipadua no yɛ nneɛma a epira (a wɔsan frɛ no ‘Free Radicals’ anaa ‘Reactive Oxygen Species’ ) a ɛba bere a yɛreyɛ adwuma sɛnea ɛsɛ. G6PD enzyme no yɛ eyi denam nneɛma a epira yi a esiw ano na ɛnsɛe nkwammoaa no so.
Dɛn na ɛba bere a G6PD sua no?
Afei susuw nea ɛbɛba sɛ saa ‘abobɔne’ (G6PD) no sua wɔ nipadua no mu ho hwɛ? Afei saa nneɛma a epira no ba na efi ase sɛe yɛn mogya mu nkwammoaa kɔkɔɔ no. Wɔfrɛ saa adeyɛ a ɛma mogya mu nkwammoaa kɔkɔɔ no sɛe ntɛmntɛm sen sɛnea wobetumi ayɛ yi hemolysis .
Sɛ wohwere mogya mu nkwammoaa kɔkɔɔ pii wɔ saa kwan yi so a, wo nipadua no nnya mframa pa a ehia no. Ɛno ne nea yɛfrɛ no mogya a ɛtɔ kɔ nipadua mu, anaasɛ sɛ yɛbɛka no yiye a, mogya a ɛtɔ kɔ mogya mu . Eyi nti na wote nka sɛ woabrɛ, woayɛ mmerɛw, na wo ho ayɛ wo hyew bere nyinaa no.
Ɔkwan bɛn so na G6PD a enni hɔ no ba?
G6PD a enni nipadua mu no yɛ awosu mu tebea a efi awosu mu . Eyi kyerɛ sɛ ɛyɛ biribi a wunya fi w’awofo hɔ. Sɛ nkwaadɔm mu nsakrae bi ba awosu mu nkwaadɔm a ɛkyerɛ wo sɛ yɛ G6PD enzyme no mu a, saa enzyme yi dodow a wɔyɛ wɔ nipadua no mu no so tew.
Nanso ade a ɛho hia wɔ ha ne sɛ ɛnyɛ obiara a G6PD nnim no na obenya yare no ho sɛnkyerɛnne. Nnipa pii tra ase sɛnea ɛsɛ a ɔhaw biara nni ho. Nanso, nneɛma bi a efi akyi (yɛfrɛ eyinom ‘nneɛma a ɛkanyan’) betumi ama sɛnkyerɛnne ahorow no ada adi mpofirim.
Nneɛma a ɛkanyan G6PD sɛnkyerɛnne ahorow
Saa nneɛma a ɛkanyan no yi ma nipadua no ma saa ‘free radicals’ a epira a yɛkaa ho asɛm no dodow kɔ soro mpofirim. Obi a G6PD nnim no ntumi nni nneɛma a epira a ɛrekɔ soro yi so. Ɛno na mogya mu nkwammoaa kɔkɔɔ no fi ase sɛe, na yare no ho sɛnkyerɛnne da adi.
| Trigger Type a Wɔde Yɛ Adwuma | Nkyerɛmu |
|---|---|
| Nnuan bi | Fava bankye titiriw. Wobetumi akanyan sɛnkyerɛnne ahorow denam wɔn a wobedi anaasɛ wɔn pollen a wɔhome mpo so. Wɔsan frɛ saa tebea yi sɛ ‘Favism’. |
| Nnuru bi | Nnuru bi a wɔde kum ɛyaw te sɛ Aspirin, Acetaminophen (Paracetamol), Sulfa nnuru bi, nnuru a ekum ɔyare mmoawa bi ne asramma nnuru ne nea ɛho hia titiriw. Nnom aduru biara a wunni aduruyɛ mu afotu. |
| Mmoawa ne mmoawa a wɔde nyarewa ba | Nyarewa biara, efi atiridiinini so kosi ɔyare mmoawa a emu yɛ den so, betumi akanyan G6PD sɛnkyerɛnne ahorow. |
G6PD a enni nipadua mu no taa yɛ mmarima sen mmea, na ɛtaa ba nnipa a wofi Afrika, Asia, ne Mediterranea abusua mu.
Hena na ɛsɛ sɛ ɔyɛ G6PD sɔhwɛ no?
Ebia wo duruyɛfo bɛkamfo akyerɛ sɛ wɔnyɛ G6PD nhwehwɛmu (mogya mu nhwehwɛmu a ɛnyɛ den), titiriw sɛ wowɔ sɛnkyerɛnne ahorow a edidi so yi mu biara a:
- Ɔbrɛ ne mmerɛwyɛ a wontumi nkyerɛkyerɛ mu
- Wora a ɛyɛ mmerɛw
- Ɛyɛ den sɛ wobɛhome anaasɛ wobɛhome
- Koma a ɛbɔ denneennen
- Wora ne aniwa a ɛyɛ kɔkɔɔ (jaundice) .
- Nsu a ɛyɛ tuntum (a kɔla yɛ cola) .
- Akyi anaa yafunu mu yaw
- Mprempren tebea a ɛyɛ basaa no
Hwɛ nkokoaa a wɔawo wɔn foforo no titiriw.
Ɛyɛ ade a ɛfata sɛ akokoaa a wɔawo no foforo benya jaundice. Nanso sɛ ɛtra hɔ bɛboro adapɛn abien , akokoaa no nsu dan tuntum, na nsu no dan fitaa a, ebia oduruyɛfo no besusuw sɛ G6PD nnim na wayɛ nhwehwɛmu yi.
Ɔkwan bɛn so na yɛbɛte sɔhwɛ amanneɛbɔ no ase?
G6PD nhwehwɛmu mu aba betumi ayɛ soronko kakra wɔ lab biara mu, enti wo duruyɛfo nkutoo na obetumi ama wo nsɛm a ɛyɛ nokware sen biara . Nanso, mpɛn pii no, nneɛma ahorow abiɛsa na efi mu ba.
- Normal: Wowɔ G6PD enzyme a ɛdɔɔso wɔ wo nipadua mu. Wonni G6PD a enni hɔ.
- Nneɛma a Ɛkɔ So a Ɛkɔ Akyiri: Enzyme dodow yɛ 10% kosi 60% wɔ nea ɛte daa no mu. Mpɛn pii no, saa nkurɔfo yi nya yare no ho sɛnkyerɛnne bere a wɔanya ɔyare mmoawa anaasɛ wɔnom nnuru bi a enye nkutoo.
- Deficiency a emu yɛ den: Enzyme no wɔ hɔ a ennu 10% wɔ dodow a ɛfata mu. Ebia saa nkurɔfo yi benya mogya a ɛtɔ kɔ nipadua no mu anaasɛ wɔtaa nya yare no ho sɛnkyerɛnne.
G6PD a enni nipadua mu no ayaresa ne ne di
G6PD a enni nipadua mu no nyɛ yare a wotumi sa koraa, efisɛ ɛyɛ awosu mu tebea. Nanso, sɛ wohwɛ so yiye a, wubetumi atra ase a ahoɔden wom a ɔhaw biara nni ho .
Ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wobɛkwati ‘nneɛma a ɛkanyan’ a ɛde sɛnkyerɛnne ahorow no ba no. Eyi ne ayaresa titiriw.
Ɛsɛ sɛ wo:
- Kwati sɛ wubedi fava bankye koraa.
- Kwati sɛ wobɛnom nnuru a wɔde kum ɛyaw te sɛ Aspirin ne Acetaminophen (Paracetamol) a wo duruyɛfo mpene so.
- Ka kyerɛ wo duruyɛfo sɛ wowɔ G6PD a enni wo mu ansa na woakyerɛw aduru biara ama wo .
- Sɛ wunya ɔyare mmoawa bi a, kɔ ayaresabea ntɛm ara.
Sɛ wo yare no ho sɛnkyerɛnne no nyɛ den a, ebia wo duruyɛfo bɛkyerɛw wo folic acid ne iron nnuru. Sɛ wo mogya a ɛtɔ wo mu no mu yɛ den a, ebia ebehia sɛ wɔde wo kɔ ayaresabea na wɔma wo mogya anaa oxygen ayaresa.
Ma ɛntra w’adwenem sɛ nnuru a ekum ɔyare mmoawa te sɛ Vitamin E remmoa tebea yi.
Nkrasɛm a Wɔde Kɔ Fie
- G6PD a enni nipadua mu no yɛ awosu mu tebea a abu so a wɔde ma awo ntoatoaso ahorow na ɛnyɛ biribiara a ɛsɛ sɛ wosuro.
- Nnipa pii nni yare no ho sɛnkyerɛnne biara koraa. Nsɛnkyerɛnne no da adi bere a wɔde wɔn ho hyɛ ‘nneɛma a ɛkanyan’ te sɛ fava bankye, nnuru bi, anaa ɔyare mmoawa mu no.
- Adwuma titiriw a wɔde di dwuma ne sɛ wɔbɛkwati saa nneɛma a ɛkanyan adwene yi.
- Sɛ wowɔ G6PD a, ɛho hia sɛ wobɔ oduruyɛfo biara amanneɛ ansa na woakɔhwehwɛ ayaresa.
- Sɛ wuhu sɛnkyerɛnne ahorow te sɛ ɔbrɛ a ɛtra so mpofirim, wo honam ani yɛ kɔkɔɔ, anaa wo nsu a ɛyɛ tuntum a, kɔ wo duruyɛfo nkyɛn ntɛm ara.
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