Ne mía dometɔ akpa gãtɔ se nya suklidɔ la, míebunɛ be enye dɔléle si gblẽa nu le ŋutilã me sukli ƒe agbɔsɔsɔ, dzi, ayiku, kple ŋkuwo ŋu. Nyateƒee. Gake ɖe nènyaa, numekuku siwo wowɔ nyitsɔ laa ɖee fia be suklidɔ ate ŋu akpɔ ŋusẽ ɖe míaƒe ahɔhɔ̃ kple ŋkuɖoɖonudzi hã dzi tẽ. Ðɔkta aɖewo gɔ̃ hã le ŋkɔ yeye zãm na nɔnɔme sia, si nye ‘Suklidɔ Ƒomevi 3’. Eyata egbea, mina míaƒo nu tso nya sia ŋu.
Nuka tututue nye suklidɔ si nye ‘Type 3’?
Kpuie ko la, ‘Suklidɔ Ƒomevi 3 lia’ nye ŋkɔ si eŋutinunyala aɖewo do ɖa na Alzheimer ƒe dɔlélea. Nusitae nye be woxɔe se be nu vevitɔ si gbɔ Alzheimer-dɔléle ƒomevi aɖewo tsonae nye nusiwo suklidɔ ate ŋu agblẽ le ahɔhɔ̃a ŋu le ɣeyiɣi aɖe megbe.
Ɣeyiɣi didi aɖe la, dzɔdzɔmeŋutinunyalawo susui be lãmetsi si nye insulin meku ɖe ahɔhɔ̃a ƒe dɔwɔwɔ ŋu kura o. Gake fifia míenya be menye nenemae o. Insulin hã zɔa mɔ yia míaƒe ahɔhɔ̃menugbagbeviwo me. Eye insulin sia le vevie ŋutɔ na míaƒe tamebubu kple ŋkuɖoɖonudzi.
Eyata ne wò ahɔhɔ̃ mexɔ insulin si sɔ o, alo ne mete ŋu zã insulin si wòxɔna nyuie o (míeyɔa esia be insulin ƒe dɔlélenutsiŋutete) la, ahɔhɔ̃menugbagbeviwo ƒe gbesiagbe dɔwɔwɔ dzea gbegblẽ gɔme. Esiae dzɔna le Alzheimer-dɔlélea me.
Gake nu ɖeka aɖe le vevie be míaɖo ŋku edzi. ‘Suklidɔ ƒomevi 3 lia’ menye atikewɔwɔ me dɔléle si dzi woda asi ɖo haɖe o. Egakpɔtɔ le numekuku ƒe afɔɖeɖea me. Eyata ɖɔkta aɖeke magblɔ na wò le se nu be ‘suklidɔ Ƒomevi 3 lia’ le ŋuwò o.
Nukatae esia le dzɔdzɔm? Nukawoe nye susu siwo tae?
Numekukuwo ɖee fia kɔte be amesiwo ŋu suklidɔ do ŋgɔ alo suklidɔ ƒomevi evelia le la le afɔku me be woaxɔ Alzheimer kple tagbɔdɔ bubuwo le woƒe tsitsime. Nu geɖe gbɔe esia tso.
1. Ʋukawo ƒe gbegblẽ kple woƒe dɔdzẽ
Suklidɔ nana dzidɔ kple ʋusɔgbɔdɔ ƒe afɔkua dzina ɖe edzi. Azɔ hã, ne sukli ƒe agbɔsɔsɔ le ʋu me dzi ɖe edzi la, dɔdzẽ dzɔna le ŋutilãa me. Esia menyo na míaƒe ʋukawo o. Ne ʋuka tsɛ siwo le ahɔhɔ̃a me gblẽ alea la, ate ŋu aʋu mɔ na Alzheimer-dɔlélea.
2. Kadodo si le lãmekawo ƒe lãmenugbagbeviwo dome ƒe tɔtɔ
Ne sukli ƒe agbɔsɔsɔ le ʋu me dzi ɖe edzi la, protein ƒe ƒuƒoƒo siwo woyɔna be beta-amyloid ƒoa ƒu ɖe ahɔhɔ̃a me. Ƒuƒoƒo siawo ƒoa ƒu eye wotsia ahɔhɔ̃meka siwo le ahɔhɔ̃a me dome. Abe ʋuwo ƒe xaxa le mɔ dzi ene la, protein ƒe ƒuƒoƒo siawo xea mɔ na lãmekawo be woagaɖo dze kple wo nɔewo o. Esia nye Alzheimer-dɔlélea ƒe akpa vevi aɖe.
3. Tau protein ƒe ʋuʋu
Tsɔe be mɔ̃ suesuesuewo (microtubules) ƒe ɖoɖo aɖe le míaƒe ahɔhɔ̃a me si tsɔa nunyiamewo yia ŋgɔ kple megbe le lãmekawo me. Protein aɖe si woyɔna be tau wɔa dɔ abe ‘dzɔla’ ene be wòana mɔ̃memi ƒe ɖoɖo sia nanɔ ɖoɖo nu eye wòagatra o. Le amesi ŋu Alzheimer-dɔléle le ƒe ahɔhɔ̃ me la, tau protein sia xaxana. Emegbe mɔ̃awo ƒe ɖoɖoa xea mɔ, lãmenugbagbeviawo mete ŋu tsɔa nusi wohiã o, eye lãmenugbagbeviawo kuna. Numekuku aɖewo ɖee fia be tau protein siawo siwo xaxa la sɔ gbɔ wu le suklidɔlélawo ƒe ahɔhɔ̃ me.
4. Insulin ƒe Tsitretsitsi
Esiae nye ‘suklidɔ Ƒomevi 3’ ƒe susua ƒe dzi. Abe lãmenugbagbevi siwo le ŋutilãa me ene la, ne ahɔhɔ̃mekawo mewɔa nu ɖe insulin ŋu nyuie o la, ŋusẽ (mɔ̃memi) si lãmenugbagbevi mawo mekpɔna o. Emegbe ahɔhɔ̃a ƒe dɔwɔwɔ gblẽna. Azɔ hã, insulin ƒe dɔlélenutsiŋutete le ahɔhɔ̃a me dzia nɔnɔme gbegblẽ aɖe si woyɔna be oxidative stress ɖe edzi.
| Nu bubu siwo nana afɔkua dzina ɖe edzi | |
|---|---|
| Domenyiŋusẽfianu ƒe Nuwo | Domenyiŋusẽfianu aɖe si woyɔna be APOE4 le Alzheimer dɔnɔ siwo wu afã si. Wokpɔe be domenyiŋusẽfianu sia nana wòsesẽna na ahɔhɔ̃a be wòazã insulin. |
| Agbenɔnɔ ƒe nɔnɔme | - Nuteɖeamedzi si nɔa anyi didi - Kamedede ƒe anyimanɔmanɔ - Nuɖuɖu si me calorie, sukli kple ami sɔ gbɔ ɖo, eye fibre mesɔ gbɔ o |
Nukawoe ate ŋu anye nɔnɔme sia ƒe dzesiwo?
Dzesi siwo do ƒome kple ‘Suklidɔ Ƒomevi 3’ ƒe nukpɔsusua sɔ kple Alzheimer ƒe dɔlélea tɔ. Woate ŋu akpɔ nusiawo le gɔmedzedzea me.
| Dzesiwo ƒe hatsotso | Kpɔɖeŋuwo |
|---|---|
| Kuxi siwo le ŋkuɖoɖonudzi kple tamebubu me | - Ŋkeke veviwo alo nudzɔdzɔwo ŋɔŋlɔ be. - Nya ɖeka ma ke biabia zi gbɔ zi geɖe. - Nane si me afɔɖeɖe geɖe le la yometiti sesẽ, abe nuɖaɖa ene. - Nya si nèdi be yeagblɔ esime nèle nu ƒom la ŋɔŋlɔ be. |
| Tɔtrɔ siwo va le gbesiagbedɔwo me | - Ŋlɔ alesi woazã mɔ̃ si wozã ɣeyiɣi didi aɖee nye sia (e.g. TV remote) be. - Nusiwo wogblẽ ɖe teƒe siwo womenya o. - Ðetsɔleme si bu ɖe dzadzɛnyenye ŋu. - Nyametsotso gbegblẽwo wɔwɔ ku ɖe ga ŋu. |
| Nuwɔna kple seselelãme trɔna | - Vivivi la, ɖokuiwò ɖeɖe ɖa tso xɔlɔ̃wo kple ƒometɔwo gbɔ. - Ame ƒe didi be yeado le yeƒe ‘akɔfafa ƒe teƒe’ o. - Dzikudodo alo dzimaɖitsitsi bɔbɔe. |
Ne dzesi siawo dometɔ aɖe le ŋuwò alo wò lɔlɔ̃tɔ aɖe ŋu, vevietɔ ne suklidɔ le ŋuwò hã la, taflatse ƒo nu tso wo ŋu na wò ɖɔkta. Mègaŋe aɖaba ƒu wo dzi o.
Mina míasrɔ̃ nu tso dɔlélewo didi kple edada ŋu.
Abe alesi míegblɔe va yi ene la, womegblɔ be suklidɔ ƒomevi 3 le ame si le se nu o, eyata ɖɔkta mate ŋu awɔ dodokpɔ aɖe atsɔ aɖo kpe edzi o. Gake ne wò ŋkuɖoɖonudzi ƒe kuxiwo le fu ɖem na wò la, wò ɖɔkta ado wò kpɔ be tagbɔdɔ le ŋuwò hã.
Esia ate ŋu anye susu ƒe nɔnɔme ŋuti nyabiasewo, ahɔhɔ̃mekadodo (MRI alo CT scan), kple ɣeaɖewoɣi aklã me tsi dodokpɔ.
Ne míeƒo nu tso atikewɔwɔ ŋu la, atikewɔwɔ aɖeke koŋ meli na ‘Suklidɔ Ƒomevi 3’ o. Gake nu vevi eve aɖewo li nàte ŋu awɔ:
1. Ne suklidɔ le ŋuwò la, ke ɖu edzi nyuie. Ele vevie be nàzã atike si wò ɖɔkta ŋlɔ na wò pɛpɛpɛ eye nàkpɔ sukli ƒe agbɔsɔsɔ le ʋu me dzi.
2. Di Alzheimer-dɔlélea ƒe atike siwo li fifia. Togbɔ be atikewɔmɔnu siawo mate ŋu ada dɔlélea keŋkeŋ o hã la, woate ŋu akpe ɖe ame ŋu wòaɖe alesi dzesiawo nu sẽna ɖe edzii dzi akpɔtɔ.
Numekuku aɖewo ɖee fia hã be suklidɔtike aɖewo, abe metformin kple pioglitazone ene, ate ŋu aɖe tagbɔdɔléle xɔxɔ ƒe afɔkua dzi akpɔtɔ le eƒe tsitsime. Wogale numekuku bubuwo wɔm.
Aleke nàwɔ akpɔ wò ahɔhɔ̃ ƒe lãmesẽ ta ahaɖe afɔku sia dzi akpɔtɔ?
Be míanɔ dedie tso afɔku sia me la, nu vevi aɖewo li míate ŋu atsɔ akpe ɖe míaƒe agbenɔnɔ ŋu. Esiawo nyo ŋutɔ na wò ahɔhɔ̃ ƒe lãmesẽ, kpakple wò ŋutilã bliboa hã.
- Nɔ dɔ dzi: De kame aɖabaƒoƒo 30 gbesiagbe, ŋkeke 5 ya teti le kwasiɖa me. Tia nane si doa dzidzɔ na wò. Ate ŋu anye azɔlizɔzɔ, ɣeɖuɖu, alo gasɔdodo.
- Ƒo asa na atamanono: Ne ènoa atama la, bia wò ɖɔkta be wòakpe ɖe ŋuwò nàdzudzɔ.
- Na wò kpekpeme nanɔ lãmesẽ me: Ƒo atikutsetsewo, amagbewo, nuku blibowo (abe bli dzẽ ene), lã siwo me ami mele o, kple nyinotsi siwo me ami mesɔ gbɔ ɖo o geɖe wu. Ðe sukli kple ami siwo me ami sɔ gbɔ ɖo dzi kpɔtɔ.
- Lé be na wò ʋu ƒe sisi: Ne wò ɖɔkta ŋlɔ atike na wò la, ke noe abe ale si tututu wògblɔe ene.
- Mlɔ anyi nyuie: Dze agbagba nàdɔ alɔ̃ nyuie gaƒoƒo 7-8 gbesiagbe.
- Dze ha kple amewo: Zã ɣeyiɣi ɖe xɔ̃wòwo kple ƒometɔwo ŋu. Akogotsitsi kple ame ɖokui ɖeɖe ɖe aga menyo na ahɔhɔ̃a o.
- Srɔ̃ nu yeyewo: Nuwo abe gbe yeye sɔsrɔ̃, haƒonu aɖe sɔsrɔ̃, alo nyabiasewo gbɔ kpɔkpɔ ene tua kadodo yeyewo ɖo le ahɔhɔ̃menugbagbeviwo dome.
Gbedasi si Wotsɔ Yi Aƒeme
- ‘Suklidɔ ƒomevi 3 lia’ nye nya si wozãna tsɔ ɖɔa ahɔhɔ̃ ƒe gbegblẽ si suklidɔ hena vɛ si ate ŋu ahe Alzheimer dɔléle vɛ. Gake esia menye dɔléle si dzi dziɖuɖua da asi ɖo haɖe o.
- Sukli ƒe agbɔsɔsɔ si sɔ gbɔ ɖe ʋu me kple insulin ƒe dɔmawɔmawɔ nyuie ate ŋu agblẽ nu le wò ahɔhɔ̃menugbagbeviwo ŋu vevie eye wòagblẽ nu le ŋkuɖoɖonudzi ŋu.
- Ne suklidɔ le ŋuwò la, wò ʋumesukli ƒe agbɔsɔsɔ dzi kpɔkpɔ nyuie le vevie ŋutɔ na wò ŋutilã kple ahɔhɔ̃ ƒe lãmesẽ.
- Ne ède dzesii be yeƒe ŋkuɖoɖonudzi bu alo tɔtrɔ aɖe, vevietɔ ne suklidɔ le ŋuwò la, mègaŋe aɖaba ƒu edzi o eye nàƒo nu kple wò ɖɔkta enumake.
- Ne èwɔ ɖe agbe nyui nɔnɔ dzi (nuɖuɖu nyui, kamedede, hadede) la, àte ŋu akpɔ wò ŋutilã kple wò ahɔhɔ̃ siaa ta.
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