Yala aw delila ka HTLV-1 (Human T-lymphotropic Virus type-1) ko mɛn wa? An ka kuma o kan!

N’a sɔrɔ aw ye banakisɛw mɛn i n’a fɔ SIDA. Nka a bɛ se ka kɛ aw ma caman mɛn banakisɛ HTLV-1 kan. Nin fana ye banakisɛ suguya dɔ ye min bɛ se ka don an fari la ka bana bila mɔgɔ la. Nka aw kana aw hakili ɲagami, mɔgɔ fanba fɛ o tɛna kɛ gɛlɛyaba ye. Nka a ka ɲi k’a dɔn, tiɲɛ tɛ? O la, an k’a lajɛ HTLV-1 ye mun ye, a bɛ yiriwa cogo min na, ani min bɛ se ka kɛ a la.

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HTLV-1 ye mun ye? An k’a faamu cogo nɔgɔman na!

HTLV-1 kɔrɔ ye Hadamaden ka T-lymphotropic Virus type-1 ye . Nin ye banakisɛ kulu dɔ ye min bɛ wele ko Retrovirus. Aw hakili b’a la ko an kumana SIDA (VIH) banakisɛ kan ka kɛ Retrovirus ye wa? Nin Retrovirus ninnu ka kɛrɛnkɛrɛnnen dɔ ye ko n’u donna an ka seliluw kɔnɔ, u ka jamu kunnafoniw, n’o ye u ka genetic material ye, olu bɛ don an ka seliluw ka ADN (ADN) kɔnɔ. Miiri k’a filɛ i n’a fɔ banakisɛ dɔ donna ɔridinatɛri kɔnɔ.

VIH banakisɛ ni HTLV-1 banakisɛ fila bɛɛ bɛ bin T cellules kan an ka farikolo tangacogo la. Nka u bɛ baara kɛ cogo min na, o tɛ kelen ye kosɛbɛ. VIH bɛ T cellules tiɲɛ ani ka farikolo tangalanw fanga dɔgɔya. Nka HTLV-1 tɛ o T-cell suguw tiɲɛ. Tiɲɛ na, mɔgɔ caman minnu banana ni HTLV-1 ye, olu tɛ taamasiɲɛ foyi jira. U bɛ balo i n’a fɔ mɔgɔ kɛnɛmanw.

Nka, bana in bɛ mɔgɔ minnu na, olu hakɛ fitinin dɔrɔn de bɛ bana fila sɔrɔ san caman kɔfɛ, laala san 30 fo san 60 o kɔfɛ. Kelen ye joli kansɛri suguya dɔ ye min bɛ wele ko Adult T-cell Leukemia/Lymphoma (ATL walima ATLL). Tɔɔ kelen ye farikolojidɛsɛbana ye min bɛ wele ko HTLV-1- associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).

Yala HTLV suguya wɛrɛw bɛ yen wa?

Ɔwɔ, HTLV banakisɛ suguya caman bɛ yen minnu bɛ hadamadenw minɛ. Misali la, HTLV-1, HTLV-2, HTLV-3 ani HTLV-4 bɛ yen. Ninnu bɛɛ bɛ na ni bana ye a si bɛɛ la. Nka, fo ka na se bi ma, HTLV-1 dɔrɔn de bɛ bana kɛrɛnkɛrɛnnenw lase mɔgɔ ma.

Nin HTLV-1 in ka ca cogo di? Yala a bɛ Sri Lanka jamana na wa?

HTLV banakisɛ bɛ sɔrɔ diɲɛ yɔrɔ caman na. Fɛn dɔnbagaw y’a jira ko mɔgɔ miliyɔn 5 ni 20 cɛ diɲɛ kɔnɔ, HTLV-1 bana bɛ u la. Nka, banakisɛ sɔrɔli hakɛ bɛ danfaraba don jamanaw ni maraw cɛ.

Misali la, Ameriki Woroduguyanfan na, a bɛ jamanaden 1% bɔ. Nka, Zapɔn, Afiriki, Ameriki saheliyanfan, Ɔsitarali, Iran ani Karayibu jamana yɔrɔ dɔw la, a fɔra ko nin bana in bɛ mɔgɔ tila sabanan ni kɔ la. A ka gɛlɛn ka kunnafoni jɛlenw sɔrɔ Sri Lanka jamana ka ko kɛlenw kan, nka a nafa ka bon ka o banakisɛ suguw dɔn.

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O taamasiɲɛw ye mun ye? Yala o bɛ kɛ bɛɛ la wa?

I n’a fɔ a fɔra cogo min na ka tɛmɛ,HTLV-1 banakisɛ bɛ mɔgɔ minnu na, olu fanba tɛ taamasiɲɛ foyi jira. U yɛrɛ t’a dɔn ko banakisɛ in b’u la. A taamasiɲɛw bɛ ye san caman dɔrɔn banakisɛ sɔrɔlen kɔfɛ, ni bana minnu kofɔra ka tɛmɛ, i n’a fɔ ATL walima HAM/TSP, olu bɛ sɔrɔ.

ATL (Adult T-cell Leukemia/Lymphome) taamasiɲɛw bɛ se ka kɛ:

Ka sɛgɛn tuma bɛɛ (Sɛgɛn) .
Fari kurukuruw, bana minnu bɛ i n’a fɔ ŋɛɲɛ
Nɔgɔmugu funu – i n’a fɔ kɔ, kɔkili, ani kɔkolo
Kɔnɔja
Hakilila tiɲɛni, hakili ɲagami
Kolow dimi

HAM/TSP (HTLV-1-associé myopathie/tropical spastic paraparesis) taamasiɲɛw bɛ se ka kɛ:

Farikantan walima gɛlɛya min bɛ bonya dɔɔni dɔɔni sen kelen walima sen fila bɛɛ la
Kɔdimi
Sugunɛbilenni
Farikolo yɔrɔw sɔgɔsɔgɔ, sɔgɔsɔgɔninjɛ (Périphérique neuropathie) .

Bana wɛrɛ jumɛnw bɛ se ka sɔrɔ HTLV-1 fɛ?

Mɔgɔ 20 o 20 (5% ɲɔgɔn) minnu bɛ HTLV-1 banakisɛ sɔrɔ, olu kelen ɲɔgɔn bɛ bana dɔw sɔrɔ minnu bɛ wele ko ATL (kansɛri) walima HAM/TSP (sɔgɔsɔgɔninjɛ).

ATL ye kansɛri suguya dɔ ye min bɛ sɔrɔ joli la . A suguya fitinin damadɔ fana bɛ yen (i n’a fɔ acute, lymphome, smoldering, chronic). A suguya kelen-kelen bɛɛ furakɛcogo ni a ɲɛfɔcogo bɛ se ka ɲɔgɔn ta dɔɔni.
HAM/TSP ye bana ye min bɛ farikolo yɔrɔw minɛ. A ni bana min bɛ wele ko Sclerose multiple (MS) bɛ tali kɛ ɲɔgɔn na dɔw. A bɛ farikolo fanga dɔgɔya ani ka gɛlɛyaw lase farikolo yɔrɔw ma minnu bɛ taa ɲɛ.

Ka fara nin banaba fila ninnu kan, ɲininikɛlaw y’a ye ko HTLV-1 bɛ se ka funu ni farikolo tangacogo bana dɔw fana lase mɔgɔ ma . Nka, jɛɲɔgɔnya tigitigi min bɛ u ni ɲɔgɔn cɛ, o ma jɛya hali bi. O bana dɔw ye ninnu ye:

Farikolodimi
Jolidɛsɛbana
Ɲɛ kɔnɔna yɔrɔw fununi (Uveitis) .
Sjögren ka bana dɔ

Bana minnu bɛ sɔrɔ HTLV-1 fɛ, olu bɛ sɔrɔ cogo di? Mun na bɛɛ tɛ u sɔrɔ?

Ni HTLV-1 banakisɛ donna an farikolo la, a bɛ taa ɲɛfɛ ka taa CD4 selilɛriw la (a bɛ fɔ fana ko dɛmɛbagaw T-cells) an farikolo tangalanw na. Nin CD4 selilɛriw bɛ i n’a fɔ an farikolo polisiw, selilɛri suguya dɔ min bɛ dɛmɛ ka an tanga banaw ma.

Sisan, retrovirusiw i n’a fɔ HTLV-1, olu b’u ka jamu kunnafoniw ta fɛnɲɛnamafagalan dɔ kɔnɔ min bɛ wele ko ARN. Ni u donna an ka selilɛriw kɔnɔ, banakisɛ bɛ a ka ARN caman tigɛli kɛ ni hakilitigiya ye ka kɛ fɛn ye min ni ADN bɛ tali kɛ ɲɔgɔn na, an ka selilɛriw ka kunnafoniw bɛ min kɔnɔ. O kɔfɛ, a ye ADN yɔrɔ min dilan (a bɛ fɔ o ma ko provirus) o bɛ don an ka selilɛriw yɛrɛ ka ADN kɔnɔ. O kɔrɔ ye ko banakisɛ bɛ a yɛrɛ yɔrɔ dɔ don porogaramu kɔnɔ min bɛ an ka selilɛriw kɔlɔsi.

Sisan an ka seliluw, n’u b’a miiri ko banakisɛ in ADN yɔrɔ dɔ ye u yɛrɛ ta ye, u bɛ daminɛ ka banakisɛ in kopi caman dilan. Nin HTLV banakisɛ kopi kura minnu dilannen don, olu bɛ taa CD4 banakisɛ caman wɛrɛw minɛ. Hali ni banakisɛ in jɛnsɛnna farikolo la nin cogo la, a ka ca a la a tɛ taamasiɲɛ foyi lase mɔgɔ ma.

Nka, mɔgɔ dɔw la, san caman tɛmɛnen kɔfɛ, o bana in bɛ kɛ sababu ye u farikolo ka T-cell caman bɔ. O waati de la bana dɔ bɛ sɔrɔ min bɛ wele ko ATL jolidɛsɛ. Ni a kɛra cogo wɛrɛw la, nin banakisɛ in bɛ se ka farikolo yɔrɔw minɛ ka bana dɔ lase mɔgɔ ma min bɛ wele ko HAM/TSP. Mun na o bɛ Kɛ mɔgɔ dɔw dɔrɔn de la, o bɛ Sɛgɛsɛgɛ hali bì.

Nin HTLV-1 banakisɛ in bɛ bɔ mɔgɔ dɔ la ka taa mɔgɔ wɛrɛ la cogo di?

Fɛɛrɛba damadɔ bɛ yen minnu bɛ se ka kɛ sababu ye ka HTLV-1 banakisɛ sɔrɔ. A nafa ka bon kosɛbɛ ka ninnu dɔn:

Cɛnimusoko sababu fɛ: musoya, musoya walima da la, a lakananen tɛ.
Ka bɔ ba la ka taa den na sinji dili fɛ: Ni denba min bananen don, o bɛ sin di a den ma.
Ni aw bɛ pikirijikɛlanw tila ɲɔgɔn na : Kɛrɛnkɛrɛnnenya la mɔgɔ minnu bɛ dɔrɔgu pikiri kɛ.
A man teli: Joli tali fɛ walima farikolo yɔrɔw cili fɛ. Nka, jamana caman na, joli ni farikolo yɔrɔw dicogo bɛ sɛgɛsɛgɛ sisan banakisɛ in na, o la a jɛnsɛnni o fɛɛrɛ ninnu fɛ, o man teli ka kɛ.

Jɔn de farati ka bon ka HTLV-1 sɔrɔ?

Fɛn caman bɛ yen minnu bɛ dɔ fara HTLV-1 banakisɛ sɔrɔli kan:

Fura pikiri kɛli ni furasɛbɛn tɛ a la.
Ka bange walima ka sigi yɔrɔ la, HTLV banakisɛ ka ca yɔrɔ min na.

Yɔrɔ dɔw la HTLV-1 banakisɛ ka ca yɔrɔ minnu na, olu ye:

Japon saheli-tlebi fɛ
Farafinna jamanaw Sahara kungo saheliyanfan fɛ (Sub-Sahara Africa)
Ameriki saheli fan dɔw
Karayibu gunw
Iran woroduguyanfan fɛ
Ɔsitarali cɛmancɛ la

Nafama: Hali jamana kelen kɔnɔ, banakisɛ sɔrɔli hakɛ tɛ kelen ye yɔrɔ bɛɛ la. Yɔrɔ fitini dɔw bɛ se ka kɛ banakisɛ sɔrɔli hakɛ ka ca, hali ni a bɛɛ lajɛlen hakɛ ka dɔgɔn.

Gɛlɛya jumɛnw bɛ se ka sɔrɔ HTLV-1 banakisɛ sɔrɔli fɛ?

HTLV-1 banakisɛ kelen tɛ farikolo tangacogo fanga dɔgɔya. Nka ni ATL (kansɛri) walima HAM/TSP (sɔgɔsɔgɔninjɛ) banana, farikolo tangalanw bɛ se ka fanga dɔgɔya.O bɛ se ka kɛ sababu ye ka banakisɛw sɔrɔ minnu bɛ se ka kɛ sababu ye, banakisɛ minnu tɛ sɔrɔ mɔgɔ kɛnɛmanw na. Nin bana ninnu dɔw bɛ se ka mɔgɔ ka ɲɛnamaya bila farati la.

Aw bɛ HTLV-1 banakisɛ dɔ dɔn ka ɲɛ cogo di ?

Dɔgɔtɔrɔw bɛ HTLV-1 banakisɛ sɛgɛsɛgɛ ni joli sɛgɛsɛgɛli ye. Nin sɛgɛsɛgɛli in bɛ farikolo tangalanw (anticorps) ɲini minnu bɔra farikolo la ka HTLV banakisɛ kɛlɛ, walima ni banakisɛ in ka jamu (ARN) bɛ yen.

Nka, o tɛ kɔrɔbɔli ye min bɛ kɛ tuma bɛɛ bɛɛ fɛ. Dɔgɔtɔrɔ bɛ se ka aw bila ka taa nin sɛgɛsɛgɛli in kɛ nin ko ninnu na:

Ni furakɛli cogoya dɔ bɛ aw la (misali la, ATL walima HAM/TSP taamasiɲɛw) aw hakili la ko a bɛ se ka kɛ sababu ye ka HTLV-1 banakisɛ sɔrɔ.
Ni aw sigilen bɛ yɔrɔ la, HTLV banakisɛ ka ca yɔrɔ min na, ni aw bɛ ka sin di den ma.
Ni aw jigi b’a kan ka kɛ joli dibaga ye walima farikolo yɔrɔw dibaga ye (o ye sɛgɛsɛgɛli wajibiyalen ye sisan yɔrɔ caman na).

Yala fura bɛ HTLV-1 la wa? Yala a bɛ se ka furakɛ wa?

Ni an b’a fɛ ka tiɲɛ fɔ, fura si ma sɔrɔ fɔlɔ HTLV-1 banakisɛ in na. O kɔrɔ ye ko banakisɛ tɛ se ka bɔ farikolo la pewu. Nka, furakɛli dɔw bɛ yen banaw ATL ni HAM/TSP la minnu bɛ sɔrɔ HTLV-1 fɛ.

Olu bɛ kɛ furaw ye ATL (kansɛri) la:

Fura minnu bɛ kɛ ka ɲɛgɛnɛsiralabanaw suguya wɛrɛw furakɛ, misali la, chimiothérapie .
Banakisɛfagalanw, i n’a fɔ zidovudini (Retrovir®) ani interferon alfa. Nka, ATL suguya bɛɛ tɛ nin banakisɛfagalanw jaabi.
jirisunw falenni . O tɛ se ka kɛ ATL bɛ mɔgɔ bɛɛ la. Nka ni a sera, a bɛ se ka mɔgɔ si janya kosɛbɛ.

HAM/TSP (hakilila bana) bɛ mɔgɔ minnu na, nin fura ninnu bɛ kɛ ka bana taamasiɲɛw kunbɛn ani ka lafiya di u ma:

Interferon alfa.
Aw bɛ funu dɔgɔya ni Kɔritikositɛri ye.
Interféron beta (interféron beta) ye. O bɛ se ka dɛmɛ ka funu dɔgɔya ani ka farikolojidɛsɛ bali.
Aw bɛ farikolojidɛsɛ ni a gɛlɛya dɔgɔya ni Baclofen (Lioresal ®) walima tizanidine ye.
Oksibutini (oxybutynin) min bɛ kɛ ka sugunɛbaralabana furakɛ.

Mun bɛ kɛ ni HTLV-1 bɛ ne la? Yala ne ka kan ka hami wa?

O de ye ko ye min nafa ka bon kosɛbɛ. HTLV-1 banakisɛ bɛ mɔgɔ o mɔgɔ la, o bɛɛ tɛna ATL walima HAM/TSP sɔrɔ. Tiɲɛ na, banakisɛ bɛ mɔgɔ minnu na, olu fanba bɛ se ka ɲɛnamaya kɛ cogo la min bɛ bɛn nin bana jugu ninnu ma.

Nka, ni o bana ninnu bɛ i la, o jateminɛ bɛ bɔ i ka suguya la. ATL suguya sisilen walima a basigilen bɛ mɔgɔ minnu na, olu ka ɲɛtaa bɛ se ka kɛ ka ɲɛ ka tɛmɛ suguya wɛrɛw kan. Hali ni HAM/TSP ka teli ka juguya waati tɛmɛnen kɔfɛ, aw bɛ se ka ɲɛnamaya kɛ san tan caman kɔnɔ bana sɛgɛsɛgɛli kɔfɛ.

Ne bɛ se ka n yɛrɛ tanga nin HTLV-1 banakisɛ in ma cogo di? Yala fɛɛrɛ dɔw bɛ yen minnu bɛ se ka a kunbɛn wa?

Ɔwɔ, fɛn dɔw bɛ yen an bɛ se ka minnu kɛ walasa ka HTLV-1 banakisɛ jɛnsɛnni bali.

Ni aw ye joli ni farikolo yɔrɔw sɛgɛsɛgɛ minnu dira ni HTLV-1 ye, o bɛ se ka dɛmɛ don ka banakisɛ in jɛnsɛnni bali.
Aw bɛ se ka nin fɛn ninnu kɛ walasa ka dɔ bɔ aw yɛrɛ ka farati la:
Aw bɛ aw yɛrɛ tanga furaw pikiri kɛli ma ni furasɛbɛn tɛ aw bolo.
Aw kana pikirijikɛlan kelenw kɛ kokura walima ka u tila ni mɔgɔ wɛrɛw ye.
Aw ye aw yɛrɛ tanga cɛnimusoya ma min tɛ aw tanga. Aw bɛ latex kapɔti kɛ tuma bɛɛ kafoɲɔgɔnya suguya o suguya (musoya, kɔnɔbara, walima da la).
Ni a sɛgɛsɛgɛra ko HTLV-1 bɛ aw la, aw bɛ aw yɛrɛ tanga sin dili ma ani joli dili ma. Ni HTLV-1 bɛ aw la ani ni aw b’a fɛ ka sin di den ma, aw bɛ ladilikan ɲini dɔgɔtɔrɔ fɛ min bɛ HTLV-1 ko dɔn. Ni aw bɛ sinji bɔ ka a bila nɛnɛ na, ka sɔrɔ k’a funu, o bɛ se ka dɔ bɔ banakisɛ in tali la den na, nka a nafa ka bon aw ka dɔgɔtɔrɔ ka ladilikan ɲini sani aw ka o kɛ.

HTLV ɲuman kɔrɔ ye mun ye?

Ni aw ye HTLV sɔrɔ, o kɔrɔ ye ko HTLV-1 walima HTLV suguya wɛrɛ bɛ aw fari la. O kɔrɔ tɛ ko i bɛna ATL walima HAM/TSP yiriwa sisan. Ni HTLV-1 bɛ aw la, fɛɛrɛ dɔw bɛ yen aw bɛ se ka minnu kɛ walasa ka banakisɛ in jɛnsɛn mɔgɔ wɛrɛw la (i n’a fɔ sin dili ma, ka aw yɛrɛ tanga cɛnimusoya ma min tɛ mɔgɔ tanga).

Farati bɛ nin HTLV in na cogo di?

HTLV banakisɛ, ni a kelen ta, a ka ca a la, farati tɛ a la, wa a tɛ a taamasiɲɛw lase mɔgɔ ma. Nka, a nafa ka bon ka a dɔn, barisa HTLV-1 bɛ se ka kansɛri, hakilibana, walima funubana bila mɔgɔ la tuma dɔw la.

Tuma jumɛn na ne ka kan ka taa dɔgɔtɔrɔso la?

Ni ɲininkali bɛ aw fɛ HTLV-1 sɛgɛsɛgɛli ko la, walima ni HTLV-1 bɛ aw la ani ni aw b’a fɛ k’a dɔn aw ka kan ka fɛɛrɛ minnu tigɛ, aw ye aw jija ka kuma dɔgɔtɔrɔ fɛ. A nafa ka bon kɛrɛnkɛrɛnnenya la ka o dɔn ni aw sigilen bɛ yɔrɔ la, HTLV-1 ka ca yɔrɔ min na.

A laban na, fɛn minnu ka kan ka to an hakili la

Okey, donc an ye kuma caman fɔ HTLV-1' kan, tiɲɛ tɛ? Aw k’aw hakili to a la ko hali ni nin ye banakisɛ ye min bɛ sɔrɔ diɲɛ fan bɛɛ la, a man ca yɔrɔ caman na. Nin bana in bɛ mɔgɔ minnu na, olu kɛmɛsarada la, mɔgɔ damadɔ dɔrɔn de bɛ bana jugumanba sɔrɔ.

Min nafa ka bon kosɛbɛ, o ye, aw kana aw hakili ɲagami ni aw ye HTLV-1 sɔrɔ.Mɔgɔ fanba bɛ se ka ɲɛnamaya kɛ kɛnɛya la k’a sɔrɔ taamasiɲɛ foyi tɛ u la. Nka, ni aw ye nin banakisɛ in dɔn, a jɛnsɛncogo, ani a kunbɛncogo, o bɛ se ka aw yɛrɛ tanga ani aw lamini mɔgɔw tanga.

Ni ɲininkali wɛrɛw bɛ aw fɛ o ko la, aw kana siga ka aw ka denbaya dɔgɔtɔrɔ walima dɔgɔtɔrɔ dɔ ɲininka min bɛ o ko dɔn. Aw ka to kɛnɛya la!