Yala tansiyɔn jiginni bɛ i la , walima “ tansiyɔn ” i n’a fɔ an bɛɛ b’a dɔn cogo min na wa? N’a sɔrɔ aw bɛ fura kelen, fila walima fura caman ta minnu sɛbɛnna aw ka dɔgɔtɔrɔ fɛ. Nka, yala a ka gɛlɛn i ma ka i ka tansiyɔn kunbɛn hali ni i ye fura caman ta wa? N’o don, o kun bɛ se ka kɛ fɛn ye min ka teli ka miiri bɛɛ la. Bi an bɛna kuma furakɛli cogoya kɛrɛnkɛrɛnnen dɔ kan min bɛ se ka tansiyɔn jiginni bila mɔgɔ la min tɛ se ka kunbɛn nɔgɔya la furaw fɛ. O ye Hyperaldosteronisme ye. Hali n’a tɔgɔ ka gɛlɛn dɔɔnin, an k’a Faamu nɔgɔya la kosɛbɛ.
Hyperaldosteronisme ye mun ye?
N’an y’a fɔ cogo nɔgɔman na, Hyperaldosteronisme (Hyperaldosteronisme) ye "Aldosterone" ɔrimɔni caman bɔli ye an fari la surɔfiyen fɛ.
Sisan, n’a sɔrɔ i bɛ miiri, nin surɔfiyen glandew ye mun ye ? Nin aldosterone hormone in ye mun ye?
Miiri k’a filɛ, sugunɛ fila sanfɛ an fari la, glande fitini fila bɛ yen, i n’a fɔ fini misɛnnin fila. An bɛ o de Weele ko surɔfiyen. Olu ye an ka endocrine system yɔrɔ nafamaba ye. O gland fitini fila ninnu bɛ ɔrimɔni suguya caman dilan minnu nafa ka bon an farikolo ka don o don baaraw la.
ɔrimɔni kɛrɛnkɛrɛnnen dɔ min bɛ bɔ o glandew fɛ , o bɛ wele ko aldosterone . nin ɔrimɔni in baara kunba ye ka an ka tansiyɔn labɛn . A b’o kɛ ni natiri ni potasiyɔmu hakɛ kɔlɔsili ye an joli la. O ɔrimɔni bɛ baara kɛ an farikolo la i n’a fɔ sirako polisikɛla min bɛ sirako kɔlɔsi sira kan.
O la, ni Hyperaldosteronisme (Hyperaldosteronisme) ye, min bɛ kɛ, o ye ko nin aldosterone hormone in bɛ bɔ ka tɛmɛ. O kɔ, soja hakɛ bɛ caya an fari la ani potasiyɔmu hakɛ bɛ dɔgɔya. O laban ye tansiyɔn jiginni ye (Tansiyɔn jiginni) ani potasiyɔmu hakɛ dɔgɔyali joli la (Hypokalemia) .
O suguba fla bɛ yen.
Dɔgɔtɔrɔw bɛ nin bana in tila ka kɛ suguyaba fila ye, ka kɛɲɛ ni a sababu ye.
1. Hyperaldosteronisme (banakisɛfagalan) fɔlɔ :O fana bɛ Weele ko "Conn ka bana". O bɛ sɔrɔ gɛlɛya dɔ fɛ sugunɛbaralabana yɛrɛ la, o min b’a to u bɛ aldosterone ɔrimɔni caman bɔ. O sababu bɛ sɔrɔ glande yɛrɛ kɔnɔ.
2. Hyperaldosteronisme secondaire : Yan, gɛlɛya tɛ sugunɛbilenni na. Nka ka da gɛlɛya dɔ kan farikolo yɔrɔ wɛrɛw la, sugunɛbaralabana bɛ lawuli o jaabi la ani ka aldosterone caman bɔ.
Nin bana in bɛ jɔn de minɛ kosɛbɛ?
A ka ca a la nin bana in bɛ mɔgɔ minɛ minnu si bɛ san 30 ni san 50 cɛ.Sɛgɛsɛgɛliw y’a jira fana ko nin bana in ka ca dɔɔni musow la ka tɛmɛ cɛw kan.
Kalan dɔw y’a jira ko tansiyɔn jiginni bɛ mɔgɔ minnu na, olu 5% ni 10% cɛ, olu bɛ se ka kɛ ni hyperaldosteronisme fɔlɔ ye. Fɛn dɔnbagaw dalen b’a la ko tansiyɔn jiginni fura tali bɛ mɔgɔ minnu na, olu hakɛ bɛ se ka kɛ 25% ye.
O taamasiɲɛw ye mun ye?
Tuma dɔw la, ni bana in man jugu kosɛbɛ, a bɛ se ka kɛ a taamasiɲɛ si tɛ a la fewu. Nka, bana taamasiɲɛw bɛ mɔgɔ caman na.
Taamasiɲɛba min ka teli ka ye nin bana in na, o ye tansiyɔn jiginni ye (Tansiyɔn jiginni) , kɛrɛnkɛrɛnnenya la tansiyɔn jiginni min kunbɛnni ka gɛlɛn hali ni fura caman kɛra.
A taamasiɲɛ wɛrɛw bɛ sɔrɔ fɛn fila de fɛ: tansiyɔn jiginni ani potasiyɔmu hakɛ dɔgɔyali joli la (Hypokalemia). An ka nin taamasiɲɛ ninnu faranfasi ka jɛya.
| Kun | Taamasiɲɛ minnu bɛ se ka kɛ |
|---|---|
| Tansiyɔn jiginni taamasiɲɛw |
|
| Potassium dɔgɔyali taamasiɲɛw joli la |
|
I hakili to a la ko nin jogo ninnu bɛɛ tɛ bɛɛ la. Mɔgɔ dɔw bɛ se ka kɛ u kelen walima fila dɔrɔn de ye.
Mun na nin bana in bɛ kɛ ni Hyperaldosteronisme ye?
I n’a fɔ an y’a ɲɛfɔ cogo min na ka tɛmɛ, o kunw tɛ kelen ye ka kɛɲɛ ni suguyaba fila ye.
Hyperaldosteronisme (banakisɛfagalan fɔlɔ) sababuw
Gɛlɛya min bɛ yan, o bɛ sɔrɔ surɔfiyen yɛrɛ de la.
- A sababu ka ca : A ka ca a la, o bɛ sɔrɔ kuru dɔ fɛ min tɛ kansɛri ye (adrénale adenome) min bɛ sɔrɔ surɔfiyen gland kɔnɔ. Nin tɛ kansɛri ye, o la, hami foyi tɛ yen. O kuru in bɛ ɔrimɔni aldosterone caman bɔ.
- Sababu wɛrɛ minnu man teli ka sɔrɔ:
- Surɔfiyen gland kelen dɔrɔn bonya (surénaux hyperplasie unique).
- Aldosterone sɔrɔli kansɛribana dɔ fɛ (kansɛri adrénocorticale) (o man ca kosɛbɛ).
- Bana min bɛ sɔrɔ jamu fɛ, min bɛ tɛmɛ mɔgɔw fɛ mɔgɔw fɛ (Familial hyperaldosteronism).
Hyperaldosteronisme filanan sababuw
Yan, sugunɛbaralabana bɛ kɛnɛya. Nka u bɛ lawuli kun wɛrɛ de kama. a kunba ye joli sɔrɔli dɔgɔyali ye sugunɛw la .
Walasa k’o faamu, an ka kan ka dɔɔni dɔn an farikolo kɔnɔ sigida dɔ kan min ka di kosɛbɛ, min bɛ tansiyɔn kɔlɔsi. A bɛ fɔ a ma ko Renin-Angiotensin-Aldosterone System .
Aw ye nin jate i n’a fɔ cakɛda wale:
1. Ni an ka tansiyɔn jiginna walima ni soja hakɛ jiginna an joli la, an ka sugunɛw b’o dɔn.
2. O kɔ, sugunɛ bɛ anzimu dɔ bɔ joli la min bɛ wele ko "renin".
3. Nin renin in bɛ farikolojɔlifɛn dɔ sɛmɛntiya min bɛ wele ko "Angiotensinogen", o min bɛ sɔrɔ sugunɛ fɛ, ka kɛ "Angiotensin I" ye.
4. O kɔfɛ, nin angiotensin I in bɛ kɛ “Angiotensin II” ye.
5. A laban na, o angiotensin II in de bɛ tansiyɔn bonya ni joli siraw gɛlɛyali ye ani ka sugunɛbilenniw lawuli walasa u ka aldosterone dilan.
Sisan, hyperaldosteronisme filanan na, min bɛ kɛ, o ye ko furakɛli cogoya dɔw kosɔn, joli min bɛ taa sugunɛ na, o bɛ dɔgɔya. O kɔ, sugunɛw bɛ fili ka miiri ko degun min bɛ farikolo la, o ka dɔgɔn. O la, sugunɛw bɛ dɛmɛ wele ani o cakɛda bɛ daminɛ. O de kosɔn, u bɛ ɔrimɔni aldosterone caman dilan, k’a sɔrɔ tiɲɛ na, mago tɛ a la.
Bana minnu bɛ joli bɔli dɔgɔya sugunɛ na ani ka kɛ sababu ye ka sugunɛbilenni filanan bila mɔgɔ la:
- Sugunɛbilenni min bɛ sugunɛbaralabana bali.
- Bana minnu bɛ kɛ sababu ye ka ji dalajɛ farikolo la, i n’a fɔ dusukun tantanni.
- Sugunɛbilenni (cirrhose) bɛ sɔrɔ sugunɛ na.
- Nephrotique syndrome, o ye sugunɛbana ye.
Dɔgɔtɔrɔ bɛ o bana in sɛgɛsɛgɛ cogo di?
Ni aw ye aw ka bana taamasiɲɛw fɔ aw ka dɔgɔtɔrɔ ye, kɛrɛnkɛrɛnnenya la tansiyɔn jiginni min tɛ furaw kunbɛn, a bɛ se ka sigasiga nin bana in na. O kɔ, u bɛ se ka yamaruya di sɛgɛsɛgɛli caman kɛ walasa ka o dafa.
1. Joli sɛgɛsɛgɛliw:
- Ni joli-sira-funu-minɛn min bɛ kɛ tuma bɛɛ, o y’a jira ko natiri hakɛ cayalenba dɔɔni (Hypernatremie) ani potasiyɔmu hakɛ dɔgɔyali (Hypokalemia) , siga bɛ bonya.
- O kɔfɛ, joli sɛgɛsɛgɛli kɛrɛnkɛrɛnnen fila bɛ yen minnu bɛ se ka kɛ ka nin bana in dɔn: Renin hakɛ min bɛ sɔrɔ joli la (PRC) walima Renin ka baarakɛcogo joli la (PRA) .
- Ni Hyperaldosteronisme Primaire bɛ aw la, aw ka renin hakɛ (PRC ni PRA) bɛna dɔgɔya ka tɛmɛ a cogo kɔrɔ kan.
- Ni hyperaldosteronisme filanan bɛ aw la, aw ka renin hakɛ bɛna caya ka tɛmɛ a cogo kɔrɔ kan.
2. Aldosterone (Aldosterone) balili sɛgɛsɛgɛli:
- Nin sɛgɛsɛgɛli in ye ka soja (kɔgɔ) wɛrɛ di aw ma waati dɔ kɔnɔ. A bɛ se ka kɛ furaji ye aw bɛ min ta da la walima aw bɛ kɔgɔji min di jolisira la.
- O kɔ, aw bɛ aw ka sugunɛ lajɛ lɛri 24 kɔnɔ ka sɔrɔ ka aldosterone hakɛ jateminɛ o sugunɛ na.
- Mɔgɔ kɛnɛman na, soja dunni tɛmɛnen bɛ dɔ bɔ farikolo ka aldosterone bɔli la. Nka, aldosteronizi (hyperaldosteronisme) bɛ mɔgɔ min na, o tɛ kɛ.
3. Jala sɛgɛsɛgɛliw:
- Ni joli sɛgɛsɛgɛliw y’a jira ko sɔgɔsɔgɔninjɛ fɔlɔ bɛ aw la, aw ka dɔgɔtɔrɔ bɛna yamaruya di ka sɛgɛsɛgɛli kɛ i n’a fɔ CT scan (Computer Tomography scan) walasa ka a sababu dɔn. O bɛ se ka a lajɛ ni kuru dɔ bɛ sugunɛbara la.
O furakɛcogo jumɛnw bɛ yen?
Furakɛli bɛ bɔ bana in sababu la. Nka, a kuntilenna kunba ye ka i ka tansiyɔn kunbɛn.
- Ni hyperaldosteronisme fɔlɔ min bɛ sɔrɔ tumu fɛ:
Tuma caman na, dɔgɔtɔrɔw b’a fɔ ko opereli ka kuru ni a ni a ɲɔgɔnna gland bɔ.. Mɔgɔ fanba ka tansiyɔn ni potasiyɔmu hakɛ bɛ segin a cogo kɔrɔ la opereli in kɔfɛ. Nka, tansiyɔn jiginni bɛ se ka to mɔgɔ dɔw la opereli kɔfɛ, wa u bɛna a ɲini ka taa a fɛ ka furaw ta.
- Ni sababu wɛrɛw ani aldosteronisme filanan ye:
O cogo la, furakɛli bɛ kɛ ni furaw ye . Ani fana, ni bana filanan don, a nafa ka bon ka bana basigilen furakɛ (misali la dusukunnabana).
Fura minnu bɛ kɛ ka caya o baara kama, olu dɔw ye:
- Spironolaktɔni (Spironolactone – Aldactone®) .
- Eplerenone (Eplerenone – Inspra®) ye .
- Amiloridi (Amiloride – Midamor®) ye .
Nin fura ninnu, kɛrɛnkɛrɛnnenya la minnu bɛ aldosterone baara bali, i n’a fɔ Spironolactone, olu bɛ se ka kɔlɔlɔ dɔw lase cɛw ma ni u kɛra ka mɛn. Misali la, cɛya ni sinji bonya (gynecomastie). Ni aw ye nin taamasiɲɛ ninnu dɔ ye, aw kana siga ka kuma aw ka dɔgɔtɔrɔ fɛ o ko la.
Mun bɛna kɛ furakɛli kɔfɛ? Ani, gɛlɛya jumɛnw bɛ o la?
Nin bana in ɲɛfɔli, o kɔrɔ ye ko a cogoya nata, o bɛ bɔ a sababu de la.
A ka ca a la , aldosteronizi fɔlɔ bɛ muɲu kosɛbɛ ni a sɔrɔla joona ani ni a furakɛra ka ɲɛ . Hyperaldosteronisme filanan na, a kɔlɔlɔ bɛ bɔ ni bana basigilen bɛ se ka kunbɛn.
Gɛlɛya kunbaba minnu bɛ se ka sɔrɔ nin bana in na, olu bɛ sɔrɔ tansiyɔn jiginni fɛ min tɛ se ka kunbɛn waati jan kɔnɔ. Olu ye gɛlɛyabaw ye minnu bɛ tali kɛ dusukun ni jolisiraw la.
| Gɛlɛya kunbaba minnu bɛ se ka sɔrɔ |
|---|
| Fibrillation atriale (dusukun tantanni min tɛ bɛn) . |
| Dusukun kiniyanfan fɛ ɲɛgɛnɛsiralabanaw (dusukun kiniyanfan fɛbara bonya) . |
| Dusukun tantanni |
| Kuru bɔ |
O la, a nafa ka bon kosɛbɛ ka tansiyɔn kunbɛn ka ɲɛ.
Yala o ko bɛ se ka bali wa?
A ka ca a la, foyi tɛ an bolo ka nin bana in bali. Sabula a bɛ sɔrɔ fɛn caman Changements (Yɛlɛma) fɛ minnu bɛ kɛ an farikolo kɔnɔ. Nka min ka fisa, o ye ko ni a sɛgɛsɛgɛra ka ban, a bɛ se ka furakɛ ani ka gɛlɛyaw bali.
Take-Home cikan
- Ni gɛlɛya bɛ aw la ka aw ka tansiyɔn kunbɛn hali ni aw bɛ fura caman ta, aw ye aw jija ka o fɔ aw ka dɔgɔtɔrɔ ye .
- Hyperaldosteronisme ye bana ye min bɛ sɔrɔ aldosterone hormone bɔli kojugu fɛ.
- O bɛ se ka kɛ fɔlɔ ye (gɛlɛya min bɛ ɲɛgɛnɛsira yɛrɛ la) walima filanan (bana wɛrɛ sababu fɛ).
- Nin bana in bɛ se ka dɔn ka ɲɛ ni joli sɛgɛsɛgɛli kɛrɛnkɛrɛnnenw ni sɛgɛsɛgɛliw ye.
- Ka kɛɲɛ ni a sababu ye, a bɛ se ka furakɛ ka ɲɛ ni opereli walima fura ye.
- A yɔrɔ min ka fisa, o ye ko nin ye bana ye min bɛ se ka furakɛ. O la, ni siga dɔ bɛ aw la nin ko in na, a tɛ tɛmɛn abada ka dɔgɔtɔrɔ ka ladilikan ɲini.
Hyperaldosteronisme, aldosterone, surrénale glandes, Conn’s syndrome, tansiyɔn jiginni, tansiyɔn jiginni, tansiyɔn, potasiyɔmu, soja, sugunɛ, ɔrimɔni
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