Ðe nèle sesem le ɖokuiwò me be yegbɔdzɔa? Ðe wò abɔ kple afɔwo le ƒoƒom? Mina míasrɔ̃ nu tso CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) ŋu!

Ðe ɖeɖi tea ŋuwò ŋutɔ ɣeaɖewoɣi, wò abɔwo kple afɔwo tsia dzodzodzoe, alo ɖe nèsena le ɖokuiwò mea? Ɣeaɖewoɣi la, ɖewohĩ màlé to ɖe nusiawo ŋu boo o. Gake le go siwo mebɔ o me la, dzesi siawo ate ŋu anye nane si nu sẽ wu ƒe dzesi. Nɔnɔme mawo dometɔ ɖeka si mebɔ o gake wòle vevie be woanya nu tso eŋue nye CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) . Togbɔ be ŋkɔa adze abe ɖe wòdidi vie ene hã la, mina míana wòanɔ bɔbɔe.

Nukae nye CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) ƒe dɔléle si nye CIDP?

Togbɔ be ŋkɔ sia adze nu sesẽ vie hã la, ne míegbã gɔmesese si le eŋu la, míate ŋu akpɔ dɔléle sia nyuie wu.

• Nusiwo nɔa anyi didi: Esia gɔmee nye "ɣeyiɣi didi." Esia fia be CIDP meva kpata eye wòhayana kabakaba o. Etsina vivivi, le kwasiɖa enyi ya teti me. Ɣeaɖewoɣi la, dzesiawo nu fa eye emegbe wogadzena le ɣleti alo ƒe geɖe gɔ̃ hã megbe. Ele abe kuxi si gbugbɔna dzɔna ene.

• Dzoxɔxɔ: Esia fia "dɔdzẽ" . Ne míexɔ abi le míaƒe ŋutilã ƒe teƒe aɖe la, evuvuna eye wòbiãna, alo? Emae nye nusi wònye. Gake le CIDP me la, dɔdzẽ sia dzɔna le kuxi aɖe si le mía ŋutɔwo míaƒe ŋutilã ƒe dɔlélenutsiŋutete me ta . Kpuie ko la, asrafo siwo wobu be woakpɔ míaƒe ŋutilã ta la dzea mía ŋutɔwo ƒe lãmekawo dzi dzedze gɔme vodadatɔe. Woyɔa esia be ``Autoimmune Attack'' . Dzoxɔxɔ si gbɔ eme si esia hena vɛ gblẽa nu le míaƒe lãmeka siwo le gota gome ŋu . Lãmetsi siawo siwo le gota lae nye lãmeka siwo keke tso ahɔhɔ̃ kple aklã me.

• Demyelinating: Esia nye nya si me goglo vie. Ametakpɔnu aɖe le míaƒe ahɔhɔ̃mekawo ŋu ƒo xlã wo. Ele abe aŋekotoku si wotsɔ ƒo xlã elektrikka ene. Woyɔa nutsyɔnu sia be ` (Myelin Sheath)` . Myelin-kplo siae nana lãmekawo ƒe gbedasiwo zɔna kabakaba hewɔa nu pɛpɛpɛ. `(Demyelinating)` fia be myelin ƒe akɔta gblẽ alo gblẽ. Emegbe abe alesi ko ne woɖe aŋe si le ka la dzi ɖa ene la, elektrikŋusẽa dona, eye lãmekawo ƒe gbedasiwo mezɔna nyuie o.

• Polyneuropathy: "Poly" gɔmee nye "ame geɖe." "Ahɔhɔ̃mekawo ƒe dɔléle" fia be nu gblẽ le lãmekawo ŋu. Polyneuropathy fia be nu gblẽ le lãmeka geɖe siwo le ŋutilãa me ŋu le ɣeyiɣi ɖeka me. Esia ate ŋu ahe kuxi vovovowo abe lãmekawo ƒe gbɔdzɔgbɔdzɔ, lãmekawo ƒe ʋuʋu, kple lãmekawo ƒe ʋuʋu ene vɛ.

Eyata ne míagblɔe kpuie ko la, CIDP nye nɔnɔme si nɔa anyi didi si me myelin-kplu si ƒo xlã lãmeka siwo le gota la gblẽna le mía ŋutɔwo ƒe dɔlélenutsiŋutete ƒe dɔmawɔmawɔ nyuie ta, si wɔnɛ be lãmeka geɖe mewɔa dɔ nyuie o. Èse egɔmea?

Vovototo kae le Guillain-Barré Dɔléle (GBS) kple CIDP dome?

Ðewohĩ wòeÐewohĩ èse ` (Guillain-Barré Syndrome)` alo ` (GBS) .` Dɔléle si nye CIDP ɖi GBS ŋutɔ. Ðɔktawo bua CIDP be enye GBS ƒe dɔléle si nɔa anyi didi. GBS hã nye dɔléle si mebɔ o si me míaƒe dɔlélenutsiŋutete dzea lãmeka siwo le gota la dzi.

Gake vovototo vevitɔe nye ɣeyiɣi. Zi geɖe la, GBS ƒe vɔ̃ɖitɔ kekeake dzɔna le kwasiɖa eve va ɖo etɔ̃ le dzesiawo ƒe gɔmedzedze megbe. Gake ame akpa gãtɔ ƒe lãme sẽna vivivi le ema megbe. Gake CIDP nɔa anyi didi wu. Dzesiawo nu sẽna ɖe edzi vivivi le kwasiɖa enyi ya teti me .

Aleke gbegbee CIDP bɔe?

Le nyateƒe me la, CIDP nye nɔnɔme si mebɔ kura o . Numekulawo gblɔ be ame yeye siwo ŋu CIDP le le United States ƒe xexlẽme le 0.8 va ɖo 8.9 le ame 100,000 ɖesiaɖe me ƒe sia ƒe. Agbɔsɔsɔ sia lolo vie, elabena CIDP ateŋu adze ame vovovowo dzi le mɔ vovovowo nu, eye le esi dɔlélea didi sesẽ ta.

CIDP ate ŋu adzi ɖe edzi le ƒe ɖesiaɖe me.

Nukae nye CIDP ƒe dzesiwo?

CIDP ƒe dzesiwo ate ŋu ato vovo le eƒe ƒomevi nu. Gake dzesi si bɔ wue nye lãmekawo ƒe gbɔdzɔgbɔdzɔ vivivi si nɔa anyi kwasiɖa enyi ya teti. Zi geɖe la, esia gblẽa nu le ŋutilãa ƒe akpa eveawo siaa ŋu sɔsɔe. Etɔxɛe:

• Lãmetsi siwo le akɔta kple ata ƒe nuto me
• Lãmetsi siwo le abɔta kple abɔta ƒe akpa si le etame
• Asibidɛ kple asibidɛwo
• Afɔwo kple afɔbidɛwo

Bu eŋu kpɔ, kasia wòsesẽna na wò be nàfɔ tso zikpui dzi, ase le ɖokuiwò me be yemate ŋu ali atrakpui aɖeke o, alo esesẽna na wò be nàkɔ wò ɖa alo alé kplu ɖe asi. Nu siawo tɔgbi ate ŋu adzɔ.

Dzesi bubu siwo woate ŋu akpɔ dometɔ aɖewoe nye:

• Lãmetsi siwo ŋu dɔlélea le ƒe vuvu
• Asibidɛwo kple afɔbidɛwo ƒe ʋuʋu, ʋuʋudedi, alo seselelãme ƒe bu (Paresthesia) .
• Ŋutilã ƒe dadasɔ me léle ɖe asi sesẽ kple nuwɔwɔ aduadu nyuie o (abe nukikli ene) .
• Azɔlizɔzɔ sesẽ alo azɔlizɔzɔ ƒe bu keŋkeŋ
• Deep tendon reflexes ƒe bu alo gbɔdzɔgbɔdzɔ (esiae ɖɔkta ado kpɔ ne etsɔ akplɔ sue aɖe ƒo kloa) .
• Ahɔhɔ̃mekawo ƒe Vevesese. Esia nye vevesese si se le eɖokui me abe dzobibi alo elektrikŋusẽ ƒe ƒoƒo ene.

Ƒã ŋutɔ la, àte ŋu akpɔ dzesiwo abe:

• Nu mimi sesẽ (Dysphagia) kple kɔ si le etame ƒe gbɔdzɔgbɔdzɔ
• Nukpɔkpɔ Eve

Dzesi siawo ate ŋu atrɔ le ɣeyiɣi aɖe megbe. Woate ŋu adze egɔme vivivi, alo woate ŋu ayi ŋgɔ kabakaba. Ɣeaɖewoɣi la, woate ŋu ava hedzo, wo nu fa le ŋkeke ʋɛ aɖewo megbe, eye wogatrɔ gbɔ. Ne dzesi siawo le ŋuwò la, ele vevie be nàyi ɖɔkta gbɔ kaba.Ne wokpɔ dɔlélea kaba hedae la, ewɔa akpa gã aɖe le hayahaya me.

Ðe CIDP ƒomevi vovovowo lia?

Ẽ, CIDP ƒe vovototo vovovowo li, eye woƒe dzesiwo to vovo vie.

Ƒomevi si bɔ wue nye CIDP si bɔ , si nana lãmekawo gbɔdzɔna eye seselelãme ƒe dzesiwo (abe lãmetutudɔ ene) dzena le ŋutilã ƒe akpa eveawo.

Vovototo siwo mebɔ o dometɔ aɖewoe nye:

• ` (Multifocal Motor Neuropathy)`: Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ koe esia lɔ ɖe eme. Gbɔdzɔgbɔdzɔ sia hã mesɔ o, si fia be ate ŋu agblẽ nu le ŋutilã ƒe akpa ɖeka ko ŋu, alo ate ŋu akpɔ ŋusẽ ɖe teƒe geɖe dzi le mɔ vovovowo nu.
• ` (Lewis-Sumner Syndrome): Esia lɔ lãmekawo ƒe gbɔdzɔgbɔdzɔ si mesɔ o kple seselelãme ƒe dzesiwo siaa ɖe eme.
• ` (Pure Sensory CIDP)`: Esia ateŋu ahe lãmetutudɔ, vevesese, dadasɔ ƒe kuxiwo, kple azɔlizɔzɔ si mesɔ o vɛ. Gake lãmekawo ƒe gbɔdzɔgbɔdzɔ aɖeke mele eme o.
• `(Pure Motor CIDP):`: Le esia me la, woateŋu akpɔ lãmekawo ƒe gbɔdzɔgbɔdzɔ kple reflexes ƒe bu si gblẽa nu le ŋutilã ƒe akpa eveawo ŋu, gake seselelãme ƒe dzesi aɖeke mele eme o.

Numekulawo gale nu srɔ̃m tso CIDP ƒe tɔtrɔ bubuwo ŋu.

Nukae hea CIDP vɛ?

Abe alesi míedzro eme va yi ene la, numekulawo xɔe se be míaƒe dɔlélenutsiŋutete ƒe dɔmawɔmawɔ nyuie gbɔe CIDP tsona . Togbɔ be womenya nusi tututu gbɔ wòtso haɖe o hã la, míaƒe dɔlélenutsiŋutete kpɔa myelin ƒe akɔta abe futɔ ene eye emegbe wòdzea edzi dzedze gɔme (si nye dɔlélenutsiŋutete ƒe dɔwɔwɔ).

Myelin-kploae nye ametakpɔnu si ƒo xlã míaƒe lãmekawo. Exatsa ɖe lãmeka ƒe ka (axon) ƒe akpa didi la ŋu. Myelin ye nana elektrikŋusẽ ƒe ŋusẽ te ŋu zɔna to lãmekaa me nyuie. Ne myelin gblẽ la, elektrikŋusẽ siawo zɔna blewu ŋutɔ, alo wobuna kura. Emegbe "gbedasiawo" meɖoa afisi wòle be woayi o. Emae nye nusi hea CIDP ƒe dzesiwo vɛ.

Kpɔe ɖa le susu me be elektrikka aɖe si ŋu woxe mɔ ɖo nyuie. Ekplɔa elektrikŋusẽ nyuie ŋutɔ. Gake nukae adzɔ ne aŋekotoku si le ka ma dzi la do le teƒe aɖewo? Fifia si le sisim, alo me sina nyuie o, alo? Emae nye nusi dzɔna ne myelin ƒe akɔtaɖonu la gblẽ.

Aleke wowɔa dea dzesi CIDP?

CIDP didi ate ŋu asesẽ elabena dzesi vovovowo le ƒomevi vovovowo ŋu. Be nànya CIDP la, wò ɖɔkta awɔ:

• Woaɖo to wò dzesiwo nyuie eye woabia wò atikewɔwɔ ŋutinya .
• Wowɔa ŋutilãmedɔ kple ahɔhɔ̃mekawo dodokpɔ .
• Woate ŋu aɖe gbe be woawɔ dodokpɔ tɔxɛ geɖe atsɔ aɖo kpe dɔlélea dzi alo aɖe dɔléle bubuwo ɖa.

Dodokpɔ kawoe wozãna tsɔ dea dzesi CIDP?

Esiawoe nye dodokpɔ siwo ate ŋu akpe ɖe ame ŋu be woaɖo kpe CIDP dzi eye woaɖe nu bubu siwo gbɔ wòtsona ɖa:

• Electromyography (EMG) kple Nerve Conduction Tests: Dodokpɔ siawo léa ŋku ɖe wò lãmekawo kpakple lãmeka siwo kpɔa wo dzi ƒe lãmesẽ kple dɔwɔwɔ ŋu. Dodokpɔ siawo ɖea vi ŋutɔ na demyelinating tɔtrɔwo didi (lãmekawo ƒe dzesiwo ƒe kaka blewu, mɔxexe, kple bubuawo) abe CIDP ene. Esia ate ŋu akpe ɖe ame ŋu woade vovototo CIDP kple ahɔhɔ̃meka geɖe ƒe dɔléle ƒomevi bubu siwo bɔ dome.

• Spinal Tap / Lumbar Puncture: Le dodokpɔ sia me la, ɖɔkta aɖe tsɔa aŋe sue aɖe dea wò akɔta eye wòɖea wò ahɔhɔ̃mekawo ƒe tsi (CSF) ƒe kpɔɖeŋu . Woɖoa kpɔɖeŋu sia ɖe dodokpɔxɔ aɖe be woadoe kpɔ. Le amesiwo ŋu CIDP le ƒe 85% va ɖo 90% me la, ʋumenugbagbevi ɣiwo ƒe xexlẽme sɔ, gake protein ƒe agbɔsɔsɔ dzina ɖe edzi. Nu bubu siwo mesɔ o le CSF me ate ŋu afia nɔnɔme bubu aɖe.

• Magnetic Resonance Imaging (MRI) scan of the lower back: Ne lãmeka ƒe ke siwo le wò akɔta ƒe akpa si le ete la xɔa amadede si to vovo na wo nɔewo le MRI scan wɔwɔ me la, ate ŋu akpe ɖe ŋuwò nànya CIDP.

• Ʋudodokpɔ: Wò ɖɔkta ate ŋu aɖe gbe be woado ʋu kpɔ be wòaɖe dɔléle bubu siwo ate ŋu ahe ahɔhɔ̃mekawo ƒe dɔmawɔmawɔ nyuie, abe suklidɔ, vitamin ƒe anyimanɔmanɔ, lãkusidɔ, Lyme dɔléle, HIV/AIDS, kple ʋumenugbagbeviɣidɔ ene ɖa. Woate ŋu alé ŋku ɖe dɔlékuiwutike aɖewo siwo wokpɔ be wodo ƒome kple CIDP hã ŋu.

• Nerve Biopsy: Ƒã ŋutɔ la, ɖɔkta ate ŋu aɖo aɖaŋu be woawɔ nerve biopsy, si me woɖea lãmeka aɖe ɖa le hedoa eŋu kpɔ be myelin-kploa gblẽ hã.

Nukawoe nye atike siwo wozãna na CIDP?

Atikewɔwɔ vevi etɔ̃ (gbãtɔ) li na CIDP:

• Corticosteroids: Steroid-tikewo, abe prednisolone ene, kpena ɖe ame ŋu be dɔdzẽ dzi ɖena kpɔtɔna. Le ame geɖe gome la, steroid siawo ɖeɖe ate ŋu akpe ɖe ame ŋu be woaɖe dzesiawo dzi akpɔtɔ. Gake steroid ate ŋu agblẽ nu le ame ŋu vevie, eyata atike siawo zazã ɣeyiɣi didi mesɔ gbɔ o. Wò ɖɔkta ate ŋu aŋlɔ atike bubuwo (dɔlékuiwutikewo) hã na wò kpe ɖe steroid ŋu.

• Plasma Exchange / Plasmapheresis: Le atikewɔwɔ sia me la, mɔ̃ aɖe ɖea ʋumenugbagbeviɣia ɖa tso wò ʋu gbɔ, daa dɔ nɛ, eye emegbe wògbugbɔa ʋumenugbagbeviɣia kple ʋua trɔna yia wò ŋutilã me. Kpuie ko la, eɖea dɔlékuiwutike siwo gblẽa nu le ame ŋu siwo le ʋumenugbagbevi dzĩ me siwo le wò lãmekawo dzi dzem la ɖa. Zi geɖe la, kwasiɖa ʋɛ aɖewo koe ʋumenugbagbeviɣidɔ ƒe asitɔtrɔ wɔa dɔ. Ðewohĩ ahiã be nànɔ atike sia wɔm ahanɔ etɔm ɣleti geɖe, alo ƒe geɖe gɔ̃ hã.

• Dɔlélenutsiŋutete ƒe Dɔdamɔnu (IVIG): Le atikewɔwɔ sia me la, wodoa protein siwo woyɔna be immunoglobulins (protein siwo míaƒe dɔlélenutsiŋutete wɔna le dzɔdzɔme nu be woadze amedzidzelawo dzi) to ʋuka me (IV). Wokpɔa dɔlélenutsiŋutete sia tso ame akpe geɖe siwo le lãmesẽ me ƒe ʋu me. IVIG ate ŋu aɖe nusiwo wò dɔlélenutsiŋutete gblẽna le wò lãmekawo ŋu dzi akpɔtɔ. Woate ŋu ana IVIG le agbɔsɔsɔ gã ŋutɔ me le gɔmedzedzea me, eye ahiã be nàxɔ atike sia ɣeaɖewoɣi hena ɣleti geɖe, alo ƒe geɖe gɔ̃ hã.

Numekulawo le nu srɔ̃m tso atike bubu siwo wozãna na CIDP ŋu fifia. Mɔnukpɔkpɔ ate ŋu asu asiwò hã be nàkpɔ gome le dɔdamɔnu dodokpɔ aɖe me na CIDP. Ðo dze kple wò ɖɔkta tso esia ŋu.

Aleke agbe le le CIDP gome? (Nyagblɔɖi) .

Alesi dɔlélea ate ŋu akpɔe ɣeyiɣi didi la nɔ te ɖe nu geɖe dzi:

• Ƒe si nèxɔ esime CIDP dze egɔme.
• Alesi dɔlélea va doa mo ɖa kple dɔlélea ƒomevi .
• Alesi wokpɔ dɔlélea kaba eye wodze edada gɔmee .
• Alesi wò ŋutilã wɔa nu ɖe ​​atikewɔwɔ ŋu le gɔmedzedzea me .

Ame siwo ŋu CIDP le la dometɔ siwo ade 90% ate ŋu ada gbe le wo ŋu to atikewɔwɔ me. Gake ame siwo ade 50% ƒe dɔlélea gadzena ake. Le goawo katã me la, amesiwo ŋu wokpɔ CIDP le le woƒe ɖevime ƒe ɣeyiɣi didi ƒe nyagblɔɖi nyo. Ne mèkpɔ CIDP ƒe atike aɖeke o la, lãmekawo ate ŋu agblẽ tegbee, si ate ŋu ana nàzu nuwɔametɔ aɖewo.

Wò ɖɔkta ate ŋu ana nàkpɔ nusi nàkpɔ mɔ na le etsɔme le wò nɔnɔme tɔxɛa nu.

Ðe CIDP ɖea agbenɔƒe dzi kpɔtɔnaa?

CIDP menye dɔléle si wua ame o. Zi geɖe la, amesiwo ŋu dɔléle sia le ƒe agbenɔƒe sɔ kple amesi ŋu dɔlélea mele o. Eyata naneke meli si ŋu woatsi dzi ɖo o.

Ðe woate ŋu axe mɔ ɖe CIDP nua?

Esi numekulawo mekpɔ nusi koŋ gbɔ CIDP tso haɖe o ta la, mɔ aɖeke meli si wonya fifia si dzi woato axe mɔ ɖe dɔlélea ƒe dzɔdzɔ nu o.

Ɣekaɣie wòle be makpɔ ɖɔkta? / Ɣekaɣie wòle be mayi xɔ si me wowɔa dɔ kpata le?

Ne wokpɔ CIDP le ŋuwò la, ele be nàyi ɖɔkta gbɔ edziedzi be wòalé ŋku ɖe wò dzesiwo ŋu ahaxɔ atike. CIDP ƒe dzesiwo ate ŋu ava eye woadzo ɣleti geɖe alo ƒe geɖe gɔ̃ hã, eyata ate ŋu ahiã be woayi edzi awɔ atike na wo.

Ƒã ŋutɔ hafi CIDP ate ŋu akpɔ ŋusẽ ɖe lãmeka siwo hiã be woagbɔ ya dzi . Ne gbɔgbɔtsixe tsia ƒowò la , ƒo ka na 911 (alo xexlẽdzesi si le mia gbɔ) enumake, alo yi xɔ si te ɖe ŋuwò si kpɔa nudzɔdzɔ kpatawo gbɔ. Esia nye nudzɔdzɔ kpata aɖe.

Mlɔeba la, nu siwo dzi wòle be woaɖo ŋkui

Ate ŋu ado vɔvɔ̃ na wò be nàse le ɖokuiwò me be yemate ŋu aɖu yeƒe ŋutilã dzi o. Gake nya nyuiae nye be woate ŋu ada CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) ƒe dzesiwo, vevietɔ ne èdze atikewɔwɔ gɔme kaba. Ðo ŋku edzi be wò atikewɔlawo ƒe ƒuƒoƒoa le gbɔwò le afɔɖeɖe ɖesiaɖe si nàwɔ atsɔ akpɔ nɔnɔme sia gbɔe me. Eyata dzi ƒo eye nàwɔ ɖe wò ɖɔkta ƒe aɖaŋuɖoɖo dzi.

` CIDP, Ahɔhɔ̃mekawo ƒe Dɔléle, Lãmetsiŋusẽ ƒe Gbɔdzɔgbɔdzɔ, Dɔlélenutsiŋutete, Dɔlélenutsiŋutete, Myelin, Lãmetsiŋusẽ, CIDP Dɔdamɔnu, Ahɔhɔ̃mekawo ƒe Dɔléle si Nɔa Anyi Didi