Mina míasrɔ̃ nu tso "bile retention" alo cholestasis ŋu.

Èse “aɖuɖɔtoe ƒe xexe” alo “aɖuɖɔtoemekpe” ŋu nya kpɔa? Ðewohĩ èkpɔ ame aɖewo siwo ƒe ŋkuwo kple ŋutigbalẽ trɔ zu ɣie kpɔ. Èbu nusi tututu nusiawo nye kple nusita wodzɔna ŋu kpɔa? Egbea míele nu ƒom tso nɔnɔme sia tɔgbe ŋu. Woyɔa esia le atikewɔwɔ me be cholestasis. Mègatsi dzi o, mina míaɖe eme bɔbɔe.

Nukae nye Cholestasis?

Kpuie ko la, cholestasis nye ne ʋumenugbagbeviɣi ƒe sisi tso wò aklã me dzi ɖe kpɔtɔ alo tɔ te keŋkeŋ. Bu eŋu abe dɔwɔƒe sue aɖe si le míaƒe ŋutilã me ene. Ewɔa nusi woyɔna be ʋumenugbagbeviɣidɔ . Ʋumenugbagbeviɣi sia kpena ɖe mía ŋu míeɖua nuɖuɖu siwo míeɖuna, vevietɔ nuɖuɖu siwo me ami le.

Aklãa wɔa ʋumenugbagbeviɣi sia eye wòɖonɛ ɖe míaƒe nuɖuɖumeŋusẽ to mɔ̃ suesuesue siwo woyɔna be ʋumenugbagbeviɣimɔ̃wo dzi . Aɖuɖɔtoe siawo dometɔ aɖewo le aklãa me (aklã me ʋukawo) eye ɖewo hã le aklãa godo (aklã me ʋukawo). Dɔlékuiwo ƒe ɖoɖo siae ƒoa aklã, aɖuɖɔtoe, dɔgbo , kple dɔgbo sue la nu ƒu. Esiawo katã ƒo ƒu wɔa ʋumenugbagbeviɣidɔa .

Azɔ bu eŋu kpɔ, nukae dzɔna ne ʋumenugbagbeviɣidɔ sia xe alo xe le afi aɖe? Ele abe tsi ƒe pɔmpi si xe ene. Bile mete ŋu sina nyuie o. Emegbe ʋumenugbagbeviɣi sia dzea ƒoƒo ƒu ɖe ʋukawo kple ŋutinu siwo do ƒome kplii abe aklã ene me. Esia ate ŋu agblẽ nu le lãmenugbagbevi mawo ŋu eye wòado kplamatse woƒe dɔwɔwɔ. Menye ema ɖeɖeko o, ke ʋumenugbagbeviɣi sia si ƒo ƒu la dzea sisi gɔme ɖe ʋua me vivivi. Esia gblẽa nu le ŋutilã ŋu eye wònyea aɖi . Esia ate ŋu ahe dzesi siwo meɖea dzi ɖi o vɛ eye le ɣeyiɣi aɖe megbe la, ate ŋu ahe dɔléle vovovowo vɛ. Ɣeaɖewoɣi la, ʋumenugbagbeviɣidɔ ate ŋu anye kuxi si anɔ anyi ɣeyiɣi kpui aɖe, alo ate ŋu anye kuxi si dzina ɖe edzi vivivi eye wòyia edzi.

Aleke esia kpɔa ŋusẽ ɖe wò ŋutilã dzii?

Cholestasis ate ŋu agblẽ nu le wò ŋutilã ŋu le mɔ vovovowo nu.

Nusiwo dona tso eme le ɣeyiɣi kpui aɖe me:

Nu gbãtɔ si wògblẽnae nye ŋutinu siwo le wò ʋumenugbagbeviɣidɔ me. Ʋumenugbagbeviɣidɔ ate ŋu ana aklã, aɖuɖɔtoe, dɔgbo, alo ʋumenugbagbeviɣimɔ̃wo navuvu eye wòaxɔ abi . Esia ate ŋu ahe dzesiwo abe dɔgbo ƒe veve kple ʋuʋudedi ene vɛ. Enaa dɔlékuiwo xɔxɔ ƒe afɔkua hã dzina ɖe edzi.

Azɔ hã, esi dɔgbo suea mekpɔa ʋumenugbagbeviɣi si sɔ o ta la, ami siwo le nuɖuɖu si nèɖuna me la meɖuna nyuie o. Esia ate ŋu ana ame navuvu, nuɖuɖumaɖumaɖu, kple aɖuɖɔtoe.

Nusiwo wògblẽna le ame ŋu ɣeyiɣi didi:

Ne nɔnɔme sia yi edzi la, kuxi bubuwo ate ŋu ado mo ɖa.

• Ʋumenugbagbeviɣidɔ ƒe ƒoƒo ɖe ʋua me ate ŋu ana jaundice , si nye ŋku kple ŋutigbalẽ ƒe ɣie, kple aɖuɖɔ si nado viviti.
• Ame aɖewo ate ŋu akpɔ ʋuʋudedi sesẽ (pruritus) . Esia le alea elabena ʋumenugbagbeviɣidɔ siwo le ʋua me doa ŋusẽ lãmekawo.
• Lãmenugbagbeviwo abe aklã ene ƒe dɔdzẽ ɣeyiɣi didi ate ŋu ana abi nadze ame dzi eye wòagawɔ dɔ tegbee. Wogayɔa esia be ʋumenugbagbeviɣidɔ .
• Vitamin siwo me ami le, abe vitamin A , D, E, kple K ene, mexɔa ŋutilãa nyuie o. Esia ate ŋu ahe nunyuimakpɔɖu vɛ. Esia ate ŋu anye nusi gbɔ tsitsi ƒe gbɔdzɔgbɔdzɔ tsona, vevietɔ le ɖevi suewo gome.

Vevietɔ ɖo ŋku edzi!

Vidzidzi ƒe ʋumenugbagbeviɣidɔ le fufɔɣi dzia kuxi siwo ate ŋu ade vidadaa kple fugboea siaa ƒe agbe afɔku me ƒe afɔkua ɖe edzi. Esiawo dometɔ aɖewoe nye preeclampsia, vidzidzi kaba, kple vi kuku. Eyata ele vevie be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo enumake ne èkpɔ dzesi siawo le fufɔɣi.

Nukawo koŋ tae wòle alea ɖo?

Nu geɖe li siwo gbɔ ʋumenugbagbeviɣidɔ tsona. Le goawo katã me la, kuxi ƒomevi eve li:

Nukawoe nye ʋumenugbagbeviɣidɔ ƒe dzesiwo?

Dzesi geɖe li siwo wokpɔna zi geɖe le nɔnɔme sia me:

• Jaundice: Zi geɖe la, wò ŋutigbalẽ ƒe ɣie kple wò ŋku ƒe ɣie nyea dzesi gbãtɔ si fia be wò aklã mele dɔ wɔm nyuie o. Esia tsoa ʋumenugbagbeviɣidɔ si ƒoa ƒu ɖe ʋua me gbɔ. Etɔxɛe la, amadede aɖe si woyɔna be bilirubin si le ʋumenugbagbeviɣi me gbɔe amadede ɣi sia tsona. Ɣeaɖewoɣi la, bilirubin hã dona le aɖuɖɔ me, si ate ŋu ana aɖuɖɔa nazu amadede ɣi/blɔ viviti.
• Aɖuɖɔ si ƒe amadede le keklẽm: Esia le alea elabena ʋumenugbagbeviɣi mele zɔzɔm to dɔgboa me nyuie o, si ate ŋu ana aɖuɖɔ natrɔ. Ne ʋumenugbagbeviɣi meli be woatsɔ aɖu amiwo o la, amiawo dona kple aɖuɖɔa. Aɖuɖɔ sia ƒomevi nyea ɣie, eye eƒe amadede nyea anyi. Azɔ hã, amadede sia si me kɔ la tso bilirubin ƒe anyimanɔmanɔ gbɔ (zi geɖe la, aɖuɖɔ nɔa blɔ le bilirubin ta). Esiawo ate ŋu anɔ tsia dzi eye woƒe ʋeʋẽ sesẽ.
• Ʋuʋudedi: Esia nye dzesi bubu si wokpɔna le ʋumenugbagbeviɣidɔ me. Ʋuʋudedi si do ƒome kple ʋumenugbagbeviɣi dzɔna ne ʋumenugbagbeviɣi ƒe dze alo ʋumenugbagbeviɣiwo ƒo ƒu ɖe ʋua me eye wòʋã lãmeka siwo le gota ƒe lãmekawo. Ʋuʋudedi sia mehea ʋuʋudedi aɖeke vɛ o. Ame aɖewo sea veve ɖe ʋumenugbagbeviɣi siawo nu wu. Ame aɖewo ƒe ʋuʋudedi mebɔna o, evɔ ame bubuwo ya ƒoa nu geɖe. Ate ŋu anɔ ƒoƒom ɖe asibidɛwo, afɔkpodziwo, kple afɔwo dzi wu, eye ŋutilã bliboa ate ŋu avuvu.

Tsɔ kpe ɖe dzesi vevi siawo ŋu la, dzesi bubuwo ate ŋu ado mo ɖa le nusi gbɔ ʋumenugbagbeviɣidɔ tsona nu.

• Ƒodo ƒe vevesese
• Aɖuɖɔtoe kple ʋuʋudedi
• Ɖeɖiteameŋu

Aleke nèwɔ de dzesi esia?

Ne ʋumenugbagbeviɣidɔ ƒe dzesiwo le ŋuwò la, nu gbãtɔ si ɖɔkta awɔe nye be wòado wò ʋu aɖe kpɔ.

• Ʋudodokpɔ:Esia léa ŋku ɖe bilirubin kple ʋumenugbagbeviɣidɔ ƒe agbɔsɔsɔ si dzi ɖe edzi ŋu. Eléa ŋku ɖe ʋumemi kple aklã me dɔlékui aɖewo, abe gamma-glutamyl transferase (GGT) kple alkaline phosphatase (ALP) ene, dzi ɖe edzi hã ŋu. Esiawo ate ŋu ana míanya nusi gbɔ dɔlélea tso.
• Nɔnɔmetatawo dodokpɔ: Ne ʋudodokpɔwo ɖee fia be dɔléle le ŋuwò la, afɔɖeɖe si kplɔe ɖoe nye be nàwɔ nɔnɔmetatawo dodokpɔ atsɔ alé ŋku ɖe wò ʋumenugbagbeviɣidɔ ŋu. Esiawo ate ŋu adze egɔme kple dodokpɔ bɔbɔe siwo mewɔa nuvevi ame o abe ƒodo me ultrasound alo ƒodo me CT scan ene. Esiawo ate ŋu adi ŋutilã me xexe le ʋumenugbagbeviɣiwo me kple vuvu le ŋutinuwo me.
• Dodokpɔ siwo me wodzroa nu me: Nusiwo gbɔ ʋumenugbagbeviɣidɔ tsona dometɔ aɖewo hiã be woado ame me kpɔ be woake ɖe nusi gbɔ wòtso ŋu ahadae. Ðewohĩ ahiã be ɖɔktaa nado ʋumenugbagbeviɣiwo kpɔ alo atsɔ lãkusi sue aɖe tso aklã me (aklã me lãmenugbagbeviwo ɖeɖe) atsɔ adoe kpɔ le dodokpɔxɔ me. Le ERCP (Endoscopic Retrograde Cholangiopancreatography) , me la, ɖɔktawo ate ŋu adi kuxi siwo le ʋumenugbagbeviɣiwo ŋu ahada wo.

Aleke wowɔa atike nɛ?

Atikewɔwɔ na ʋumenugbagbeviɣidɔ nɔ te ɖe nusi gbɔ wòtso dzi.

• Nusiwo gbɔ wòtsona kpata: Woate ŋu ada nusiwo gbɔ wòtsona dometɔ aɖewo bɔbɔe vie. Woate ŋu atsɔ atike bubuwo aɖɔli atike siwo le kuxia hem vɛ. Woate ŋu ana dɔlékuiwutikewo alo dɔlékuiwutikewo na dɔlékuiwo. Woate ŋu aɖe ʋuka siwo xea mɔ na ʋukawo ɖa to dɔlékuiwo me toto abe ERCP ene dzi.
• Nusiwo gbɔ wòtsona ɣeyiɣi didi: Nusiwo hea aklãdɔléle vɛ atraɖii la dada ate ŋu asesẽ. Dɔléle aɖewo mekpɔa atike tegbee o, eye womate ŋu atrɔ abi le aklã me (cirrhosis) o. Gake agbenɔnɔ ƒe tɔtrɔ abe nuɖuɖu, kamedede, kple ahanono ene ate ŋu akpe ɖe ame ŋu wòaɖu aklãdɔ geɖe ƒe ŋgɔyiyi dzi. Le ɣeyiɣi sia me la, wò ɖɔkta ƒe susu anɔ wò dɔlélea ƒe nugbegblẽ le ame ŋu dada ŋu.

Dɔdamɔnuawo ate ŋu anye:

• Nunyiame: Nuɖuɖu ƒe tɔtrɔ kple nunyiame kpeɖeŋutɔ ate ŋu akpe ɖe ame ŋu be woaxe mɔ ɖe nunyuimakpɔɖu kple vitamin ƒe agbɔsɔsɔ si mede ame dzi o nu.
• Ursodeoxycholic acid ƒe aɖi:Zi geɖe la, wozãa atike sia tsɔ lɔ̃a aɖuɖɔtoemekpewo, gake ate ŋu akpe ɖe ʋumenugbagbeviɣidɔ hã ŋu ɣeaɖewoɣi to ʋumenugbagbeviɣidɔ dzi ɖeɖe kpɔtɔ kple ʋumenugbagbeviɣidze siwo sɔ gbɔ ɖe ʋua me ƒe ŋusẽkpɔɖeamedzi dzi ɖeɖe kpɔtɔ me.
• Naltrexone: Wozãa opioid ƒe mɔxenu sia ɣeaɖewoɣi tsɔ daa ʋuʋudedi sesẽ. Ewɔa dɔ to lãmekawo ƒe mɔ siwo ʋumenugbagbevi dzĩ siwo le ʋua me ʋãna la xexe me.
• Cholestyramine: Atike sia si ɖea ʋumemi dzi kpɔtɔna la blaa ʋumemi kple ʋumemi dze siwo le dɔgboa me, si wɔnɛ be wo dometɔ geɖe dona le aɖuɖɔ me.