Yala tulumafɛnw bɛ i farikolo yɔrɔw la wa? An ka kunnafoni sɔrɔ Lipodystrophie kan!

Yala aw delila ka tulu bɔli barikama ye aw farikolo yɔrɔ dɔw la, walima ka tulu caya yɔrɔ wɛrɛw la aw t’a fɛ wa? O bɛ se ka kɛ tuma dɔw la fɛn ye min tɛ se ka miiri. Bi an bɛna kuma nin cogoya yɛrɛ de kan. Furakɛcogo la, o bɛ wele ko Lipodystrophie . Aw kana aw hakili ɲagami, hali ni o tɔgɔ bɛ se ka kɛ kabako ye, an ka kuma o kan cogo nɔgɔman na.

Lipodystrophie ye mun ye?

N’an y’a fɔ cogo nɔgɔman na, Lipodystrophy ye tulumafɛnw bɔnɛni ye pewu walima a yɔrɔ dɔ, an bɛ min wele tuma caman na ko “tulu”, yɔrɔ dɔw la, walima tulumafɛnw dalajɛli farikolo yɔrɔ caman na cogo la min tɛ bɛn.

Miiri k’a filɛ ko i bɛ ka i girinya dɔgɔya i farikolo yɔrɔ dɔw la, i n’a fɔ i bolokɔniw ni i senw, ka sɔrɔ ka tulumafɛnw caya yɔrɔ dɔw la i n’a fɔ i ɲɛda ni i kɔ. O de bɛ kɛ Lipodystrophie la. Nin bana suguya wɛrɛw bɛ yen, dɔw bɛ sɔrɔ jamu fɛ (i n’a fɔ an bangera ni fɛn min ye), dɔw bɛ sɔrɔ kɔfɛ furakɛli cogoya wɛrɛw sababu fɛ. A suguya kelen kelen bɛɛ bɛ mɔgɔw minɛ cogo wɛrɛ la, wa a taamasiɲɛw tɛ kelen ye.

Mun na tulu (tuma) nafa ka bon kosɛbɛ an farikolo la?

Sisan, i bɛ se ka miiri ko: “Ni i tulu ka dɔgɔn, o ka fisa.” Nka tiɲɛ yɛrɛ la, tulumafɛnw bɛ baara nafama caman kɛ an farikolo la. Aw ye a lajɛ:

• Fanga marali : O tulumafɛnw de la, an bɛ kalori wɛrɛ minnu sɔrɔ an bɛ dumuni minnu dun, olu bɛ mara i n’a fɔ fanga.
• Lakanali: A bɛ lakanani di an farikolo yɔrɔ suguya caman ma i n’a fɔ kuran.
• Sumaya sabatili: A bɛ farikolo funteni mara ani k’an tanga nɛnɛ ma.
• Ɔrimɔni bɔli : Ɔrimɔni nafama caman, i n’a fɔ Leptin, olu bɛ bɔ ka bɔ joli la.
• Funu kunbɛnni : A bɛ dɛmɛ fana ka funu kunbɛn farikolo la.

O la, ni o tulumafɛn in tununna walima ni a bilala cogo la min tɛ a cogo la ka a sababu kɛ tulumafɛnw ye, an ɲɛda tɛ Changé dɔrɔn, nka farikoloɲɛnajɛ baara nafamaw fana bɛ tiɲɛ farikolo la. Lipodystrophie bɛ mɔgɔ caman na, farati bɛ olu la ka banaw sɔrɔ i n’a fɔ sukarodunbana ani joli la kolosinsinnan hakɛ tɛ kelen ye.

Yala farikolojidɛsɛ suguya dɔw bɛ yen wa?

Ɔwɔ, Lipodystrophie bɛ se ka tila suguya fila ye: jamu ni sɔrɔlen.

Lipodystrophie génétique suguyaw

Olu ye ciyɛn ye, o kɔrɔ ye ko suguya minnu bɛ sɔrɔ ka da fɛn caman sɛgɛsɛgɛli kan.

• Lipodystrophie général congénitale (CGL): Nin ye Berardinelli-Seip ka bana ye.A bɛ fɔ fana ko. Nin ye bana ye min man ca kosɛbɛ. O la, farikolo tulu bɛ ɲini ka ban pewu walima a fanba. O bɛ sɔrɔ jamu nafama dɔ fɛ min bɛ sɔrɔ bange waati. A ka ca a la, nin bana in bɛ se ka sɔrɔ a si san fɔlɔ kɔnɔ.
• Denbaya kɔnɔ farikolojidɛsɛ (FPLD): Nin fana ye bana ye min bɛ sɔrɔ jamu fɛ. Nka, a ka ca a la a bɛ sɔrɔ kɔfɛ ɲɛnamaya kɔnɔ. O cogo la, den bɛ tulu bɔ a senw ni a bolokɔniw na kɛrɛnkɛrɛnnenya la, wa a bɛ tulu caman lajɛ a ɲɛda ni a kɔ la.

Lipodystrophie acquise suguyaw

Olu ye suguw ye minnu bɛ sɔrɔ an bangenen kɔfɛ ani an ka ɲɛnamaya kɔnɔ kun caman kosɔn.

• Acquired Generalized Lipodystrophy (AGL): A bɛ fɔ fana ko Lawrence syndrome , o bana in bɛ tulu bɔli bila mɔgɔ la, a ka ca a la ɲɛda, kɔ, bolokɔniw ani senw na. O tulumafɛnw bɔli bɛ se ka kɛ joona, dɔgɔkun damadɔ kɔnɔ, walima dɔɔni dɔɔni kalo walima san caman kɔnɔ. A ka ca a la a bɛ daminɛ denmisɛnya walima funankɛya la, nka a bɛ se ka kɛ san o san. AGL sababu damadɔ bɛ se ka sɔrɔ.
• Acquired Partial Lipodystrophy (APL): A bɛ fɔ fana ko Barraquer-Simons syndrome , o bana in bɛ kɛ sababu ye ka tulu bɔ dɔɔni dɔɔni ɲɛda, kɔ, bolokɔniw ani disi la denmisɛnya waati. Mɔgɔ dɔw fana bɛ se ka tuluma kojugu yɔrɔw la i n’a fɔ kɔnɔbara, senw ani kɔkiliw. APL ka teli ka kɛ ni farikolo tangalanw ka banaw ye .
• Furakɛli min bɛ kɛ ni banakisɛfagalanw ye (HAART)-induite lipodystrophy (LD-HIV): Nin farikolojidɛsɛ suguya bɛ kɛ mɔgɔ minnu na , hadamaden farikolo tangalan banakisɛ (VIH) bɛ minnu na, u kɛlen kɔ ka furakɛli kɛ ni banakisɛfagalanw ye minnu bɛ baara kɛ kosɛbɛ (HAART) minnu bɛ sidabanakisɛ 1 poroteyizi balilanw sɔrɔ Nin bana in sɔrɔli bɛ bɔ furakɛli fanga ni a kuntaala la. LD-HIV bɛ mɔgɔ minnu na, olu ka teli ka tulu bɔ dɔɔni dɔɔni u bolow, u senw ani u ɲɛda la. Mɔgɔ dɔw fana bɛ se ka tulu tɛmɛnen sɔrɔ u ɲɛda la, u kɔ la, u kɔ sanfɛla la ani u cɛmancɛ la.
• Lipodystrophie localisée : O ye ni tulu bɛ bɔ farikolo yɔrɔ fitinin dɔrɔn na. Misali la, nin bana in bɛ se ka sɔrɔ ni furaw (i n’a fɔ inisɔndiya) pikirila yɔrɔ kelen na siɲɛ caman. A bɛ i n’a fɔ dingɛ fitini dɔ, nka a ka ca a la fari min bɛ a kan, o tɛ nɔ bila a la.

Yala Lipodystrophie ni Lipoatrophie ye fɛn kelen ye wa?

Lipodystrophie ye kumasen ye min bɛ fɔ tulu tilatilali cogo la min tɛ bɛn. A ni Lipoatrophy fana bɛ tali kɛ ɲɔgɔn na, o kɔrɔ ye tulu bɔli ye. Dɔnniyakɛla dɔw ni dɔgɔtɔrɔ dɔw bɛ o kumasen fila bɛɛ fɔ walasa ka bana kelen ɲɛfɔ. N’an y’a fɔ cogo nɔgɔman na, Lipoatrophie ye Lipodistrophie kulu fitinin dɔ ye.

Nin bana in bɛ jɔn de minɛ kosɛbɛ? A ka ca cogo di?

Lipodystrophie suguya fanba bɛ daminɛ denmisɛnni na, nka suguya sɔrɔlenw bɛ se ka sɔrɔ balikuw fana na.

N’a ma fɔ HAART-induite lipodystrophy (LD-VIH) , lipodystrophie sɔrɔlen suguya wɛrɛw ka teli ka musow minɛ. Ikomi sidabanakisɛ ka ca cɛw la, LD-HIV fana ka ca cɛw la.

A ka ca a la, farikolojidɛsɛ ka dɔgɔn kosɛbɛ . Nka, farikolojidɛsɛ suguya sɔrɔlenw (ɲɛnamaya bɛɛ kɔnɔ) bɛ ka caya ka a sababu kɛ fura dɔw kɔlɔlɔw ye.

Lipodystrophie bɛ nɔ bila ne farikolo la cogo di?

Lipodystrophie suguya kelen-kelen bɛɛ bɛ farikolo minɛ cogo wɛrɛ la, nka fɛnba fila bɛ yen minnu ka teli ka kɛ: tulumafɛnw bɔnɛni ani leptini ɔrimɔni dɛsɛ.

Fasa bɔnɛni nɔ min bɛ farikolo la

an ka tulumafɛnw bɛ kɛ ni farikolokisɛw ye minnu bɛ wele ko adipocytes . Fasa-banakisɛ kelen-kelen bɛɛ kɔnɔ, tulumafɛnw 90% ɲɔgɔn bɛ sɔrɔ. O tulumafɛnw bɛ tulu (triglycérides) mara. Ni o tulumafɛnw tiɲɛna ka a sababu kɛ tulumafɛnw ye, u tɛ se ka tulumafɛnw mara ka ɲɛ.

Lipodystrophie dɔw la, o tulu bɔnɛnen in bɛ bila an farikolo yɔrɔ wɛrɛw la cogo jugu la, misali la, sugunɛ, kɔnɔbara walima farikolo yɔrɔ dɔw la. O bɛ se ka kɛ sababu ye ka kɛnɛyako gɛlɛyaw lase mɔgɔ ma i n’a fɔ:

• Sugunɛbilenni tuluma / sugunɛbilenni
• Insuline (insuline) tali ni insuline (insuline) hakɛ cayalenba joli la (hyperinsulinemie) .
• Jabɛtibana (Jabɛtibana) .
• Triglycérides hakɛ caya joli la (hypertriglycéridémie) .
• Pankreyasi banakisɛ
• Syndrome métabolique (banakisɛfagalanw) bɛ sɔrɔ
• Koronawirisi bana

Nka aw hakili to a la ko farikolojidɛsɛ bɛ mɔgɔ minnu na, olu bɛɛ tɛna nin bana ninnu sɔrɔ. Dɔw bɛ se ka kɛ cogo nɔgɔman na, ka sɔrɔ dɔw ka jugumanba bɛ se ka kɛ.

Leptini dɛsɛ bɛ se ka nɔ minnu bila farikolo la

Ikomi farikolojidɛsɛ bɛ mɔgɔ minnu na, olu bɛ tulu bɔ u la, u bɛ ɔrimɔni dɔw fana bɔ u la, kɛrɛnkɛrɛnnenya la, ɔrimɔni leptin .

Leptin ye ɔrimɔni ye min bɛ sɔrɔ an ka tulumafɛnw fɛ. A b’an dɛmɛ ka farikolo girinya cogo bɛnnen na waati jan kɔnɔ. Yala i b’a dɔn cogo min na wa? U kɛtɔ k’a to an k’a ye ko an falen don ani k’an ka kɔngɔ kunbɛn. Dɔnniyakɛlaw bɛ ka sɛgɛsɛgɛli kɛ hali bi leptin. U dalen b’a la ko lɛptini bɛ nɔ bila an ka farikoloɲɛnajɛ la , farikolo yɔrɔw baara la, ani farikolo tangacogo baara la.

Lipodystrophie bɛ mɔgɔ minnu na, olu bɛ se ka lɛptini hakɛ dɔgɔya, o bɛ se ka kɛ sababu ye ka kɔngɔ kojugu, ka inisɔndiya sɔrɔ, ani ka kɛnɛya gɛlɛya wɛrɛw lase u ma.

Lipodystrophie taamasiɲɛ jumɛnw bɛ yen?

Ikomi farikolojidɛsɛ suguya caman bɛ yen, a taamasiɲɛw fana ka ca kosɛbɛ.

A taamasiɲɛ min ka teli ka kɛ, o ye tulu bɔli ye min jɛlen don ani min bɛ to sen na farikolo yɔrɔ dɔw la, ka sɔrɔ o waati kelen na, tulu dalajɛli ye farikolo yɔrɔ wɛrɛw la cogo la min tɛ bɛn walima min man ɲi.

Misali la, farikolojidɛsɛbanakisɛ (APL) bɛ mɔgɔ minnu na, olu tulu bɛ bɔ u ɲɛda, u kɔ la, u bolokɔniw na ani u disi la dɔɔni dɔɔni u denmisɛnman. APL bɛ mɔgɔ minnu na, olu dɔw fana bɛ se ka tulumafɛnw sɔrɔ yɔrɔw la i n’a fɔ kɔnɔbara, senw ani kɔkiliw.

Ka kɛɲɛ ni farikolojidɛsɛ suguya ye ani aw si hakɛ, a bɛ se ka kɛ aw tɛna kɛnɛya gɛlɛyaba si kɔlɔsi san caman kɔnɔ. Nka, farikolojidɛsɛ suguya caman bɛ kɛ sababu ye ka joli la kolosinsinnan, triglycérides ani sukaro (glucose) hakɛ caya. Aw ka dɔgɔtɔrɔ bɛ se ka ninnu dɔn ni joli sɛgɛsɛgɛliw ye minnu bɛ kɛ tuma bɛɛ, i n’a fɔ lipid panɛli ani farikolojɔli panɛli basigilen .

Lipodystrophie suguya dɔw, kɛrɛnkɛrɛnnenya la lipodystrophie partielle, olu sɛgɛsɛgɛli bɛ se ka gɛlɛya. O la, a nafa ka bon ka taa dɔgɔtɔrɔso la ni bana taamasiɲɛ kuraw bɛ aw walima aw den na walima ni taamasiɲɛ kɔrɔ dɔ juguyara, a sababu mana kɛ fɛn o fɛn ye.

Lipodystrophie sababuw ye jumɛnw ye?

Lipodystrophie sababuw tɛ kelen ye ka kɛɲɛ ni a kɛra jamu ye walima ni a sɔrɔla.

Lipodystrophie génétique sababuw

Lipodistrophie jamu suguyaw – n’o ye lipodystrophie général congénitale (CGL) ani lipodystrophie partielle familiale (FPLD) – olu bɛ sɔrɔ jamu caman caman cili fɛ .

Yɛlɛma donna jamu fɛ, o ye fɛn ye min bɛ yeli kɛ an ka ADN sinsinni na. An ka ADN sinsinni de bɛ kunnafoni di an ka selilɛriw ma u mago bɛ minnu na walasa k’u ka baara kɛ. O la, ni nin ADN sinsinni yɔrɔ dɔ ma dafa walima ni a tiɲɛna, an bɛ se ka bana dɔ taamasiɲɛw sɔrɔ jamu fɛ.

• Lipodistrophie général congénitale (CGL) sababuw : CGL suguya 1 fo 4 bɛ sɔrɔ fɛn caman cili fɛ AGPAT2, BSCL2, CAV1 , ani CAVIN1 jamu la. O jamu ninnu nafa ka bon tulu maralanw (adipocytes) ka bonya n’u ka baara la an ka tulumafɛnw na. Yɛlɛma minnu bɛ kɛ o jamu ninnu na, olu bɛ nɔ bila farikolo tulumafɛnw jɔcogo n’u baara la. CGL bɛ denmisɛn min na, o bɛ o jeninida caman ciyɛn ta u bangebagaw fɛ. Hali ni bangebaga fila bɛɛ bɛ ni jamu fɛn caman sɛgɛsɛgɛlen kopi kelen ye, a ka c’a la, u tɛ bana taamasiɲɛw jira.
• Denbaya ka farikolojidɛsɛ (FPLD) sababuw : Ni fɛn caman b’a la ka fɛn caman sɛgɛsɛgɛ, o bɛ se ka kɛ sababu ye ka FPLD bila mɔgɔ la. A ka ca ni tɔw bɛɛ ye, o ye LMNA ye.Yɛlɛma donna jɛnɛya dɔ la min bɛ wele ko LMNA. LMNA jamu ni jamu wɛrɛ minnu bɛ FPLD la, olu bɛ tulumafɛnw bila ka tulu mara ani ka farikolojɔlifɛn suguya caman dilan minnu nafa ka bon tulu marali la. Ni fɛn dɔ jiginna o jamu ninnu dɔ la kelen na, o bɛ nɔ jugu bila farikolo tulumafɛnw falenni, u jɔcogo walima u baara la. FPLD banakisɛ fanba bɛ sɔrɔ ciyɛn ta cogo la min bɛ wele ko autosomal dominant pattern . O kɔrɔ ye ko ni jamu fɛn caman sɛgɛsɛgɛlen in kopi kelen bɛ selilu kelen-kelen bɛɛ kɔnɔ, o bɛ se ka bana in bila mɔgɔ la. Tuma dɔw la, FPLD bɛ mɔgɔ min na, o bɛ o fɛn falen in ciyɛn ta u bangebaga dɔ fɛ min bananen don. Tuma wɛrɛw la, u bɛ sɔrɔ fɛn kuraw fɛ minnu bɛ kɛ ka kɛɲɛ ni jamu ye, wa u bɛ se ka kɛ hali ni bana ma sɔrɔ denbaya kɔnɔ mɔgɔ si la fɔlɔ.

Lipodystrophie acquise sababuw

Lipodistrophie acquise bɛ se ka sɔrɔ furaw fɛ, farikolo tangalanw fɛ , walima sababuw fɛ minnu tɛ sɔrɔ . Hali ni jamu basigilen tɛ yen min bɛ se ka kɛ sababu ye ka tulumafɛnw sɔrɔ, ɲininikɛla dɔw dalen b’a la ko mɔgɔ dɔw ka jamu bɛ se ka kɛ sababu ye ka tulumafɛnw sɔrɔ.

• Lipodystrophie général acquise (AGL) sababuw : AGL bɛ se ka sɔrɔ banakisɛ sɔrɔlen kɔfɛ walima farikolo tangalanw ka bana kɔfɛ. Banakisɛ minnu ni AGL bɛ tali kɛ ɲɔgɔn na olu dɔw ye:
• Kɔnɔboli (Kɔnɔboli / varicella) .
• Sumayabana
• Sɔgɔsɔgɔninjɛ (sɔgɔsɔgɔninjɛ) .
• Dipterie (banakisɛfagalan).
• Sɔgɔsɔgɔninjɛ
• Kolotugudaw ka bana
• Mononucléosis (Nukilisi kelen / mono) .

A ma jɛya ko aw bɛna AGL sɔrɔ dɔrɔn ka da a kan nin banakisɛ ninnu bɛ aw la.

Banakisɛfagalanw ka bana minnu bɛ sɔrɔ AGL fɛ, olu dɔw ye:

• Sɔgɔsɔgɔninjɛ min bɛ sɔrɔ farikolo tangalanw fɛ
• Sugunɛbilenni min bɛ sɔrɔ farikolo tangacogo fɛ
• Denmisɛnw ka farikolojidɛsɛ
• Ɲɛgɛnɛsiraw ka bana
• Sjogren ka bana dɔ
• Jolidɛsɛ min bɛ sɔrɔ farikolo tangalanw fɛ

Ni nin farikolo tangalanw bɛ aw la, a tɛ se ka fɔ ko aw bɛna AGL sɔrɔ sisan.

A ka ca a la, AGL sababu tɛ se ka dɔn (idiopathique).

• Lipodystrophie partielle acquise (APL) sababuw : Dɔnniyakɛlaw dalen b’a la ko APL bɛ sɔrɔ an farikolo tangalanw fɛ minnu bɛ fili ka tulumafɛnw tiɲɛ. APL bɛ mɔgɔ minnu na, olu ka ca ni 80% ye , Complement 3 bɛ u joli la.Protéine (banakisɛfagalan) dɔ hakɛ ka dɔgɔn min bɛ wele ko complement facteur. A ka c’a la, o farikolojɔli dumuni in sen bɛ an farikolo tangacogo jaabi la. APL bɛ mɔgɔ minnu na, a ka ca a la, farikolo tangalan dɔ bɛ u joli la min bɛ wele ko complement 3-nephritic factor . Autoanticorps ye farikolojɔlan ye min bɛ farikolo tangalan na, min bɛ fili ka bin farikolo yɔrɔ kɛnɛmanw kan ani ka u tiɲɛ.

• Furakɛcogo min bɛ kɛ ni banakisɛfagalanw ye (HAART) min bɛ sɔrɔ farikolojidɛsɛ fɛ (LD-HIV): Dɔnniyakɛlaw ma da a la hali bi mun na HAART, sidabanakisɛ 1 protéase inhibiteurs bɛ min na, o bɛ farikolojidɛsɛ bila mɔgɔ la.

Kibaru duman ye ko mɔgɔ fanba minnu bɛ sidabana furakɛli daminɛ sisan, olu man kan ka hami kojugu farikolojidɛsɛ la, barisa sidabana fura kuraw bɛ a to bana in ka teli ka kɛ.

Aw bɛ a dɔn cogo di ni farikolojidɛsɛ bɛ aw la?

Ni farikolojidɛsɛ taamasiɲɛw bɛ aw la, aw ka dɔgɔtɔrɔ bɛna farikololajɛ kɛ, ka aw ka furakɛli tariku ni aw ka denbaya ka furakɛli tariku ɲininka, o kɔ aw bɛ sɛgɛsɛgɛli dɔw yamaruya walasa ka bana in sɛgɛsɛgɛ ani ka a dɔn ni sababu wɛrɛw bɛ aw ka bana taamasiɲɛw la.

Sɛgɛsɛgɛli jumɛnw bɛ kɛ walasa ka farikolojidɛsɛbana sɛgɛsɛgɛ?

Aw ka dɔgɔtɔrɔ bɛ se ka yamaruya di aw ma ka sɛgɛsɛgɛli caman kɛ walasa ka farikolojidɛsɛ dɔn ani/walima ka a dɔn ni sababu wɛrɛw bɛ aw ka bana taamasiɲɛw la. Olu dɔw ye:

• Farikolo bɛɛ lajɛlen ka MRI (Magnetic Resonance Imaging) sɛgɛsɛgɛli: MRI bɛ baara kɛ ni magɛnni belebele ye, arajo fiɲɛw ani ɔridinatɛri ye walasa ka farikolo yɔrɔw ni fɛn wɛrɛw ja caman dilan i farikolo kɔnɔ. Aw ka dɔgɔtɔrɔ bɛ se ka nin sɛgɛsɛgɛli in yamaruya walasa ka tulu hakɛ ni a tilatilali jateminɛ aw fari la.
• Panneau métabolique complète : Nin ye joli sɛgɛsɛgɛli ye min bɛ fɛn suguya 14 suman i joli la. A bɛ kunnafoni nafamaw di i farikolo ka kemikaliya balansi ni a ka farikoloɲɛnajɛ kɛcogo kan. Dɔgɔtɔrɔ bɛna aw joli sukaro (glucose) hakɛ ni sugunɛbilenniw lajɛ kɛrɛnkɛrɛnnenya la .
• Lipidi Panɛli : Nin fana ye joli sɛgɛsɛgɛli ye. A bɛ tulumafɛnw hakɛ jateminɛ min bɛ wele ko tulumafɛnw i joli la. A ka ca a la, nin sɛgɛsɛgɛli in bɛ kɛ ni kolosinsinnan sumanikɛlan naani ye ani triglycérides sumanikɛlan ye. A ka ca a la, farikolojidɛsɛ bɛ kɛ sababu ye ka kolosinsinnan hakɛ tɛ kelen ye.
• Leptin sɛgɛsɛgɛli : O bɛ lɛptini hakɛ jateminɛ aw joli la. Ni farikolojidɛsɛ bɛ aw la ani ni aw ka lɛptini hakɛ ka dɔgɔn ka tɛmɛ a cogo kɔrɔ kan, o bɛ se ka hakilina dɔw di aw ma aw farikolo bɛna a jaabi cogo min na lɛptini sinsinni furakɛli la.
• Jɛnkulu sɛgɛsɛgɛli : Ni dɔgɔtɔrɔ bɛ sigasiga ko Lipodystrophie (banakisɛfagalan) suguya dɔ bɛ aw la min bɛ sɔrɔ ciyɛn fɛ (jɛnɛya fɛ), u bɛ se ka jamu sɛgɛsɛgɛli fɔ aw ye walasa ka bana in sɛgɛsɛgɛ.
• Sugunɛbilenni (biopsie) :O ye ka sugunɛbaralabana dɔ bɔ opereli fɛ ka a sɛgɛsɛgɛ ni mikroskɔpu ye. Aw ka dɔgɔtɔrɔ bɛ se ka nin sɛgɛsɛgɛli in yamaruya walasa ka a dɔn ni tulumafɛnw ye aw ka sugunɛw minɛ.

Farikoloɲɛnajɛ furakɛcogo jumɛnw bɛ yen?

Lipodystrophie furakɛli ni a furakɛcogo bɛ bɔ suguya kɛrɛnkɛrɛnnen na min bɛ aw la, ani ni bana wɛrɛw bɛ aw la minnu bɛ tali kɛ a la, i n’a fɔ sukarodunbana walima kolosinsinnan hakɛ min tɛ a cogo la.

Furakɛli minnu bɛ kɛ ka caya farikolojidɛsɛ furakɛli la, olu ye:

• Leptini nɔnabila fura: Aw ka dɔgɔtɔrɔ bɛ se ka lɛptini ɔrimɔni suguya dɔ sɛbɛn aw ye min bɛ wele ko metreleptin . Lipodystrophie bɛ mɔgɔ minnu na, a ka ca a la, lɛptini dɛsɛ bɛ olu la. Nin ɔrimɔni in bɛ farikolo ka farikoloɲɛnajɛ kɛcogo ɲɛnabɔ ani a bɛ se ka kolosinsinnan ni triglycérides hakɛ fana dɔgɔya.
• Sukarodunbana ni inisɔndiya furakɛli : Ni inisɔndiya ni/walima sukarodunbana bɛ aw la ka a sababu kɛ tulumafɛnw ye, aw ka dɔgɔtɔrɔ bɛ se ka furaw di aw ma minnu bɛ ta da la i n’a fɔ piyoglitazone, metformin, sulfonylureas , walima thiazolidinediones walasa k’a furakɛ. Lipodystrophie bɛ mɔgɔ minnu na, olu dɔw fana ka kan ka insuline synthétique ta walasa ka u ka sukarodunbana furakɛ. aw bɛ se fana ka to ka aw ka sukaro hakɛ lajɛ so kɔnɔ ni sukaro hakɛ jateminɛnan ye .
• Triglycérides ni kolosinsinnan hakɛ kunbɛnni: Fura minnu bɛ kɛ da la, an kofɔra ka tɛmɛ minnu bɛ sukarodunbana furakɛ, olu bɛ se ka kolosinsinnanw hakɛ kunbɛn tuma caman na. aw ka dɔgɔtɔrɔ bɛ se ka statiniw fana di aw ma , i n' a fɔ rosuvastatin ni pravastatin . Triglycéride hakɛ caman bɛ mɔgɔ minnu na, olu ka kan ka asidi fibriki bɔlenw walima asidi tuluma n-3 caman ta , i n’a fɔ minnu bɛ sɔrɔ jɛgɛtulu la.
• Ɲɛgɛnɛsiraw opereli ni u kɛcogo: Fasabɔyɔrɔ bɛ mɔgɔ minnu na, ɲɛgɛnɛsiralabanaw yɔrɔw la, i n’a fɔ ɲɛda, disi ani cɛya yɔrɔw, olu bɛ se ka ɲɛgɛnw kɛ walasa k’u yecogo ɲɛ ani ka u yɛrɛ jigi da u yɛrɛ kan. Plastiki operelikɛlaw bɛ se ka farikolo tulumafɛnw cili kɛ u yɛrɛ ye, ka ɲɛda labɛn kokura ni flaps hɔrɔnmaw ye, ani ka silikoni walima fɛn wɛrɛw don a la. U bɛ se ka tulumafɛnw bɔli walima opereli bɔli fɛɛrɛw fana kɛ walasa ka tulumafɛnw bɔ yɔrɔw la minnu man ɲi i n’a fɔ dawolo walima kɔ kɔfɛ (a ka ca a la a bɛ fɔ a ma ko "buffalo hump" ).

Dɔnniyakɛlaw ka kan ka fɛn caman dɔn hali bi farikolojidɛsɛ furakɛcogo n’a furakɛcogo kan. Ni u bɛ fɛn caman dɔn farikoloɲɛnajɛ kɛcogo gɛlɛnw kan, furakɛli suguya caman bɛ se ka sɔrɔ.

Yala farikolojidɛsɛ bɛ se ka bali wa?

A ka ca a la, Lipodystrophie tɛ se ka bali.

Lipodistrophie (banakisɛfagalan) suguya minnu bɛ sɔrɔ jamu fɛ, olu tɛ se ka bali, barisa u bɛ sɔrɔ jamu jiginni ciyɛntalen dɔ fɛ. Ni aw b’a fɛ ka den sɔrɔ, aw bɛ farati min bɛ den sɔrɔli la, ni o ye bana ye, o faamu ani ka kuma aw ka dɔgɔtɔrɔ fɛ jamu sɛgɛsɛgɛli ko la.

A ka ca a la, farikolojidɛsɛ sɔrɔli bɛ sɔrɔ banakisɛ walima farikolo tangacogo bana fɛ. Hali ni banakisɛ dɔw, i n’a fɔ kɔnɔboli ni sɔgɔsɔgɔninjɛ, bɛ se ka bali ni boloci ye, banakisɛ wɛrɛw ni farikolo tangalanw ka bana minnu bɛ sɔrɔ farikolojidɛsɛ sɔrɔli fɛ, olu tɛ se ka bali.

Lipodystrophie (banakisɛfagalan) ɲɛfɔli ye mun ye?

Lipodystrophie (banakisɛfagalan) jateminɛcogo bɛ bɔ kosɛbɛ lipodystrophie suguya min na, ani ni bana wɛrɛw walima gɛlɛya wɛrɛw bɛ aw la minnu bɛ tali kɛ a la, i n’a fɔ sukarodunbana, sugunɛ walima sugunɛ gɛlɛyaw.

Tulumafɛnw ka dɔgɔn yɔrɔw ni tulumafɛnw bɛ yɔrɔ minnu na, olu latilenni ni ɲɛgɛnw ye, o bɛ dɛmɛ ka farikolojidɛsɛbana bɛ mɔgɔ minnu na, olu ka ɲɛnamaya kɛcogo ɲɛ.

Ni a sɔrɔla ko farikolojidɛsɛ bɛ aw walima aw den na, aw bɛ kuma aw ka dɔgɔtɔrɔ fɛ aw ka kan ka min makɔnɔ ani ka bana in kunbɛn cogo ɲuman na.

Tuma jumɛn na aw ka kan ka taa dɔgɔtɔrɔso la farikolojidɛsɛ ko la?

Ni aw y’a ye ko aw walima aw den farikolo tulu bɛ ka dɔgɔya yɔrɔ kɛrɛnkɛrɛnnenw na, walima ko tulu bɛ ka caya yɔrɔ dɔw la, aw bɛ kuma aw ka dɔgɔtɔrɔ fɛ.

Ni a sɔrɔla ko Lipodystrophie (Lipodystrophie) bɛ aw walima aw den na, aw ka kan ka to ka ɲɔgɔn sɔrɔ ni aw ka dɔgɔtɔrɔso jɛkulu ye walasa ka a dɔn ko aw ka furakɛli bɛ baara kɛ aw ye ka ɲɛ.

A laban na, fɛn minnu ka kan ka to an hakili la

Lipodystrophie ye bana ye min man teli ka sɔrɔ nka a ka jugu. Hali ni fura tɛ yen, furakɛli dɔw bɛ se ka dɛmɛ don ka a taamasiɲɛw ni a ni ɲɔgɔn cɛ banaw kunbɛn, i n’a fɔ sukarodunbana ani kolosinsinnan hakɛ min tɛ a cogo la.

Furakɛli bɛ danfaraba don mɔgɔ ni mɔgɔ cɛ. O la, aw ka dɔgɔtɔrɔso jɛkulu bɛna baara kɛ ni aw ye walasa ka fɛɛrɛ dɔ labɛn min ka fisa aw ma. Aw kana siran ka ɲininkaliw kɛ aw ka dɔgɔtɔrɔ la. U bɛ yen walisa k’i dɛmɛ. O dɔnniya bɛna i dɛmɛ tiɲɛ na ka ɲɛnamaya kɛ kɛnɛya la!

` farikolojidɛsɛ, tulumafɛnw, lɛptini, jamu, sɔrɔlen, sukarodunbana, kolosinsinnan, triglycérides, sidabana, farikoloɲɛnajɛ banaw