Mía dometɔ geɖe vɔ̃na ne míese nya ‘No me Dɔdzẽ ’, alo? Gake ènya be menye dɔléle ƒomevi ɖeka koe esia nye o, ɖe ƒomevi vovovowoe li? Kansa ƒomevi si tututu le ŋuwò nyanya le vevie ŋutɔ le atikewɔwɔ si nàxɔ me. Eyata mina míaƒo nu tso esia ŋu bɔbɔe ŋutɔ eye le xɔlɔ̃wɔwɔ me egbea. Nu siawo nyanya anye ŋusẽ gã aɖe na wò.
Kansa ƒe hatsotsowo me toto le afisi wòdze egɔme tsoe nu
Mɔ ɖeka si dzi ɖɔktawo ɖɔa no me dɔdzẽ le enye afisi wòdze egɔme tsoe le ŋutilãa me kple ne ekaka.
Kpuie ko la, no me dɔdzẽ akpa gãtɔ nye esiwo woyɔna be carcinoma. Esia fia be wodzea egɔme tso lãkusi siwo le no ƒe eme kple ŋutinu bubuwo me. Esiawo ƒe akpa gãtɔ dzena le ƒomevi sue si woyɔna be adenocarcinoma me. Esiawo nye kansa siwo dzea egɔme tso no ƒe mɔ̃ siwo tsɔa notsi alo notsi ƒe lãkusiwo (lobules) me.
Ductal Carcinoma ƒe dɔléle
Esiae nye no me dɔdzẽ ƒomevi si bɔ wu. Akpa vevi eve hã le eŋu.
1. Ductal Carcinoma In Situ (DCIS): Esiae nye no me dɔdzẽ ƒe gɔmedzedze . Nya 'In Situ' gɔmee nye "afisi wòle." Esia fia be notsi ƒe mɔ̃awo me koe kansa lãmenugbagbeviwo gakpɔtɔ le. Womekaka ɖe gota o. Esia ƒomevie nye no me dɔdzẽ siwo ŋu wokpɔ yeyee abe 1 le 5 ɖesiaɖe me ene. Akpa nyuitɔ kekeakee nye be woate ŋu ada atike sia ƒomevi keŋkeŋ kloe.
2. Invasive Ductal Carcinoma (IDC): Esiae nye no me dɔdzẽ ƒomevi si bɔ wu . Exɔa no me dɔdzẽ siwo katã wokpɔ la ƒe 80% lɔƒo. 'Amedzidzedze' gɔmee nye "amedzidzedze." Esia fia be kansadɔlékuiawo kaka ɖe notsitowo godo kple lãmenugbagbevi siwo ƒo xlã wo me. IDC sia ƒomevi ƒe hatsotso sue geɖewo li. Togbɔ be wosesẽ vie hã la, mina míalé ŋku ɖe wo ŋu bɔbɔe.
| IDC ƒe Ƒomevi Sue | Numeɖeɖe bɔbɔe aɖe |
|---|---|
| Medullary Carcinoma ƒe dɔléle si woyɔna be Medullary Carcinoma | Exɔ ŋkɔa elabena edze abe ahɔhɔ̃meka falɛfalɛwo ene. Ƒã ŋutɔ (mede 5%) o. |
| Mucinous Carcinoma ƒe dɔléle | Nu geɖe si le abe ʋuʋudedi ene (mucin) ƒo xlã kansa lãmenugbagbeviwo. Esia hã mebɔ o (mede 2%) o. |
| Dɔdzẽ si le ʋukawo me | Nusiwo le abe mɔ̃ ene le kansa lãmenugbagbeviwo me le wo me. Zi geɖe la, amesiawo tsina ɖe hatsotsowo me eye wowɔa nu nyuie ne wowɔ atike na wo. |
| Papillary Carcinoma ƒe dɔléle si woyɔna be Papillary Carcinoma | Kansa lãmenugbagbeviwo ƒe do (papules) siwo le abe asibidɛ ene li. Wobɔ ɖe nyɔnu tsitsiwo me. |
| Cribriform Dɔdzẽ ƒe Dɔdzẽ | Woate ŋu akpɔ nɔnɔme aɖe si le abe togbɛ ene le kansa sia si mebɔ o ƒe lãmenugbagbeviwo dome. |
Lobular Carcinoma ƒe dɔléle si woyɔna be Lobular Carcinoma
Le ƒomevi sia me la, lãmenugbagbevi siwo mesɔ o tsina le no ƒe lãkusi siwo naa notsi (lobules) ƒe lãkusi me.
- Invasive Lobular Carcinoma (ILC): Esiae nye no me dɔdzẽ ƒomevi evelia si bɔ wu. Kansa sia ƒomevi dzea egɔme tso no me eye wòkakana ɖe lãkusi siwo ƒo xlãe me. Emegbe ate ŋu akaka ɖe ŋutilã ƒe akpa bubuwo abe ʋuka siwo me ʋu sina tona ene.
- Lobular Carcinoma in Situ (LCIS): Mègavɔ̃ na ŋkɔ sia o. Ðɔktawo mebua LCIS ŋutɔŋutɔ be enye kansa o elabena mekakana ɖe no godo o. Gake LCIS ƒe amesinɔnɔ fia be afɔku si le eme be nàxɔ no me dɔdzẽ le etsɔme la lolo vie .
No me dɔdzẽ ƒomevi bubu siwo mebɔ o
Esiawo mebɔ boo o, gake enyo be míanya nu tso wo ŋu.
- No me dɔdzẽ si me dɔdzẽ le: Esia nye esi mebɔ kura o (si mede 5%) o eye wòsẽ ŋutɔ. Eƒe dzesiwo to vovo na bubuawo. Kansa lãmenugbagbeviwo xea mɔ na ʋuka siwo me ʋu sina tona le no me. Esia nana noa vuvu, biãna, eye ŋutigbalẽa ƒoa ƒu . Ɣeaɖewoɣi la, no ƒe ŋutigbalẽ ate ŋu adze abe amititsetse ƒe aŋgba ene . Esia ƒomevi ate ŋu akaka kabakaba.
- Phyllodes Tumor: Esiawo nye dɔdzẽ siwo mebɔ o siwo dzɔna le no ƒe kadodoŋusẽ me. Wo dometɔ 1 le 4 ɖesiaɖe me koe va zua kansa. Susu mamlɛawo nye dɔdzẽ siwo me dɔlékui aɖeke mele o.
- Angiosarcoma: Kansa sia dzɔna le ʋukawo kple ʋuka siwo me ʋu sina tona me. Ame siwo xɔ wu ƒe 70 mee wòbɔ ɖo wu.
- Paget ƒe Dɔléle : Esia hã mebɔ kura o. Enye kansa si dona le no me kple nuto si ƒo xlãe (areola). No ƒe ŋutigbalẽ ate ŋu azu ʋuʋudedi, abiã, eye wòaƒo . Kansa ƒomevi aɖe si woyɔna be DCIS alo IDC hã le ame geɖe siwo ŋu Paget ƒe dɔlélea le la ŋu.
- No me Kansa si kaka ɖe teƒe bubuwo: ‘Metastatic’ fia be kansa la kaka ɖe no godo yi ŋutilã ƒe akpa bubuwo. Ðɔktawo yɔa esia hã be "deŋgɔ" alo "afɔɖeɖe 4 lia." Zi geɖe la, ekakana ɖe aklã, ahɔhɔ̃, ƒuwo, alo lãkusiwo me.
Nu vevitɔe nye be, eɖanye kansa ka ƒomevie o, mɔnukpɔkpɔ si li be woahaya la lolona wu ne wokpɔe kaba eye wodae nyuie.
Kansa ƒe hatsotsowo me toto le domenyiŋusẽfianu kple lãmetsiŋusẽ nu
Ne wokpɔ no me dɔdzẽ le ŋuwò vɔ la, wò ɖɔkta awɔ dodokpɔ tɔxɛ aɖewo le kansadɔlékuiawo ŋu akpɔe ɖa be lãmetsi siwo nye estrogen alo progesterone , alo ne domenyiŋusẽfianu aɖewo koŋ le ŋusẽ kpɔm ɖe kansa la ƒe tsitsi dzi hã.
Dodokpɔ siawo mee ɖɔkta tiaa atike si sɔ wu, si ŋu woɖo taɖodzinu ɖo na wò.
- HER2-positive: Protein si woyɔna be `HER2` (Human Epidermal Growth Factor Receptor 2) le no me dɔdzẽ siwo ade 1 le 5 ɖesiaɖe me. Protein sia kpena ɖe kansa lãmenugbagbeviwo ŋu wotsina. Kansa siwo me HER2 le ate ŋu asẽ ŋu wu. Gake atikewɔmɔnu aɖewo li siwo woɖo taɖodzinu na siwo tɔa ŋku protein sia, si wɔnɛ be wo dada nɔa bɔbɔe.
- Lãmetsiŋusẽ Xɔla-positive alo negative: Teƒe tɔxɛ aɖewo (receptors) le kansa lãmenugbagbevi aɖewo ƒe anyime si dzi lãmetsiŋusẽwo ate ŋu abla ɖe wo ŋu. Bu lãmenugbagbevi la abe ʋɔtru ene, eye xɔla siawo le abe safui siwo le eme ene.
- ER-positive: Dɔlékuixɔla siwo ate ŋu abla ɖe lãmetsi si nye estrogen ŋu le kansa lãmenugbagbeviwo si.
- PR-positive: Dɔlékuixɔla siwo ate ŋu abla ɖe lãmetsi si nye progesterone ŋu le kansa lãmenugbagbeviwo si.
- Hormone receptor-positive fia be eve siawo dometɔ ɖeka alo evea siaa le afima. Esi lãmetsiŋusẽwo kpena ɖe kansa ƒomevi siawo ŋu wotsina ta la, woate ŋu atsɔ atike siwo xea mɔ na lãmetsiŋusẽ (lãmetsiŋusẽtikewo) ada wo dzidzedzetɔe.
- Lãmetsiŋusẽ ƒe xɔla-negative fia be lãmenugbagbevi siawo evea siaa mele wo me o.
- Triple-negative: Esia ƒomevi nyea dɔléle siwo ade 15%. Abe alesi ŋkɔa ɖee fia ene la, estrogen receptor (ETR) le kansa lãmenugbagbevi siawo si., progesterone receptors (PR) kple HER2 katã bu. Eyata womate ŋu atsɔ lãmetsiŋusẽtike alo HER2-dɔdamɔnu si woɖo taɖodzinu na adae o. Esia ate ŋu ana atikewɔwɔ nasesẽ vie, gake atikewɔwɔ bubuwo li, abe atikewɔmɔnu ene.
Ne ènya nya kansa ƒomevi si le ŋuwò ko la, ƒo nu kple wò ɖɔkta gaglãa tso alesi wòkpɔa ŋusẽ ɖe wò hayahaya ƒe mɔnukpɔkpɔ dzi kple atikewɔmɔnu nyuitɔwo ŋu. Mègavɔ̃ be yeabia nyaawo katã o.
Gbedasi si Wotsɔ Yi Aƒeme
- No me dɔdzẽ menye dɔléle ɖeka ko o, ƒomevi vovovo geɖewo li.
- Kansa ƒomevi si le ŋuwò nɔ te ɖe afisi wòdze egɔme tsoe le no me (notsi ƒe mɔ̃wo/lãmenugbagbeviwo), ne ekaka, kple ne lãmetsi aɖewo (ER, PR) alo protein (HER2) gblẽ nu le eŋu dzi.
- Atike ƒomevi aɖewo, abe DCIS ene, ƒe dɔyɔyɔ sɔ gbɔ ŋutɔ, gake ƒomevi aɖewo abe Inflammatory Breast Cancer ene ate ŋu anye esiwo me wowɔa adã le wu.
- Wò kansa ƒe lãmetsiŋusẽ kple domenyiŋusẽfianu (xɔla) ƒe nɔnɔme nyanya le vevie ŋutɔ be wòana atike si wɔa dɔ wu eye wòɖo taɖodzinu na wò wu.
- Mègahe ɖe megbe gbeɖe le nyabiase ɖesiaɖe si le asiwò ku ɖe wò dɔléle si wokpɔ, kansa ƒomevi, kple atikewɔwɔ ƒe ɖoɖo ŋu me dzodzro kple wò ɖɔkta me gbeɖe o. Nyatakaka nana ame nye aʋa si dzi woɖu la ƒe afã.
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