Have you ever donated blood? When we usually donate blood, we give our whole blood. But did you know that there is a special method that can separate the different parts of our blood, such as red blood cells, white blood cells, and platelets, or remove only the harmful parts that cause a certain disease from the blood? That wonderful medical method is called apheresis. Some people also call this pheresis. Let's talk about this simply today.
Simply put, what is apheresis?
Think of it like separating the curds from the milk after squeezing a coconut. Apheresis is a similar process. In this process, a special machine, called a centrifuge, spins the blood taken from your body very fast and separates the different components (parts) in it. This separates the blood, takes only the part you need (for example, healthy platelets), and injects the rest of the blood back into your own body. This method is used for two main purposes: 1.
For blood donation: Donate only the part of your blood that is needed by another patient, such as red blood cells, platelets, or plasma. 2.
As a treatment: Remove abnormal or harmful blood parts (for example,
cancer cells ) that are causing a disease in your body.
What are the main types of apheresis?
This treatment method is done in different ways depending on the need. To understand it exactly, see the table below.
| Type of Apheresis | What does this do? (What it does) |
|---|
| Leukapheresis | Removing the uncontrolled growth of harmful white blood cells from the blood. This relieves symptoms. |
| Peripheral blood stem cell collection | Collecting immature stem cells from the blood required for a stem cell transplant. |
| Photopheresis | A type of white blood cell called lymphocytes, which are removed from the body, is exposed to UVA light, boosted in function, and then reintroduced into the body. This increases the ability to fight things like cancer cells and viruses. |
| Plasmapheresis (plasma exchange) | Removing the liquid part of the blood, plasma, and replacing it with healthy plasma or another fluid. This is used for a number of serious illnesses. |
| Platelet depletion | If the body has too many platelets, which help blood clot, the excess platelets are removed. |
| Red blood cell exchange | Removing unhealthy, abnormal red blood cells (e.g., in sickle cell anemia) and replacing them with healthy, donated red blood cells. |
What diseases is this treatment used for?
Apheresis is a very important method in the treatment and management of many diseases. For example, healthy stem cells from a person undergoing strong chemotherapy for cancer can be removed, stored safely, and returned after treatment. This treatment is mainly used for the following conditions:
Blood Cancers
Other blood disorders
Neurologic Disorders
In addition, apheresis is also used to treat conditions such as organ transplant rejection and graft vs. host disease.
How should I prepare for this?
This is done for different reasons, so not everyone has to prepare in the same way.
So the best thing to do is to follow your doctor's instructions exactly. He or she will clearly tell you how long the treatment will take and what you need to do before it. For example, if you are a stem cell donor, you will need to take a medicine a few days before the treatment. This helps the stem cells in your bone marrow to enter your blood faster. In general,
it is a good idea to drink plenty of fluids, such as water, for a few days before the treatment. What happens during apheresis?
Although this may sound like a big deal, it's actually done very systematically, in a way that makes you feel at ease.
- First, you will be made to sit/reclin in a comfortable chair or bed.
- Then, the medical staff will insert two needles into a vein in each of your arms. Each needle will have a catheter , a thin, flexible tube, attached to it.
- On the one hand, some of your blood goes into that special machine. Inside the machine, the blood components have to be separated.
- Then, the required portion is separated, and the remaining blood is injected back into your body through the tube in the other arm.
While this entire process is happening, you can read a book, listen to a song, or just relax.
There is no need to be afraid because the medical staff will always be with you. What are the possible risks after this treatment?
As with any medical procedure, there are some very rare risks involved. But these are usually minor. Also, since the medical team is monitoring you throughout the procedure, if any problems arise, they can address them right away.
| Risk/Complication | Simply put... |
|---|
| Low blood pressure (Hypotension) | Your blood pressure may drop slightly because some blood is removed from your body and fluids are given to prevent blood clots. You may feel dizzy. |
| Low calcium levels (Hypocalcemia) | Anticoagulants can temporarily lower calcium levels in the body, causing numbness around the lips and extremities. |
| Bleeding | There may be a little bleeding from the insertion site. |
| Infection | Very rarely, there is a chance of infection at the insertion site. |
| Nerve damage | Very rarely, numbness or weakness may occur due to pressure on a nerve during insertion of the needle. |
Remember, the chances of these things happening are very low. If you feel any discomfort, numbness, or dizziness , notify the medical staff immediately.
When should I call the doctor?
After treatment, you can usually resume your daily activities. Your doctor will explain to you what minor symptoms you can expect after treatment.
If your symptoms are more severe than he or she says, or if you have any concerns or concerns, call your doctor right away. Take-Home Message
- Apheresis is a special medical procedure used to separate the different components of blood.
- This involves either donating a portion of the blood or removing and treating the diseased parts.
- This is a very safe treatment performed under medical supervision, so don't be afraid.
- Follow your doctor's instructions carefully before and after treatment.
- If you experience any discomfort during or after treatment, inform the medical staff or your doctor immediately.
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