So wo duruyɛfo akyerɛw aduru bi a ɛbɛma wo srade a ɛwɔ wo mu no so atew? Ebia worenom mpo. Wɔfrɛ eyinom statin ahorow. Wɔboa ma yɛbɔ yɛn ho ban fi nyarewa a emu yɛ den te sɛ komayare ne akisikuru ho. Nanso ɛtɔ mmere bi a, saa nnuru yi betumi ama obi ho ayɛ no yaw, titiriw ntini mu yaw. Sɛ saa a, asɛm yi bɛyɛ nea ɛho hia wo paa. Ɛnnɛ yɛrebɛka ɔhaw bi a nnipa pii wɔ ho asɛm, a wɔfrɛ no ‘statin intolerance’.
Nea edi kan no, ma yɛnhwɛ, dɛn ne statin? Dɛn nti na wɔde di dwuma?
Sɛ yɛbɛka no tiawa a, statin yɛ nnuru bi a nnuruyɛfo kyerɛw ma sɛ ɛbɛma srade "bɔne" a ɛwɔ yɛn mmerɛbo ne yɛn mogya mu no so atew. Ebia woate din ahorow yi ho asɛm: Atorvastatin, Rosuvastatin, Simvastatin yɛ statin ahorow a wɔtaa de di dwuma wɔ Sri Lanka no bi.
Afei momma yɛnte srade a ɛwɔ nipadua mu no ase kakra. Fa no sɛ yɛwɔ srade ahorow abien wɔ yɛn nipadua mu. Baako te sɛ adamfo pa , na ɔfoforo nso te sɛ ɔtamfo bɔne .
- Cholesterol pa (HDL): Dodow a yɛwɔ eyinom pii wɔ yɛn nipadua mu no, dodow no ara na eye, efisɛ ɛbɔ yɛn ho ban fi nyarewa te sɛ komayare ne akisikuru ho.
- Cholesterol bɔne (LDL): Eyinom ne yɛn atamfo. Sɛ wɔdɔɔso wɔ mogya no mu a, ɛkɔhyɛ yɛn mogya ntini mu, na esiw mu na ɛma asiane a ɛwɔ hɔ sɛ yebenya komayare ne akisikuru no yɛ kɛse.
Statin nnuru yɛ adwuma denam srade bɔne (LDL) dodow a ɛso tew so. Enti, saa nnuru yi boa nnipa a asiane a ɛwɔ hɔ sɛ wobenya komayare no ma wɔtra ase yiye na wɔtra ase kyɛ.
Enti, dɛn ne ‘statin a wontumi nnye ntom’?
Statin a wontumi nnye ntom ne bere a nea efi statin bi mu ba no dɔɔso sen mfaso a ɛwɔ so no. Wei kyerɛ sɛ wo nipadua ntumi "nnye" aduru no ano. Eyi betumi ayɛ akisikuru anaasɛ ade foforo a enye.
Sɛ eyi ba a, wuntumi mfa aduru no nni dwuma mfa ntew wo srade so bio. Mpɛn pii no, sɛnkyerɛnne titiriw ne ntini mu yaw, ɛyɛ mmerɛw, anaa mmerɛwyɛ .
Nsɛnkyerɛnne a ɛtaa ba a ɛkyerɛ sɛ ‘Statin Intolerance’.
Sɛ woafi ase de statin redi dwuma a, hwɛ yiye wɔ saa sɛnkyerɛnne ahorow yi ho.
| Fa nsa hyɛ aseɛ | Nkyerɛmu |
|---|---|
| Ntini mu yaw | Ɛte sɛ nea woretow wo ho kɛkɛ, na wo ntini reyɛ wo yaw. |
| Nipadua a nkwa nnim | Sɛ wote nka sɛ woayɛ mmerɛw araa ma wuntumi nyɛ nnwuma a ɛfata mpo. |
| Nipadua mu yaw | Ɛyaw ne ɛyaw a ɛkɔ so wɔ nkwaa ne ntini mu. |
Nea ɛho hia sen biara: Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa ansa na woagyae aduru no. Mpɛn pii no, saa sɛnkyerɛnne ahorow yi fi hɔ bere a woagyae aduru no nom akyi. Nanso, sɛ wokɔ so nya saa sɛnkyerɛnne ahorow yi na wokɔ so nom aduru no a, ebia wobɛkɔ asiane mu sɛ wobɛsɛe wo ntini daa.
Dɛn ne asiane ahorow a ɛma obi nya ‘Statin Intolerance’?
Ɛda adi sɛ nnipa binom benya saa tebea yi. Momma yɛnkyekyɛ asiane ahorow yi mu abien. Ebinom yɛ yentumi nsakra, nanso ebinom nso yetumi di ho dwuma.
| Asiane a ɛde ba no su | Nhwɛso ahorow |
|---|---|
| Nneɛma a ɛnsakra |
|
| Nneɛma a wotumi di ho dwuma |
|
Ɔkwan bɛn so na oduruyɛfo tumi hu saa tebea yi pɛpɛɛpɛ?
Sɛ wokɔ wo duruyɛfo nkyɛn a, obedi kan abisa wo yare no ho sɛnkyerɛnne, nnuru foforo biara a worenom, ne w’abusua aduruyɛ ho abakɔsɛm. Afei, ebia wɔbɛyɛ nhwehwɛmu ahorow bi de ahu sɛ ebia statin ahorow no na ɛde wo sɛnkyerɛnne ahorow no reba anaasɛ aduruyɛ mu tebea foforo bi wɔ hɔ anaa.
- Mogya mu nhwehwɛmu: Eyinom boa ma woyi mmerɛbo mu enzymes, ntini mu enzymes (Creatine Kinase), ne ayaresa mu tebea afoforo fi hɔ.
- Ntini mu sɔhwɛ: Hwɛ sɛ ntini mu mmerɛwyɛ anaa.
- Nhwehwɛmu afoforo: Ebia wɔbɛkamfo akyerɛ sɛ wɔnyɛ awosu mu nhwehwɛmu anaa ntini mu nhwehwɛmu, nanso mpɛn pii no wɔntaa nyɛ eyinom.
Sɛ wowɔ ‘statin a wontumi nnye ntom’ a, dɛn ne ano aduru a ebetumi aba?
Fa no sɛ oduruyɛfo no asi gyinae sɛ wowɔ saa yare yi. Nha wo ho. Ano aduru pii wɔ hɔ a wobetumi de adi dwuma.
1. Nnuru dodow a wobɛsesa: Ebia wo duruyɛfo bɛtew statin dodow a wode di dwuma no so, anaasɛ obegyae nnuru no nom kakra ahwɛ sɛ wo yare no ho sɛnkyerɛnne no tu mpɔn anaa. Ɛtɔ da bi a, ebia wɔbɛdan wo akɔ statin foforo so.
2. Nnuru afoforo a ɛnyɛ statin: Sɛ wontumi mfa statin nni dwuma a, nnuru afoforo wɔ hɔ a ɛma mogya mu srade so tew.
- Nnuru a esiw ACL ano: Eyinom siw srade bɔne (LDL) a mmerɛbo no yɛ ano.
- PCSK9 inhibitors: Eyinom siw protein titiriw bi a ɛwɔ yɛn nipadua mu ano na ɛboa ma woyi srade bɔne (LDL) fi nipadua no mu.
- Fibrates: Eyinom boa ma srade bɔne (LDL) so tew bere a ɛma srade pa (HDL) nso kɔ soro no.
- Bile acid sequestrants: Eyinom siw srade a ɛsan nkɔ mogya no mu no ano.
3. Asetra mu nsakrae: Eyi ho hia paa. Sɛ wonom nnuru anaasɛ woannom a, saa nneɛma yi betumi aboa ma woadi wo srade dodow so.
- Aduan a ahoɔden wom: Di ngo, asikre, ne nkyene kakraa bi, na di nhabannuru, nnuaba, ne nhabannuru pii.
- Apɔw-mu-teɛteɛ: Yɛyɛ biribi te sɛ nantew anaa asuguare da biara da.
- Subammɔne a wobegyae: sigaretnom ne nsanom a wobegyae.
4. Nnuru a wɔde ka ho: Wɔ tebea horow bi mu no, ebia wo duruyɛfo bɛkamfo akyerɛ sɛ fa nnuru a wɔde ka aduan ho te sɛ vitamin D anaa Coenzyme Q10 (CoQ10) na aboa ma ntini mu yaw so atew. Nanso, ɛho hia sɛ wokɔ wo duruyɛfo nkyɛn ansa na woafi eyinom ase.
Nkrasɛm a Wɔde Kɔ Fie
- Statins yɛ aduru a ɛho hia yiye a wɔde tew srade so na ɛbɔ obi ho ban fi komayare ho. Nanso, wobetumi de ɔhaw ahorow aba nnipa binom so.
- Ntini mu yaw ne mmerɛwyɛ ne ‘Statin Intolerance’ ho sɛnkyerɛnne atitiriw. Hwɛ eyinom so yiye.
- Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, w’ankasa nnyae w’aduru nom da. Di kan ne wo duruyɛfo nkasa.
- Sɛ wowɔ ‘statin a wontumi nnye ntom’ mpo a, nnuru afoforo ne akwan a wobɛfa so asiw wo srade so wɔ hɔ. Enti mma ɛnhaw wo.
- Asetra pa a wobɛkɔ so akura mu no ho hia na ama woatumi adi srade a ɛwɔ mogya mu no so.
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