Yala i delila k’i yɛrɛ ɲininka cogo min na, n’i ye farigan minɛ, a bɛ kɛnɛya tile damadɔ kɔnɔ wa? K’a sɔrɔ an m’a dɔn, an farikolo bɛ ni lafasali sira kabakoma ye, i n’a fɔ kɛlɛbolo, min bɛ baara kɛ an kɔnɔ walasa k’an tanga banaw ma. Sɔrɔdasi minnu nafa ka bon kosɛbɛ, minnu kɛrɛnkɛrɛnnen don o sigida la, olu bɛ wele ko T-cell sitotoxiques. Bi, an bɛna kuma nin cɛfarin fitinin ninnu kan.
Nin T-cell sitotoxiques ninnu ye mun ye?
N’an y’a fɔ cogo nɔgɔman na, T-cell sitotoxiques ye selilɛri sugu dɔ ye an farikolo tangacogo la . U bɛ i n’a fɔ kɛlɛbolo kɛrɛnkɛrɛnnen sɔrɔdasi minnu bɛ an ka jamana kɛlɛbolo la. U ka baara kunba ye ka banakisɛw sɔrɔ minnu bɛ don an fari la, ka olu sɔrɔ ani k’u tiɲɛ . O de y'a To u bɛ Weele fana ko "Killer T cells".
o T-cell ninnu bɛ sɔrɔ glande fitini dɔ la an disi ɲɛfɛ min bɛ wele ko thymus . Timis gland bɛ T-cell suguya saba belebeleba dilan.
| T-cell suguya | Baara ka nɔgɔn. |
|---|---|
| T-cell minnu bɛ kɛ sitotokisi ye | Ka farikolokisɛ jugumanw dɔn ani k’u tiɲɛ, i n’a fɔ banakisɛfagalanw ni kansɛribanakisɛw. |
| Dɛmɛbaga T-cellw | Banakisɛfagalanw ka farikolokisɛ wɛrɛw lawulili ani k’u dɛmɛ u ka kɛlɛ kɛ. I n’a fɔ sɔrɔdasi ɲɛmɔgɔ dɔ. |
| T-celles régulatrices (T-celles régulateurs) ye | Ni kɛlɛ banna, farikolo tangalanw ka walew bɛ kunbɛn ani a bɛ farikolokisɛ kɛnɛmanw tiɲɛni dabila kun tɛ. |
O selilɛriw bɛ baara kɛ cogo di?
Banakisɛfagalan suguya fila de bɛ yen. Kelen ye farikolo tangacogo bangenen ye , o ye farikolo tangalan ye min bɛ an farikolo la n’an bangera. Tɔɔ kelen ye farikolo tangacogo ye min bɛ se ka ladamu.O kɔrɔ ye ko n’an ye banaw sɔrɔ walima n’an ye bolociw sɔrɔ, an farikolo bɛ lafasali fɛɛrɛ kɛrɛnkɛrɛnnen dɔ labɛn.
T-cell sitotoxiques ye nin farikolo tangacogo suguya filanan in yɔrɔ nafamaba ye min bɛ se ka ladamu. O kɔrɔ ye ko o farikolokisɛw degecogo bɛ banakisɛ kɛrɛnkɛrɛnnen dɔ dɔn ani k’a kɛlɛ.
Danfara bɛ T-cell sitotoxiques ni nature killer cellules cɛ
N’a sɔrɔ aw ye Natural Killer selilɛriw fana ko mɛn. Hali n’u fila bɛɛ ye ‘fagali’ selilɛriw ye, danfara dɔɔnin bɛ u ni ɲɔgɔn cɛ.
- Natural Killer cellules: Olu ye farikolo tangacogo bangenen dɔ ye. O kɔrɔ ye k’u mago tɛ dege kɛrɛnkɛrɛnnen na walima baarakɛcogo la walasa ka bin selilɛri jugu dɔ kan. U bɛ to ka kɔlɔsili kɛ dɔrɔn.
- T-cell sitotoxiques : Olu ye farikolo tangacogo ladamucogo dɔ ye. Walasa u ka se ka bin banakisɛfagalan dɔ kan, u ka kan ka bana in dɔn fɔlɔ ani ka baara kɛ.
Kɛlɛ daminɛ cogo
Sitotokisi T-cellw bɛ ni ‘antɛni’ kɛrɛnkɛrɛnnen ye u ɲɛda la min bɛ wele ko CD8 minɛbaga . An farikolo kɔnɔ selilu kelen-kelen bɛɛ bɛ se ka kɛ ni "identification card" ye a ɲɛda la. A bɛ fɔ a ma ko MHC Class I molekilɛri . Ni banakisɛ dɔ ye selilɛri dɔ minɛ, o seli bɛ banakisɛ yɔrɔ fitinin dɔ bila nin ID karti in kan a ɲɛda la, k’a jira ko “jugu dɔ filɛ nin ye ne kɔnɔ.”
O waati de la an ka T-cell ka CD8 antɛni bɛ o taamasiɲɛ in ta. O kɔfɛ, T-cell bɛ kɛ baarakɛta ye, ka kemikɛlifɛnw dilan minnu ka kan ka kɛ walasa ka banakisɛ in tiɲɛ.
Ani fana, ni dɛmɛbaga T-cellw ye banakisɛ dɔ ye, u bɛ cidenw bɔ minnu bɛ wele ko sitokiniw . O cikanw bɛ T-cell sitotoxiques (banakisɛfagalanw) lawuli ka taa a fɛ walasa u ka fara kɛlɛ kan.
O T-cellw bɛ min an farikolo la?
T-cellw bɛ u ka ɲɛnamaya daminɛ an ka kolotugudaw la . O kɔ, i n’a fɔ farikolokisɛ minnu ma kɔgɔ, u bɛ taa timis gland la an disi la. Timisi bɛ i n’a fɔ T-cellw ka kalanso. O yɔrɔ de la, o seliw bɛ kɔgɔ ani k’a dɔn u ka baara ye min ye. Degeli kɔfɛ, o farikolokisɛw bɛ yaala farikolo fan bɛɛ la.
T-cell caman bɛ an ka ɲɛgɛnɛsira bɛɛ la , kɛrɛnkɛrɛnnenya la. T-cell hakɛ caman bɛ se ka sɔrɔ ninnu na:
- Kolotugudaw
- Banakɔtaa
- Fogonfogon
- Lymph nodes (nɔgɔsɔgɔninjɛ).
- Sɔgɔsɔgɔninjɛ
- Tonsiw (tonsiliw).
Bana jumɛnw bɛ T-cellw minɛ?
Tuma dɔw la, an farikolo tangalanw bɛ se ka baara kɛ ka ɲɛ. Bana damadɔ bɛ yen minnu bɛ nɔ bila T-cell la.
- Bana minnu bɛ sɔrɔ farikolo tangalanw fɛ:Min bɛ kɛ nin ko ninnu na, o ye ko an yɛrɛ ka farikolo tangalanw bɛ bin an yɛrɛ ka farikolokisɛ kɛnɛmanw kan.
- Jolidɛsɛ jugumanba : Nin ye kansɛri suguya dɔ ye min bɛ daminɛ joli ni kolotugudaw la.
- Balikuw ka Hodgkin lymphoma : Nin ye kansɛri suguya dɔ ye min bɛ daminɛ farikolojidɛsɛbanakisɛw la.
- Sidabanakisɛ : Nin banakisɛ in bɛ bin an farikolo tangalanw kan, kɛrɛnkɛrɛnnenya la T-cellw.
- Job syndrome: Nin ye farikolo tangacogo bana ye min man teli ka sɔrɔ, a bɛ kɛ sababu ye ka banakisɛw bila mɔgɔ la tuma caman.
- Aplasie thymique : T-cell dilanni bɛ tiɲɛ ka a sababu kɛ thymus gland tɛ yiriwa ka ɲɛ bange waati.
An bɛ se ka fɛn minnu kɛ walasa an farikolo tangacogo ka to barika la
Fɛn nɔgɔman caman bɛ yen an bɛ se ka minnu kɛ walasa an ka lafasalitɔn kabakoma ka to kɛnɛya la ani ka barika sɔrɔ.
- Aw bɛ aw yɛrɛ tanga dɔlɔ ma walima ka dan sigi a la kosɛbɛ.
- Aw bɛ dumuni dafalen dun. Aw bɛ jiridenw, nakɔfɛnw, shɔ, sogo mɔbaliw, jɛgɛ, nɔnɔmugu ani dumuni nafama caman fara a kan.
- Aw bɛ to ka farikoloɲɛnajɛ kɛ. Aw bɛ farikoloɲɛnajɛ suguya caman kɛ i n’a fɔ taama, boli ani girinya kɔrɔta.
- Aw bɛ sunɔgɔ ɲuman kɛ. Aw bɛ aw jija ka sunɔgɔ fo lɛri 7-8 tile kɔnɔ.
- Aw ye aw yɛrɛ tanga sigarɛtimin ni sigarɛtimin ma pewu. Ni aw mago bɛ dɛmɛ na walasa ka nin delina in dabila, aw bɛ kuma aw ka dɔgɔtɔrɔ fɛ o ko la.
- Aw bɛ to ka aw tɛgɛw ko ni safinɛ ni ji ye. O bɛ se ka kɛ sababu ye ka banakisɛw bali ka don aw fari la.
Take-Home cikan
- T-cell sitotoxiques ye sɔrɔdasi kulu kɛrɛnkɛrɛnnen ye an ka farikolo tangalanw na minnu bɛ juguw tiɲɛ, i n’a fɔ banakisɛw ni kansɛribana.
- O farikolokisɛw bɛ kɔgɔ ani ka dege an farikolo ka thymus gland kɔnɔ.
- Dɛmɛbaga T-cellw bɛ i n’a fɔ cidenw minnu bɛ o mɔgɔfagalaw bila ka kɛlɛ kɛ.
- Fɛn nɔgɔmanw i n’a fɔ dumuni dafalen, sunɔgɔ ɲuman, farikoloɲɛnajɛ, ani sigarɛtiminbaliya, olu bɛ se ka an farikolo tangacogo barika bonya.
- Ni haminanko dɔw bɛ aw farikolo tangacogo la walima ni aw bɛ to ka bana, a ka fisa aw ka kuma aw ka dɔgɔtɔrɔ fɛ o ko la.
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