Yala i delila k’i ka joli sɛgɛsɛgɛli jaabiw lajɛ, ka daɲɛ surunw kɔlɔsi i n’a fɔ ALT (SGPT), AST (SGOT), walima ALP , ani k’i yɛrɛ ɲininka ko: ‘Nin bɛɛ kɔrɔ ye mun ye?’. Laala aw ka dɔgɔtɔrɔ y’a fɔ ko ‘aw ka ALP bɛ wuli dɔɔni; an ka sɛgɛsɛgɛli kɛ dɔɔnin,’ i ye jɔrɔnanko barikama dɔ sɔrɔ. A bɛ kɛ cogo la pewu ka hami. Bi, an bɛna ALP ye min ye tigitigi, mun na a nafa ka bon i farikolo ma, ani hakɛ kɔrɔtalen kɔrɔ ye min ye tiɲɛ na, an bɛna o tiɲɛ, cogo nɔgɔman ni jɛlen na, i bɛ se ka min faamuya nɔgɔya la.
Ni an bɛ kuma nɔgɔya la, ALP ye mun ye?
Hali n’an fanba b’a Dɔn a surunyalen fɛ, n’o ye ALP ye, a tɔgɔ dafalen ye Alkaline Phosphatase ye. Nin ye farikolojɔli dumuni suguya kɛrɛnkɛrɛnnen ye min bɛ sɔrɔ i farikolo la a yɛrɛ la—kɛrɛnkɛrɛnnenya la, anzimu .
I bɛ se k’i yɛrɛ ɲininka ko: ‘Anzimu ye mun ye tigitigi?’ Miiri i farikolo la iko izini belebeleba, min bɛ baara kɛ kosɛbɛ. Walasa ka baara teliya ani ka baara kɛ ka ɲɛ, o izini in bɛ a jigi da baarakɛla kɛrɛnkɛrɛnnenw kan. Enzymes (enzymes) ye o de ye tigitigi. U ye selilɛri baarakɛla misɛnninw ye minnu bɛ kemikaliya wale nafamaw teliya i farikolo kɔnɔ.
ALP anzimu jɔyɔrɔ ka bon farikolo baara nafama caman na, i n’a fɔ:
- Aw bɛ dɛmɛ don ka farikolojɔli dumuniw tiɲɛ aw bɛ dumuni minnu dun walasa aw farikolo ka se k’u minɛ.
- Dɛmɛ don dumunikɛcogo bɛɛ la.
- Dɛmɛni balofɛn nafamaw tali la.
ALP bɛ sɔrɔ a hakɛ caman na aw ka sugunɛ na , o de kama a ka ca a la a bɛ fɔ a ma ko sugunɛbilenni. Nka, sugunɛ kɔfɛ, ALP bɛ sɔrɔ fana aw kolo, banakɔtaa , ani sugunɛ na , ka fara musokɔnɔmaw ka denso kan.
ALP ye I Farikolo Kɔnɔna Taamaʃyɛn ye
I ka ALP hakɛ bɛ kɛ i n’a fɔ fɛn min bɛ kɛ i farikolo kɔnɔ, o jiralan min bɛ se ka suman—i n’a fɔ lasɔmini yeelen min bɛ i ka mobili dashboard kan. Ni o lanpan mana mana, i b’a dɔn ko mobili mago bɛ jateminɛ na. O cogo kelen na, ni aw ka ALP hakɛ ka ca walima ka dɔgɔn ka tɛmɛ a cogo kɔrɔ kan, o bɛ kɛ biyomarkɛri (taamaʃyɛn) nafama ye min b’a jira ko ko dɔ bɛ se ka kɛ a kɔnɔ, i n’a fɔ farikolo yɔrɔw tiɲɛni walima sugunɛbana.
Jɛɲɔgɔnya min bɛ ALP sɛgɛsɛgɛli ni PBC (Kɔlangitis biliaire fɔlɔ) cɛ .
Ni taamasiɲɛw bɛ aw la minnu bɛ tali kɛ aw ka sugunɛ na, aw ka dɔgɔtɔrɔ bɛ se ka ALP sɛgɛsɛgɛli fɔ aw ye. nin sɛgɛsɛgɛli in nafa ka bon kosɛbɛ bana dɔ sɛgɛsɛgɛli la min bɛ wele ko sɔgɔsɔgɔninjɛ fɔlɔ ( PBC ) .
N’an y’a fɔ cogo nɔgɔman na, PBC ye sugunɛbana basigilen ye min kɔnɔ, i ka sugunɛbilenni sira misɛnninw bɛ tiɲɛ. O bɛ bile bali ka woyo ka ɲɛ, o bɛ kɛ sababu ye ka a caya ani ka se ka aw ka sugunɛbara tiɲɛ.
A ka c’a la, dɔgɔtɔrɔ bɛ baara kɛ ni ALP sɛgɛsɛgɛli ye walasa ka:
1. Aw bɛ a sɛgɛsɛgɛ ni PBC bɛ aw la.
2. Aw bɛ bana in taabolo kɔlɔsi ni a sɔrɔla ko PBC bɛ aw la kaban (ka a lajɛ ni a bɛ sabati, ni a bɛ ka ɲɛ, walima ni a bɛ ka juguya).
3. Aw bɛ aw ka furakɛli min bɛ senna , aw bɛ o nafa jateminɛ .
Nin ALP joli sɛgɛsɛgɛli in ye fɛɛrɛ ye min bɛ se ka kɛ kosɛbɛ, min tɛ fɛn caman kɛ walasa ka kɛnɛyaso kuntaalajan kuntaalajan fɔ. Sɛgɛsɛgɛliw y’a jira ko ALP hakɛ bɛ se ka dɛmɛ don ka bana in taabolo nataw fɔ, hali a daminɛ na.
Kɔrɔbɔli suguya minnu bɛ kɛ ka ALP suman
Sɛgɛsɛgɛli suguya fɔlɔ fila bɛ yen minnu bɛ kɛ ka ALP hakɛ jateminɛ i joli la, olu bɛ kɛ ka kɛɲɛ ni dɔgɔtɔrɔ ka laadilikanw ye.
| Kɔrɔbɔli suguya | Cogojirali |
|---|---|
| ALP sɛgɛsɛgɛli kɛcogo kɔrɔ (ALP sɛgɛsɛgɛli caman) . | Nin ye sɛgɛsɛgɛli ye min ka teli ka kɛ, a ka ca a la, a bɛ yamaruya ka kɛ sugunɛbilennikɛlan dɔ ye walima farikolojidɛsɛbanakisɛfagalan bɛɛ lajɛlen (CMP). A bɛ ALP hakɛ bɛɛ suman aw joli la. |
| ALP Izoenzyme sɛgɛsɛgɛli | Nin ye sɛgɛsɛgɛli ye min ɲɛfɔlen don kosɛbɛ ani min kɛrɛnkɛrɛnnen don. A bɛ se k’a jira tigitigi ALP min bɛ aw joli la, o bɛ bɔ yɔrɔ min na—misali la, a bɛ bɔ aw ka sugunɛ na walima aw kolo la. Ni aw ka ALP jaabiw hakɛ dantigɛlen tɛ, aw ka dɔgɔtɔrɔ bɛ se ka o yamaruya walasa ka a bɔyɔrɔ tigitigi dɔn. |
Yala aw ka kan ka hami ni aw ka ALP hakɛ cayara wa?
O ye haminanko ye min ka teli ka kɛ. Fɔlɔ ni fɔlɔ, aw kana siran ni aw ka ALP hakɛ wulila dɔɔni. ALP hakɛ cayalenba tɛ a jira tuma bɛɛ ko sugunɛbana jugumanba bɛ i la.
Kun caman bɛ sugunɛbana kɔfɛ minnu bɛ se ka kɛ sababu ye ka aw ka ALP hakɛ wuli:
- Denmisɛnw ni funankɛninw minnu bɛ ka bonya: Ikomi u kolo bɛ ka bonya joona, u ka ALP hakɛ bɛ caya u yɛrɛ la ka tɛmɛ balikuw ta kan.
- Kɔnɔmaya : Ikomi denso bɛ ALP bɔ, a tɛ kɛ pewu ni a hakɛ bɛ wuli kɔnɔmaya waati.
- Fɛn minnu bɛ tali kɛ kolo la: Aw ka ALP hakɛ bɛ se ka caya ni kolo karilen bɛ kɛnɛya walima ni kolotuguda bana wɛrɛw bɛ a la.
- Fura dɔw: Fura dɔw minnu bɛ sɛbɛn dɔgɔtɔrɔso la walima minnu tɛ sɔrɔ dɔgɔtɔrɔso la, olu bɛ se ka aw ka ALP hakɛ caya waati dɔɔni.
Ni haminanko dɔw bɛ aw la ALP hakɛw kan aw ka laboratuwari rapɔɔri kan, aw bɛ aw yɛrɛ tanga aw yɛrɛ sɛgɛsɛgɛli ma ɛntɛrinɛti ɲininiw fɛ. Fɛɛrɛ min ka fisa ani min farati ka bon, o ye ka baro kɛ o nɔfɛkow kan ni aw ka kɛnɛyabaarakɛla ye.
Aw ka dɔgɔtɔrɔ tɛna sɛgɛsɛgɛli kɛ abada ka da aw ka ALP hakɛ dɔrɔn kan. U bɛna aw ka kɛnɛya bɛɛ jateminɛ ni aw ye aw ka bana taamasiɲɛw lajɛ, joli sɛgɛsɛgɛli taamasiɲɛ wɛrɛw (i n’a fɔ ALT/SGPT ani bilirubine), aw si hakɛ, ani aw bɛ fura minnu ta . Ka to i hakili sigilen na ani ka tugu dɔgɔtɔrɔw ka laadilikanw kɔ, o ye i ka fɛɛrɛ nata ɲuman ye tuma bɛɛ.
Takeaways (Takeaways) kunbabaw
- ALP (Alkaline Phosphatase) ye farikolojɔlifɛn nafama ye, a bɛ sɔrɔ fɔlɔ sugunɛ ni kolotugudaw la.
- Ni ALP hakɛ cayara aw ka joli la, o bɛ se ka kɛ biyomarkɛri (taamaʃyɛn) ye min b’a jira ko sugunɛ walima kolo gɛlɛyaw bɛ se ka sɔrɔ.
- Nka, ALP hakɛ min bɛ wuli a yɛrɛ la, o tɛ kojugu ye pewu denmisɛnw ni musokɔnɔmaw la minnu bɛ ka bonya.
- Aw kana a ɲini abada ka aw yɛrɛ sɛgɛsɛgɛ ka da laboratuwari nafa kelen kan; o kɛli bɛ se ka jɔrɔnanko kunntanw lase mɔgɔ ma.
- Ni ɲininkali dɔw bɛ aw fɛ aw ka laboratuwari jaabiw kan, fɛɛrɛ min ka fisa ni fɛɛrɛ tɔw bɛɛ ye ani min bɛ se ka da a kan, o ye ka dɔgɔtɔrɔ ɲininka walasa ka ɲɛfɔli jɛlen sɔrɔ.
ALP, Alkaline Phosphatase, joli sɛgɛsɛgɛli, sugunɛ, sugunɛbaralabana, joli laseli, PBC, Primary Biliary Cholangitis, farikolo kɛnɛya
